PT911331E - Compostos de dibenzoxazepina substituidos composicoes farmaceuticas e metodos de utilizacao - Google Patents
Compostos de dibenzoxazepina substituidos composicoes farmaceuticas e metodos de utilizacaoInfo
- Publication number
- PT911331E PT911331E PT99101029T PT99101029T PT911331E PT 911331 E PT911331 E PT 911331E PT 99101029 T PT99101029 T PT 99101029T PT 99101029 T PT99101029 T PT 99101029T PT 911331 E PT911331 E PT 911331E
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- methods
- formula
- dibenzoxazepine compounds
- compounds pharmaceutical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69565491A | 1991-05-03 | 1991-05-03 | |
PCT/US1992/003028 WO1992019617A2 (en) | 1991-05-03 | 1992-04-16 | Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
PT911331E true PT911331E (pt) | 2004-03-31 |
Family
ID=24793923
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95116872T PT694546E (pt) | 1991-05-03 | 1992-04-29 | Complexos de acido fenilboronico |
PT99101029T PT911331E (pt) | 1991-05-03 | 1992-04-29 | Compostos de dibenzoxazepina substituidos composicoes farmaceuticas e metodos de utilizacao |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95116872T PT694546E (pt) | 1991-05-03 | 1992-04-29 | Complexos de acido fenilboronico |
Country Status (12)
Country | Link |
---|---|
EP (5) | EP0583421B1 (pt) |
JP (1) | JP3222891B2 (pt) |
AT (2) | ATE181329T1 (pt) |
AU (1) | AU2246292A (pt) |
CA (1) | CA2108903C (pt) |
DE (2) | DE69231298T2 (pt) |
DK (2) | DK0694545T3 (pt) |
ES (2) | ES2149305T3 (pt) |
GR (2) | GR3030992T3 (pt) |
IE (2) | IE921410A1 (pt) |
PT (2) | PT694546E (pt) |
WO (1) | WO1992019617A2 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180720A (en) * | 1991-05-03 | 1993-01-19 | G. D. Searle & Co. | 2- and 3-alkoxy or hydroxy-8-substituted-dibenz[b,f]-[1,4]oxazepine-10(11H)-carboxylic acid, substituted hydrazides and methods for treating pain |
US5378840A (en) * | 1992-04-16 | 1995-01-03 | G. D. Searle & Co. | Substituted dibenzoxazepine compounds |
US5182272A (en) * | 1991-05-03 | 1993-01-26 | G. D. Searle & Co. | 8-substituted-dibenz[b,f][1,4]oxazepine-10(11)-carboxylic acid, substituted hydrazides, pharmaceutical compositions, and methods for treating pain |
US5212169A (en) * | 1991-10-31 | 1993-05-18 | G. D. Searle & Co. | Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
US5304644A (en) * | 1992-04-15 | 1994-04-19 | G. D. Searle & Co. | 1-,2-,3-,4-,5-,6-,7-,8- and/or 9 substituted dibenzoxazepine compounds, pharmaceutical compositions and methods for treating pain |
CA2113787A1 (en) * | 1993-01-29 | 1994-07-30 | Nobuyuki Hamanaka | Carbocyclic sulfonamides |
US5395932A (en) * | 1993-04-30 | 1995-03-07 | G. D. Searle & Co. | 2,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5354746A (en) * | 1993-06-01 | 1994-10-11 | G. D. Searle & Co. | Squaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5354747A (en) * | 1993-06-16 | 1994-10-11 | G. D. Searle & Co. | 2-, 3-, 4-, 5-, 6-, 7-, 8-, 9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
US5461047A (en) * | 1993-06-16 | 1995-10-24 | G. D. Searle & Co. | 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use |
US5420270A (en) * | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5424424A (en) * | 1993-10-07 | 1995-06-13 | G. D. Searle & Co. | Tartaric acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5488046A (en) * | 1993-11-03 | 1996-01-30 | G. D. Searle & Co. | Carbamic acid derivatives of substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
US5449675A (en) * | 1994-06-09 | 1995-09-12 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine urea compounds, pharmaceutical compositions and methods of use |
US5441950A (en) * | 1994-06-09 | 1995-08-15 | G. D. Searle & Co. | Substituted dibenzoxazepine and dibenzthiazepine carbamate compounds, pharmaceutical compositions and methods of use |
GB9720270D0 (en) | 1997-09-25 | 1997-11-26 | Pharmagene Lab Limited | Medicaments for the treatment of migraine |
CA2440374A1 (en) * | 2001-03-14 | 2002-09-19 | Takayuki Maruyama | A pharmaceutical composition for the treatment of depression comprising the ep1 antagonist as active ingredient |
AU2002354056A1 (en) * | 2001-11-19 | 2003-06-10 | Ono Pharmaceutical Co., Ltd. | Remedies for urinary frequency |
JO2735B1 (en) | 2003-01-30 | 2013-09-15 | هيلسين هيلث كير أس ايه. | Liquid pharmaceutical formations of balloonosterone |
US8598219B2 (en) | 2003-01-30 | 2013-12-03 | Helsinn Healthcare Sa | Liquid pharmaceutical formulations of palonosetron |
US8710045B2 (en) | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
BRPI0807942A2 (pt) | 2007-02-16 | 2014-07-01 | Ono Pharmaceutical Co | Agente terapêutico para distúrbio de excreção urinária |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3624104A (en) * | 1969-10-27 | 1971-11-30 | Searle & Co | Aralkanoyl derivatives of dibenzoxazepine-n-carboxylic acid hydrazides |
US3917649A (en) * | 1971-03-23 | 1975-11-04 | Searle & Co | Dibenzoxazepine N-carboxylic acid hydrazides and derivatives |
GB1522003A (en) * | 1975-10-17 | 1978-08-23 | Searle & Co | 1-acyl-2-(8-chloro-10,11-dihydrodibenz-(b,f)(1,4)-oxazepine-10-carbonyl)hydrazines |
US4045442A (en) * | 1976-01-05 | 1977-08-30 | G. D. Searle & Co. | 1-(Substituted amino)alkanoyl-2-(dibenzoxazepine-10-carbonyl)hydrazines and derivatives thereof |
US4704386A (en) * | 1985-08-29 | 1987-11-03 | G. D. Searle & Co. | 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(phenylsulfinyl-, and phenylsulfonyl)alkanoyl]hydrazides |
-
1992
- 1992-04-16 ES ES95116871T patent/ES2149305T3/es not_active Expired - Lifetime
- 1992-04-16 ES ES92914560T patent/ES2133324T3/es not_active Expired - Lifetime
- 1992-04-16 DE DE69231298T patent/DE69231298T2/de not_active Expired - Fee Related
- 1992-04-16 DK DK95116871T patent/DK0694545T3/da active
- 1992-04-16 CA CA002108903A patent/CA2108903C/en not_active Expired - Fee Related
- 1992-04-16 JP JP51183892A patent/JP3222891B2/ja not_active Expired - Fee Related
- 1992-04-16 AU AU22462/92A patent/AU2246292A/en not_active Abandoned
- 1992-04-16 DE DE69229442T patent/DE69229442T2/de not_active Expired - Fee Related
- 1992-04-16 AT AT92914560T patent/ATE181329T1/de not_active IP Right Cessation
- 1992-04-16 WO PCT/US1992/003028 patent/WO1992019617A2/en active IP Right Grant
- 1992-04-16 DK DK92914560T patent/DK0583421T3/da active
- 1992-04-16 EP EP92914560A patent/EP0583421B1/en not_active Expired - Lifetime
- 1992-04-16 AT AT95116871T patent/ATE194987T1/de not_active IP Right Cessation
- 1992-04-16 EP EP95116871A patent/EP0694545B1/en not_active Expired - Lifetime
- 1992-04-29 EP EP95116872A patent/EP0694546B1/en not_active Expired - Lifetime
- 1992-04-29 PT PT95116872T patent/PT694546E/pt unknown
- 1992-04-29 EP EP99101029A patent/EP0911331B1/en not_active Expired - Lifetime
- 1992-04-29 PT PT99101029T patent/PT911331E/pt unknown
- 1992-04-29 EP EP92107328A patent/EP0512400B1/en not_active Expired - Lifetime
- 1992-07-01 IE IE141092A patent/IE921410A1/en not_active IP Right Cessation
- 1992-07-01 IE IE20000774A patent/IE20000774A1/en not_active IP Right Cessation
-
1999
- 1999-08-18 GR GR990402070T patent/GR3030992T3/el unknown
-
2000
- 2000-10-20 GR GR20000402337T patent/GR3034650T3/el not_active IP Right Cessation
Also Published As
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