DE69224733T2 - Alpha-2-3-Sialyltransferase - Google Patents

Alpha-2-3-Sialyltransferase

Info

Publication number
DE69224733T2
DE69224733T2 DE69224733T DE69224733T DE69224733T2 DE 69224733 T2 DE69224733 T2 DE 69224733T2 DE 69224733 T DE69224733 T DE 69224733T DE 69224733 T DE69224733 T DE 69224733T DE 69224733 T2 DE69224733 T2 DE 69224733T2
Authority
DE
Germany
Prior art keywords
sialyltransferase
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69224733T
Other languages
English (en)
Other versions
DE69224733D1 (de
Inventor
Katsutoshi Sasaki
Etsuyo Watanabe
Tatsunari Nishi
Susumu Sekine
Nobuo Hanai
Mamoru Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE69224733D1 publication Critical patent/DE69224733D1/de
Application granted granted Critical
Publication of DE69224733T2 publication Critical patent/DE69224733T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69224733T 1991-12-17 1992-12-17 Alpha-2-3-Sialyltransferase Expired - Lifetime DE69224733T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33366191 1991-12-17
JP9104492 1992-04-10

Publications (2)

Publication Number Publication Date
DE69224733D1 DE69224733D1 (de) 1998-04-16
DE69224733T2 true DE69224733T2 (de) 1998-09-10

Family

ID=26432525

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224733T Expired - Lifetime DE69224733T2 (de) 1991-12-17 1992-12-17 Alpha-2-3-Sialyltransferase

Country Status (3)

Country Link
US (2) US5384249A (de)
EP (1) EP0552470B1 (de)
DE (1) DE69224733T2 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5858751A (en) * 1992-03-09 1999-01-12 The Regents Of The University Of California Compositions and methods for producing sialyltransferases
US5654636A (en) * 1994-11-14 1997-08-05 The Board Of Trustees Of The University Of Illinois Method and apparatus for NMR spectroscopy of nanoliter volume samples
JP4051416B2 (ja) 1995-06-15 2008-02-27 クルーセル ホランド ベスローテン フェンノートシャップ 遺伝子治療に使用されるヒト組換えアデノウイルス用のパッケージングシステム
EP0759470B1 (de) * 1995-06-29 2006-10-25 Takara Bio Inc. Für einen Endoglycoceramidase-Aktivator kodierendes Gen
AUPN658795A0 (en) * 1995-11-15 1995-12-07 Commonwealth Scientific And Industrial Research Organisation Method of producing alpha 2, 3 sialyltransferase
AU4220297A (en) * 1996-09-13 1998-04-02 Kyowa Hakko Kogyo Co. Ltd. Processes for producing sugar nucleotides and complex carbohydrates
US6689604B1 (en) * 1998-03-20 2004-02-10 National Research Council Of Canada Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses
EP1103604A4 (de) * 1998-07-29 2002-10-31 Kyowa Hakko Kogyo Kk Neue polypeptide
US6194178B1 (en) 1998-09-03 2001-02-27 Synsorb Biotech Inc. Method for the production of sialylated oligosaccharides
US20050164386A1 (en) * 1999-04-15 2005-07-28 Uytdehaag Alphonsus G. Overexpression of enzymes involved in post-translational protein modifications in human cells
US20050170463A1 (en) * 1999-04-15 2005-08-04 Abraham Bout Recombinant protein production in permanent amniocytic cells that comprise nucleic acid encoding adenovirus E1A and E1B proteins
US6855544B1 (en) * 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
US7297680B2 (en) * 1999-04-15 2007-11-20 Crucell Holland B.V. Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
US7604960B2 (en) * 1999-04-15 2009-10-20 Crucell Holland B.V. Transient protein expression methods
US8236561B2 (en) * 1999-04-15 2012-08-07 Crucell Holland B.V. Efficient production of IgA in recombinant mammalian cells
US6280989B1 (en) 1999-06-17 2001-08-28 Dmitri Kapitonov Sialyltransferases
US7527961B2 (en) * 1999-11-26 2009-05-05 Crucell Holland B.V. Production of vaccines
US7521220B2 (en) * 1999-11-26 2009-04-21 Crucell Holland B.V. Production of vaccines
US7192759B1 (en) 1999-11-26 2007-03-20 Crucell Holland B.V. Production of vaccines
KR100604258B1 (ko) * 1999-12-30 2006-07-31 씨제이 주식회사 당단백질의 생체내 활성을 증가시키는 방법
US7214660B2 (en) * 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
NZ533124A (en) * 2001-12-07 2005-11-25 Crucell Holland B Production of viruses, viral isolates and vaccines
US8524477B2 (en) * 2002-10-29 2013-09-03 Crucell Holland B.V. Methods to obtain recombinant proteins with increased sialylation from cells that express adenovirus E1A protein, and proteins obtained thereby
CN100383238C (zh) * 2003-05-09 2008-04-23 克鲁塞尔荷兰公司 E1-永生化的细胞培养物及培养所述细胞以提高从中获取的产物产量的方法
EP1626992B1 (de) * 2003-05-23 2010-06-02 Crucell Holland B.V. Herstellung von rekombinanten igm in den per.c6 zellen
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US20080300173A1 (en) 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
EP1814573B1 (de) 2004-10-29 2016-03-09 ratiopharm GmbH Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
AU2011203144B2 (en) * 2004-12-30 2012-08-16 Crucell Holland B.V. Methods to obtain recombinant proteins with increased sialylation from cells that express adenovirus E1A protein, and proteins obtained thereby
CN101090973B (zh) * 2004-12-30 2012-03-28 克鲁塞尔荷兰公司 从表达腺病毒e1a蛋白的细胞中获得唾液酸化增加的重组蛋白质的方法及由此获得的蛋白质
CA2593682C (en) * 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) * 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) * 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
JP2009515508A (ja) * 2005-08-19 2009-04-16 ネオス テクノロジーズ インコーポレイテッド グリコｐｅｇ化因子ｖｉｉおよび因子ｖｉｉａ
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US7642078B2 (en) 2005-12-28 2010-01-05 Crucell Holland B.V. Methods to obtain recombinant proteins with increased sialylation from cells that express adenovirus E1A protein, and proteins obtained thereby
JP2009544327A (ja) * 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
EP2054521A4 (de) * 2006-10-03 2012-12-19 Novo Nordisk As Verfahren zur reinigung von polypeptid-konjugate
AU2007319657B9 (en) * 2006-10-04 2019-10-31 Novo Nordisk A/S Glycerol linked pegylated sugars and glycopeptides
EP2081589B1 (de) * 2006-11-16 2010-10-06 Crucell Holland B.V. Komplementierung von faktor xi-mangel durch faktor v-mutanten
KR20150064246A (ko) * 2007-04-03 2015-06-10 바이오제너릭스 게엠베하 글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
KR100886650B1 (ko) * 2007-04-13 2009-03-06 주식회사 진켐 신규 ２，３―시알릭 전이효소 및 이를 이용한 말단에갈락토오스를 포함하는 물질의 제조방법
ES2551123T3 (es) 2007-06-12 2015-11-16 Ratiopharm Gmbh Proceso mejorado para la producción de azúcares de nucleótido
US20100286067A1 (en) * 2008-01-08 2010-11-11 Biogenerix Ag Glycoconjugation of polypeptides using oligosaccharyltransferases
CN101965200B (zh) 2008-02-27 2013-06-19 诺沃-诺迪斯克有限公司 缀合的因子ⅷ分子

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047335A (en) * 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
JPH05504480A (ja) * 1990-02-14 1993-07-15 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン 糖タンパク質、糖脂質上の、又は遊離分子としてのオリゴ糖構造の合成のための、並びにこれらの構造を決定するクローン化した遺伝配列の単離のための方法及び生成物
DE4028800A1 (de) * 1990-09-11 1992-03-12 Behringwerke Ag Gentechnische sialylierung von glykoproteinen
SK108894A3 (en) * 1992-03-09 1995-07-11 Univ California Sialyltransferases and isolated dna fraction coding sialyltransferases

Also Published As

Publication number Publication date
EP0552470B1 (de) 1998-03-11
US5384249A (en) 1995-01-24
DE69224733D1 (de) 1998-04-16
EP0552470A1 (de) 1993-07-28
US5494790A (en) 1996-02-27

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Owner name: KYOWA HAKKO KIRIN CO., LTD., TOKYO, JP

R071 Expiry of right

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