DE69018130D1 - DNA-Fragment, das ein für Kreatininamidohydrolase kodierendes Gen enthält. - Google Patents

DNA-Fragment, das ein für Kreatininamidohydrolase kodierendes Gen enthält.

Info

Publication number
DE69018130D1
DE69018130D1 DE69018130T DE69018130T DE69018130D1 DE 69018130 D1 DE69018130 D1 DE 69018130D1 DE 69018130 T DE69018130 T DE 69018130T DE 69018130 T DE69018130 T DE 69018130T DE 69018130 D1 DE69018130 D1 DE 69018130D1
Authority
DE
Germany
Prior art keywords
dna fragment
fragment containing
gene coding
creatinine amidohydrolase
amidohydrolase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69018130T
Other languages
English (en)
Other versions
DE69018130T2 (de
Inventor
Kazumi Yamamoto
Masanori Oka
Toshiro Kikuchi
Shigenori Emi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyobo Co Ltd
Original Assignee
Toyobo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyobo Co Ltd filed Critical Toyobo Co Ltd
Publication of DE69018130D1 publication Critical patent/DE69018130D1/de
Application granted granted Critical
Publication of DE69018130T2 publication Critical patent/DE69018130T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69018130T 1989-06-16 1990-06-14 DNA-Fragment, das ein für Kreatininamidohydrolase kodierendes Gen enthält. Expired - Fee Related DE69018130T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1152182A JP2527035B2 (ja) 1989-06-16 1989-06-16 クレアチニン・アミドヒドロラ―ゼをコ―ドする遺伝子を含有するｄｎａ断片、該ｄｎａ断片を有する組換えベクタ―及び該組換えベクタ―を有する形質転換体、並びにクレアチニン・アミドヒドロラ―ゼの製造方法

Publications (2)

Publication Number Publication Date
DE69018130D1 true DE69018130D1 (de) 1995-05-04
DE69018130T2 DE69018130T2 (de) 1995-09-14

Family

ID=15534848

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69018130T Expired - Fee Related DE69018130T2 (de) 1989-06-16 1990-06-14 DNA-Fragment, das ein für Kreatininamidohydrolase kodierendes Gen enthält.

Country Status (4)

Country Link
US (1) US5627065A (de)
EP (1) EP0402929B1 (de)
JP (1) JP2527035B2 (de)
DE (1) DE69018130T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198785B2 (en) * 2003-12-09 2007-04-03 Brown University Systems and methods related to degradation of uremic toxins
ATE541035T1 (de) 2006-04-25 2012-01-15 Toyo Boseki Modifizierte creatininamid-hydrolase mit verbesserter substrataffinität und reagenszusammensetzung zur bestimmung von creatinin
JP5130480B2 (ja) * 2007-09-27 2013-01-30 東洋紡株式会社 キレート剤耐性が向上したクレアチニンアミドヒドロラーゼ改変体
WO2009041409A1 (ja) 2007-09-27 2009-04-02 Toyo Boseki Kabushiki Kaisha クレアチニンアミドヒドロラーゼ改変体
JP5130479B2 (ja) * 2007-09-27 2013-01-30 東洋紡株式会社 クレアチニンアミドヒドロラーゼの比活性を向上させる方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2122298C3 (de) * 1971-05-05 1979-02-22 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Gewinnung von Creatininamidohydrolase
DE2122255C3 (de) * 1971-05-05 1987-01-22 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur spezifischen Bestimmung von Creatinin
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
DE3500184A1 (de) * 1985-01-04 1986-08-14 Boehringer Mannheim Gmbh, 6800 Mannheim Mikroorganismus und plasmid fuer konstitutive creatinamidinohydrolase-bildung sowie verfahren zur herstellung derselben
JPS6437292A (en) * 1987-08-04 1989-02-07 Toyo Jozo Kk Dna having genetic information of creatinase and use thereof

Also Published As

Publication number Publication date
JPH0319690A (ja) 1991-01-28
EP0402929B1 (de) 1995-03-29
US5627065A (en) 1997-05-06
EP0402929A1 (de) 1990-12-19
JP2527035B2 (ja) 1996-08-21
DE69018130T2 (de) 1995-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee