BRPI0407811A - composto derivados de pirazolopiridina, processo para a preparação dos mesmos, composição farmacêutica e respectivos uso - Google Patents

composto derivados de pirazolopiridina, processo para a preparação dos mesmos, composição farmacêutica e respectivos uso

Info

Publication number
BRPI0407811A
BRPI0407811A BRPI0407811-0A BRPI0407811A BRPI0407811A BR PI0407811 A BRPI0407811 A BR PI0407811A BR PI0407811 A BRPI0407811 A BR PI0407811A BR PI0407811 A BRPI0407811 A BR PI0407811A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical composition
pyrazolopyridine derivatives
compounds
pyrazolopyridine
Prior art date
Application number
BRPI0407811-0A
Other languages
English (en)
Inventor
Rosales Carmen Almansa
Bernado Marina Virgili
Original Assignee
Uriach Y Compania S A J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32930978&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0407811(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from ES200300640A external-priority patent/ES2214150B1/es
Priority claimed from ES200300727A external-priority patent/ES2214976B1/es
Application filed by Uriach Y Compania S A J filed Critical Uriach Y Compania S A J
Publication of BRPI0407811A publication Critical patent/BRPI0407811A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"COMPOSTOS DERIVADOS DE PIRAZOLOPIRIDINA, PROCESSO PARA A PREPARAçãO DOS MESMOS, COMPOSIçãO FARMACêUTICA E RESPECTIVOS USO". A presente invenção refere-se aos compostos da fórmula I, e os sais, os solvatos e as pró-drogas dos mesmos, em que os significados para os vários substituintes são como divulgados na descrição. Estes compostos são úteis como inibidores da p38 quinase.
BRPI0407811-0A 2003-02-27 2004-02-27 composto derivados de pirazolopiridina, processo para a preparação dos mesmos, composição farmacêutica e respectivos uso BRPI0407811A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES200300640A ES2214150B1 (es) 2003-02-27 2003-02-27 "nuevos derivados de pirazolopiridinas".
ES200300727A ES2214976B1 (es) 2003-03-14 2003-03-14 "nuevos derivados de pirazolopiridinas".
ES200302504 2003-10-27
PCT/EP2004/001974 WO2004076450A1 (en) 2003-02-27 2004-02-27 Pyrazolopyridine derivates

Publications (1)

Publication Number Publication Date
BRPI0407811A true BRPI0407811A (pt) 2006-02-14

Family

ID=32930978

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407811-0A BRPI0407811A (pt) 2003-02-27 2004-02-27 composto derivados de pirazolopiridina, processo para a preparação dos mesmos, composição farmacêutica e respectivos uso

Country Status (30)

Country Link
US (3) US7468376B2 (pt)
EP (1) EP1611131B1 (pt)
JP (1) JP4814783B2 (pt)
KR (1) KR101312736B1 (pt)
AR (1) AR043416A1 (pt)
AT (1) ATE481402T1 (pt)
AU (1) AU2004215644B2 (pt)
BR (1) BRPI0407811A (pt)
CA (1) CA2515197C (pt)
CL (1) CL2004000398A1 (pt)
CY (1) CY1111544T1 (pt)
DE (1) DE602004029145D1 (pt)
DK (1) DK1611131T3 (pt)
EC (2) ECSP056041A (pt)
HK (1) HK1085214A1 (pt)
HR (1) HRP20050682B1 (pt)
IL (1) IL196021A (pt)
IS (1) IS2875B (pt)
MX (1) MXPA05009069A (pt)
NO (1) NO331917B1 (pt)
NZ (1) NZ541836A (pt)
PE (1) PE20050521A1 (pt)
PL (1) PL378296A1 (pt)
PT (1) PT1611131E (pt)
RS (1) RS51768B (pt)
RU (1) RU2359971C2 (pt)
SI (1) SI1611131T1 (pt)
TW (1) TWI325865B (pt)
UA (1) UA81453C2 (pt)
WO (1) WO2004076450A1 (pt)

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ECSP12006041A (es) 2012-12-28
US7468376B2 (en) 2008-12-23
IS2875B (is) 2014-04-15
PT1611131E (pt) 2010-12-20
RU2005130020A (ru) 2006-07-10
IS7939A (is) 2005-07-14
RU2359971C2 (ru) 2009-06-27
NO20053647L (no) 2005-10-18
AU2004215644A1 (en) 2004-09-10
US20090286983A1 (en) 2009-11-19
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US20060167040A1 (en) 2006-07-27
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