ATE420066T1 - Amidoacetonitrilderivate - Google Patents

Amidoacetonitrilderivate

Info

Publication number
ATE420066T1
ATE420066T1 AT04797665T AT04797665T ATE420066T1 AT E420066 T1 ATE420066 T1 AT E420066T1 AT 04797665 T AT04797665 T AT 04797665T AT 04797665 T AT04797665 T AT 04797665T AT E420066 T1 ATE420066 T1 AT E420066T1
Authority
AT
Austria
Prior art keywords
amidoacetonitril
derivatives
amidoacetonitril derivatives
Prior art date
Application number
AT04797665T
Other languages
English (en)
Inventor
Noelle Gauvry
Thomas Goebel
Pierre Ducray
Francois Pautrat
Ronald Kaminsky
Martin Jung
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE420066T1 publication Critical patent/ATE420066T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/14Ectoparasiticides, e.g. scabicides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/32Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
AT04797665T 2003-11-06 2004-11-05 Amidoacetonitrilderivate ATE420066T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03025290 2003-11-06
GBGB0402677.9A GB0402677D0 (en) 2003-11-06 2004-02-06 Organic compounds

Publications (1)

Publication Number Publication Date
ATE420066T1 true ATE420066T1 (de) 2009-01-15

Family

ID=34575667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04797665T ATE420066T1 (de) 2003-11-06 2004-11-05 Amidoacetonitrilderivate

Country Status (22)

Country Link
US (2) US7494956B2 (de)
EP (1) EP1682493B8 (de)
JP (1) JP4319680B2 (de)
KR (1) KR100793462B1 (de)
CN (1) CN100447130C (de)
AR (1) AR046322A1 (de)
AT (1) ATE420066T1 (de)
AU (1) AU2004287611B2 (de)
BR (1) BRPI0416294B1 (de)
CA (1) CA2544741C (de)
DE (1) DE602004018967D1 (de)
DK (1) DK1682493T3 (de)
ES (1) ES2317070T3 (de)
GB (1) GB0402677D0 (de)
MX (1) MXPA06005036A (de)
NZ (1) NZ546830A (de)
PL (1) PL1682493T3 (de)
PT (1) PT1682493E (de)
RU (1) RU2370485C2 (de)
SI (1) SI1682493T1 (de)
TW (1) TWI342875B (de)
WO (1) WO2005044784A1 (de)

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GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
ES2526614T3 (es) 2004-03-05 2015-01-13 Nissan Chemical Industries, Ltd. Compuesto de benzamida sustituida con isoxazolina y agente de control de organismos nocivos
AR051761A1 (es) * 2004-11-09 2007-02-07 Novartis Ag Compuestos organicos
RU2425825C2 (ru) * 2007-02-09 2011-08-10 Пфайзер Лимитед Амидоацетонитрильные производные, содержащие их фармацевтические композиции и их применение в изготовлении лекарственного средства
UA97388C2 (ru) * 2007-02-09 2012-02-10 Пфайзер Лімітед Противопаразитарные агенты
CA2678149C (en) * 2007-02-21 2013-04-16 Pfizer Limited Benzofuran antiparasitic agents
PT3428148T (pt) 2007-05-15 2020-10-13 Aventis Agriculture Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e seu método de utilização
TR201807554T4 (tr) 2007-06-07 2018-06-21 Bayer Animal Health Gmbh Ektoparazitlerin kontrolü.
MX368680B (es) 2007-06-27 2019-10-11 Du Pont Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga.
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
AU2009307736B2 (en) 2008-10-21 2015-02-05 Boehringer Ingelheim Animal Health USA Inc. Thioamide compounds, method of making and method of using thereof
LT3050874T (lt) 2008-11-14 2019-04-10 Merial Inc. Enantiomeriškai praturtinti arilazol-2-ilo cianetilamino paraziticidiniai junginiai
US8168681B2 (en) 2008-12-03 2012-05-01 Novartis Ag Amidoacetonitrile compounds and pesticidal composition thereof
GB0905365D0 (en) 2009-03-27 2009-05-13 Norbrook Lab Ltd A topical parasiticide composition
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
EP2314292A1 (de) 2009-10-20 2011-04-27 Novartis AG Endoparasitisch wirkende Zusammensetzungen
UY33282A (es) * 2010-03-25 2011-09-30 Novartis Ag Composiciones endoparasiticidas
EP2768497A1 (de) 2011-10-19 2014-08-27 Zoetis LLC Verwendung von aminoacetonitrilderivaten gegen endoparasiten
NZ630807A (en) * 2012-03-23 2016-04-29 Pitney Pharmaceuticals Pty Ltd Kinase inhibitors for the treatment of cancer
US8822689B2 (en) 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
CN103030575B (zh) * 2013-01-04 2014-10-01 中国农业大学 一类双氰基酰胺化合物及其合成方法与应用
AR094961A1 (es) 2013-03-15 2015-09-09 Lilly Co Eli 1-hidroxi-benzooxaboroles como agentes antiparasitarios
EP2821412A1 (de) * 2013-07-01 2015-01-07 Universität Zürich Organometallische 2-cyano-2-aminobenzoat-propyl-Derivate und deren Verwendung als Anthelmintika
AU2014286221B2 (en) * 2013-07-01 2018-05-31 The University Of Melbourne N-(1-cyano-2-hydroxy-1-methyl-ethyl)-4-(trifluoromethylsulfanyl)benzamide derivatives for use as nematocidal drugs
US9907778B2 (en) 2013-09-13 2018-03-06 Pitney Pharmaceuticals Pty Limited Anticancer agent comprising aminoacetonitrile compound as active ingredient
BR112016006501A2 (pt) * 2013-09-26 2017-08-01 Univ Melbourne composto, e, intermediário
AU2014326684A1 (en) * 2013-09-26 2016-03-24 The University Of Melbourne Bis-organometallic 2-amino-3-hydroxy-2-methylpropanenitrile derivatives for use as anthelmintics
BR112016006494A2 (pt) * 2013-09-26 2017-08-01 Univ Melbourne composto
KR102271848B1 (ko) * 2013-11-01 2021-07-01 피트니 파마슈티컬스 피티와이 리미티드 암 치료용 약학적 배합물
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
JPWO2021177334A1 (de) * 2020-03-04 2021-09-10

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FR1441499A (fr) * 1964-02-14 1966-06-10 Geigy Ag J R Nouveaux esters phényliques doués de propriétés antimicrobiennes, utilisables en particulier pour la protection des matériaux organiques
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KR100850252B1 (ko) * 2000-12-20 2008-08-04 노파르티스 아게 유기 화합물
AR035531A1 (es) 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
EP1390344B1 (de) * 2001-05-15 2006-12-27 Novartis AG Benzamidoacetonitrilderivate und ihre verwendung als antiparasitika
AR036054A1 (es) * 2001-06-15 2004-08-04 Novartis Ag Uso de compuestos de aminoacetonitrilo para el control de plagas, una composicion y un proceso para dicho control y una composicion farmaceutica contra parasitos
WO2003004474A1 (en) 2001-07-06 2003-01-16 Syngenta Participations Ag Pesticidally active aminoacetonitriles
CN1545500A (zh) * 2001-10-04 2004-11-10 诺瓦提斯公司 作为抗寄生虫剂的羰氧基-氰基甲基化合物
BR0213066A (pt) * 2001-10-04 2004-09-28 Novartis Ag Compostos de cianoacetila
TW200300140A (en) * 2001-11-14 2003-05-16 Novartis Ag Organic compounds
TWI261053B (en) * 2001-12-06 2006-09-01 Novartis Ag Amidoacetonitrile compounds, their preparation, compositions and use as pesticides
AR038156A1 (es) 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica
AR040082A1 (es) 2002-05-22 2005-03-16 Novartis Ag Derivados de n-acilaminoacetonitrilo y su uso para el control de parasitos
TW200400931A (en) * 2002-05-22 2004-01-16 Novartis Ag Organic compounds
AR039961A1 (es) * 2002-06-06 2005-03-09 Novartis Ag Derivados de amidoacetonitrilo y su uso como pesticida
AR040149A1 (es) * 2002-06-07 2005-03-16 Novartis Ag Compuestos de aminoacetonitrilo, un proceso para su preparacion, composicion, y uso del compuesto
TW200400932A (en) 2002-06-19 2004-01-16 Novartis Ag Organic compounds
GB0214117D0 (en) * 2002-06-19 2002-07-31 Syngenta Participations Ag N-sulphonylaminoacetonitriles having pesticidal properties
AR042420A1 (es) * 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) * 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas
TW200613251A (en) * 2004-06-10 2006-05-01 Novartis Ag Organic compounds
AR051761A1 (es) 2004-11-09 2007-02-07 Novartis Ag Compuestos organicos

Also Published As

Publication number Publication date
PL1682493T3 (pl) 2009-06-30
KR20060088122A (ko) 2006-08-03
DE602004018967D1 (de) 2009-02-26
JP2007510632A (ja) 2007-04-26
US7964635B2 (en) 2011-06-21
RU2006119506A (ru) 2007-12-27
CN100447130C (zh) 2008-12-31
US20070072944A1 (en) 2007-03-29
KR100793462B1 (ko) 2008-01-14
TWI342875B (en) 2011-06-01
US7494956B2 (en) 2009-02-24
BRPI0416294B1 (pt) 2018-06-05
DK1682493T3 (da) 2009-04-20
RU2370485C2 (ru) 2009-10-20
AU2004287611A1 (en) 2005-05-19
JP4319680B2 (ja) 2009-08-26
AU2004287611B2 (en) 2008-05-15
PT1682493E (pt) 2009-02-12
BRPI0416294A (pt) 2007-01-23
EP1682493A1 (de) 2006-07-26
EP1682493B8 (de) 2009-11-25
SI1682493T1 (sl) 2009-06-30
MXPA06005036A (es) 2006-07-06
TW200528024A (en) 2005-09-01
CA2544741A1 (en) 2005-05-19
GB0402677D0 (en) 2004-03-10
AR046322A1 (es) 2005-11-30
CA2544741C (en) 2012-08-07
ES2317070T3 (es) 2009-04-16
EP1682493B1 (de) 2009-01-07
US20090176868A1 (en) 2009-07-09
CN1902162A (zh) 2007-01-24
NZ546830A (en) 2009-07-31
WO2005044784A1 (en) 2005-05-19

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