DE60118231T2 - Verfahren zur reinigung von alpha-hydroxysäuren auf industrieller basis - Google Patents

Verfahren zur reinigung von alpha-hydroxysäuren auf industrieller basis Download PDF

Info

Publication number
DE60118231T2
DE60118231T2 DE60118231T DE60118231T DE60118231T2 DE 60118231 T2 DE60118231 T2 DE 60118231T2 DE 60118231 T DE60118231 T DE 60118231T DE 60118231 T DE60118231 T DE 60118231T DE 60118231 T2 DE60118231 T2 DE 60118231T2
Authority
DE
Germany
Prior art keywords
lactic acid
acid
hydroxy acid
crystallization
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60118231T
Other languages
German (de)
English (en)
Other versions
DE60118231D1 (de
Inventor
Jan Van Krieken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purac Biochem BV
Original Assignee
Purac Biochem BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purac Biochem BV filed Critical Purac Biochem BV
Application granted granted Critical
Publication of DE60118231D1 publication Critical patent/DE60118231D1/de
Publication of DE60118231T2 publication Critical patent/DE60118231T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60118231T 2000-09-15 2001-09-14 Verfahren zur reinigung von alpha-hydroxysäuren auf industrieller basis Expired - Lifetime DE60118231T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL1016203 2000-09-15
NL1016203 2000-09-15
PCT/NL2001/000682 WO2002022544A1 (en) 2000-09-15 2001-09-14 Method for the purification of α-hydroxy acids on an industrial scale

Publications (2)

Publication Number Publication Date
DE60118231D1 DE60118231D1 (de) 2006-05-11
DE60118231T2 true DE60118231T2 (de) 2006-12-28

Family

ID=19772099

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118231T Expired - Lifetime DE60118231T2 (de) 2000-09-15 2001-09-14 Verfahren zur reinigung von alpha-hydroxysäuren auf industrieller basis

Country Status (10)

Country Link
US (1) US7223885B2 (es)
EP (1) EP1317407B1 (es)
JP (2) JP4895337B2 (es)
CN (1) CN1294112C (es)
AT (1) ATE321018T1 (es)
AU (1) AU2002211056A1 (es)
BR (1) BR0113940B1 (es)
DE (1) DE60118231T2 (es)
ES (1) ES2260297T3 (es)
WO (1) WO2002022544A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2260297T3 (es) 2000-09-15 2006-11-01 Purac Biochem B.V. Metodo para la purificacion de alfa-hidroxiacidos a escala industrial.
JP5280007B2 (ja) * 2006-08-02 2013-09-04 株式会社クレハ ヒドロキシカルボン酸の精製方法、環状エステルの製造方法およびポリヒドロキシカルボン酸の製造方法
US7439391B2 (en) * 2006-10-12 2008-10-21 E.I. Du Pont De Nemours And Company Multi-stage glycolic acid crystallization
BE1018561A3 (fr) 2008-12-24 2011-03-01 Galactic Sa Procede de purification de l'acide lactique par cristallisation.
PL2275399T3 (pl) * 2009-07-16 2014-01-31 Purac Biochem Bv Ciekła kompozycja kwasu mlekowego i sposób jej otrzymywania
US8466328B2 (en) 2010-08-18 2013-06-18 Eastman Chemical Company Method for recovery and recycle of ruthenium homogeneous catalysts
US8829248B2 (en) 2010-08-18 2014-09-09 Eastman Chemical Company Method for recovery and recycle of ruthenium homogeneous catalysts
US9227896B2 (en) 2010-08-18 2016-01-05 Eastman Chemical Company Process for the separation and purification of a mixed diol stream
US8785686B2 (en) 2010-09-23 2014-07-22 Eastman Chemical Company Process for recovering and recycling an acid catalyst
US8709376B2 (en) 2010-09-23 2014-04-29 Eastman Chemical Company Process for recovering and recycling an acid catalyst
CN102531883B (zh) * 2010-12-28 2014-03-26 中国科学院大连化学物理研究所 一种连续生产乙醇酸的方法
FR2974804B1 (fr) 2011-05-06 2013-05-03 Roquette Freres Procede de preparation d'un acide glycolique de haute purete
US8927766B2 (en) 2012-03-27 2015-01-06 Eastman Chemical Company Hydrocarboxylation of methylene dipropionate in the presence of a propionic acid and a homogeneous catalyst
US8703999B2 (en) 2012-03-27 2014-04-22 Eastman Chemical Company Hydrocarboxylation of methylene dipropionate in the presence of propionic acid and a heterogeneous catalyst
US8829234B2 (en) 2012-03-27 2014-09-09 Eastman Chemical Company Hydrocarboxylation of formaldehyde in the presence of a higher order carboxylic acid and heterogeneous catalyst
US8765999B2 (en) 2012-03-27 2014-07-01 Eastman Chemical Company Hydrocarboxylation of formaldehyde in the presence of a higher order carboxylic acid and a homogeneous catalyst
US9040748B2 (en) 2012-06-08 2015-05-26 Eastman Chemical Company Hydrocarboxylation of aqueous formaldehyde using a dehydrating recycle stream to decrease water concentration
CN102992990B (zh) * 2012-10-15 2014-06-18 常州协丰医药研发有限公司 一种光学纯手性α-羟基烷基羧酸的制备方法
CN103694108B (zh) * 2013-12-17 2015-10-28 河南金丹乳酸科技股份有限公司 利用晶体乳酸连续生产液体乳酸的设备和方法
CN107771214B (zh) 2015-04-07 2022-01-18 代谢探索者公司 用于具有增加的2,4-二羟基丁酸外排物的优化的2,4-二羟基丁酸产生的修饰的微生物
US10415062B2 (en) 2015-04-07 2019-09-17 Metabolic Explorer Modified microorganism for the optimized production of 2,4-dihydroxybutyrate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE593657C (de) 1931-07-16 1934-03-01 Byk Guldenwerke Chem Fab Akt G Verfahren zur Herstellung von fester Milchsaeure
JPS50116461A (es) * 1974-03-01 1975-09-11
JPH0454152A (ja) * 1990-06-20 1992-02-21 Sumikin Chem Co Ltd ナフタレンカルボン酸エステルの精製方法
WO1992005138A1 (en) 1990-09-20 1992-04-02 E.I. Du Pont De Nemours And Company Manufacture of high-purity hydroxyacetic acid
JPH0578277A (ja) * 1991-03-04 1993-03-30 Nikko Kyodo Co Ltd ３，３，３−トリフルオロ乳酸の製造方法及び光学純度の向上法
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
DE19632924A1 (de) 1996-08-16 1998-02-19 Bayer Ag Verfahren zur Isolierung von Hydroxypivalinsäure aus wäßriger Lösung
BE1011197A3 (fr) * 1997-06-06 1999-06-01 Brussels Biotech En Abrege Bb Procede de purification d'acide lactique.
CN1083826C (zh) * 1999-01-22 2002-05-01 梁宇 一步法乳酸提纯工艺制备高纯耐热乳酸的方法及其设备
ES2225112T3 (es) * 1999-03-22 2005-03-16 Purac Biochem Bv Procedimiento de purificacion de acido lactico a escala industrial.
ES2260297T3 (es) 2000-09-15 2006-11-01 Purac Biochem B.V. Metodo para la purificacion de alfa-hidroxiacidos a escala industrial.

Also Published As

Publication number Publication date
CN1630628A (zh) 2005-06-22
JP5595336B2 (ja) 2014-09-24
JP4895337B2 (ja) 2012-03-14
BR0113940A (pt) 2003-07-22
US20040249206A1 (en) 2004-12-09
WO2002022544A1 (en) 2002-03-21
JP2004509090A (ja) 2004-03-25
US7223885B2 (en) 2007-05-29
EP1317407B1 (en) 2006-03-22
CN1294112C (zh) 2007-01-10
BR0113940B1 (pt) 2012-05-02
JP2011201917A (ja) 2011-10-13
EP1317407A1 (en) 2003-06-11
ES2260297T3 (es) 2006-11-01
DE60118231D1 (de) 2006-05-11
ATE321018T1 (de) 2006-04-15
AU2002211056A1 (en) 2002-03-26

Similar Documents

Publication Publication Date Title
DE60118231T2 (de) Verfahren zur reinigung von alpha-hydroxysäuren auf industrieller basis
DE60014047T2 (de) Verfahren zur reinigung von milchsäure auf industrieller basis
DE4404838B4 (de) Reinigung von Lactiden durch Schmelz-Kristallisation
EP2195441B1 (de) Gewinnung von Milchsäure durch Fermentation und Extraktion mit alkylierten Aminen
WO2016008745A1 (de) Verfahren und vorrichtung zur aufkonzentration und kristallisation von fermentierbaren carbonsäuren
DE60127144T2 (de) VERFAHREN ZUR REINIGUNG VON MILCHSÄURE IN INDUSTRIELLEM MAßSTAB
DE102008040193A1 (de) Verfahren zur Herstellung freier Carbonsäuren
DE69119234T2 (de) Verfahren zur herstellung von reiner hydroxyessigsäure
DE60111371T2 (de) Verfahren zur reinigung von zyklischen estern
DE3888236T2 (de) Methode zur Kristallisation der Fruktose.
DE60133013T2 (de) Verfahren zur reinigung von einer alpha-hydroxysäure auf industrieller basis
DE60104481T2 (de) Herstellung von Milchsäure durch Verdampfungs-Kristallisationsverfahren
DE939107C (de) Verfahren zur Chemikalienrueckgewinnung aus waessrigen, Kaliumacetat und Essigsaeure enthaltenden, verbrauchten Spinnbaedern, wie sie bei der Kunstseidenherstellung nach dem Nassspinnverfahren von Celluloseacetat anfallen
DE2213730C3 (es)
DE69905793T2 (de) Verfahren zur Herstellung von Kristallin-Maltulose-Monohydrat
DE2109456C3 (de) Verfahren zur Abtrennung von optisch reinem d- und I-Menthol
DE2109456B2 (de) Verfahren zur abtrennung von optisch reinem d- und l-menthol
DE2204771B2 (de) Verfahren zur Abtrennung von optisch reinem d- und 1-Neo- oder Isomenthol
DD246121A1 (de) Verfahren zur gewinnung von laktose
DE1593817B2 (de) Verfahren zur optischen aufspaltung von calciumpantothenat

Legal Events

Date Code Title Description
8364 No opposition during term of opposition