DE69628424D1 - Verfahren zur herstellung von nukleosid-analogen - Google Patents

Verfahren zur herstellung von nukleosid-analogen

Info

Publication number
DE69628424D1
DE69628424D1 DE69628424T DE69628424T DE69628424D1 DE 69628424 D1 DE69628424 D1 DE 69628424D1 DE 69628424 T DE69628424 T DE 69628424T DE 69628424 T DE69628424 T DE 69628424T DE 69628424 D1 DE69628424 D1 DE 69628424D1
Authority
DE
Germany
Prior art keywords
nucleoside analogs
producing nucleoside
producing
intermediates
ethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69628424T
Other languages
English (en)
Other versions
DE69628424T2 (de
Inventor
C Samano
Vicente Samano
David Goodyear
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10772237&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69628424(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE69628424D1 publication Critical patent/DE69628424D1/de
Application granted granted Critical
Publication of DE69628424T2 publication Critical patent/DE69628424T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE69628424T 1995-03-31 1996-03-26 Verfahren zur herstellung von nukleosid-analogen Expired - Lifetime DE69628424T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9506644.5A GB9506644D0 (en) 1995-03-31 1995-03-31 Preparation of nucleoside analogues
GB9506644 1995-03-31
PCT/EP1996/001353 WO1996030369A1 (en) 1995-03-31 1996-03-26 Process for the synthesis of nucleoside analogues

Publications (2)

Publication Number Publication Date
DE69628424D1 true DE69628424D1 (de) 2003-07-03
DE69628424T2 DE69628424T2 (de) 2004-03-18

Family

ID=10772237

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69628424T Expired - Lifetime DE69628424T2 (de) 1995-03-31 1996-03-26 Verfahren zur herstellung von nukleosid-analogen

Country Status (17)

Country Link
US (2) US6143748A (de)
EP (1) EP0817784B1 (de)
JP (1) JP4173195B2 (de)
CN (2) CN1290845C (de)
AT (1) ATE241619T1 (de)
AU (1) AU5497396A (de)
BR (2) BR9607850B1 (de)
DE (1) DE69628424T2 (de)
DK (1) DK0817784T3 (de)
ES (1) ES2200060T3 (de)
GB (1) GB9506644D0 (de)
HK (1) HK1009451A1 (de)
HU (1) HU223100B1 (de)
NO (1) NO316174B1 (de)
PL (1) PL188693B1 (de)
PT (1) PT817784E (de)
WO (1) WO1996030369A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506644D0 (en) * 1995-03-31 1995-05-24 Wellcome Found Preparation of nucleoside analogues
KR100856416B1 (ko) 1998-08-12 2008-09-04 길리애드 사이언시즈, 인코포레이티드 1,3-옥사티올란 뉴클레오시드의 제조 방법
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
CN110156699A (zh) * 2019-05-22 2019-08-23 南京合巨药业有限公司 一种4-乙氧基-1h-嘧啶-2-酮的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
ZA923640B (en) * 1991-05-21 1993-02-24 Iaf Biochem Int Processes for the diastereoselective synthesis of nucleosides
GB9116601D0 (en) * 1991-08-01 1991-09-18 Iaf Biochem Int 1,3-oxathiolane nucleoside analogues
JP3499896B2 (ja) * 1993-03-12 2004-02-23 財団法人野口研究所 2’−デオキシヌクレオシド類の製造方法
IL113432A (en) * 1994-04-23 2000-11-21 Glaxo Group Ltd Process for the diastereoselective synthesis of nucleoside analogues
GB9506644D0 (en) * 1995-03-31 1995-05-24 Wellcome Found Preparation of nucleoside analogues

Also Published As

Publication number Publication date
WO1996030369A1 (en) 1996-10-03
BR9607850A (pt) 1998-07-14
NO974512L (no) 1997-09-29
BRPI9607850B8 (pt) 2019-11-05
HK1009451A1 (en) 1999-09-10
PT817784E (pt) 2003-10-31
US6066733A (en) 2000-05-23
DE69628424T2 (de) 2004-03-18
PL188693B1 (pl) 2005-03-31
NO974512D0 (no) 1997-09-29
DK0817784T3 (da) 2003-09-08
JPH11502826A (ja) 1999-03-09
ES2200060T3 (es) 2004-03-01
CN1180356A (zh) 1998-04-29
GB9506644D0 (en) 1995-05-24
US6143748A (en) 2000-11-07
HUP9801576A3 (en) 2000-07-28
HUP9801576A2 (hu) 1999-05-28
NO316174B1 (no) 2003-12-22
HU223100B1 (hu) 2004-03-29
JP4173195B2 (ja) 2008-10-29
AU5497396A (en) 1996-10-16
EP0817784B1 (de) 2003-05-28
CN1995022A (zh) 2007-07-11
CN1995022B (zh) 2013-01-02
ATE241619T1 (de) 2003-06-15
PL322503A1 (en) 1998-02-02
CN1290845C (zh) 2006-12-20
BR9607850B1 (pt) 2010-11-30
EP0817784A1 (de) 1998-01-14

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