DE60042342D1 - - Google Patents
Info
- Publication number
- DE60042342D1 DE60042342D1 DE60042342T DE60042342T DE60042342D1 DE 60042342 D1 DE60042342 D1 DE 60042342D1 DE 60042342 T DE60042342 T DE 60042342T DE 60042342 T DE60042342 T DE 60042342T DE 60042342 D1 DE60042342 D1 DE 60042342D1
- Authority
- DE
- Germany
- Prior art keywords
- methods
- human
- hama
- antibodies
- samples
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/809—Multifield plates or multicontainer arrays
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/456,090 US6680209B1 (en) | 1999-12-06 | 1999-12-06 | Human antibodies as diagnostic reagents |
PCT/US2000/033042 WO2001040306A1 (en) | 1999-12-06 | 2000-12-06 | Human antibodies as detection reagents |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60042342D1 true DE60042342D1 (de) | 2009-07-16 |
Family
ID=23811375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60042342T Revoked DE60042342D1 (de) | 1999-12-06 | 2000-12-06 |
Country Status (9)
Country | Link |
---|---|
US (3) | US6680209B1 (de) |
EP (1) | EP1237926B1 (de) |
JP (1) | JP2003530543A (de) |
AT (1) | ATE432947T1 (de) |
AU (1) | AU781736B2 (de) |
CA (1) | CA2392729A1 (de) |
DE (1) | DE60042342D1 (de) |
GB (1) | GB2374415B (de) |
WO (1) | WO2001040306A1 (de) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040191260A1 (en) * | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
US20060062786A1 (en) * | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
CN100497389C (zh) * | 2001-06-13 | 2009-06-10 | 根马布股份公司 | 表皮生长因子受体(egfr)的人单克隆抗体 |
US7595378B2 (en) | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
US7084257B2 (en) | 2001-10-05 | 2006-08-01 | Amgen Inc. | Fully human antibody Fab fragments with human interferon-gamma neutralizing activity |
CA2463931A1 (en) * | 2001-10-16 | 2003-04-24 | The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services | Broadly cross-reactive neutralizing antibodies against human immunodeficiency virus selected by env-cd4-co-receptor complexes |
US6992176B2 (en) * | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
JP2005533486A (ja) * | 2002-02-20 | 2005-11-10 | ダイアックス、コープ | Mhc−ペプチド複合体結合リガンド |
EP1504034B1 (de) * | 2002-05-06 | 2012-12-12 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Identifikation neuer breitkreuzreaktiver hiv-1-neutralisierender humaner monoklonaler antikörper |
CA2484930A1 (en) * | 2002-05-06 | 2003-11-13 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Identification of novel broadly cross-reactive neutralizing human monoclonal antibodies using sequential antigen panning of phage display libraries |
US7108993B2 (en) * | 2002-07-19 | 2006-09-19 | Bayer Healthcare Llc | Use of dual conjugated labels in the elimination of serum interference in immunochromatographic assays |
CA2496741A1 (en) * | 2002-08-28 | 2004-04-29 | Bionexus Ventures L.L.C. | Screening compound libraries using an optical fiber array device capable of simultaneously performing multiple functional assays |
EP1590364B1 (de) * | 2002-12-16 | 2011-10-05 | Genmab A/S | Humane monoklonale antikörper gegen interleukin 8 (il-8) |
WO2005011619A2 (en) * | 2003-01-31 | 2005-02-10 | Five Prime Therapeutics, Inc. | Lung-expressed polypeptides |
RS54160B1 (sr) | 2003-03-19 | 2015-12-31 | Biogen Idec Ma Inc. | Protein koji se vezuje za nogo receptor |
AR045563A1 (es) * | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
CA2572193A1 (en) | 2004-06-24 | 2006-01-05 | Biogen Idec Ma Inc. | Treatment of conditions involving oligodendrocytes with sp35 based agents |
TWI380996B (zh) * | 2004-09-17 | 2013-01-01 | Hoffmann La Roche | 抗ox40l抗體 |
WO2006044410A2 (en) * | 2004-10-14 | 2006-04-27 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | A32 monoclonal antibody fusion proteins for use as hiv inhibitors and vaccines |
US20070292390A1 (en) * | 2004-10-29 | 2007-12-20 | Dimitrov Dimiter S | Broadly Cross-Reactive Hiv-1 Neutralizing Human Monoclonal Antibodies |
EP1817341A2 (de) * | 2004-11-29 | 2007-08-15 | Seattle Genetics, Inc. | Veränderte antikörper und immunkonjugate |
US7396689B2 (en) * | 2005-02-04 | 2008-07-08 | Decision Biomarkers Incorporated | Method of adjusting the working range of a multi-analyte assay |
CA2605964A1 (en) | 2005-04-20 | 2006-10-26 | Amgen Fremont Inc. | High affinity fully human monoclonal antibodies to interleukin-8 and epitopes for such antibodies |
EP2238986A3 (de) | 2005-07-08 | 2010-11-03 | Biogen Idec MA Inc. | Sp35-Antikörper und Verwendungen dafür |
WO2007084321A2 (en) | 2006-01-12 | 2007-07-26 | Alexion Pharmaceuticals, Inc. | Antibodies to ox-2/cd200 and uses thereof |
EP1918302A3 (de) * | 2006-05-18 | 2009-11-18 | AvantGen, Inc. | Verfahren zur Identifikation und Isolation von epitopspezifischen Antikörpern |
CA2652538C (en) * | 2006-05-19 | 2016-06-28 | Teva Pharmaceutical Industries, Ltd. | Fusion proteins, uses thereof and processes for producing same |
US8128926B2 (en) | 2007-01-09 | 2012-03-06 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
JP5553615B2 (ja) * | 2007-03-01 | 2014-07-16 | アボット・ラボラトリーズ | プロゾーン現象の低減を示すイムノアッセイ |
SI2125894T1 (sl) | 2007-03-22 | 2019-05-31 | Biogen Ma Inc. | Vezavne beljakovine, vključno s protitelesi, derivati protiteles in fragmenti protiteles, ki specifično vežejo CD154, ter njihove uporabe |
US20100291024A1 (en) * | 2007-03-30 | 2010-11-18 | Xuebin Qin | Methods and compositions for the treatment of proliferative and pathogenic diseases |
WO2008154927A1 (en) * | 2007-06-21 | 2008-12-24 | Genmab A/S | Novel methods for treating egfr-associated tumors |
CN101980603A (zh) * | 2007-10-11 | 2011-02-23 | 比奥根艾迪克Ma公司 | LINGO-1和TrkB拮抗剂的用途 |
CN101918540B (zh) * | 2007-11-08 | 2016-05-11 | 比奥根Ma公司 | Lingo-4拮抗剂在治疗涉及脱髓鞘的疾患中的应用 |
US20090203038A1 (en) * | 2007-12-27 | 2009-08-13 | Abbott Laboratories | Negative Mimic Antibody For Use as a Blocking Reagent In BNP Immunoassays |
JP2009184981A (ja) * | 2008-02-07 | 2009-08-20 | Shiseido Co Ltd | 抗d−アミノ酸モノクローナル抗体及び、抗d−アミノ酸モノクローナル抗体を用いたd−アミノ酸の免疫学的分析方法 |
WO2009125394A1 (en) * | 2008-04-09 | 2009-10-15 | Technion Research & Development Foundation Ltd. | Anti human immunodeficiency antibodies and uses thereof |
EP2297200A1 (de) * | 2008-04-09 | 2011-03-23 | Technion Research & Development Foundation Ltd. | Anti-influenza-antikörper und anwendungen davon |
WO2009125381A1 (en) * | 2008-04-10 | 2009-10-15 | Objet Geometries Ltd. | System and method for three dimensional model printing |
SE533515C2 (sv) | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
EP2309264A4 (de) * | 2008-06-06 | 2011-11-23 | Univ Toyama Nat Univ Corp | Grippevirusnachweisvorrichtung |
AU2009269099B2 (en) | 2008-07-09 | 2016-03-10 | Biogen Ma Inc. | Compositions comprising antibodies to LINGO or fragments thereof |
AU2009313203B2 (en) | 2008-11-10 | 2015-08-27 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating complement-associated disorders |
WO2011022472A2 (en) * | 2009-08-18 | 2011-02-24 | President And Fellows Of Harvard College | Methods and compositions for the treatment of proliferative and pathogenic diseases |
WO2011036555A1 (en) | 2009-09-25 | 2011-03-31 | University Of Oslo | Multivalent phage display systems and methods |
RU2571489C2 (ru) | 2009-10-26 | 2015-12-20 | Нестек С.А. | Способы выявления препаратов и аутоантител против tnf |
EP2523976B1 (de) | 2010-01-11 | 2018-04-25 | Alexion Pharmaceuticals, Inc. | Biomarker für immunmodulatorische effekte bei mit antikörpern gegen cd200 behandelten patienten |
SG185383A1 (en) | 2010-04-30 | 2012-12-28 | Alexion Pharma Inc | Anti-c5a antibodies and methods for using the antibodies |
KR20130036276A (ko) | 2010-06-22 | 2013-04-11 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 보체 결합 3의 C3d 조각에 대한 항체들 |
BR112013009376A2 (pt) | 2010-10-18 | 2016-07-26 | Nestec Sa | métodos para determinar isótipos de anticorpos antifármacos |
US9447187B2 (en) | 2011-02-03 | 2016-09-20 | Alexion Pharmaceuticals, Inc. | Use of an anti-CD200 antibody for prolonging the survival of allografts |
US9726666B2 (en) | 2011-06-13 | 2017-08-08 | Tla Targeted Immunotherapies Ab | Diagnosing and treating inflammatory diseases |
DK3228631T3 (da) * | 2011-06-13 | 2020-09-28 | Tla Targeted Immunotherapies Ab | Behandling af respiratoriske tilstande |
MX343324B (es) | 2011-07-06 | 2016-11-01 | Nestec Sa | Ensayos para detectar auto anticuerpos neutralizadores de la terapia biologica con tnf alpha. |
US9220733B2 (en) | 2012-03-19 | 2015-12-29 | The Regents Of The University Of California | Solubilization of antigen components for removal from tissues |
JP2015518829A (ja) | 2012-05-14 | 2015-07-06 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | 運動ニューロンに関する状態の処置のためのlingo−2アンタゴニスト |
WO2014085687A1 (en) | 2012-11-28 | 2014-06-05 | Abwiz Bio, Inc. | Preparation of gene-specific templates for the use in single primer amplification |
US20140212987A1 (en) * | 2013-01-30 | 2014-07-31 | Siemens Healthcare Diagnostics Inc. | Signal Ratio in Assay Calibrators |
EP3004882B1 (de) * | 2013-06-06 | 2018-03-21 | Koninklijke Philips N.V. | Reagenzien, verfahren und vorrichtungen zur verhinderung der aggregation bei partikelbasierten tests für den nachweis von multimeren zielmolekülen |
BR112017011545A2 (pt) | 2014-12-05 | 2018-03-13 | Nestec Sa | ensaio de desvio de mobilidade homogênea indireto para a detecção de produtos biológicos nas amostras do paciente |
CA2973266A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
CN108064241A (zh) * | 2015-04-17 | 2018-05-22 | 阿尔萨尼斯生物科学有限责任公司 | 针对金黄色葡萄球菌的免疫球蛋白结合蛋白的抗体 |
US11899020B2 (en) | 2017-03-31 | 2024-02-13 | The Regents Of The University Of California | Shotgun proteomic antigen identification |
BR112020013144A2 (pt) | 2018-01-12 | 2020-12-08 | Bristol-Myers Squibb Company | Terapia de combinação com anticorpos anti-il-8 e anti-corpos anti-pd-1 para tratamento do câncer |
BR112021022405A2 (pt) * | 2019-05-09 | 2022-04-19 | Merus Nv | Domínios variantes para multimerização de proteínas e separação das mesmas |
WO2021154993A1 (en) * | 2020-01-28 | 2021-08-05 | University Of Southern California | Genome engineering the human immunoglobulin locus to express recombinant binding domain molecules |
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US3654090A (en) * | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
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US4514505A (en) * | 1982-05-21 | 1985-04-30 | The Trustees Of Columbia University In The City Of New York | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays |
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US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
DK169582B1 (da) | 1986-06-23 | 1994-12-12 | Squibb Bristol Myers Co | Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant |
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-
1999
- 1999-12-06 US US09/456,090 patent/US6680209B1/en not_active Expired - Lifetime
-
2000
- 2000-12-06 JP JP2001541060A patent/JP2003530543A/ja active Pending
- 2000-12-06 CA CA002392729A patent/CA2392729A1/en not_active Abandoned
- 2000-12-06 WO PCT/US2000/033042 patent/WO2001040306A1/en active IP Right Grant
- 2000-12-06 AU AU20630/01A patent/AU781736B2/en not_active Ceased
- 2000-12-06 US US10/149,737 patent/US7189515B2/en not_active Expired - Lifetime
- 2000-12-06 DE DE60042342T patent/DE60042342D1/de not_active Revoked
- 2000-12-06 GB GB0215302A patent/GB2374415B/en not_active Expired - Lifetime
- 2000-12-06 AT AT00983939T patent/ATE432947T1/de not_active IP Right Cessation
- 2000-12-06 EP EP00983939A patent/EP1237926B1/de not_active Revoked
-
2007
- 2007-03-12 US US11/685,068 patent/US20080039338A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GB2374415B (en) | 2004-12-29 |
WO2001040306A1 (en) | 2001-06-07 |
US20080039338A1 (en) | 2008-02-14 |
GB0215302D0 (en) | 2002-08-14 |
CA2392729A1 (en) | 2001-06-07 |
GB2374415A (en) | 2002-10-16 |
US7189515B2 (en) | 2007-03-13 |
US6680209B1 (en) | 2004-01-20 |
EP1237926A1 (de) | 2002-09-11 |
EP1237926A4 (de) | 2006-04-12 |
US20030165993A1 (en) | 2003-09-04 |
WO2001040306A9 (en) | 2002-05-30 |
AU781736B2 (en) | 2005-06-09 |
EP1237926B1 (de) | 2009-06-03 |
AU2063001A (en) | 2001-06-12 |
ATE432947T1 (de) | 2009-06-15 |
JP2003530543A (ja) | 2003-10-14 |
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