AU2001250470A1 - Novel antibodies specifically identifying inactive psa, and uses thereof - Google Patents

Novel antibodies specifically identifying inactive psa, and uses thereof

Info

Publication number
AU2001250470A1
AU2001250470A1 AU2001250470A AU5047001A AU2001250470A1 AU 2001250470 A1 AU2001250470 A1 AU 2001250470A1 AU 2001250470 A AU2001250470 A AU 2001250470A AU 5047001 A AU5047001 A AU 5047001A AU 2001250470 A1 AU2001250470 A1 AU 2001250470A1
Authority
AU
Australia
Prior art keywords
antibody
antibodies specifically
novel antibodies
specifically identifying
zymogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001250470A
Inventor
Jean-Philippe Charrier
Colette Jolivet-Reynaud
Sandrine Michel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Publication of AU2001250470A1 publication Critical patent/AU2001250470A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

An immunoassay for the quantitative determination of inactive, non-zymogen, free PSA in a biological sample taken from an individual, including contacting the biological sample with a reagent, where the reagent comprises an antibody or antibody fragments that bind specifically to inactive, non-zymogen, free PSA, the antibody being a purified polyclonal antibody or a monoclonal antibody, and evaluating the amount of inactive, non-zymogen, free PSA bound to the antibodies or antibody fragments.
AU2001250470A 2000-04-10 2001-04-10 Novel antibodies specifically identifying inactive psa, and uses thereof Abandoned AU2001250470A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0004591A FR2807438B1 (en) 2000-04-10 2000-04-10 NOVEL ANTIBODIES SPECIFICALLY RECOGNIZING INACTIVE FREE PSA AND THEIR APPLICATIONS
FR0004591 2000-04-10
PCT/FR2001/001094 WO2001077180A1 (en) 2000-04-10 2001-04-10 Novel antibodies specifically identifying inactive psa, and uses thereof

Publications (1)

Publication Number Publication Date
AU2001250470A1 true AU2001250470A1 (en) 2001-10-23

Family

ID=8849094

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001250470A Abandoned AU2001250470A1 (en) 2000-04-10 2001-04-10 Novel antibodies specifically identifying inactive psa, and uses thereof

Country Status (10)

Country Link
US (2) US20030153017A1 (en)
EP (1) EP1272525B1 (en)
AT (1) ATE336513T1 (en)
AU (1) AU2001250470A1 (en)
CA (1) CA2405637A1 (en)
DE (1) DE60122306T2 (en)
ES (1) ES2269376T3 (en)
FR (1) FR2807438B1 (en)
PT (1) PT1272525E (en)
WO (1) WO2001077180A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0325483D0 (en) * 2003-10-31 2003-12-03 Plasmacute As Assay
CN1926433A (en) * 2004-03-03 2007-03-07 拜奥默里克斯公司 Method for detecting the activatable free form of PSA and the use thereof for diagnosing benign pathologies of the prostate and adenocarcinoma of the prostate
DE102007028659A1 (en) * 2007-06-21 2008-12-24 Siemens Ag Diagnostic substance and method for the diagnosis of prostate diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002480D0 (en) * 1990-07-23 1990-07-23 Hans Lilja ASSAY OF FREE AND COMPLEXED PROSTATE-SPECIFIC ANTIGEN
EP0635575A1 (en) * 1993-07-22 1995-01-25 Wallac Oy Monoclonal antibodies against epitopes found in free but not in alpha-1-antichmotrypsin complexed prostate specific antigen
JP5284554B2 (en) * 1997-04-30 2013-09-11 ハイブリテック インコーポレイテッド Prostate-specific antigen morphology and detection method thereof
US5994085A (en) * 1997-08-26 1999-11-30 Cantor; Thomas L. Methods and devices for detecting non-complexed prostate specific antigen
FR2780791B1 (en) * 1998-07-03 2000-09-01 Bio Merieux METHOD OF SCREENING OR DIAGNOSIS OF ADENOCARCINOMA OR BENIGN PROSTATE PATHOLOGY AND PROCESS FOR IMPLEMENTATION
US6482599B1 (en) * 1999-04-30 2002-11-19 Hybritech Incorporated Forms of prostate specific antigen (PSA) specific for benign prostatic hyperplasia (BPH) and methods of using such

Also Published As

Publication number Publication date
FR2807438A1 (en) 2001-10-12
US20030153017A1 (en) 2003-08-14
US20070020710A1 (en) 2007-01-25
EP1272525B1 (en) 2006-08-16
ES2269376T3 (en) 2007-04-01
FR2807438B1 (en) 2004-09-17
DE60122306D1 (en) 2006-09-28
CA2405637A1 (en) 2001-10-18
DE60122306T2 (en) 2007-08-30
ATE336513T1 (en) 2006-09-15
WO2001077180A1 (en) 2001-10-18
PT1272525E (en) 2006-12-29
EP1272525A1 (en) 2003-01-08

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