DE3910578A1 - Mittel zur transdermalen applikation enthaltend gestoden - Google Patents

Mittel zur transdermalen applikation enthaltend gestoden

Info

Publication number
DE3910578A1
DE3910578A1 DE19893910578 DE3910578A DE3910578A1 DE 3910578 A1 DE3910578 A1 DE 3910578A1 DE 19893910578 DE19893910578 DE 19893910578 DE 3910578 A DE3910578 A DE 3910578A DE 3910578 A1 DE3910578 A1 DE 3910578A1
Authority
DE
Germany
Prior art keywords
estrogen
penetration
layer
enhancing agents
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19893910578
Other languages
German (de)
English (en)
Inventor
Clemens Guenther
Ulrich Dr Taeuber
Karin Dr Schmidt-Gollwitzer
Jutta Dr Riedl
Johannes-Wilhelm Dr Tack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to DE19893910578 priority Critical patent/DE3910578A1/de
Priority to JP51155389A priority patent/JP3238389B2/ja
Priority to EP89118855A priority patent/EP0370220B1/de
Priority to DE58909570T priority patent/DE58909570D1/de
Priority to EP89912449A priority patent/EP0394429B1/de
Priority to EP93250189A priority patent/EP0573133A1/de
Priority to ES89118855T priority patent/ES2081823T3/es
Priority to HU896546A priority patent/HU210549B/hu
Priority to PCT/EP1989/001200 priority patent/WO1990004397A1/de
Priority to AT89912449T priority patent/ATE132751T1/de
Priority to MX017971A priority patent/MX173621B/es
Priority to IL9200789A priority patent/IL92007A/en
Priority to IE970562A priority patent/IE970562A1/en
Priority to IE337689A priority patent/IE81077B1/en
Priority to AU43747/89A priority patent/AU4374789A/en
Priority to CN89108149A priority patent/CN1036836C/zh
Priority to KR1019890015580A priority patent/KR0137463B1/ko
Priority to PL28203389A priority patent/PL162400B1/pl
Priority to CA002001618A priority patent/CA2001618C/en
Priority to PL28752689A priority patent/PL162410B1/pl
Priority to PT92131A priority patent/PT92131B/pt
Priority to SK608989A priority patent/SK608989A3/sk
Priority to CS896089A priority patent/CZ277870B6/cs
Priority to DK199001385A priority patent/DK175804B1/da
Priority to BG092281A priority patent/BG92281A/bg
Priority to NO902840A priority patent/NO180567C/no
Priority to FI903213A priority patent/FI100456B/fi
Priority to SU904830921A priority patent/RU2044541C1/ru
Publication of DE3910578A1 publication Critical patent/DE3910578A1/de
Priority to AU30011/92A priority patent/AU3001192A/en
Priority to US08/403,137 priority patent/US5788984A/en
Priority to NO951592A priority patent/NO951592D0/no
Priority to AU20596/95A priority patent/AU2059695A/en
Priority to GR960400488T priority patent/GR3019079T3/el
Priority to CN96109379A priority patent/CN1069829C/zh
Priority to AU77416/98A priority patent/AU714979B2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE19893910578 1988-10-27 1989-03-29 Mittel zur transdermalen applikation enthaltend gestoden Withdrawn DE3910578A1 (de)

Priority Applications (35)

Application Number Priority Date Filing Date Title
DE19893910578 DE3910578A1 (de) 1989-03-29 1989-03-29 Mittel zur transdermalen applikation enthaltend gestoden
JP51155389A JP3238389B2 (ja) 1988-10-27 1989-10-11 ゲストデン含有の経皮適用のための薬剤
EP89118855A EP0370220B1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen Applikation enthaltend Gestoden
DE58909570T DE58909570D1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen applikation enthaltend gestoden
EP89912449A EP0394429B1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen applikation enthaltend gestoden
EP93250189A EP0573133A1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen Applikation das Gestoden enthält
ES89118855T ES2081823T3 (es) 1988-10-27 1989-10-11 Agente para la aplicacion transdermica, que contiene gestoden.
HU896546A HU210549B (en) 1988-10-27 1989-10-11 Process for producing transdermally applicable pharmaceutical composition containing gestodene
PCT/EP1989/001200 WO1990004397A1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen applikation enthaltend gestoden
AT89912449T ATE132751T1 (de) 1988-10-27 1989-10-11 Mittel zur transdermalen applikation enthaltend gestoden
MX017971A MX173621B (es) 1988-10-27 1989-10-16 Agente para administracion transdermica que contiene gestodeno
IL9200789A IL92007A (en) 1988-10-27 1989-10-16 Healing and contraceptive preparations that are inserted through the skin and contain Gestudin
IE970562A IE970562A1 (pl) 1988-10-27 1989-10-20
IE337689A IE81077B1 (en) 1988-10-27 1989-10-20 Gestodene-containing agent for transdermal administration
AU43747/89A AU4374789A (en) 1988-10-27 1989-10-25 Gestodene-containing agent for transdermal administration
CN89108149A CN1036836C (zh) 1988-10-27 1989-10-25 制备含有孕二烯酮的透皮治疗***的方法
PL28203389A PL162400B1 (pl) 1989-03-29 1989-10-26 Sposób wytwarzania poprzezskórnego ukladu terapeutycznego PL
KR1019890015580A KR0137463B1 (ko) 1988-10-27 1989-10-26 게스토덴을 함유하는 경피 투여용 제제
CA002001618A CA2001618C (en) 1988-10-27 1989-10-26 Gestodene-containing agent for transdermal administration
PL28752689A PL162410B1 (pl) 1989-03-29 1989-10-26 Sposób wytwarzania poprzezskórnego ukladu terapeutycznegoNumer zgloszenia, z którego nastapilo wydzielenie:282033 PL
PT92131A PT92131B (pt) 1988-10-27 1989-10-27 Processo para a preparacao de meios para aplicacao transdermica contendo gestodeno
SK608989A SK608989A3 (en) 1989-03-29 1989-10-27 The composition for transdermal application with gestodene content
CS896089A CZ277870B6 (en) 1989-03-29 1989-10-27 Preparation containing gestoden for transdermal application
DK199001385A DK175804B1 (da) 1988-10-27 1990-06-06 Middel til transdermal applikation indeholdende gestoden
BG092281A BG92281A (bg) 1988-10-27 1990-06-21 Метод за получаване на трансдермални системи
SU904830921A RU2044541C1 (ru) 1989-03-29 1990-06-26 Способ получения лечебного средства для трансдермального применения
FI903213A FI100456B (fi) 1988-10-27 1990-06-26 Gestodeenia sisältävän vaikuttavan aineen transdermaaliseen antoon tar koitetun välineen käyttö raskauden ehkäisyyn
NO902840A NO180567C (no) 1988-10-27 1990-06-26 Befruktningshindrende og/eller syklusregulerende middel for transdermal applikasjon
AU30011/92A AU3001192A (en) 1988-10-27 1992-12-09 Gestodene-containing agent for transdermal administration
US08/403,137 US5788984A (en) 1988-10-27 1995-03-13 Gestodene-containing agent for transdermal administration
NO951592A NO951592D0 (no) 1988-10-27 1995-04-26 Fremgangsmåte for fremstilling av et transdermalt terapeutisk system
AU20596/95A AU2059695A (en) 1988-10-27 1995-06-08 Gestodene-containing agent for transdermal administration
GR960400488T GR3019079T3 (en) 1988-10-27 1996-02-22 Gestode composition for transdermal application
CN96109379A CN1069829C (zh) 1988-10-27 1996-07-30 含有孕二烯酮的透皮应用的药剂
AU77416/98A AU714979B2 (en) 1988-10-27 1998-07-21 Gestodene-containing agent for transdermal administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19893910578 DE3910578A1 (de) 1989-03-29 1989-03-29 Mittel zur transdermalen applikation enthaltend gestoden

Publications (1)

Publication Number Publication Date
DE3910578A1 true DE3910578A1 (de) 1990-10-04

Family

ID=6377622

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19893910578 Withdrawn DE3910578A1 (de) 1988-10-27 1989-03-29 Mittel zur transdermalen applikation enthaltend gestoden

Country Status (5)

Country Link
CZ (1) CZ277870B6 (pl)
DE (1) DE3910578A1 (pl)
PL (2) PL162410B1 (pl)
RU (1) RU2044541C1 (pl)
SK (1) SK608989A3 (pl)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018774A1 (de) * 1992-03-21 1993-09-30 Entec Gesellschaft Für Endokrinologische Technologie M.B.H. Verwendung von östriol zur behandlung von klimakterischer osteoporose
DE19526864A1 (de) * 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
DE10019171A1 (de) * 2000-04-07 2001-10-18 Schering Ag Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1195505C (zh) 1999-07-02 2005-04-06 Lts勒曼治疗***股份公司 以聚硅氧烷及亲两性溶剂为基础的微贮存***
WO2008136699A1 (fr) * 2007-05-04 2008-11-13 Igor Alexandrovich Bazikov Patch transdermique à microcapsules et procédé de fabrication correspondant

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018774A1 (de) * 1992-03-21 1993-09-30 Entec Gesellschaft Für Endokrinologische Technologie M.B.H. Verwendung von östriol zur behandlung von klimakterischer osteoporose
AU665997B2 (en) * 1992-03-21 1996-01-25 Entec Gesellschaft Fur Endokrinologische Technologie M.B.H. Use of estriol for treating climacteric osteoporosis
US5614213A (en) * 1992-03-21 1997-03-25 Entec Gesellschaft Fuer Endokrinologische Technologie M.B.H. Use of estriol for treatment of climacteric osteoporosis
DE19526864A1 (de) * 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
US5985311A (en) * 1995-07-22 1999-11-16 Labtec Gesellschaft Fuer Techologische Forschung Und Entwicklung Mbh Transdermal hormone patch
DE10019171A1 (de) * 2000-04-07 2001-10-18 Schering Ag Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe

Also Published As

Publication number Publication date
PL282033A1 (en) 1991-03-11
PL162410B1 (pl) 1993-11-30
SK278438B6 (en) 1997-05-07
PL287526A1 (en) 1991-10-21
CZ277870B6 (en) 1993-06-16
RU2044541C1 (ru) 1995-09-27
SK608989A3 (en) 1997-05-07
PL162400B1 (pl) 1993-11-30
CZ608989A3 (en) 1993-02-17

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: SCHERING AG, 13353 BERLIN, DE

8141 Disposal/no request for examination