DE3261256D1 - Process for the preparation of isosorbide mononitrates - Google Patents

Process for the preparation of isosorbide mononitrates

Info

Publication number
DE3261256D1
DE3261256D1 DE8282400328T DE3261256T DE3261256D1 DE 3261256 D1 DE3261256 D1 DE 3261256D1 DE 8282400328 T DE8282400328 T DE 8282400328T DE 3261256 T DE3261256 T DE 3261256T DE 3261256 D1 DE3261256 D1 DE 3261256D1
Authority
DE
Germany
Prior art keywords
solvent medium
preparation
isosorbide
hydrazine derivative
isosorbide mononitrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282400328T
Other languages
English (en)
Inventor
Jean-Marie Emeury
Eric Wimmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe Nationale des Poudres et Explosifs
Original Assignee
Societe Nationale des Poudres et Explosifs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Nationale des Poudres et Explosifs filed Critical Societe Nationale des Poudres et Explosifs
Application granted granted Critical
Publication of DE3261256D1 publication Critical patent/DE3261256D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8282400328T 1981-02-27 1982-02-25 Process for the preparation of isosorbide mononitrates Expired DE3261256D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8103906A FR2500835A1 (fr) 1981-02-27 1981-02-27 Procede de synthese des mononitrates d'isosorbide

Publications (1)

Publication Number Publication Date
DE3261256D1 true DE3261256D1 (en) 1985-01-03

Family

ID=9255675

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282400328T Expired DE3261256D1 (en) 1981-02-27 1982-02-25 Process for the preparation of isosorbide mononitrates

Country Status (11)

Country Link
US (1) US4381400A (de)
EP (1) EP0059664B1 (de)
JP (1) JPS57156492A (de)
AT (1) ATE10371T1 (de)
CA (1) CA1182829A (de)
DE (1) DE3261256D1 (de)
ES (1) ES8302716A1 (de)
FR (1) FR2500835A1 (de)
HU (1) HU191346B (de)
IE (1) IE52602B1 (de)
IN (1) IN157599B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3124410A1 (de) * 1981-06-22 1983-01-05 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-2-nitrat
JPS60149521A (ja) * 1984-01-18 1985-08-07 Eisai Co Ltd 高眼圧・緑内障治療・予防用点眼剤
IT1208537B (it) * 1985-05-10 1989-07-10 Consiglio Nazionale Ricerche Processo per la preparazione dell'isosorbide-5-monoidrato.
EP0201067B1 (de) * 1985-05-10 1991-08-07 Consiglio Nazionale Delle Ricerche Verfahren zur Herstellung von Isosorbid-5-mononitrat
FR2601386B1 (fr) * 1986-07-11 1988-11-18 Centre Nat Rech Scient Procede de bioconversion selective du dinitrate d'isosorbitol
DE3683500D1 (de) * 1986-11-05 1992-02-27 Consiglio Nazionale Ricerche Verfahren zur selektiven herstellung von isosorbid-2-nitrat, ausgehend vom isosorbid-2,5-dinitrat.
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
IT1311986B1 (it) * 1999-03-26 2002-03-22 Dinamite Dipharma S P A In For Procedimento per la preparazione di monoesteri nitrici di compostidiidrossialchilici e diidrossicicloalchilici.
GB9930778D0 (en) * 1999-12-29 2000-02-16 Archimici Ltd Compound synthesis
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz
CN104892623B (zh) * 2015-06-11 2017-08-11 山东新时代药业有限公司 一种5‑单硝酸异山梨酯的制备方法
CN113105470A (zh) * 2021-03-15 2021-07-13 海南通用康力制药有限公司 单硝酸异山梨酯的合成方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol

Also Published As

Publication number Publication date
ES509741A0 (es) 1983-02-01
ES8302716A1 (es) 1983-02-01
US4381400A (en) 1983-04-26
EP0059664B1 (de) 1984-11-21
FR2500835A1 (fr) 1982-09-03
HU191346B (en) 1987-02-27
IN157599B (de) 1986-05-03
IE820428L (en) 1982-08-27
EP0059664A1 (de) 1982-09-08
CA1182829A (en) 1985-02-19
FR2500835B1 (de) 1983-10-21
IE52602B1 (en) 1987-12-23
JPS57156492A (en) 1982-09-27
ATE10371T1 (de) 1984-12-15

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee