DE3112861A1 - Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische mittel - Google Patents

Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische mittel

Info

Publication number: DE3112861A1
Authority: DE; Germany
Prior art keywords: urea; carbonyl; methoxy; methylergoline; dicyclohexyl
Prior art date: 1980-04-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

DE19813112861

Other languages

German (de)

English (en)

Other versions

DE3112861C2 (da

Inventor

Germano Paderno Dugnano Milano Bosisio

Anna Maria Caravaggi

Enrico di Dr. Milano Salle

Patricia Dr. Salvati

Osvaldo Gallarate Varese Sapini

Aldemio Milano Temperilli

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Farmitalia Carlo Erba SpA 20159 Milano

Farmitalia Carlo Erba SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-04-03

Filing date

1981-03-31

Publication date

1982-01-07

1981-03-31 Application filed by Farmitalia Carlo Erba SpA 20159 Milano, Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SpA 20159 Milano

1982-01-07 Publication of DE3112861A1 publication Critical patent/DE3112861A1/de

1989-06-01 Application granted granted Critical

1989-06-01 Publication of DE3112861C2 publication Critical patent/DE3112861C2/de

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DE19813112861 1980-04-03 1981-03-31 Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische mittel Granted DE3112861A1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8011234		1980-04-03
GB8040575		1980-12-18

Publications (2)

Publication Number	Publication Date
DE3112861A1 true DE3112861A1 (de)	1982-01-07
DE3112861C2 DE3112861C2 (da)	1989-06-01

Family

ID=26275073

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE19813112861 Granted DE3112861A1 (de)	1980-04-03	1981-03-31	Ergolinderivate, verfahren zu deren herstellung sowie pharmazeutische mittel

Country Status (20)

Country	Link
AT (1)	AT375076B (da)
AU (1)	AU540621B2 (da)
CA (1)	CA1156648A (da)
CH (1)	CH645896A5 (da)
CS (1)	CS415291A3 (da)
DE (1)	DE3112861A1 (da)
DK (1)	DK148686C (da)
ES (1)	ES8202003A1 (da)
FI (1)	FI70412C (da)
FR (1)	FR2479829B1 (da)
GR (1)	GR74806B (da)
HK (1)	HK67287A (da)
IE (1)	IE51130B1 (da)
IL (1)	IL62519A (da)
IT (2)	IT1210473B (da)
NL (3)	NL189462C (da)
NZ (1)	NZ196670A (da)
PT (1)	PT72785B (da)
SE (1)	SE442637B (da)
YU (1)	YU43011B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2173189B (en) *	1985-02-21	1988-04-27	Maruko Pharmaceutical Co	Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB0409785D0 (en)	2004-04-30	2004-06-09	Resolution Chemicals Ltd	Preparation of cabergoline
US7339060B2 (en)	2005-03-23	2008-03-04	Resolution Chemicals, Ltd.	Preparation of cabergoline
GB0505965D0 (en)	2005-03-23	2005-04-27	Resolution Chemicals Ltd	Preparation of cabergoline
US7939665B2 (en)	2007-05-04	2011-05-10	Apotex Pharmachem Inc.	Efficient process for the preparation of cabergoline and its intermediates
EP2067780A1 (en) *	2007-12-07	2009-06-10	Axxonis Pharma AG	Ergoline derivatives as selective radical scavengers for neurons

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2124640A1 (de) *	1970-05-18	1972-11-02	Richter Gedeon Vegyeszeti Gyar Rt., Budapest	Verfahren zur Herstellung von Dihydrolysergsäure, Dihydroisolysergsäure und Dihydrolysergsäure- und Dihydroisolysergsäurederivaten sowie Dihydrolysergsäure- und Dihydroisolysergsäurederivate und ihre Verwendung

1981
- 1981-03-26 NL NLAANVRAGE8101509,A patent/NL189462C/xx not_active IP Right Cessation
- 1981-03-30 AT AT0148481A patent/AT375076B/de not_active IP Right Cessation
- 1981-03-30 CH CH214481A patent/CH645896A5/de not_active IP Right Cessation
- 1981-03-30 NZ NZ196670A patent/NZ196670A/xx unknown
- 1981-03-30 CA CA000374134A patent/CA1156648A/en not_active Expired
- 1981-03-30 IL IL62519A patent/IL62519A/xx not_active IP Right Cessation
- 1981-03-31 AU AU68937/81A patent/AU540621B2/en not_active Expired
- 1981-03-31 YU YU851/81A patent/YU43011B/xx unknown
- 1981-03-31 DE DE19813112861 patent/DE3112861A1/de active Granted
- 1981-03-31 ES ES500911A patent/ES8202003A1/es not_active Expired
- 1981-03-31 FR FR8106422A patent/FR2479829B1/fr not_active Expired
- 1981-04-01 GR GR64542A patent/GR74806B/el unknown
- 1981-04-01 IT IT8120866A patent/IT1210473B/it active
- 1981-04-01 IE IE754/81A patent/IE51130B1/en not_active IP Right Cessation
- 1981-04-01 PT PT72785A patent/PT72785B/pt unknown
- 1981-04-01 IT IT20865/81A patent/IT1205241B/it active Protection Beyond IP Right Term
- 1981-04-02 FI FI811025A patent/FI70412C/fi not_active IP Right Cessation
- 1981-04-02 SE SE8102131A patent/SE442637B/sv not_active IP Right Cessation
- 1981-04-02 DK DK150781A patent/DK148686C/da not_active IP Right Cessation
1987
- 1987-09-17 HK HK672/87A patent/HK67287A/xx not_active IP Right Cessation
1991
- 1991-12-30 CS CS914152A patent/CS415291A3/cs unknown
1993
- 1993-06-24 NL NL930092C patent/NL930092I1/nl unknown
- 1993-06-24 NL NL930091C patent/NL930091I2/nl unknown

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2124640A1 (de) *	1970-05-18	1972-11-02	Richter Gedeon Vegyeszeti Gyar Rt., Budapest	Verfahren zur Herstellung von Dihydrolysergsäure, Dihydroisolysergsäure und Dihydrolysergsäure- und Dihydroisolysergsäurederivaten sowie Dihydrolysergsäure- und Dihydroisolysergsäurederivate und ihre Verwendung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BERDE - SCHILD: Ergot Alkaloids and related Compounds, 1978, S. 322, 459, 825, 809, 811 *

Also Published As

Publication number	Publication date
SE442637B (sv)	1986-01-20
PT72785B (en)	1982-07-26
FI811025L (fi)	1981-10-04
IE51130B1 (en)	1986-10-15
SE8102131L (sv)	1981-10-04
DE3112861C2 (da)	1989-06-01
IT1205241B (it)	1989-03-15
YU43011B (en)	1989-02-28
GR74806B (da)	1984-07-12
DK148686B (da)	1985-09-02
FR2479829A1 (fr)	1981-10-09
ES500911A0 (es)	1982-01-16
DK148686C (da)	1986-03-10
NL189462B (nl)	1992-11-16
NL930091I2 (nl)	1995-01-02
NL189462C (nl)	1993-04-16
IL62519A0 (en)	1981-05-20
ES8202003A1 (es)	1982-01-16
DK150781A (da)	1981-10-04
FI70412B (fi)	1986-03-27
AT375076B (de)	1984-06-25
CA1156648A (en)	1983-11-08
IT8120865A0 (it)	1981-04-01
PT72785A (en)	1981-05-01
IL62519A (en)	1984-01-31
AU540621B2 (en)	1984-11-29
NL8101509A (nl)	1981-11-02
HK67287A (en)	1987-09-25
IT8120866A0 (it)	1981-04-01
NZ196670A (en)	1982-12-07
ATA148481A (de)	1983-11-15
FI70412C (fi)	1986-09-19
FR2479829B1 (fr)	1987-07-24
IE810754L (en)	1981-10-03
CS415291A3 (en)	1992-06-17
YU85181A (en)	1984-02-29
NL930091I1 (nl)	1993-10-01
IT1210473B (it)	1989-09-14
NL930092I1 (nl)	1993-10-01
CH645896A5 (de)	1984-10-31
AU6893781A (en)	1981-10-08

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Legal Events

Date	Code	Title	Description
1985-03-28	8110	Request for examination paragraph 44
1988-09-29	8127	New person/name/address of the applicant	Owner name: FARMITALIA CARLO ERBA S.R.L., MAILAND/MILANO, IT
1988-09-29	8128	New person/name/address of the agent	Representative=s name: EITLE, W., DIPL.-ING. HOFFMANN, K., DIPL.-ING. DR.
1989-06-01	D2	Grant after examination
1989-11-30	8364	No opposition during term of opposition
1994-12-13	V448	Application of spc	Free format text: PRODUCT NAME: CABERGOLIN; REGISTRATION NO/DATE: 26573.00.00, 19940615 Spc suppl protection certif: 194 75 024 Filing date: 19941213
1997-08-14	8327	Change in the person/name/address of the patent owner	Owner name: PHARMACIA & UPJOHN S.P.A., MAILAND/MILANO, IT
2005-04-06	V472	Application for supplementary protection certificate rejected	Free format text: PRODUCT NAME: CABERGOLIN; REGISTRATION NO/DATE: 26573.00.00, 19940615 Spc suppl protection certif: 194 75 024 Filing date: 19941213