DE2845745C2 - - Google Patents
Info
- Publication number
- DE2845745C2 DE2845745C2 DE2845745A DE2845745A DE2845745C2 DE 2845745 C2 DE2845745 C2 DE 2845745C2 DE 2845745 A DE2845745 A DE 2845745A DE 2845745 A DE2845745 A DE 2845745A DE 2845745 C2 DE2845745 C2 DE 2845745C2
- Authority
- DE
- Germany
- Prior art keywords
- prp
- pertussis
- phosphate buffer
- isolation
- sodium phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/846,466 US4196192A (en) | 1977-10-28 | 1977-10-28 | Combined Haemophilus influenzae type b and pertussis vaccine |
US05/846,488 US4220717A (en) | 1977-12-22 | 1977-12-22 | Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2845745A1 DE2845745A1 (de) | 1979-05-10 |
DE2845745C2 true DE2845745C2 (fr) | 1987-10-01 |
Family
ID=27126641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19782845745 Granted DE2845745A1 (de) | 1977-10-28 | 1978-10-20 | Kombinationsvaccine |
Country Status (25)
Country | Link |
---|---|
JP (1) | JPS5480408A (fr) |
AR (1) | AR218932A1 (fr) |
AU (1) | AU520902B2 (fr) |
BE (1) | BE871586A (fr) |
CA (1) | CA1117866A (fr) |
CH (1) | CH649781A5 (fr) |
DD (1) | DD140701A5 (fr) |
DE (1) | DE2845745A1 (fr) |
DK (1) | DK154327C (fr) |
ES (1) | ES474611A1 (fr) |
FI (1) | FI63674C (fr) |
FR (1) | FR2407000B1 (fr) |
GB (1) | GB2007244B (fr) |
GR (1) | GR73991B (fr) |
HU (1) | HU178166B (fr) |
IE (1) | IE47474B1 (fr) |
IL (1) | IL55433A (fr) |
IT (1) | IT1107570B (fr) |
NL (1) | NL7810753A (fr) |
NO (1) | NO149611C (fr) |
NZ (1) | NZ188211A (fr) |
PH (1) | PH15882A (fr) |
PL (1) | PL210545A1 (fr) |
SE (1) | SE430753B (fr) |
YU (1) | YU250878A (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE889979A (fr) * | 1981-08-14 | 1982-02-15 | Smith Kline Rit | Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation |
CA1209036A (fr) * | 1982-08-20 | 1986-08-05 | Joseph S.C. Kuo | Vaccin combine contre haemophilus influenzae, la diphterie, la coqueluche et le tetanos |
US4744982A (en) * | 1982-08-24 | 1988-05-17 | Hunter Kenneth W | Human monoclonal antibody reactive with polyribosylribitol phosphate |
EP0471177B1 (fr) * | 1990-08-13 | 1995-10-04 | American Cyanamid Company | Hemagglutinine filamenteuse de Bordetella pertussis à titre de molécules porteuses pour vaccins conjugués |
CZ28694A3 (en) * | 1991-08-16 | 1994-05-18 | Merck & Co Inc | Process for preparing capsular polysaccharide free of lipid and endotoxin |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3395219A (en) * | 1964-12-11 | 1968-07-30 | Merck & Co Inc | Process for production of pertussis antigen |
IL24946A (en) * | 1965-01-19 | 1969-05-28 | Merck & Co Inc | Process for preparing antibodies in cilus pertussis |
US3465078A (en) * | 1965-10-21 | 1969-09-02 | Sydney Z Spiesel | Method of recovering antigens from bordetella pertussis cells |
NL174267B (nl) * | 1969-05-20 | Roussel Uclaf | Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat. | |
US3636192A (en) * | 1970-01-13 | 1972-01-18 | Us Army | Meningococcal polysaccharide vaccines |
FR2253499B1 (fr) * | 1973-12-10 | 1977-11-04 | Fabre Sa Pierre | |
DE2461439C3 (de) * | 1974-12-24 | 1980-03-20 | Behringwerke Ag, 3550 Marburg | Verfahren zur Herstellung eines schützenden Antigens von Bordetella Pertussis sowie jenes enthaltendes Mittel |
US3978209A (en) * | 1975-03-24 | 1976-08-31 | Merck & Co., Inc. | Endotoxin free meningococcus polysaccharides |
-
1978
- 1978-08-22 NZ NZ188211A patent/NZ188211A/en unknown
- 1978-08-25 IL IL55433A patent/IL55433A/xx unknown
- 1978-08-29 CA CA000310218A patent/CA1117866A/fr not_active Expired
- 1978-08-30 GR GR57127A patent/GR73991B/el unknown
- 1978-08-30 AR AR273492A patent/AR218932A1/es active
- 1978-10-20 DE DE19782845745 patent/DE2845745A1/de active Granted
- 1978-10-24 IT IT51621/78A patent/IT1107570B/it active
- 1978-10-25 PH PH21738A patent/PH15882A/en unknown
- 1978-10-26 FI FI783269A patent/FI63674C/fi not_active IP Right Cessation
- 1978-10-26 AU AU41081/78A patent/AU520902B2/en not_active Expired
- 1978-10-26 FR FR7830517A patent/FR2407000B1/fr not_active Expired
- 1978-10-27 CH CH11125/78A patent/CH649781A5/de not_active IP Right Cessation
- 1978-10-27 NO NO783635A patent/NO149611C/no unknown
- 1978-10-27 SE SE7811192A patent/SE430753B/sv not_active IP Right Cessation
- 1978-10-27 NL NL7810753A patent/NL7810753A/xx not_active Application Discontinuation
- 1978-10-27 PL PL21054578A patent/PL210545A1/xx unknown
- 1978-10-27 BE BE191385A patent/BE871586A/fr not_active IP Right Cessation
- 1978-10-27 DD DD78208715A patent/DD140701A5/de unknown
- 1978-10-27 ES ES474611A patent/ES474611A1/es not_active Expired
- 1978-10-27 GB GB7842230A patent/GB2007244B/en not_active Expired
- 1978-10-27 DK DK479578A patent/DK154327C/da not_active IP Right Cessation
- 1978-10-27 HU HU78AE546A patent/HU178166B/hu not_active IP Right Cessation
- 1978-10-27 YU YU02508/78A patent/YU250878A/xx unknown
- 1978-10-27 IE IE2146/78A patent/IE47474B1/en unknown
- 1978-10-28 JP JP13310978A patent/JPS5480408A/ja active Granted
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |