DD238792A5 - Verfahren zur herstellung von benzothiophen-derivaten - Google Patents

Verfahren zur herstellung von benzothiophen-derivaten Download PDF

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Publication number
DD238792A5
DD238792A5 DD85278412A DD27841285A DD238792A5 DD 238792 A5 DD238792 A5 DD 238792A5 DD 85278412 A DD85278412 A DD 85278412A DD 27841285 A DD27841285 A DD 27841285A DD 238792 A5 DD238792 A5 DD 238792A5
Authority
DD
German Democratic Republic
Prior art keywords
thiophene
compounds
solution
formula
mixture
Prior art date
Application number
DD85278412A
Other languages
German (de)
English (en)
Inventor
Stephen J Ray
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD238792A5 publication Critical patent/DD238792A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Organic Insulating Materials (AREA)
DD85278412A 1984-07-10 1985-07-09 Verfahren zur herstellung von benzothiophen-derivaten DD238792A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848417559A GB8417559D0 (en) 1984-07-10 1984-07-10 Anti-diarrhoeal agents

Publications (1)

Publication Number Publication Date
DD238792A5 true DD238792A5 (de) 1986-09-03

Family

ID=10563672

Family Applications (1)

Application Number Title Priority Date Filing Date
DD85278412A DD238792A5 (de) 1984-07-10 1985-07-09 Verfahren zur herstellung von benzothiophen-derivaten

Country Status (20)

Country Link
US (1) US4654352A (es)
EP (1) EP0169012A1 (es)
JP (1) JPS6136281A (es)
KR (1) KR860001094A (es)
CN (1) CN85105193A (es)
AU (1) AU556058B2 (es)
CS (1) CS249545B2 (es)
DD (1) DD238792A5 (es)
DK (1) DK312485A (es)
ES (1) ES8604557A1 (es)
FI (1) FI852691L (es)
GB (1) GB8417559D0 (es)
GR (1) GR851688B (es)
HU (1) HUT38330A (es)
IL (1) IL75740A0 (es)
NO (1) NO852760L (es)
PL (1) PL254445A1 (es)
PT (1) PT80786B (es)
YU (1) YU113985A (es)
ZA (1) ZA855153B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0791589B1 (en) * 1994-04-11 2002-03-06 Chugai Seiyaku Kabushiki Kaisha 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENES WHICH INHIBIT LDL OXIDATION
CA2207083A1 (en) * 1996-07-15 1998-01-15 Brian William Grinnell Benzothiophene compounds, and uses and formulations thereof
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
US6420375B1 (en) * 1997-02-21 2002-07-16 Takeda Chemical Industries, Ltd. Fused ring compounds, process for producing the same and use thereof
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
AU756337B2 (en) * 1998-05-12 2003-01-09 Wyeth Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
EP1334094B1 (en) * 2000-11-02 2004-12-29 F. Hoffmann-La Roche Ag Cholesterol lowering benzo[b]thiophenes and benzo[d]isothiazoles
US6969730B2 (en) 2001-03-16 2005-11-29 Abbott Laboratories Amines as histamine-3 receptor ligands and their therapeutic applications
WO2006019497A2 (en) * 2004-06-17 2006-02-23 Neurocrine Biosciences, Inc. Sleep-inducing compounds and methods related thereto
JP5180807B2 (ja) 2008-12-24 2013-04-10 三菱重工業株式会社 1段静翼の冷却構造、及びガスタービン

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174411A (en) * 1966-03-02 1969-12-17 Aspro Nicholas Ltd Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
US3598839A (en) * 1969-06-30 1971-08-10 Parke Davis & Co Phenylbenzothiophene compounds
US3944672A (en) * 1972-12-13 1976-03-16 Schering Corporation Method for treating microbial infections
US4018893A (en) * 1974-05-28 1977-04-19 Schering Corporation Methods for treating microbial infections
NL7506021A (nl) * 1974-05-28 1975-12-02 Scherico Ltd Antimicrobiele verbindingen.
US4137414A (en) * 1977-09-26 1979-01-30 G. D. Searle & Co. 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds

Also Published As

Publication number Publication date
PT80786A (en) 1985-08-01
DK312485D0 (da) 1985-07-09
GB8417559D0 (en) 1984-08-15
ES8604557A1 (es) 1986-02-01
US4654352A (en) 1987-03-31
FI852691A0 (fi) 1985-07-08
HUT38330A (en) 1986-05-28
FI852691L (fi) 1986-01-11
CS249545B2 (en) 1987-03-12
CN85105193A (zh) 1987-01-28
EP0169012A1 (en) 1986-01-22
AU4471385A (en) 1986-01-16
AU556058B2 (en) 1986-10-23
ES544970A0 (es) 1986-02-01
YU113985A (en) 1987-08-31
PT80786B (en) 1987-03-26
PL254445A1 (en) 1986-07-15
GR851688B (es) 1985-11-26
IL75740A0 (en) 1985-11-29
DK312485A (da) 1986-01-11
ZA855153B (en) 1987-02-25
NO852760L (no) 1986-01-13
JPS6136281A (ja) 1986-02-20
KR860001094A (ko) 1986-02-22

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