CS249545B2 - Method of phenylbenzo(b)thiophenic derivatives production - Google Patents
Method of phenylbenzo(b)thiophenic derivatives production Download PDFInfo
- Publication number
- CS249545B2 CS249545B2 CS855105A CS510585A CS249545B2 CS 249545 B2 CS249545 B2 CS 249545B2 CS 855105 A CS855105 A CS 855105A CS 510585 A CS510585 A CS 510585A CS 249545 B2 CS249545 B2 CS 249545B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- formula
- compound
- compounds
- phenylbenzo
- thiophene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Organic Insulating Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848417559A GB8417559D0 (en) | 1984-07-10 | 1984-07-10 | Anti-diarrhoeal agents |
Publications (1)
Publication Number | Publication Date |
---|---|
CS249545B2 true CS249545B2 (en) | 1987-03-12 |
Family
ID=10563672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS855105A CS249545B2 (en) | 1984-07-10 | 1985-07-08 | Method of phenylbenzo(b)thiophenic derivatives production |
Country Status (20)
Country | Link |
---|---|
US (1) | US4654352A (es) |
EP (1) | EP0169012A1 (es) |
JP (1) | JPS6136281A (es) |
KR (1) | KR860001094A (es) |
CN (1) | CN85105193A (es) |
AU (1) | AU556058B2 (es) |
CS (1) | CS249545B2 (es) |
DD (1) | DD238792A5 (es) |
DK (1) | DK312485A (es) |
ES (1) | ES8604557A1 (es) |
FI (1) | FI852691L (es) |
GB (1) | GB8417559D0 (es) |
GR (1) | GR851688B (es) |
HU (1) | HUT38330A (es) |
IL (1) | IL75740A0 (es) |
NO (1) | NO852760L (es) |
PL (1) | PL254445A1 (es) |
PT (1) | PT80786B (es) |
YU (1) | YU113985A (es) |
ZA (1) | ZA855153B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4128690A1 (de) * | 1991-08-29 | 1993-03-04 | Boehringer Mannheim Gmbh | Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
EP0791589B1 (en) * | 1994-04-11 | 2002-03-06 | Chugai Seiyaku Kabushiki Kaisha | 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENES WHICH INHIBIT LDL OXIDATION |
CA2207083A1 (en) * | 1996-07-15 | 1998-01-15 | Brian William Grinnell | Benzothiophene compounds, and uses and formulations thereof |
CA2207141A1 (en) * | 1996-07-15 | 1998-01-15 | David Thompson Berg | Benzothiophene compounds, and uses and formulations thereof |
US5792798A (en) * | 1996-07-29 | 1998-08-11 | Eli Lilly And Company | Method for inhibiting plasminogen activator inhibitor 1 |
US6420375B1 (en) * | 1997-02-21 | 2002-07-16 | Takeda Chemical Industries, Ltd. | Fused ring compounds, process for producing the same and use thereof |
US6251936B1 (en) | 1998-05-12 | 2001-06-26 | American Home Products Corporation | Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia |
AU756337B2 (en) * | 1998-05-12 | 2003-01-09 | Wyeth | Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia |
EP1334094B1 (en) * | 2000-11-02 | 2004-12-29 | F. Hoffmann-La Roche Ag | Cholesterol lowering benzo[b]thiophenes and benzo[d]isothiazoles |
US6969730B2 (en) | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
WO2006019497A2 (en) * | 2004-06-17 | 2006-02-23 | Neurocrine Biosciences, Inc. | Sleep-inducing compounds and methods related thereto |
JP5180807B2 (ja) | 2008-12-24 | 2013-04-10 | 三菱重工業株式会社 | 1段静翼の冷却構造、及びガスタービン |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1174411A (en) * | 1966-03-02 | 1969-12-17 | Aspro Nicholas Ltd | Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture |
US3598839A (en) * | 1969-06-30 | 1971-08-10 | Parke Davis & Co | Phenylbenzothiophene compounds |
US3944672A (en) * | 1972-12-13 | 1976-03-16 | Schering Corporation | Method for treating microbial infections |
US4018893A (en) * | 1974-05-28 | 1977-04-19 | Schering Corporation | Methods for treating microbial infections |
NL7506021A (nl) * | 1974-05-28 | 1975-12-02 | Scherico Ltd | Antimicrobiele verbindingen. |
US4137414A (en) * | 1977-09-26 | 1979-01-30 | G. D. Searle & Co. | 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds |
-
1984
- 1984-07-10 GB GB848417559A patent/GB8417559D0/en active Pending
-
1985
- 1985-06-28 US US06/750,115 patent/US4654352A/en not_active Expired - Lifetime
- 1985-07-05 EP EP85304793A patent/EP0169012A1/en not_active Withdrawn
- 1985-07-08 GR GR851688A patent/GR851688B/el unknown
- 1985-07-08 CS CS855105A patent/CS249545B2/cs unknown
- 1985-07-08 CN CN198585105193A patent/CN85105193A/zh active Pending
- 1985-07-08 FI FI852691A patent/FI852691L/fi not_active Application Discontinuation
- 1985-07-08 ES ES544970A patent/ES8604557A1/es not_active Expired
- 1985-07-08 PL PL25444585A patent/PL254445A1/xx unknown
- 1985-07-08 IL IL75740A patent/IL75740A0/xx unknown
- 1985-07-08 PT PT80786A patent/PT80786B/pt unknown
- 1985-07-09 NO NO852760A patent/NO852760L/no unknown
- 1985-07-09 HU HU852658A patent/HUT38330A/hu unknown
- 1985-07-09 KR KR1019850004875A patent/KR860001094A/ko not_active Application Discontinuation
- 1985-07-09 YU YU01139/85A patent/YU113985A/xx unknown
- 1985-07-09 JP JP15117785A patent/JPS6136281A/ja active Pending
- 1985-07-09 DK DK312485A patent/DK312485A/da not_active Application Discontinuation
- 1985-07-09 DD DD85278412A patent/DD238792A5/de unknown
- 1985-07-09 AU AU44713/85A patent/AU556058B2/en not_active Ceased
- 1985-07-09 ZA ZA855153A patent/ZA855153B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
PT80786A (en) | 1985-08-01 |
DK312485D0 (da) | 1985-07-09 |
GB8417559D0 (en) | 1984-08-15 |
ES8604557A1 (es) | 1986-02-01 |
US4654352A (en) | 1987-03-31 |
FI852691A0 (fi) | 1985-07-08 |
HUT38330A (en) | 1986-05-28 |
FI852691L (fi) | 1986-01-11 |
CN85105193A (zh) | 1987-01-28 |
EP0169012A1 (en) | 1986-01-22 |
AU4471385A (en) | 1986-01-16 |
AU556058B2 (en) | 1986-10-23 |
ES544970A0 (es) | 1986-02-01 |
YU113985A (en) | 1987-08-31 |
PT80786B (en) | 1987-03-26 |
PL254445A1 (en) | 1986-07-15 |
GR851688B (es) | 1985-11-26 |
DD238792A5 (de) | 1986-09-03 |
IL75740A0 (en) | 1985-11-29 |
DK312485A (da) | 1986-01-11 |
ZA855153B (en) | 1987-02-25 |
NO852760L (no) | 1986-01-13 |
JPS6136281A (ja) | 1986-02-20 |
KR860001094A (ko) | 1986-02-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69221059T2 (de) | Indolderivate und antiulcerose Zubereitungen | |
US4207324A (en) | 1,2-Di-Substituted-4-haloimidazole-5-acetic acid derivatives and their use | |
KR100437751B1 (ko) | 벤조니트릴및벤조플루오라이드 | |
WO1996002537A1 (en) | Benzocondensed five membered heterocycle carboxamides as 5ht2b/2c receptor antagonists | |
JP2001501629A (ja) | N―置換アザ複素環式化合物 | |
CS249545B2 (en) | Method of phenylbenzo(b)thiophenic derivatives production | |
CA2059127A1 (en) | Medicaments useful in cancer therapy and having antihistaminic properties | |
JPS6289679A (ja) | ピペリジン誘導体 | |
JPS639515B2 (es) | ||
JPH0692404B2 (ja) | 5ht▲下3▼拮抗剤としてのアリールチアゾリルイミダゾール類 | |
JP2001502307A (ja) | 1,4―ジ置換ピペラジン | |
US20020035134A1 (en) | Indoline derivatives useful as 5-HT-2C receptor antagonists | |
CS207619B2 (en) | Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on | |
US4144337A (en) | 1,4-Substituted piperazinyl derivatives useful as psychostimulants | |
AU598510B2 (en) | Pyrrolo (1,2-a)(4,1) benzoxazepine derivatives | |
US4448777A (en) | 1-Phenylindazole-3-one compounds, process and intermediates for their preparation, and pharmaceutical compositions containing same | |
US4806560A (en) | Imidazo[4,5-b]pyridin-2-one derivatives | |
SU895291A3 (ru) | Способ получени производных 4-амино-2-пиперидинохиназолина или их солей с фармацевтически приемлимыми кислотами | |
JPS6360750B2 (es) | ||
JPS6130588A (ja) | ベンゾ〔c〕〔1,8〕ナフチリジン、その製造方法及びその使用、並びにこれらの化合物を含有する調製剤 | |
JP2001501628A (ja) | N―置換化アザ複素環式化合物 | |
US4564685A (en) | Diphenylmethane compounds | |
US5011838A (en) | Pharmacologically active 2-substituted 3-(2-ethoxyethyl) imidazo[4,5-b]pyridines and pharmaceutical compositions containing them | |
US4006145A (en) | 10,11-Dihydro dibenzo(b,f)thiepin derivatives | |
US4006144A (en) | 10,11-Dihydro-dibenzo(b,f)thiepin derivatives |