ZA855153B - Benzothiophene anti-diarrhoeal agents - Google Patents

Benzothiophene anti-diarrhoeal agents

Info

Publication number
ZA855153B
ZA855153B ZA855153A ZA855153A ZA855153B ZA 855153 B ZA855153 B ZA 855153B ZA 855153 A ZA855153 A ZA 855153A ZA 855153 A ZA855153 A ZA 855153A ZA 855153 B ZA855153 B ZA 855153B
Authority
ZA
South Africa
Prior art keywords
benzothiophene
diarrhoeal agents
diarrhoeal
agents
benzothiophene anti
Prior art date
Application number
ZA855153A
Other languages
English (en)
Inventor
Stephen James Ray
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA855153B publication Critical patent/ZA855153B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Organic Insulating Materials (AREA)
ZA855153A 1984-07-10 1985-07-09 Benzothiophene anti-diarrhoeal agents ZA855153B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848417559A GB8417559D0 (en) 1984-07-10 1984-07-10 Anti-diarrhoeal agents

Publications (1)

Publication Number Publication Date
ZA855153B true ZA855153B (en) 1987-02-25

Family

ID=10563672

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855153A ZA855153B (en) 1984-07-10 1985-07-09 Benzothiophene anti-diarrhoeal agents

Country Status (20)

Country Link
US (1) US4654352A (es)
EP (1) EP0169012A1 (es)
JP (1) JPS6136281A (es)
KR (1) KR860001094A (es)
CN (1) CN85105193A (es)
AU (1) AU556058B2 (es)
CS (1) CS249545B2 (es)
DD (1) DD238792A5 (es)
DK (1) DK312485A (es)
ES (1) ES8604557A1 (es)
FI (1) FI852691L (es)
GB (1) GB8417559D0 (es)
GR (1) GR851688B (es)
HU (1) HUT38330A (es)
IL (1) IL75740A0 (es)
NO (1) NO852760L (es)
PL (1) PL254445A1 (es)
PT (1) PT80786B (es)
YU (1) YU113985A (es)
ZA (1) ZA855153B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
EP0791589B1 (en) * 1994-04-11 2002-03-06 Chugai Seiyaku Kabushiki Kaisha 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENES WHICH INHIBIT LDL OXIDATION
CA2207083A1 (en) * 1996-07-15 1998-01-15 Brian William Grinnell Benzothiophene compounds, and uses and formulations thereof
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
US6420375B1 (en) * 1997-02-21 2002-07-16 Takeda Chemical Industries, Ltd. Fused ring compounds, process for producing the same and use thereof
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
AU756337B2 (en) * 1998-05-12 2003-01-09 Wyeth Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
EP1334094B1 (en) * 2000-11-02 2004-12-29 F. Hoffmann-La Roche Ag Cholesterol lowering benzo[b]thiophenes and benzo[d]isothiazoles
US6969730B2 (en) 2001-03-16 2005-11-29 Abbott Laboratories Amines as histamine-3 receptor ligands and their therapeutic applications
WO2006019497A2 (en) * 2004-06-17 2006-02-23 Neurocrine Biosciences, Inc. Sleep-inducing compounds and methods related thereto
JP5180807B2 (ja) 2008-12-24 2013-04-10 三菱重工業株式会社 １段静翼の冷却構造、及びガスタービン

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174411A (en) * 1966-03-02 1969-12-17 Aspro Nicholas Ltd Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
US3598839A (en) * 1969-06-30 1971-08-10 Parke Davis & Co Phenylbenzothiophene compounds
US3944672A (en) * 1972-12-13 1976-03-16 Schering Corporation Method for treating microbial infections
US4018893A (en) * 1974-05-28 1977-04-19 Schering Corporation Methods for treating microbial infections
NL7506021A (nl) * 1974-05-28 1975-12-02 Scherico Ltd Antimicrobiele verbindingen.
US4137414A (en) * 1977-09-26 1979-01-30 G. D. Searle & Co. 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds

Also Published As

Publication number Publication date
PT80786A (en) 1985-08-01
DK312485D0 (da) 1985-07-09
GB8417559D0 (en) 1984-08-15
ES8604557A1 (es) 1986-02-01
US4654352A (en) 1987-03-31
FI852691A0 (fi) 1985-07-08
HUT38330A (en) 1986-05-28
FI852691L (fi) 1986-01-11
CS249545B2 (en) 1987-03-12
CN85105193A (zh) 1987-01-28
EP0169012A1 (en) 1986-01-22
AU4471385A (en) 1986-01-16
AU556058B2 (en) 1986-10-23
ES544970A0 (es) 1986-02-01
YU113985A (en) 1987-08-31
PT80786B (en) 1987-03-26
PL254445A1 (en) 1986-07-15
GR851688B (es) 1985-11-26
DD238792A5 (de) 1986-09-03
IL75740A0 (en) 1985-11-29
DK312485A (da) 1986-01-11
NO852760L (no) 1986-01-13
JPS6136281A (ja) 1986-02-20
KR860001094A (ko) 1986-02-22

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