CY1124471T1 - Ένα πορωδες υλικο πυριτιας προς χρηση ως ενα φαρμακευτικο ή διαιτητικο ενεργο συστατικο - Google Patents

Ένα πορωδες υλικο πυριτιας προς χρηση ως ενα φαρμακευτικο ή διαιτητικο ενεργο συστατικο

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Publication number
CY1124471T1
CY1124471T1 CY20211100628T CY211100628T CY1124471T1 CY 1124471 T1 CY1124471 T1 CY 1124471T1 CY 20211100628 T CY20211100628 T CY 20211100628T CY 211100628 T CY211100628 T CY 211100628T CY 1124471 T1 CY1124471 T1 CY 1124471T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical
active ingredient
porous silica
silica material
range
Prior art date
Application number
CY20211100628T
Other languages
English (en)
Inventor
Robert CSIKASZ
Tore Bengtsson
Natalia KUPFERSCHMIDT
Alfonso E GARCIA-BENNETT
Original Assignee
Sigrid Therapeutics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigrid Therapeutics Ab filed Critical Sigrid Therapeutics Ab
Publication of CY1124471T1 publication Critical patent/CY1124471T1/el

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/113—Silicon oxides; Hydrates thereof
    • C01B33/12—Silica; Hydrates thereof, e.g. lepidoic silicic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/12—Surface area
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/14—Pore volume
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2006/00—Physical properties of inorganic compounds
    • C01P2006/16—Pore diameter
    • C01P2006/17—Pore diameter distribution
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Silicon Compounds (AREA)

Abstract

Ένα πορώδες υλικό πυριτίας προς χρήση ως ένα φαρμακευτικό ή διαιτητικό ενεργό συστατικό που έχει πόρους στην περιοχή μεσοκλίμακας (2-50 nm), όπου το μέσο μέγεθος πόρου των πόρων στην περιοχή μεσοκλίμακας είναι στην περιοχή από 2 έως 25 nm, και η κατανομή μεγέθους πόρων (PSD) στην περιοχή μεσοκλίμακας είναι τέτοια ώστε τουλάχιστον το 80% των πόρων να εμπίπτει στην περιοχή από 2 έως 25 nm.
CY20211100628T 2012-11-06 2021-07-13 Ένα πορωδες υλικο πυριτιας προς χρηση ως ενα φαρμακευτικο ή διαιτητικο ενεργο συστατικο CY1124471T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261723019P 2012-11-06 2012-11-06
PCT/EP2013/073200 WO2014072363A1 (en) 2012-11-06 2013-11-06 A porous silica material for use as a pharmaceutical or dietary active ingredient

Publications (1)

Publication Number Publication Date
CY1124471T1 true CY1124471T1 (el) 2022-07-22

Family

ID=49639855

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100628T CY1124471T1 (el) 2012-11-06 2021-07-13 Ένα πορωδες υλικο πυριτιας προς χρηση ως ενα φαρμακευτικο ή διαιτητικο ενεργο συστατικο

Country Status (19)

Country Link
US (2) US10695294B2 (el)
EP (2) EP2916852B1 (el)
JP (2) JP6421124B2 (el)
CN (2) CN113069467A (el)
AU (1) AU2013343565B2 (el)
BR (1) BR112015010118A2 (el)
CA (2) CA3024640A1 (el)
CY (1) CY1124471T1 (el)
DK (1) DK2916852T3 (el)
ES (1) ES2878017T3 (el)
HR (1) HRP20211036T1 (el)
HU (1) HUE055017T2 (el)
IL (1) IL238538B (el)
LT (1) LT2916852T (el)
PH (1) PH12015501010A1 (el)
PL (1) PL2916852T3 (el)
PT (1) PT2916852T (el)
SI (1) SI2916852T1 (el)
WO (1) WO2014072363A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014100522A1 (en) 2012-12-21 2014-06-26 National Health Research Institutes Mesoporous silica nanoparticles for oil absorption
CN111479555A (zh) * 2017-12-13 2020-07-31 L.I.瑞思有限公司 乳铁蛋白和二氧化硅的复合物、制备方法和口腔卫生组合物
GB201803363D0 (en) 2018-03-01 2018-04-18 Sigrid Therapeutics Ab New materials and uses thereof
WO2020212418A1 (en) * 2019-04-15 2020-10-22 Nanologica Ab Empty porous particles for use in treatment, prevention and/or postponement of degeneration of neurodegenerative diseases, neurons and glia.
CN110314151B (zh) * 2019-08-02 2020-06-02 深圳国佳产业基金管理有限公司 医用介孔二氧化硅材料及其应用
US20220332951A1 (en) * 2019-09-30 2022-10-20 Zeroignition Technologies Inc. Thermally insulating and fire retardant material and method for making same
CN114195885B (zh) * 2022-01-12 2024-04-26 杭州隆基生物技术有限公司 一种单克隆抗体组合物提纯方法
WO2023148307A1 (en) 2022-02-04 2023-08-10 Sigrid Therapeutics Ab Oral care composition comprising porous silica particles
GB202212239D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New dietary supplements
GB202212240D0 (en) 2022-08-23 2022-10-05 Sigrid Therapeutics Ab New formulations and medical uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4185088A (en) 1977-02-17 1980-01-22 Merck & Co., Inc. Non-adhesive ionene quaternary polymer compositions useful as bile acid sequestrants
US4180566A (en) * 1978-05-15 1979-12-25 W. R. Grace & Co. Silica gel method of reducing blood lipid concentration
US4824672A (en) * 1986-06-06 1989-04-25 Hauser-Kuhrts, Inc. Method and composition for reducing serum cholesterol
US5401466A (en) * 1993-06-01 1995-03-28 Miles Inc. Device for the direct measurement of low density lipoprotein cholesterol
EP0778027A3 (de) 1995-12-04 1998-04-01 Helmut Univ.-Prof. Dr. Wachter Verwendung von Kieselerde zur Herstellung von Arzneimitteln
EP0911078A1 (en) * 1997-10-20 1999-04-28 Hitachi Metals, Ltd. Photocatalyst-supporting body and photocatalytic apparatus
CN1305376A (zh) * 1998-06-30 2001-07-25 武田药品工业株式会社 治疗糖尿病的药物组合物
EP1202745A4 (en) * 1999-08-16 2004-09-22 Henceforth Hibernia Inc THERAPEUTIC AND PROPHYLACTIC COMPOSITIONS CONTAINING CATALYTIC BIOMIMETIC SOLIDS AND METHODS OF PREPARING AND USING SAME
DE60106623T2 (de) 2000-07-28 2006-02-02 F. Hoffmann-La Roche Ag Neue pharmazeutische zusammensetzung
US7074440B2 (en) * 2002-05-01 2006-07-11 Rulin Xiu Compositions and methods for body weight loss
JP2004345895A (ja) * 2003-05-21 2004-12-09 Ajinomoto Co Inc メソポーラスシリカ及びその製造方法
JP2005289853A (ja) * 2004-03-31 2005-10-20 Ajinomoto Co Inc 経口リン酸吸着剤
GB0515353D0 (en) 2005-07-27 2005-08-31 Psimedica Ltd Food
KR100857411B1 (ko) 2006-07-21 2008-09-08 한올제약주식회사 리파아제 저해제의 경구 투여용 방출조절 약학 제제 및이의 제조 방법
WO2009101110A2 (en) 2008-02-11 2009-08-20 Alfonso Garcia-Bennet Method for manufacturing mesoporous materials, materials so produced and use of mesoporous materials.
TW200936130A (en) * 2008-02-26 2009-09-01 Lundbeck & Co As H Uses of indane compounds
WO2009120810A2 (en) * 2008-03-25 2009-10-01 Cns Protein Therapeutics, Inc. Neurodegenerative disorders
JP2010065023A (ja) * 2008-08-14 2010-03-25 Lion Corp 脂溶性ビタミンおよび／または脂溶性色素含有粉体
JP2012506904A (ja) * 2008-10-28 2012-03-22 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ 難水溶性成分のためのメソ多孔性材料賦形剤
DE102009026686A1 (de) * 2009-06-03 2010-12-23 Airbus France Anordnung zum Blitzschutz einer elektronischen Einheit
WO2011113879A1 (en) 2010-03-17 2011-09-22 Nanologica Ab Enhanced folic acid fluorescent material, multifluorescent porous compositions of matter and potential applications thereof.
WO2012004291A1 (en) * 2010-07-06 2012-01-12 Nanologica Ab Improved method for stem cell differentiation in vivo by delivery of morphogenes with mesoporous silica and corresponding pharmaceutical active ingredients.
GB201212866D0 (en) 2012-07-20 2012-09-05 Formac Pharmaceuticals Nv Dry granulates of mesoporous silica powders
KR102237799B1 (ko) 2012-11-14 2021-04-08 더블유.알. 그레이스 앤드 캄파니-콘. 생물학적 활성 물질 및 비-정렬된 무기 산화물을 함유하는 조성물
WO2014100522A1 (en) 2012-12-21 2014-06-26 National Health Research Institutes Mesoporous silica nanoparticles for oil absorption

Also Published As

Publication number Publication date
AU2013343565B2 (en) 2018-07-26
PL2916852T3 (pl) 2021-11-02
US20200390703A1 (en) 2020-12-17
HRP20211036T1 (hr) 2021-10-01
EP3892285A2 (en) 2021-10-13
US20150258028A1 (en) 2015-09-17
EP3892285A3 (en) 2021-11-17
EP2916852B1 (en) 2021-04-14
JP2015536939A (ja) 2015-12-24
JP2019023222A (ja) 2019-02-14
ES2878017T3 (es) 2021-11-18
HUE055017T2 (hu) 2021-10-28
DK2916852T3 (en) 2021-05-10
CA2890171A1 (en) 2014-05-15
EP2916852A1 (en) 2015-09-16
SI2916852T1 (sl) 2021-08-31
PT2916852T (pt) 2021-06-15
IL238538B (en) 2019-06-30
CN105188720A (zh) 2015-12-23
JP6752858B2 (ja) 2020-09-09
AU2013343565A1 (en) 2015-05-21
BR112015010118A2 (pt) 2017-07-11
PH12015501010A1 (en) 2015-07-27
US10695294B2 (en) 2020-06-30
WO2014072363A1 (en) 2014-05-15
IL238538A0 (en) 2015-06-30
CA3024640A1 (en) 2014-05-15
CN113069467A (zh) 2021-07-06
JP6421124B2 (ja) 2018-11-07
LT2916852T (lt) 2021-06-25
CA2890171C (en) 2019-01-22

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