CY1110138T1 - Προσδιορισμος υψηλης διεκπεραιωτικοτητας της δραστικοτητας lp-pla2 - Google Patents

Προσδιορισμος υψηλης διεκπεραιωτικοτητας της δραστικοτητας lp-pla2

Info

Publication number
CY1110138T1
CY1110138T1 CY20101100572T CY101100572T CY1110138T1 CY 1110138 T1 CY1110138 T1 CY 1110138T1 CY 20101100572 T CY20101100572 T CY 20101100572T CY 101100572 T CY101100572 T CY 101100572T CY 1110138 T1 CY1110138 T1 CY 1110138T1
Authority
CY
Cyprus
Prior art keywords
pla2
activity
determination
samples
determining
Prior art date
Application number
CY20101100572T
Other languages
English (en)
Inventor
Yun-Fu Hu
George T Walker
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of CY1110138T1 publication Critical patent/CY1110138T1/el

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/918Carboxylic ester hydrolases (3.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Color Electrophotography (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Αυτή η εφεύρεση σχετίζεται με μέθοδο καθορισμού της δραστικότητας Lp-PLA2 σε πλήθος δειγμάτων από ζώα. Η εφεύρεση σχετίζεται επίσης με κιτ για καθαρισμό της δραστικότητας Lp-PLA2 σε πλήθος δειγμάτων.
CY20101100572T 2003-05-28 2010-06-21 Προσδιορισμος υψηλης διεκπεραιωτικοτητας της δραστικοτητας lp-pla2 CY1110138T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47377703P 2003-05-28 2003-05-28
EP04753533A EP1633864B1 (en) 2003-05-28 2004-05-27 High throughput assay of lp-pla2 activity

Publications (1)

Publication Number Publication Date
CY1110138T1 true CY1110138T1 (el) 2015-01-14

Family

ID=33551459

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20101100572T CY1110138T1 (el) 2003-05-28 2010-06-21 Προσδιορισμος υψηλης διεκπεραιωτικοτητας της δραστικοτητας lp-pla2

Country Status (13)

Country Link
US (1) US7531316B2 (el)
EP (2) EP2253702A1 (el)
JP (2) JP4892350B2 (el)
AT (1) ATE463562T1 (el)
CY (1) CY1110138T1 (el)
DE (1) DE602004026439D1 (el)
DK (1) DK1633864T3 (el)
ES (1) ES2341772T3 (el)
HR (1) HRP20100285T1 (el)
PL (1) PL1633864T3 (el)
PT (1) PT1633864E (el)
SI (1) SI1633864T1 (el)
WO (1) WO2005001416A2 (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4892350B2 (ja) 2003-05-28 2012-03-07 グラクソ グループ リミテッド Lp−PLA2活性のハイスループットアッセイ
DK1718967T3 (da) 2004-02-03 2013-06-03 Diadexus Inc Metoder til at detektere Lp-PLA2 aktivitet
EP1735457A4 (en) 2004-04-16 2007-08-29 Glaxo Group Ltd METHODS FOR DETECTING Lp-PLA2 ACTIVITY AND INHIBITION OF Lp-PLA2 ACTIVITY
US20150017671A1 (en) 2004-04-16 2015-01-15 Yaping Shou Methods for detecting lp-pla2 activity and inhibition of lp-pla2 activity
US20140283157A1 (en) 2013-03-15 2014-09-18 Diadexus, Inc. Lipoprotein-associated phospholipase a2 antibody compositions and methods of use
EP3258269B1 (en) * 2015-02-10 2019-06-05 Shenzhen New Industries Biomedical Engineering Co. Ltd. Reagent kit used for detecting lipoprotein-associated phospholipase a2, and preparation method and application for reagent kit
CN104820097A (zh) * 2015-05-22 2015-08-05 北京协和洛克生物技术有限责任公司 一种定量检测样本中脂蛋白磷脂酶a2浓度的液态芯片试剂盒及其制备方法
WO2017221795A1 (ja) 2016-06-22 2017-12-28 旭化成ファーマ株式会社 Lp-PLA2活性の測定

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3204681B2 (ja) 1991-05-24 2001-09-04 株式会社シノテスト 新規なエーテル型チオリン脂質化合物およびその製造法
EP0974663A1 (en) * 1993-06-25 2000-01-26 Smithkline Beecham Plc Lipoprotein associated phospholipase A2, inhibitors thereof and use of same in diagnosis and therapy
JPH0759597A (ja) 1993-08-23 1995-03-07 Shinotesuto:Kk 血小板活性化因子アセチルヒドロラーゼ活性測定方法
DK0673426T3 (da) * 1993-10-06 2001-08-27 Icos Corp Blodpladeaktiveringsfaktor-acetylhydrolase
US6146625A (en) * 1993-10-06 2000-11-14 Icos Corporation Platelet-activating factor acetylhydrolase
JPH1017600A (ja) 1996-06-28 1998-01-20 Suntory Ltd 血小板活性化因子アセチルヒドロラーゼおよびその遺伝子
JP4220603B2 (ja) 1998-12-02 2009-02-04 アルフレッサファーマ株式会社 血小板活性化因子アセチルヒドロラーゼ活性の測定方法
US20020102231A1 (en) * 1999-05-07 2002-08-01 Icos Corporation Therapeutic uses of PAF-AH products in diabetes
FR2815857B1 (fr) 2000-10-30 2003-02-14 Oreal Composition, notamment cosmetique, renfermant un retinoide et une silicone benzotriazole
ATE269342T1 (de) 2001-12-07 2004-07-15 Sirs Lab Gmbh Verbindungen zur bestimmung der aktivität von phospholipase a2
US20030134082A1 (en) * 2001-12-21 2003-07-17 Morin Brian G. Carpet comprising a low-shrink backing of polypropylene tape fibers
US20070077614A1 (en) 2003-04-01 2007-04-05 Wolfert Robert L Uses of lp-pla2 in combination to assess coronary risk
JP4892350B2 (ja) 2003-05-28 2012-03-07 グラクソ グループ リミテッド Lp−PLA2活性のハイスループットアッセイ
DK1718967T3 (da) 2004-02-03 2013-06-03 Diadexus Inc Metoder til at detektere Lp-PLA2 aktivitet
EP1735457A4 (en) 2004-04-16 2007-08-29 Glaxo Group Ltd METHODS FOR DETECTING Lp-PLA2 ACTIVITY AND INHIBITION OF Lp-PLA2 ACTIVITY

Also Published As

Publication number Publication date
WO2005001416A2 (en) 2005-01-06
WO2005001416A3 (en) 2005-03-17
DE602004026439D1 (de) 2010-05-20
ES2341772T3 (es) 2010-06-28
ATE463562T1 (de) 2010-04-15
EP2253702A1 (en) 2010-11-24
HRP20100285T1 (hr) 2010-06-30
DK1633864T3 (da) 2010-07-12
JP4892350B2 (ja) 2012-03-07
US7531316B2 (en) 2009-05-12
SI1633864T1 (sl) 2010-07-30
EP1633864A4 (en) 2006-06-14
JP5637959B2 (ja) 2014-12-10
JP2012050443A (ja) 2012-03-15
PL1633864T3 (pl) 2010-09-30
EP1633864A2 (en) 2006-03-15
JP2007502131A (ja) 2007-02-08
PT1633864E (pt) 2010-06-24
US20070065892A1 (en) 2007-03-22
EP1633864B1 (en) 2010-04-07

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