CO7141413A2 - Proceso para la preparación de derivados de 2-(1-hidroxi-alquil)-cromen-4-ona ópticamente puros y opcionalmente sustituidos y su uso en la preparación de compuestos farmacéuticos - Google Patents
Proceso para la preparación de derivados de 2-(1-hidroxi-alquil)-cromen-4-ona ópticamente puros y opcionalmente sustituidos y su uso en la preparación de compuestos farmacéuticosInfo
- Publication number
- CO7141413A2 CO7141413A2 CO14266920A CO14266920A CO7141413A2 CO 7141413 A2 CO7141413 A2 CO 7141413A2 CO 14266920 A CO14266920 A CO 14266920A CO 14266920 A CO14266920 A CO 14266920A CO 7141413 A2 CO7141413 A2 CO 7141413A2
- Authority
- CO
- Colombia
- Prior art keywords
- preparation
- chromen
- hydroxy
- alkyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente invención hace referencia a compuestos útilescomo intermedios farmacéuticos, a procesos para lapreparación de intermedios, a intermedios utilizados en losprocesos y al uso de los intermedios en la preparación decompuestos farmacéuticos. En particular, la presenteinvención comprende los derivados de 2-(1-hidroxi-alquil)-cromen-4-ona enantioméricamente puros y opcionalmentesustituidos representados mediante las fórmulas (IA) y (IB),los procesos para preparar los derivados de alcohol y su usoen la preparación de compuestos farmacéuticos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1737CH2012 | 2012-05-04 | ||
US201261671956P | 2012-07-16 | 2012-07-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO7141413A2 true CO7141413A2 (es) | 2014-12-12 |
Family
ID=54193684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO14266920A CO7141413A2 (es) | 2012-05-04 | 2014-12-03 | Proceso para la preparación de derivados de 2-(1-hidroxi-alquil)-cromen-4-ona ópticamente puros y opcionalmente sustituidos y su uso en la preparación de compuestos farmacéuticos |
Country Status (25)
Country | Link |
---|---|
US (1) | US9309216B2 (es) |
EP (1) | EP2844647B1 (es) |
JP (2) | JP6290186B2 (es) |
KR (1) | KR102073181B1 (es) |
CN (2) | CN104507922B (es) |
AP (1) | AP3547A (es) |
AU (1) | AU2013255469B2 (es) |
BR (1) | BR112014027470A2 (es) |
CA (1) | CA2871000C (es) |
CL (1) | CL2014002986A1 (es) |
CO (1) | CO7141413A2 (es) |
CY (1) | CY1123456T1 (es) |
EA (1) | EA032812B1 (es) |
HK (1) | HK1203964A1 (es) |
IL (1) | IL235181A (es) |
MX (1) | MX365250B (es) |
MY (1) | MY171207A (es) |
NZ (1) | NZ701198A (es) |
PH (1) | PH12014502453A1 (es) |
PL (1) | PL2844647T3 (es) |
RS (1) | RS61035B1 (es) |
SG (1) | SG11201407184PA (es) |
SI (1) | SI2844647T1 (es) |
WO (1) | WO2013164801A1 (es) |
ZA (1) | ZA201407769B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102012398B1 (ko) | 2009-11-05 | 2019-08-20 | 리젠 파마슈티컬스 소시에떼 아노님 | 신규한 벤조피란 키나제 조절제 |
US10130635B2 (en) | 2012-05-04 | 2018-11-20 | Rhizen Pharmaceuticals Sa | Process for preparation of optically pure and optionally substituted 2-(1-hydroxy-alkyl)-chromen-4-one derivatives and their use in preparing pharmaceuticals |
PL2844647T3 (pl) * | 2012-05-04 | 2021-01-25 | Rhizen Pharmaceuticals S.A. | Nowy sposób wytwarzania czystych optycznie i opcjonalnie podstawionych pochodnych 2-(1-hydroksyalkilo)-chromen-4-onu i ich zastosowanie do wytwarzania środków farmaceutycznych |
CA2913226C (en) | 2013-06-07 | 2023-01-03 | Rhizen Pharmaceuticals Sa | Dual selective pi3 delta and gamma kinase inhibitors |
KR20170016489A (ko) * | 2014-06-27 | 2017-02-13 | 리젠 파마슈티컬스 소시에떼 아노님 | Pi3 델타 및 감마 단백질 키나제의 선택적 이중 저해제로서 치환된 크로멘 유도체 |
WO2016054491A1 (en) | 2014-10-03 | 2016-04-07 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
EP3325462A4 (en) * | 2015-07-23 | 2019-06-19 | Pharmakea, Inc. | INHIBITORS OF LYSYL OXIDASE-LIKE 2 AND USES OF SAID INHIBITORS |
CA3013917A1 (en) | 2016-02-09 | 2017-08-17 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
WO2017214269A1 (en) | 2016-06-08 | 2017-12-14 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
WO2023130334A1 (zh) * | 2022-01-07 | 2023-07-13 | 同润生物医药(上海)有限公司 | 一种色烯-4-酮化合物及其中间体的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62201882A (ja) * | 1985-11-18 | 1987-09-05 | Yamanouchi Pharmaceut Co Ltd | イソフラボン誘導体 |
PE20060426A1 (es) * | 2004-06-02 | 2006-06-28 | Schering Corp | DERIVADOS DE ACIDO TARTARICO COMO INHIBIDORES DE MMPs, ADAMs, TACE Y TNF-alfa |
KR102012398B1 (ko) | 2009-11-05 | 2019-08-20 | 리젠 파마슈티컬스 소시에떼 아노님 | 신규한 벤조피란 키나제 조절제 |
MX365160B (es) * | 2011-05-04 | 2019-05-24 | Rhizen Pharmaceuticals Sa | Compuestos novedosos como moduladores de proteína cinasas. |
PL2844647T3 (pl) * | 2012-05-04 | 2021-01-25 | Rhizen Pharmaceuticals S.A. | Nowy sposób wytwarzania czystych optycznie i opcjonalnie podstawionych pochodnych 2-(1-hydroksyalkilo)-chromen-4-onu i ich zastosowanie do wytwarzania środków farmaceutycznych |
DK3260455T3 (da) * | 2012-07-04 | 2019-06-11 | Rhizen Pharmaceuticals S A | Selektive pi3k delta-hæmmere |
-
2013
- 2013-05-03 PL PL13729095T patent/PL2844647T3/pl unknown
- 2013-05-03 SG SG11201407184PA patent/SG11201407184PA/en unknown
- 2013-05-03 KR KR1020147034065A patent/KR102073181B1/ko active IP Right Grant
- 2013-05-03 AU AU2013255469A patent/AU2013255469B2/en not_active Ceased
- 2013-05-03 NZ NZ701198A patent/NZ701198A/en not_active IP Right Cessation
- 2013-05-03 BR BR112014027470A patent/BR112014027470A2/pt not_active Application Discontinuation
- 2013-05-03 CA CA2871000A patent/CA2871000C/en not_active Expired - Fee Related
- 2013-05-03 US US14/398,902 patent/US9309216B2/en not_active Expired - Fee Related
- 2013-05-03 EA EA201491818A patent/EA032812B1/ru unknown
- 2013-05-03 WO PCT/IB2013/053544 patent/WO2013164801A1/en active Application Filing
- 2013-05-03 CN CN201380023361.1A patent/CN104507922B/zh not_active Expired - Fee Related
- 2013-05-03 MX MX2014013426A patent/MX365250B/es active IP Right Grant
- 2013-05-03 RS RS20201267A patent/RS61035B1/sr unknown
- 2013-05-03 EP EP13729095.3A patent/EP2844647B1/en active Active
- 2013-05-03 CN CN201810028555.5A patent/CN108084138A/zh active Pending
- 2013-05-03 JP JP2015509560A patent/JP6290186B2/ja not_active Expired - Fee Related
- 2013-05-03 MY MYPI2014003098A patent/MY171207A/en unknown
- 2013-05-03 SI SI201331803T patent/SI2844647T1/sl unknown
- 2013-05-03 AP AP2014008087A patent/AP3547A/xx active
-
2014
- 2014-10-19 IL IL235181A patent/IL235181A/en active IP Right Grant
- 2014-10-24 ZA ZA2014/07769A patent/ZA201407769B/en unknown
- 2014-11-03 PH PH12014502453A patent/PH12014502453A1/en unknown
- 2014-11-04 CL CL2014002986A patent/CL2014002986A1/es unknown
- 2014-12-03 CO CO14266920A patent/CO7141413A2/es unknown
-
2015
- 2015-05-19 HK HK15104774.7A patent/HK1203964A1/xx unknown
-
2017
- 2017-12-14 JP JP2017239643A patent/JP2018039849A/ja active Pending
-
2020
- 2020-10-15 CY CY20201100974T patent/CY1123456T1/el unknown
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