CO6260019A2 - Metodos para el tratamiento de desordenes gastrointestinales independientes de la ingesta de alimento - Google Patents

Metodos para el tratamiento de desordenes gastrointestinales independientes de la ingesta de alimento

Info

Publication number
CO6260019A2
CO6260019A2 CO10041742A CO10041742A CO6260019A2 CO 6260019 A2 CO6260019 A2 CO 6260019A2 CO 10041742 A CO10041742 A CO 10041742A CO 10041742 A CO10041742 A CO 10041742A CO 6260019 A2 CO6260019 A2 CO 6260019A2
Authority
CO
Colombia
Prior art keywords
solid particle
pharmaceutical composition
patient
independent
active agent
Prior art date
Application number
CO10041742A
Other languages
English (en)
Inventor
Ronald Lee
Darcy Mulford
Jing-Tao Wu
Stuart Atkinson
Majid Vakilynejad
Original Assignee
Takeda Pharmaceuticls North America North America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40534459&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6260019(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceuticls North America North America Inc filed Critical Takeda Pharmaceuticls North America North America Inc
Publication of CO6260019A2 publication Critical patent/CO6260019A2/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Nutrition Science (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

1.- Un método de tratamiento de un desorden gastrointestinal en un paciente en necesidad de éste, el método comprende las etapas de: Administrar a dicho paciente una composición farmacéutica que comprende una cantidad terapéuticamente efectiva de una forma de dosificación que incluye un inhibidor de la bomba de protones, en donde dicha composición farmacéutica se puede administrar a un paciente independiente de la ingesta de alimento. 2.- Un método de tratamiento de un desorden gastrointestinal en un paciente en necesidad de este, el método comprende las etapas de: Administrar a dicho paciente una composición farmacéutica que comprende una cantidad terapéuticamente efectiva de: (a) una primera partícula sólida, donde dicha primera partícula sólida comprende un agente activo y un primer recubrimiento entérico, donde el primer recubrimiento entérico libera el agente activo de la partícula sólida a un pH de cerca de 5.0 a cerca de 5.5., y (b) una segunda partícula sólida, donde dicha segunda partícula sólida comprende un agente activo y un segundo recubrimiento entérico, donde el segundo recubrimiento entérico libera el agente activo de la partícula sólida a un pH de cerca de 6.2 a cerca de 6.8; En donde la primera partícula sólida comprende desde cerca de 15% a cerca de 50% en peso de la composición farmacéutica y la segunda partícula sólida comprende desde cerca de 50% a cerca de 85% en peso de la composición farmacéutica; y Además donde dicha composición farmacéutica se puede administrar a un paciente independiente de la ingestión de alimento.
CO10041742A 2007-10-12 2010-04-12 Metodos para el tratamiento de desordenes gastrointestinales independientes de la ingesta de alimento CO6260019A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99875407P 2007-10-12 2007-10-12
US12/249,258 US8173158B2 (en) 2007-10-12 2008-10-10 Methods of treating gastrointestinal disorders independent of the intake of food

Publications (1)

Publication Number Publication Date
CO6260019A2 true CO6260019A2 (es) 2011-03-22

Family

ID=40534459

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10041742A CO6260019A2 (es) 2007-10-12 2010-04-12 Metodos para el tratamiento de desordenes gastrointestinales independientes de la ingesta de alimento

Country Status (16)

Country Link
US (1) US8173158B2 (es)
EP (1) EP2203068A4 (es)
JP (2) JP5629581B2 (es)
KR (3) KR20100116165A (es)
CN (2) CN102014638A (es)
AU (1) AU2008310735B2 (es)
BR (1) BRPI0818286A2 (es)
CA (1) CA2702356C (es)
CO (1) CO6260019A2 (es)
HK (1) HK1202441A1 (es)
IL (1) IL204886B (es)
MX (1) MX2010003917A (es)
MY (1) MY153062A (es)
RU (3) RU2013106514A (es)
SG (1) SG185296A1 (es)
WO (1) WO2009049160A1 (es)

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IL204886A0 (en) 2010-11-30
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HK1202441A1 (en) 2015-10-02
JP2014012692A (ja) 2014-01-23
MX2010003917A (es) 2012-09-28
CA2702356C (en) 2014-02-11
BRPI0818286A2 (pt) 2020-08-11
KR20150084013A (ko) 2015-07-21
WO2009049160A1 (en) 2009-04-16
JP2011500595A (ja) 2011-01-06
MY153062A (en) 2014-12-31
CA2702356A1 (en) 2009-04-16
US20090098199A1 (en) 2009-04-16
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US8173158B2 (en) 2012-05-08
EP2203068A4 (en) 2012-08-22
RU2010119041A (ru) 2011-11-20
CN102014638A (zh) 2011-04-13
CN104069088A (zh) 2014-10-01
RU2563993C1 (ru) 2015-09-27
AU2008310735A1 (en) 2009-04-16
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AU2008310735B2 (en) 2013-09-12
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