CN115845260A - Tumor electric field treatment system, electrode plate thereof and temperature detection method - Google Patents

Tumor electric field treatment system, electrode plate thereof and temperature detection method Download PDF

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Publication number
CN115845260A
CN115845260A CN202211722158.0A CN202211722158A CN115845260A CN 115845260 A CN115845260 A CN 115845260A CN 202211722158 A CN202211722158 A CN 202211722158A CN 115845260 A CN115845260 A CN 115845260A
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electric field
temperature
unit
electrode
temperature detection
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CN202211722158.0A
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CN115845260B (en
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惠嘉杰
沈琪超
应建俊
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Jiangsu Hailai Xinchuang Medical Technology Co Ltd
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Jiangsu Hailai Xinchuang Medical Technology Co Ltd
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Priority to CN202211722158.0A priority Critical patent/CN115845260B/en
Priority claimed from CN202211722158.0A external-priority patent/CN115845260B/en
Publication of CN115845260A publication Critical patent/CN115845260A/en
Priority to PCT/CN2023/127360 priority patent/WO2024088418A1/en
Priority to PCT/CN2023/141647 priority patent/WO2024131987A1/en
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Abstract

The invention discloses a tumor electric field treatment system, an electrode plate thereof and a temperature detection method, wherein the electrode plate comprises: a substrate; the temperature detection device comprises a plurality of electrode sheet units and a plurality of temperature detection units, wherein the electrode sheet units and the temperature detection units are arranged in a one-to-one correspondence mode, and the electrode sheet units are configured into at least three row groups and at least three column groups; the signal ends of the corresponding temperature detection units in each column group are connected together to be used as temperature sampling points, and the grounding ends of the corresponding temperature detection units in each row group are connected to the grounding pins together through the switch units; and the handshaking chip is suitable for performing handshaking communication with external equipment to judge the connection state of the electrode plate, and after the handshaking chip completes handshaking communication with the external equipment, the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled by the corresponding temperature sampling points by configuring the switching states of the switching units. Therefore, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores.

Description

Tumor electric field treatment system, electrode plate thereof and temperature detection method
Technical Field
The invention relates to the technical field of medical instruments, in particular to an electric field tumor treatment system, an electrode plate thereof and a temperature detection method.
Background
The tumor electric field therapy is a tumor therapy method which utilizes an electric field generator to generate a low-intensity, medium-high frequency and alternating electric field to interfere the mitosis process of tumor cells. The electric field applied by the treatment method can affect tubulin aggregation, prevent spindle formation, inhibit mitosis process, and induce cancer cell apoptosis.
At present, the tumor electric field therapy system mainly includes an electric field generating device, a switching device electrically connected to the electric field generating device, and a plurality of pairs of electrode plates electrically connected to the electric field generating device through the switching device. The electric field generating device transmits alternating electric signals for tumor electric field treatment to each pair of electrode plates through the switching device, and then the alternating electric fields are applied to the tumor parts of the patients through the electrode plates to carry out the tumor electric field treatment. When the electric field is applied to the body of a patient, heat is collected at the corresponding position where the electrode plate is attached to the skin, so that the temperature of the electrode plate attached to the tumor part of the patient corresponding to the body surface needs to be monitored in real time, when the body surface temperature is too high, the intensity of the alternating electric field needs to be adjusted in time, and the skin of the patient is prevented from being scalded at low temperature due to too high temperature.
In the related art, the electrode sheet is provided with thermistor elements on corresponding electrode units, and a plurality of thermistor elements are connected in parallel to each other, and the temperature change of the corresponding electrode unit is monitored in real time through the resistance change of the thermistor elements. For example, in an electrode sheet having 9 electrode units, 8 thermistor elements are provided, and the resistance values of the 8 thermistor elements are transmitted through a 10-core cable. When the electrode units are increased, if each electrode unit is provided with one thermistor element to achieve one hundred percent of coverage rate of the thermistor elements, comprehensive temperature monitoring is achieved, the use safety of a patient is guaranteed, and the plurality of thermistor elements are connected in parallel, cables with the same number of wires as the number of the thermistor elements need to be configured, analog temperature signals detected by each thermistor element are transmitted to the switching device in parallel, the weight of the cables of the electrode plates is increased along with the increase of the thermistor elements, the application effect between the electrode plates and the body surfaces corresponding to tumor parts of the patient is affected, the load of the patient is increased, and discomfort is caused.
Disclosure of Invention
The present invention is directed to solving, at least to some extent, one of the technical problems in the related art. Therefore, the first objective of the present invention is to provide an electrode plate for an electric field tumor therapy system, which can effectively increase the coverage rate of a temperature sensor, avoid the excessive load of the electrode plate, and maintain the application effect of the electrode plate, while controlling the number of cable cores.
The second purpose of the invention is to provide an electric field tumor therapy system.
A third object of the invention is to propose a tumor therapy device.
A fourth object of the present invention is to provide a method for detecting the temperature of a tumor therapy device.
A fifth object of the invention is to propose a computer-readable storage medium.
A sixth object of the present invention is to provide a first adapter of an electric field tumor therapy system.
The seventh purpose of the invention is to provide a second adapter of the tumor electric field treatment system.
An eighth object of the present invention is to provide an electric field generator of an electric field tumor therapy system.
In order to achieve the above object, a first aspect of the present invention provides an electrode patch for an electric field tumor therapy system, including: a substrate; the temperature detection units are arranged in one-to-one correspondence with the electrode plate units so as to detect the temperature of each electrode plate unit, wherein the electrode plate units are configured into at least three row groups and at least three column groups; the signal ends of the corresponding temperature detection units in each column group are connected together to serve as temperature sampling points, and the grounding ends of the corresponding temperature detection units in each row group are connected to the grounding pins through the switch units; and the handshaking chip is arranged on the substrate and is suitable for performing handshaking communication with external equipment so as to judge the connection state of the electrode plate, and after the handshaking communication between the handshaking chip and the external equipment is completed, the switching state of the switching unit is configured so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled by corresponding temperature sampling points.
According to the electrode plate provided by the embodiment of the invention, the plurality of electrode plate units are configured into at least one row group and at least one column group, the signal ends of the corresponding temperature detection units in each column group are connected together to be used as temperature sampling points, the grounding ends of the corresponding temperature detection units in each row group are connected to the grounding pin through the switch unit, and the handshaking chip is used for performing handshaking communication with external equipment to judge the connection state of the electrode plate, wherein after the handshaking communication between the handshaking chip and the external equipment is completed, the switching state of the switch unit is configured to enable the temperature signals detected by the corresponding temperature detection units in each row group to be simultaneously sampled by the corresponding temperature sampling points. Therefore, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the phenomenon that the load of the electrode plate is too large is avoided, and the pasting effect of the electrode plate is kept.
Further, the sampled temperature signal detected by each temperature detection unit is used for representing the type of the electrode slice.
Further, the grounding pin of the handshake chip is connected to the grounding pin through the switch unit, and the communication pin of the handshake chip is connected to the adaptor unit of the tumor electric field treatment system through a communication line.
Further, the handshake chip is configured to store energy when the communication line transmits a high level and to release energy when the communication line transmits a low level via an external energy storage element.
Further, the energy storage element is a capacitor.
Furthermore, each temperature detection unit comprises a temperature sensor and a diode, the diode is provided with an anode and a cathode, the anode of the diode is connected with the temperature sensor, and the cathode of the diode is used as the grounding end of the temperature detection unit.
Furthermore, each temperature sampling point is connected to a direct current power supply through a corresponding divider resistor.
Further, the divider resistor and the switch unit are both arranged outside the substrate.
Furthermore, the sampled temperature signal detected by each temperature detection unit is also used for representing whether the electrode plate has temperature abnormality or not.
In order to achieve the above object, a second aspect of the present invention provides an electric field tumor therapy system, comprising: at least one pair of the electrode plates; the electric field generator is used for generating alternating electric signals and transmitting the alternating electric signals to each electrode plate through the adaptor unit, the adaptor unit is used for performing handshaking communication with a handshaking chip and configuring the switching state of the switching unit after the handshaking communication is completed, and the temperature signals detected by the corresponding temperature detection units in each row group are sampled simultaneously through corresponding temperature sampling points.
According to the tumor electric field treatment system provided by the embodiment of the invention, the adapter unit is in handshake communication with the handshake chip, the switch state of the switch unit is configured after the handshake communication is completed, so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled through the corresponding temperature sampling points, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
Further, the adaptor unit comprises a first adaptor and at least one pair of second adaptors, the second adaptors being adapted to connect respective electrode pads, the first adaptor being adapted to connect each of the second adaptors to the electric field generator.
Further, the second adapter comprises a first controller and an ADC (analog to digital converter) sampling unit, the first controller is used for configuring the switching state of the switching unit when receiving a handshaking signal sent by the electric field generator, so that the handshaking chip is powered on to work, the handshaking signal is sent to the handshaking chip, whether handshaking communication with the handshaking chip is completed or not is judged according to a feedback signal of the handshaking chip, and the switching state of the switching unit is configured after the handshaking communication is completed, so that the ADC sampling unit can sample the temperature signal detected by the corresponding temperature detection unit in each row group through corresponding temperature sampling points at the same time, and a plurality of AD sampling values are obtained.
Further, the first controller is also used for identifying the type of the corresponding electrode slice according to the plurality of AD sampling values.
Further, the first controller is further configured to determine whether the temperature of the corresponding electrode plate is abnormal according to the AD sampling values in a process in which the electric field generator transmits the alternating electric signal to the corresponding electrode plate.
Furthermore, the second adapter further comprises a filtering unit, the filtering unit is arranged between the ADC sampling unit and the corresponding temperature sampling point, and the filtering unit is used for filtering the temperature signal detected by each temperature detection unit.
Further, the second adapter further includes a first communication unit, the first adapter includes a second communication unit and a second controller, the second communication unit is connected to the first communication unit, wherein the first controller is further configured to send the feedback signal of the handshake chip to the second controller, so that the second controller determines whether the handshake communication between the first controller and the handshake chip is completed according to the feedback signal of the handshake chip.
Further, the first controller is further configured to send the AD sample values to the second controller, so that the second controller identifies the type of the corresponding electrode pad according to the AD sample values.
Further, the second controller is further configured to determine whether the temperature of the corresponding electrode plate is abnormal according to the AD sampling values in a process in which the electric field generator transmits the alternating electric signal to the corresponding electrode plate.
Further, the first adaptor further comprises a third communication unit, the third communication unit is respectively connected with the second controller and the electric field generator, wherein the first controller is further configured to send the feedback signal of the handshake chip to the electric field generator through the first adaptor, so that the electric field generator can judge whether the first controller and the handshake chip complete handshake communication according to the feedback signal of the handshake chip.
Further, the first controller is further configured to send the AD sample values to the electric field generator through the first adaptor, so that the electric field generator identifies the type of the corresponding electrode sheet according to the AD sample values.
Furthermore, the electric field generator is also used for judging whether the corresponding electrode plate has abnormal temperature according to the AD sampling values in the process of transmitting the alternating electric signals to the corresponding electrode plate.
Further, the tumor electric field treatment system further comprises: at least one first connector, each said first connector adapted to connect a respective second adapter to said first adapter; at least one second connector, each said second connector adapted to connect a respective electrode pad to a corresponding second adaptor; a third connector adapted to connect the electric field generator to the first adaptor.
Further, the first connector is configured to connect the second adapter to the first adapter by way of a socket connector, the second connector is configured to connect the second adapter to the electrode pad by way of a socket connector, and the third connector is configured to connect the first adapter to the electric field generator by way of a socket connector.
Furthermore, the number of the electrode plates is 4.
To achieve the above object, a third aspect of the present invention provides a tumor therapy device, including: at least one pair of the electrode plates or the tumor electric field treatment system.
According to the tumor treatment equipment provided by the embodiment of the invention, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores through the electrode plate or the tumor electric field treatment system, so that the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
In order to achieve the above object, a fourth aspect of the present invention provides a method for detecting a temperature of an electric tumor treatment system, the electric tumor treatment system including the electrode sheet, the electric field generator, and an adapter unit, the method comprising: performing handshake communication with the handshake chip through the adapter unit to judge the connection state of the corresponding electrode slice; and when each electrode plate is successfully connected with the adapter unit, the switch state of the switch unit is configured through the adapter unit, so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled through corresponding temperature sampling points.
According to the temperature detection method of the tumor electric field treatment system, the adaptor unit and the handshake chip are used for performing handshake communication to judge the connection state of the corresponding electrode plate, and when each electrode plate is successfully connected with the adaptor unit, the switch state of the switch unit is configured through the adaptor unit, so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled through the corresponding temperature sampling points, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the phenomenon that the load of the electrode plate is too large is avoided, and the application effect of the electrode plate is maintained.
Further, the method further comprises: and identifying the type of the corresponding electrode plate according to the sampled temperature signal detected by each temperature detection unit.
Further, identifying the type of the corresponding electrode sheet according to the sampled temperature signal detected by each temperature detection unit includes: obtaining a plurality of AD sampling values according to the sampled temperature signals detected by each temperature detection unit; and determining the number of electrode plate units of the corresponding electrode plate according to the AD sampling values, and determining the type of the corresponding electrode plate according to the number of the electrode plate units.
Further, before performing handshake communication with the handshake chip through the adaptor unit, the method further includes: and configuring the switch state of the switch unit through the adapter unit so as to electrify the handshake chip for work.
Further, during the process that the electric field generator transmits the alternating electric signal to the corresponding electrode sheet, the method further comprises: and judging whether the temperature of the corresponding electrode plate is abnormal or not according to the AD sampling values.
Further, during the process that the electric field generator transmits the alternating electric signal to the corresponding electrode sheet, the method further comprises: and adjusting parameters of the alternating electric signal according to the AD sampling values.
In order to achieve the above object, a fifth embodiment of the present invention provides a computer-readable storage medium, on which a temperature detection program of a tumor electric field treatment system is stored, and when the temperature detection program of the tumor electric field treatment system is executed by a processor, the method for identifying electrode slices of the tumor electric field treatment system is implemented.
According to the computer-readable storage medium of the embodiment of the invention, by adopting the temperature detection method of the tumor electric field treatment system, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
In order to achieve the above object, a sixth aspect of the present invention provides a first adapter of a tumor electric field treatment system, including a memory, a processor, and a temperature detection program of the tumor electric field treatment system stored in the memory and operable on the processor, wherein the processor implements the temperature detection method of the tumor electric field treatment system when executing the temperature detection program of the tumor electric field treatment system.
According to the first adapter of the tumor electric field treatment system, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores by the temperature detection method of the tumor electric field treatment system, the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
In order to achieve the above object, a seventh embodiment of the present invention provides a second adaptor of a tumor electric field treatment system, which includes a memory, a processor, and a temperature detection program of the tumor electric field treatment system stored in the memory and executable on the processor, wherein the processor implements the temperature detection method of the tumor electric field treatment system when executing the temperature detection program of the tumor electric field treatment system.
According to the second adapter of the tumor electric field treatment system, disclosed by the embodiment of the invention, by the temperature detection method of the tumor electric field treatment system, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the phenomenon that the load of an electrode plate is too large is avoided, and the application effect of the electrode plate is kept.
In order to achieve the above object, an eighth aspect of the present invention provides an electric field generator of a tumor electric field treatment system, which includes a memory, a processor, and a temperature detection program of the tumor electric field treatment system stored in the memory and operable on the processor, wherein when the processor executes the temperature detection program of the tumor electric field treatment system, the aforementioned temperature detection method of the tumor electric field treatment system is implemented.
According to the electric field generator of the tumor electric field treatment system, by the temperature detection method of the tumor electric field treatment system, the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
FIG. 1 is a schematic structural diagram of an electric field tumor therapy system according to an embodiment of the present invention;
FIG. 2 is a schematic view of the structure of one electrode pad and a second adapter of FIG. 1;
FIG. 3 is a schematic structural diagram of the first adapter of FIG. 1;
FIG. 4 is a flowchart illustrating a method for detecting a temperature of a tumor electric field treatment system according to an embodiment of the present invention;
FIG. 5 is a flowchart of the operation of an electric field tumor treatment system according to an embodiment of the present invention;
FIG. 6 is a flow chart of temperature detection of the electric field tumor therapy system according to an embodiment of the present invention;
fig. 7 is a schematic structural view of an electrode sheet and a second adaptor according to another embodiment of the present invention;
fig. 8 is a schematic structural view of an electrode sheet and a second adaptor according to yet another embodiment of the present invention.
Reference numerals:
1000. tumor electric field treatment systems; 10. an electric field generator; 21. a third cable; 22. a third connector; 23. a third socket; 24. a third plug; 25. a first connector; 26. a second socket; 27. a second plug; 28. a second cable; 29. a first socket; 30. a first plug; 31. a second connector; 32. a first cable; 40. a second adapter; 42. a first communication unit; 43 resistor groups; 44. a switch unit; 45. a first controller; 46. an ADC sampling unit; 47. a filtering module; 50. an electrode sheet; 51. an electrode sheet unit; 52. a diode; 53. a temperature sensor; 54. a handshake chip; 55. an electrical functional component; 56. a substrate; 60. a first adaptor; 61. a second communication unit; 62. a second controller; 63. and a third communication unit.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
Referring to fig. 1, an electric field tumor therapy system 1000 includes: at least one pair of electrode pads 50, an adaptor unit (not numbered) and an electric field generator 10, the at least one pair of electrode pads 50 being arranged in pairs on the body surface of the patient, the adaptor unit (not numbered) comprising a first adaptor 60 and at least one pair of second adaptors 40, the second adaptors 40 being adapted to connect the respective electrode pads 50, the first adaptor 60 being adapted to connect each of the second adaptors 40 to the electric field generator 10. That is, the tumor electric field treatment system 1000 includes an electrode sheet 50 disposed on the surface of the patient, a second adaptor 40 electrically connected to the electrode sheet 50, a first adaptor 60 electrically connected to the second adaptor 40, and an electric field generator 10 electrically connected to the first adaptor 60.
The electric field generator 10 generates an alternating electric signal for tumor electric field treatment, and transmits the alternating electric signal to each pair of electrode plates 50 through the first adaptor 60 and the second adaptor 40, so that an alternating electric field is formed between the pair of electrode plates 30 to act on the tumor part of the patient for tumor treatment. In this embodiment, the tumor electric field treatment system 1000 includes two pairs of electrode pads 50, as shown in fig. 1, including an electrode pad 50X1, an electrode pad 50Y1, an electrode pad 50X2, and an electrode pad 50Y2. The electric field generator 10 generates two sets of switched alternating electric signals X1 and X2, and Y1 and Y2, wherein the alternating electric signals X1 and X2 are a set and are simultaneously applied to the pair of electrode plates 50 through the first adaptor 60 and the second adaptor 40; the alternating electrical signals Y1, Y2 are a set and are simultaneously applied to the other pair of electrode sheets 50 through the first adaptor 60 and the second adaptor 40. Wherein, the electrode plate 50X1 and the electrode plate 50X2 are a pair, and the alternating signals X1 and X2 applied to the electrode plate 50X1 and the electrode plate 50X2 are closed and opened at the same time; the electrode sheet 50Y1 and the electrode sheet 50Y2 are paired, and the alternating electric signals Y1 and Y2 applied to the electrode sheet 50Y1 and the electrode sheet 50Y2 are turned on while being turned off.
Referring to fig. 1 and 2, each electrode sheet 50 includes a backing (not shown), an electrical functional component 55 supported by the backing (not shown), and the first cable 32 electrically connected to the electrical functional component 55. A second connector 31 is connected between each electrode plate 50 and the second adaptor 40, and the second connector 31 is adapted to connect the corresponding electrode plate 50 to the corresponding second adaptor 40. The second connector 31 includes a first plug 30 disposed at an end of the first cable 32 away from the electrical function module 55 and a first socket 29 disposed on the second adapter 40, wherein the first plug 30 and the first socket 29 are connectors, that is, the second connector 31 connects the second adapter 40 with the electrode plate 50 by means of connectors.
The electrical functional component 55 includes a base plate 56, a plurality of electrode pad units 51 provided on the base plate 56, a plurality of temperature detection units, and a handshake chip 54. Each electrode sheet unit 51 may apply an alternating electric field. Each temperature detection unit is provided in one-to-one correspondence with the electrode pad units 51 to detect the temperature at the corresponding electrode pad unit 51. In fig. 2, the electrical function module 55 includes 20 electrode sheet units 51 which are provided on a substrate 56 at intervals and apply an alternating electric field to a patient, and 20 temperature detection units which are assembled on the substrate 56. Each temperature detection unit includes a temperature sensor 53 and a unidirectional conductive electronic component such as a diode 52, the diode 52 has an anode and a cathode, the anode of the diode 52 is connected to the temperature sensor 53, the cathode of the diode 52 serves as a ground terminal of the temperature detection unit, the temperature at the corresponding electrode pad unit 51 is detected by the temperature sensor 53, and the influence of the resistance values of the other temperature sensors 53 on the detected resistance value of the temperature sensor 53 is avoided by the diode 52. Each electrode sheet unit 51 has a through hole (not shown) formed in the middle thereof, and one temperature sensor 53 and one diode 52 connected in series are housed in the through hole. Optionally, the electrode sheet unit 51 is a dielectric element, such as a high dielectric ceramic sheet; the temperature sensor 53 is a thermistor; diode 52 is a low leakage current, low on-voltage diode and handshake chip 54 is an EEPROM with encryption.
The electrode sheet 50 has various types, for example: the electrode sheet 50 with 20 electrode sheet units 51 is designated as a C-type electrode sheet 50, the electrode sheet 50 with 13 electrode sheet units 51 is designated as a B-type electrode sheet 50, and the electrode sheet 50 with 9 electrode sheet units 51 is designated as an a-type electrode sheet 50. The electrode sheet 50 may also carry other numbers of electrode sheet units 51. Fig. 1 shows C-shaped electrode sheets 50, and each electrode sheet 50 is provided with 20 electrode sheet units 51. The 20 electrode sheet units 51 are arranged in a substantially array, for example, the 20 electrode sheet units 51 may be arranged in four rows and five columns, and each row has 5 electrode sheet units 51; for another example, the 20 electrode sheet units 51 may be arranged in six rows (as shown in fig. 1), where the first row and the fourth row are four electrode sheet units 51, the four electrode sheet units 51 in each of the first row and the fourth row are located in each of the second row to the fifth row, the two middle rows are six electrode sheet units 51, and the six electrode sheet units 51 in each of the two middle rows are located in each of the first row to the sixth row.
The plurality of electrode pad units 51 are configured as at least three row groups and at least three column groups, signal terminals of the corresponding temperature detection units in each column group are connected together as temperature sampling points, and ground terminals of the corresponding temperature detection units in each row group are connected to the ground pin GND in common through the switch unit 44 in the second adaptor 40. In fig. 2, 20 electrode sheet units 51 are connected in parallel to the same conductive trace of the substrate 56, corresponding to the transmission of the alternating electrical signal AC. Each temperature detection unit is provided with a signal terminal and a grounding terminal. The 20 temperature detection units are divided into four row groups and five column groups, the grounding ends of the 5 temperature detection units of each row group are all in short circuit through the same conductive trace of the substrate 56 and are connected to a grounding pin GND through the switch unit 44, and the signal ends of the 5 temperature detection units of each row group are respectively connected in parallel through the 5 conductive traces of the substrate 56; the signal ends of the 4 temperature detection units in each column group are all in short circuit through the same conductive trace of the substrate 56, the short circuit point serves as a temperature sampling point, and the grounding ends of the 4 temperature detection units in each column group are connected in parallel through the 4 conductive traces of the substrate 56.
In the example of fig. 2, the substrate 56 and the second connector 31 each include 4 ground lines (No. 1 wire, no. 2 wire, no. 3 wire, no. 4 wire) connected to the ground pin GND, 5 signal lines (No. 6 wire, no. 7 wire, no. 8 wire, no. 9 wire, no. 10 wire) transmitting an analog temperature signal detected by the corresponding temperature detection unit, and one alternating power supply line (No. 11 wire) transmitting an alternating electric signal AC. The substrate 56 and the second connector 31 each further include a communication line (wire No. 5) for communicating signals with the second adapter 40 via the handshake chip 54 provided on the substrate 56. Referring to fig. 1 and 2, the first cable 32 is electrically connected to the substrate 56, and has 11 wires, which are respectively in one-to-one correspondence with 4 ground wires (No. 1 wire, no. 2 wire, no. 3 wire, no. 4 wire) connected to the ground pin GND, 5 signal wires (No. 6 wire, no. 7 wire, no. 8 wire, no. 9 wire, no. 10 wire) transmitting the analog temperature signal detected by the corresponding temperature detection unit, one alternating power line (No. 11 wire) transmitting the alternating electrical signal AC, and one communication line (No. 5 wire) transmitting the communication signal from the one handshaking chip 54 to the second adaptor 40.
The ground pin of the handshake chip 54 is connected to a ground line (one of the No. 1, no. 2, no. 3, and No. 4 wires) and to the ground pin GND through the switch unit 44, and the communication pin of the handshake chip 54 is connected to the second adaptor 40 of the adaptor unit through a communication line (No. 5 wire). As shown in fig. 2, the handshake chip 54 is connected to the No. 5 wire of the second connector 31 to obtain power and start data communication functions, and the handshake chip 54 is connected to one ground line of the second connector 31 to obtain controllable GND electrical connection, in this embodiment, referring to fig. 2, the handshake chip 54 is connected to the No. 4 ground line of the second connector 31. The handshaking chip 54 may store energy when the communication line (line 5) is transmitting a high level and release energy when the communication line (line 5) is transmitting a low level via an external energy storage element (not shown) so that the handshaking chip 54 has sufficient charge and is operating properly. Optionally, the energy storage element is a capacitor. Thus, handshake chip 54 only needs to use 1 additional wire to operate normally. The handshake chip 54 is adapted to perform handshake communication with an external device, such as the electric field generator 10, to determine the connection state of each pair of electrode pads 50, wherein after the handshake chip 54 completes handshake communication with the electric field generator 10, the switching states of the switching units 44 are configured such that the analog temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled by the corresponding temperature sampling points. The analog temperature signals detected by each sampled temperature detection unit can be used for representing the type of the electrode plate 50 under the condition that the electrode plate 50 is qualified after conversion, and can also be used for representing whether the temperature of the electrode plate 50 is abnormal or not.
Referring to fig. 1 and 2, the second adaptor 40 includes a first controller 45, an ADC sampling unit 46, a filtering unit 47, a first communication unit 42, a switching unit 44, a resistor group 43, and the second cable 28. The first controller 45, the ADC sampling unit 46, the filtering unit 47, the first communication unit 42, the switching unit 44, and the resistor group 43 are all disposed inside the second adaptor 40. The second cable 28 and the first receptacle 29 are disposed on opposite sides of the second adapter 40.
First controller 45 is electrically connected to communication line (conductor No. 5) of second connector 31 and substrate 56 for data communication with handshake chip 54. When receiving the handshake signals sent by the electric field generator 10, the first controller 45 configures the switching state of the switching unit 44, so that the handshake chip 54 is powered on to operate, and sends the handshake signals to the handshake chip 54, and determines whether handshake communication is completed with the handshake chip 54 according to the feedback signals of the handshake chip 54, and configures the switching state of the switching unit 44 after the handshake communication is completed, so that the ADC sampling unit 46 simultaneously samples the temperature signals detected by the corresponding temperature detection units in each row group through the corresponding temperature sampling points, to obtain a plurality of AD sampling values, and further can identify the type of the corresponding electrode plate 50 according to the plurality of AD sampling values when the electrode plate 50 is qualified, and can also determine whether temperature abnormality occurs in the corresponding electrode plate 50 according to the plurality of AD sampling values in the process of transmitting alternating electric signals to the corresponding electrode plate 50 by the electric field generator 10. When the switching state of the switching unit 44 is configured, the first controller 45 may control the switching unit 44 to sequentially and individually electrically connect the 4 grounding lines 1, 2, 3, 4 in the second connector 31 to the grounding pin GND, so as to energize a set of temperature detection units connected to the corresponding one grounding line for temperature detection. When the first controller 45 controls the switching unit 44 to electrically connect one of the 4 ground lines in the second connector 31 to the ground pin GND, the first controller 45 also controls the switching unit 44 to electrically disconnect the other three ground lines in the second connector 31 from the ground pin GND.
The resistor group 43 is 5 high-precision voltage dividing resistors, and is respectively connected in series to the dc power supply VCC and 5 signal lines (No. 6, no. 7, no. 8, no. 9, and No. 10) of the second connector 31 that transmit analog temperature signals (voltage values of the temperature detection units) detected by the corresponding temperature detection units, that is, each temperature sampling point is connected to the dc power supply VCC through the corresponding voltage dividing resistor. The 5 voltage dividing resistors are respectively connected in series with the corresponding temperature detection units for voltage division, so that the voltage value of the temperature detection units can be calculated, and the voltage value can be converted into a digital temperature signal through the ADC sampling unit 46 to obtain an AD sampling value, wherein the AD sampling value corresponds to the digital temperature. Therefore, the AD sample values may be partitioned by temperature ranges so as to identify the types of the corresponding electrode pads 50 and determine whether temperature abnormality occurs in the corresponding electrode pads 50. If the AD sampling value is significantly deviated from the detected temperature range, for example, lower than 0 ℃ or higher than 50 ℃, it is determined that the temperature detection unit and the electrode plate unit 51 are not provided at the sampling point corresponding to the AD sampling value, so as to determine the number of the electrode plate units 51 to identify the type of the electrode plate 50.
The filtering unit 47 is disposed between the ADC sampling unit 46 and the corresponding temperature sampling point, and the filtering unit 47 is configured to perform filtering processing on the temperature signal detected by each temperature detection unit. The filtering unit 47 includes 5 sets of filters in one-to-one correspondence with the resistor sets 43, and functions to attenuate the intensity of the signal above the set cutoff frequency. The first group of filters is connected in series with ports 1 and 6 in the filtering unit 47; the second group of filters is connected in series with the 2 and 7 ports in the filtering unit 47; the third group of filters is connected in series with the 3 and 8 ports in the filtering unit 47; the fourth group of filters is connected in series with the 4 and 9 ports in the filtering unit 47; the fifth set of filters is connected in series with the 5, 10 ports in the filtering unit 47. Alternatively, the filter uses a first order RC low pass filter with a cut-off frequency of the alternating electrical signal AC frequency of less than 1/10. Optionally, a voltage follower may be added to the filtering unit 47 to optimize the sampling of the ADC sampling unit 46.
The ADC sampling unit 46 has 5 acquisition channels 1, 2, 3, 4, 5. The 5 acquisition channels of the ADC sampling unit 46 are electrically connected to a corresponding set of filters of the filtering unit 47. Specifically, 5 acquisition channels of the ADC sampling unit 46 are respectively connected to the ports 6, 7, 8, 9, and 10 of the filtering unit 47 in a one-to-one correspondence manner to be electrically connected to a corresponding set of filters. The ADC sampling unit 46 may convert the plurality of analog temperature signals filtered by the filtering unit 47 into a plurality of digital temperature signals to obtain a plurality of AD sampling values. The plurality of AD samples converted by the ADC sampling unit 46 are controlled by the first controller 45 to be serially transmitted to the first adaptor 60 by the first communication unit 42.
The second adaptor 40 performs data interaction with the first adaptor 60 through the first communication unit 42. The first communication unit 42 enables the first controller 45 to perform data interaction with the first adaptor 60. Alternatively, the first communication unit 42 uses a UART unit.
Referring to fig. 2, the second cable 28 of the second adaptor 40 includes 5 wires. The 5 conductors of the second cable 28 transmit alternating electrical signals AC, GND, VCC, and bidirectional serial transmission data, respectively. The GND and VCC terminals in the second adaptor 40 are connected.
Referring to fig. 1 and 3, the first adaptor 60 includes a second communication unit 61, a second controller 62, a third communication unit 63, and a third cable 21. The second communication unit 61, the second controller 62, and the third communication unit 63 are all located inside the first adaptor 60.
The first adaptor 60 and the 4 second adaptors 40 are electrically connected by a corresponding one of the first connectors 25, respectively, each of the first connectors 25 being adapted to connect the corresponding second adaptor 40 to the first adaptor 60. The first connector 25 transmits signals transmitted by the second cable 28, i.e., alternating electrical signals AC, GND, VCC, bidirectional serial transmission data. The first connector 25 includes a second plug 27 provided at an end of the second cable 28 of the second adapter 40 remote from the first receptacle 29 and a plurality of second receptacles 26 provided on the first adapter 60, the second plug 27 and the second receptacles 26 being plug connectors, i.e. the first connector 25 is configured to connect the second adapter 40 with the first adapter 60 in a plug connector manner. The third cable 21 and the plurality of second receptacles 26 are located on opposite sides of the first adaptor 60, respectively. The first adaptor 60 is provided with 4 second sockets 26, and the 4 second sockets 26 are respectively connected with the 4 second adaptors 40 connected with the four electrode plates 50 in a one-to-one corresponding manner. Each second socket 26 is provided with 5 connection terminals for transmitting signals transmitted by the second cable 28: alternating electric signals AC, GND, VCC, bidirectional serial transmission data.
Each of the 4 second sockets 26 has a connection terminal for the alternating electrical signal AC to which one of the 4 alternating electrical signals (X1, X2, Y1, Y2) is connected. The 4 second sockets 26 transmit one of the 4 alternating electrical signals (X1, X2, Y1, Y2), and are electrically connected to the electrode pads 50X1, 50X2, 50Y1, 50Y2 through a corresponding one of the second adapters 40. Wherein the second socket 26, which transmits the alternating electrical signal X1, is electrically connected with the second plug 27 of the corresponding one of the second adapters 40 connected to the electrode tab 50X 1; the second socket 26 that transmits the alternating electrical signal X2 is electrically connected to the second plug 27 of the corresponding one of the second adapters 40 connected to the electrode tab 50X 2; the second socket 26, which transmits the alternating electrical signal Y1, is electrically connected to the second plug 27 of a corresponding one of the second adapters 40 connected to the electrode pad 50Y 1; the second socket 26, which transmits the alternating electrical signal Y2, is electrically connected to the second plug 27 of a corresponding one of the second adapters 40 connected to the electrode pad 50Y2.
The first adaptor 60 is electrically connected to the electric field generator 10 via a third connector 22, and the third connector 22 is adapted to connect the electric field generator 10 to the first adaptor 60 such that the GND, VCC and the alternating electric signals X1, X2, Y1 and Y2 generated thereby of the electric field generator 10 are transmitted to the first adaptor 60 via the third connector 22. The third connector 22 comprises a third socket 23 provided at the electric field generator 10 and a third plug 24 provided at an end of the third cable 21 of the first adaptor 21 remote from the second socket 26, the third socket 23 and the third plug 24 being connectors, i.e. the third connector 22 is configured to connect the first adaptor 21 with the electric field generator 10 in the manner of a connector.
The second communication unit 61 is connected between the four first connectors 25 and the second controller 62. The second controller 62 performs data interaction with the first communication units 42 of the 4 second adapters 40 through the second communication unit 61. Alternatively, the second communication unit 61 uses a UART unit. The first controller 45 may send the feedback signal of the corresponding handshake chip 54 to the second controller 62, so that the second controller 62 determines whether the corresponding first controller 45 and the handshake chip 54 complete handshake communication according to the feedback signal of the handshake chip 54. The first controller 45 may further send the plurality of AD samples to the second controller 62, so that the second controller 62 identifies the type of the corresponding electrode sheet 50 according to the plurality of AD samples when the electrode sheet 50 is qualified, and/or determines whether the temperature of the corresponding electrode sheet 50 is abnormal according to the plurality of AD samples in the process that the electric field generator 10 transmits the alternating electric signal to the corresponding electrode sheet 50.
The second controller 62 is connected substantially between the second communication unit 61 and the third communication unit 63. The third communication unit 63 is electrically connected to the electric field generator 10 substantially through the third connector 22. The second controller 62 performs data interaction with the electric field generator 10 through the third communication unit 63. Optionally, the third communication unit 63 is an RS485-UART transceiver. The alternating electrical signals inside the first adaptor 60 correspond one-to-one to one connection terminals of the second socket 26 of the first connector 25, which transmit the alternating electrical signals (X1 or X2 or Y1 or Y2). First controller 45 may send the feedback signal of handshake chip 54 to electric field generator 10 through first adaptor 60, so that electric field generator 10 determines whether first controller 45 and handshake chip 54 complete handshake communication according to the feedback signal of handshake chip 54. The first controller 45 may further send the plurality of AD samples to the electric field generator 10 through the first adaptor 60, so that the electric field generator 10 identifies the type of the corresponding electrode sheet 50 according to the plurality of AD samples when the electrode sheet 50 is qualified, and/or determines whether the temperature of the corresponding electrode sheet 50 is abnormal according to the plurality of AD samples in the process of transmitting the alternating electrical signal to the corresponding electrode sheet 50.
As can be seen from the foregoing description, the determination of the handshake communication, the identification of the type of the electrode pads, and the identification of whether the electrode pads have a temperature abnormality may be implemented by the first controller 45 in the second adaptor 40, the second controller 62 in the first adaptor 60, or the electric field generator 10, which is not limited herein. It should be noted that the number of the electrode pads 50, the number of the electrode pad units 51 per electrode pad 50, the number of the temperature detection units, and the like are exemplary illustrations and are not intended to limit the present application.
In the above embodiment, the plurality of electrode sheet units 51 are configured into at least three row groups and at least three column groups, and the signal terminals of the corresponding temperature detection units in each column group are connected together as temperature sampling points, the ground terminals of the corresponding temperature detection units in each row group are connected to the ground pin GND through the switch unit, and the handshake chip 54 performs handshake communication with the electric field generator 10 to determine the connection state of the electrode sheet 50, wherein after the handshake communication between the handshake chip 54 and the electric field generator 10 is completed, the switch state of the switch unit 44 is configured to make the analog temperature signals detected by the corresponding temperature detection units in each row group be sampled at the same time by the corresponding temperature sampling points, so that the coverage rate of the temperature sensor can be effectively increased under the condition of controlling the number of cable cores, the load of the electrode sheet 50 is prevented from being too large, and the application effect of the electrode sheet 50 is maintained; meanwhile, based on the AD sampling value obtained by the sampling analog-to-digital conversion, the type identification of the electrode sheet 50 and the identification of whether the temperature abnormality occurs in the electrode sheet 50 can be realized.
The invention also provides a temperature detection method of the tumor electric field treatment system 1000, which is shown in fig. 4 and comprises the following steps:
in step S1, handshake communication is performed with the handshake chip 54 through the adaptor unit to determine the connection state of the corresponding electrode pad 50.
In step S2, when each electrode pad 50 is successfully connected to the adapter unit, the switching state of the switching unit 44 is configured by the adapter unit, so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled by the corresponding temperature sampling points.
Optionally, the method further comprises: and identifying the type of the corresponding electrode plate 50 according to the sampled temperature signal detected by each temperature detection unit. For example, according to the sampled analog temperature signal detected by each temperature detection unit, a plurality of AD sampling values are obtained through analog-to-digital conversion; and determining the number of 50 electrode sheet units 51 of the corresponding electrode sheet according to the AD sampling values, and determining the type of the corresponding electrode sheet 50 according to the number of the electrode sheet units 51.
Optionally, in the process of transmitting the alternating electrical signal to the corresponding electrode sheet 50 by the electric field generator 10, the method further includes: and judging whether the temperature of the corresponding electrode plate 50 is abnormal or not according to the AD sampling values.
Optionally, in the process of transmitting the alternating electrical signal to the corresponding electrode sheet 50 by the electric field generator 10, the method further includes: and adjusting the parameters of the alternating electric signal according to the AD sampling values.
For example, the flow 100 of handshaking, temperature detection, and electric field control of the tumor electric field treatment system 1000 is as shown in fig. 5. The process 100 can be applied to the electric field tumor therapy system 1000 shown in fig. 1 for electric field tumor therapy. The process 100 is not limited to be applied to the example shown in fig. 1, and the process 100 is also applied to the examples shown in fig. 7 and 8. The following steps are presented for the example shown in fig. 1.
In step 101, the tumor electric field treatment system 1000 is connected. Specifically, 4C-shaped electrode plates 50 are connected to a corresponding one of the second adapters 40, 4 second adapters 40 are connected to one of the first adapters 60, the first adapters 60 are connected to the electric field generator 10, and the electric field generator 10 is connected to the adapted power supply.
In step 102, it is detected whether a user issues a command to turn on the electric field. If the command for turning on the electric field is not detected, repeating step 102; if the electric field opening command is detected, step 103 is entered.
In step 103, after the electric field generator 10 of the tumor electric field treatment system 1000 sends a handshake signal to the X1 port (the first connector 25-X1, the second connector 40) through the first adapter 60, the first controller 45 of the second adapter 40 connected to the first connector 25-X1 receives data transmitted by the No. 5 wire on the corresponding second connector 31 to determine whether the handshake has passed, and if not, the process goes to step 105; if so, go to step 106. This decision step may occur in the second adaptor 40, in the first adaptor 60 or in the electric field generator 10. In an embodiment the determining step occurs in the second adaptor 40. Specifically, when the electrode plate 50X1 is connected normally, the handshake chip 54 can receive a handshake request signal of the electric field generator 10 and feed back a handshake state to the first controller 45 of the second adapter 40, and the first controller 45 of the second adapter 40 determines that the handshake is successful. On the contrary, when the electrode plate 50X1 is abnormally connected, the first controller 45 of the second adaptor 40 cannot obtain the feedback signal of the handshake chip 54, and the first controller 45 of the second adaptor 40 determines that the handshake fails.
In step 105, the tumor e-field therapy system 1000 issues an alarm due to a handshake failure, and then proceeds to step 102.
In step 106, after the electric field generator 10 of the electric field tumor therapy system 1000 sends a handshake signal to the X2 port (the first connector 25-X2, the second connector 40) through the first adapter 60, the first controller 45 of the second adapter 40 connected to the first connector 25-X2 receives data transmitted by the No. 5 wire on the corresponding second connector 31 to determine whether the handshake signal passes, and if the handshake signal does not pass, the process goes to step 102; if so, step 107 is entered. This decision step may occur in the second adaptor 40, in the first adaptor 60 or in the electric field generator 10. The decision step in the embodiment takes place in the second adapter 40. Specifically, when the electrode plate 50X2 is connected normally, the handshake chip 54 can receive a handshake request signal of the electric field generator 10 and feed back a handshake state to the first controller 45 of the second adapter 40, and the first controller 45 of the second adapter 40 determines that the handshake is successful. On the contrary, when the electrode plate 50X2 is abnormally connected, the first controller 45 of the second adaptor 40 cannot obtain the feedback signal of the handshake chip 54, and the first controller 45 of the second adaptor 40 determines that the handshake fails.
In step 107, after the electric field generator 10 of the electric field tumor therapy system 1000 sends a handshake signal to the Y1 port (the first connector 25-Y1 and the second connector 40) through the first adapter 60, the first controller 45 of the second adapter 40 connected to the first connector 25-Y1 receives data transmitted by the No. 5 wire on the corresponding second connector 31 to determine whether the handshake has passed, and if not, the process goes to step 102; if so, go to step 108. This decision step may occur in the second adaptor 40, in the first adaptor 60 or in the electric field generator 10. In an embodiment the determining step occurs in the second adaptor 40. Specifically, when the electrode plate 50Y1 is connected normally, the handshake chip 54 can receive a handshake request signal of the electric field generator 10 and feed back a handshake state to the first controller 45 of the second adapter 40, and the first controller 45 of the second adapter 40 determines that the handshake is successful. On the contrary, when the electrode plate 50Y1 is abnormally connected, the first controller 45 of the second adaptor 40 cannot obtain the feedback signal of the handshake chip 54, and the first controller 45 of the second adaptor 40 determines that the handshake fails.
In step 108, after the electric field generator 10 of the electric field tumor therapy system 1000 sends a handshake signal to the Y2 port (the first connector 25-Y2, the second connector 40) through the first adapter 60, the first controller 45 of the second adapter 40 connected to the first connector 25-Y2 receives data transmitted by the No. 5 wire on the corresponding second connector 31 to determine whether the handshake signal passes, and if the handshake signal does not pass, the process goes to step 102; if so, go to step 109. This decision step may occur in the second adaptor 40, in the first adaptor 60 or in the electric field generator 10. In an embodiment the determining step occurs in the second adaptor 40. Specifically, when the electrode plate 50Y2 is connected normally, the handshake chip 54 can receive a handshake request signal of the electric field generator 10 and feed back a handshake state to the first controller 45 of the second adapter 40, and the first controller 45 of the second adapter 40 determines that the handshake is successful. On the contrary, when the electrode plate 50Y2 is abnormally connected, the first controller 45 of the second adaptor 40 cannot obtain the feedback signal of the handshake chip 54, and the first controller 45 of the second adaptor 40 determines that the handshake fails.
After receiving the handshake signals of the tumor electric field therapy system 1000 in steps 103, 106, 107, and 108, the second adaptor 40 needs to control the switch module 44 through the first controller 45, so that the No. 4 wire of the second connector 31 is electrically connected to the ground pin GND, so that the handshake chip 54 can work normally. If the connections between the electric field generator 10 and the first adapter 60, between the first adapter 60 and the second adapter 40, and between the second adapter 40 and the electrode plate 50 are normal, the handshaking signals from the electric field generator 10 can finally reach the handshaking chip 54 of the electrode plate 50, and the handshaking state of the handshaking chip 54 can be fed back to the electric field generator 10. If at least one of the connection between the electric field generator 10 and the first adaptor 60, between the first adaptor 60 and the second adaptor 40, and between the second adaptor 40 and the electrode plate 50 is abnormal, the handshaking chip 54 cannot be connected with VCC and GND to form a loop, so that the second adaptor 40, the first adaptor 60, and the electric field generator 10 receive a handshaking state of null signal, and the handshaking fails.
In step 109, the electric field generator 10 of the electric field tumor therapy system 1000 sets the electric field parameters and then proceeds to step 110. The electric field parameters include the frequency, amplitude, etc. of the alternating electrical signal.
In step 110, after the first adaptor 60 sends a temperature reading request to the 2 second adaptors 40 corresponding to the first connector 25-Y1 and the first connector 25-Y2, the temperature signals are read to acquire the temperatures corresponding to the 40 temperature sensors 53 on the electrode pads 50Y1 and 50Y2. Step 111 is entered.
In step 111, the tumor electric field treatment system 1000 determines the type of the electrode sheets 50Y1 and 50Y2 according to the temperature signal, and then proceeds to step 112. The types of the electrode sheets 50Y1, 50Y2 are determined, and the number of the electrode sheet units 51 and the temperature sensors 53 of the electrode sheets 50Y1, 50Y2 is determined. This determination may occur in the second adaptor 40, the first adaptor 60, or the electric field generator 10. In the example shown in fig. 1, 50Y1 and 50Y2 are both determined as the C-shaped electrode sheet 50. The C-shaped electrode sheet 50 has 20 temperature sensors 53, and thus the C-shaped electrode sheet 50 contains 20 effective temperature signals, and 50Y1 and 50Y2 have 40 effective temperature signals.
In step 112, the tumor electric field therapy system 1000 determines whether any one of the 40 effective temperature signals collected by the second adaptor 40 is abnormal, and if so, the process goes to step 114. If all the 40 valid temperature signals are normal, go to step 113.
In step 113, the electric field generator 10 turns on the alternating electric signals Y1, Y2, turns off the alternating electric signals X1, X2 and proceeds to step 115.
In step 114, the tumor electric field treatment system 1000 alarms abnormally due to the effective temperature signals of the electrode plates 50Y1 and 50Y2, and then immediately proceeds to step 120.
In step 115, after the first adaptor 60 sends a temperature reading request to the 2 second adaptors 40 corresponding to the first connectors 25-X1 and the first connectors 25-X2, the temperature signals are read to acquire the temperatures corresponding to all the temperature sensors 53 on the electrode plates 50X1 and 50X 2. Step 116 is entered.
The above steps 110 and 115 are the same for the second adaptor 40, and the specific flow of steps 110 and 115 in the second adaptor 40 can refer to the flow 200.
In step 116, the tumor electric field therapy system 1000 determines the type of the electrode sheet 50X1 or 50X2 from the temperature signal, and then proceeds to step 117. This determination may occur in the second adaptor 40, the first adaptor 60, or the electric field generator 10. In the example shown in fig. 1, 50X1 and 50X2 are both determined as the C-shaped electrode sheet 50. The C-type electrode plate 50 has 20 temperature sensors 53, so the C-type electrode plate 50 contains 20 effective temperature signals, and 50X1 and 50X2 contain 40 effective temperature signals.
In step 117, the tumor electric field therapy system 1000 determines whether any one of the 40 effective temperature signals collected by the second adaptor 40 is abnormal, and if so, the process goes to step 114. If all 40 valid temperature signals are normal, go to step 118.
In step 118, the electric field generator 10 turns on the alternating electric signals X1, X2, turns off the alternating electric signals Y1, Y2 and proceeds to step 119. The total time from step 113, step 115, step 116, step 117 to step 118 is fixed, and the total time is 1s.
In step 119, the tumor electric field treatment system 1000 detects whether an electric field closing command sent by the user is received, and if so, proceeds to step 120; if the electric field closing command is not detected, step 121 is entered.
In step 120, the electric field of the electric tumor therapy system 1000 is turned off and the process proceeds to step 102. At which point the e-field treatment is finished waiting for the next on-field command.
In step 121, the tumor electric field treatment system 1000 determines whether the electric field parameters need to be adjusted according to the current electric field amplitude and the collected temperature signal, and if the electric field parameters need to be adjusted, the process goes to step 109; if the electric field parameters do not need to be adjusted, the process goes to step 110 to step 119 for circulation. The total time of step 118, step 119, step 121, step 110, step 111, step 112 to step 113 is fixed, and in the embodiment is 1s, so that the tumor electric field treatment system 1000 can realize the continuous output of the alternating electric signals in the X1 and X2 directions and the alternating electric signals in the Y1 and Y2 directions, which alternate with the period of 2 s. Meanwhile, the tumor electric field treatment system 1000 can reduce the time interval between the closing of the alternating electric signals X1 and X2 and the opening of the alternating electric signals Y1 and Y2 to 0s; the time interval between the closing of the alternating electric signals Y1 and Y2 and the opening of the alternating electric signals X1 and X2 is reduced to 0s, and the electric field treatment efficiency is improved on the premise of ensuring the temperature acquisition accuracy.
The temperature acquisition process 200 is shown in fig. 6, and the process can be applied to any temperature acquisition process of the second adaptor 40 adapted to the electrode pads 50X1, 50X2, 50Y1, 50Y2, where the second adaptor 40 connected to 50X1 is taken as an example.
In step 201, the second adaptor 40 is connected to the electrode sheet 50X1 and the first connector 60. Step 202 is entered.
In step 202, the second adaptor 40 determines whether a temperature reading request sent by the first adaptor 60 is received, and if the temperature reading request is received, step 204 is performed; if no temperature read request is received, step 202 is repeated.
In step 204, the first controller 45 of the second adaptor 40 controls the switch unit 44 to electrically connect the No. 1 wire of the second connector 31 to the GND of the second adaptor 40 and disconnect the No. 2, 3, and 4 wires (disconnect the No. 2, 3, and 4 wires from the GND). At this time, 5 temperature sensors 53 numbered 1 to 5 on the electrode sheet 50X1 are electrically connected to the resistor group 43 and GND, and 15 temperature sensors 53 numbered 6 to 20 are not electrically conducted.
In step 205, the ADC sampling unit 46 collects the temperature signals corresponding to the temperature sensors 53 coded as 1-5 on the filtered electrode slice 50X 1. The ADC sampling unit 46 collects the conductive analog temperature signals detected by the 5 temperature sensors 53 numbered 1 to 5 on the electrode slice 50X1 after filtering in the order of the sampling channels 1 to 5 and converts the signals into digital temperature signals, and then the process proceeds to step 206. During the time period for acquiring the temperature, the alternating electrical signal emitted by the electric field generator 10 is electrically connected to Y1, Y2, in the embodiment the voltage amplitude between Y1, Y2 is typically greater than 100Vpp. The alternating electrical signal generated by the electric field generator 10 is now electrically disconnected from X1, X2, but since the devices controlling the switching of the alternating electrical signal usually have certain parasitic parameters, when the alternating electrical signal is applied and X1, X2 are disconnected, X1, X2 still have a certain voltage amplitude, which in the example shown in fig. 1 is usually greater than 4Vpp. At this time, the residual alternating electrical signal between X1 and X2 is coupled to each module and conductive trace inside the second adaptor 40, which affects the temperature acquisition of the second adaptor 40 and generates a certain error, so that the filtering module 47 is required to attenuate the medium-high frequency signal in the analog temperature signal detected by the corresponding temperature sensor 53, and then the attenuated medium-high frequency signal is converted into a more accurate digital temperature signal by the ADC sampling unit 46.
In step 206, the first controller 45 of the second adaptor 40 controls the switch unit 44 to electrically connect the No. 2 wire of the second connector 31 to the GND of the second adaptor 40 and disconnect the No. 1, 3, and 4 wires (disconnect the No. 1, 3, and 4 wires from the GND). At this time, 5 temperature sensors 53 numbered 6 to 10 on the electrode sheet 50X1 are electrically connected to the resistor group 43 and GND, and 15 temperature sensors 53 numbered 1 to 5 and coded 11 to 20 are not electrically conducted. Step 207 is entered.
In step 207, the ADC sampling unit 46 collects the temperature signals corresponding to the temperature sensors 53 coded as 6-10 on the filtered electrode slice 50X 1. The ADC sampling unit 46 collects the conductive analog temperature signals detected by the 5 temperature sensors 53 numbered 6 to 10 on the electrode slice 50X1 after filtering in the order of the sampling channels 1 to 5 and converts the signals into digital temperature signals, and then the process proceeds to step 208.
In step 208, the first controller 45 of the second adaptor 40 controls the switching unit 44 to electrically connect the No. 3 wire of the second connector 31 to GND in the second adaptor 40 and disconnect the No. 1, 2, and 4 wires (disconnect the No. 1, 2, and 4 wires from GND). At this time, 5 temperature sensors 53 numbered 11 to 15 on the electrode sheet 50X1 are electrically connected to the resistor group 43 and GND, and 15 temperature sensors 53 numbered 1 to 10 and 16 to 20 are not electrically conducted. Step 209 is entered.
In step 209, the ADC sampling unit 46 collects the temperature signals corresponding to the temperature sensors 53 coded as 11-15 on the filtered electrode slice 50X 1. The ADC sampling unit 46 collects the conductive analog temperature signals detected by the 5 temperature sensors 53 numbered 11-15 on the electrode slice 50X1 after filtering in the order of the sampling channels 1-5 and converts the signals into digital temperature signals, and then the process proceeds to step 210.
In step 210, the first controller 45 of the second adaptor 40 controls the switch unit 44 to electrically connect the No. 4 wire in the second connector 31 to the GND in the second adaptor 40, and disconnect the No. 1, 2, and 3 wires (disconnect the No. 1, 2, and 3 wires from the GND). At this time, 5 temperature sensors 53 numbered 16 to 20 on the electrode sheet 50X1 are electrically connected to the resistor group 43 and GND, and 15 temperature sensors 53 numbered 1 to 15 are not electrically conducted. Step 211 is entered.
In step 211, the ADC sampling unit 46 collects temperature signals corresponding to the temperature sensors 53 encoded as 16-20 on the filtered electrode slice 50X 1. The ADC sampling unit 46 collects the conductive analog temperature signals detected by the 5 temperature sensors 53 encoded as 16-20 on the electrode slice 50X1 after filtering in the order of the sampling channels 1-5 and converts the signals into digital temperature signals, and then proceeds to step 212.
In step 212, the second adaptor 40 finishes the temperature acquisition, and the first controller 45 sends a temperature signal to the first adaptor 60 through the first communication unit 42 and then proceeds to step 202. The temperature signal in this step is a digital temperature signal converted by the ADC sampling unit 46. Alternatively, the transmitted temperature signal may include information about the type of the electrode sheet 50X 1.
In some embodiments, as shown in fig. 7, the electrode sheet 50 is a B-type electrode sheet 50 having 13 electrode units 51; as shown in fig. 8, the electrode sheet 50 is an a-type electrode sheet 50 having 9 electrode units 51.
In the example of fig. 1, the electrode sheets 50X1, 50X2, 50Y1, and 50Y2 may be used in any combination from a-type, B-type, and C-type electrode sheets 50. For example, B-type electrode sheets 50 are used for 50X1 and 50X2, and C-type electrode sheets 50 are used for 50Y1 and 50Y2.
The temperature acquisition process 200 for the B-type electrode plate 50 in this embodiment is the same as the process for the C-type electrode plate 50 in embodiment 1, but in step 209 of the temperature acquisition process 200, the analog temperature signals acquired by the sampling channels 4 and 5 of the ADC sampling unit 46 are close to the analog signals of the VCC power supply voltage value, because No. 4, 5, 9, or 10 wires on the electrode plate 50 electrically connected to the sampling channels 4 and 5 are electrically connected to GND. Similarly, in step 211 of the temperature acquisition process 200, the analog temperature signals acquired by the sampling channels 1 to 5 of the ADC sampling unit 46 are all close to the analog signal of the VCC power supply voltage value, because the wires 1 to 13 on the electrode plate 50 electrically connected to the sampling channels 1 to 5 are not electrically connected to the GND. Therefore, in step 212, the temperature signal transmitted by the second adaptor 40 includes digital temperature signals corresponding to 13 temperature sensors 53 of 1-13 on the electrode slice 50 and digital temperature signals converted from analog signals close to the VCC supply voltage value of 7 non-provided temperature sensors 53 of 14-20. These 7 digital temperature signals, converted from analog signals close to the value of the VCC supply voltage, are the interference temperature data.
The process 100 of the tumor electric field treatment system 1000 for the B-type electrode plate 50 in this embodiment is the same as the process for the C-type electrode plate 50 shown in fig. 1. Taking the B-type electrode plate 50X1 as an example, in step 116, the analog temperature signals corresponding to 7 non-installed temperature sensors 53 numbered 14-20 in the temperature signals are all close to the analog signal of the VCC power supply voltage value. The first adapter 60 can determine that 50X1 is the B-type electrode plate according to the above. Alternatively, the determination process may occur in the second adaptor 40. When processing the temperature signals, the tumor electric field treatment system 1000 can eliminate the temperature signals corresponding to 7 non-temperature sensors 53 with numbers of 14-20 and then perform data processing. For example, in a system in which the B-type electrode sheet 50 is used for the electrode sheets 50X1 and 50X2, and the C-type electrode sheet 50 is used for the electrode sheets 50Y1 and 50Y2, the tumor electric field treatment system 1000 may determine that the electrode sheets 50Y1 and 50Y2 are both the C-type electrode sheets 50 in step 111, 40 temperature signals are effective temperature data, and determine whether there is an abnormality in the 40 effective temperature data in step 112; in step 116, it is determined that both of the electrode sheets 50X1 and 50X2 are B-type electrode sheets 50, and therefore, the temperature signals of 13 temperature sensors 53, which are numbered 1 to 13, respectively, corresponding to the electrode sheets 50X1 and 50X2 are effective temperature data, and the electrode sheets 50X1 and 50X2 have 26 effective temperature data, and it is determined whether there is an abnormality in step 117 for the 26 effective temperature data.
The temperature acquisition process 200 for the a-type electrode plate 50 in this embodiment is identical to the process for the C-type electrode plate 50 in embodiment 1, but the analog temperature signal acquired by the sampling channel 5 of the ADC sampling unit 46 in step 207 is close to the analog signal of the VCC supply voltage value, because the No. 10 wire on the electrode plate 50 electrically connected to the sampling channel 5 is not electrically connected to GND. Similarly, in step 209, the analog temperature signals collected by the sampling channels 1 to 5 of the ADC sampling unit 46 are all close to the analog signals of the VCC power supply voltage value, because No. 3, no. 6, no. 7, no. 8, no. 9, no. 10 wires on the electrode plate 50 electrically connected to the sampling channels 1 to 5 are not electrically connected to GND. In step 211, the analog temperature signals collected by the sampling channels 1 to 5 of the ADC sampling unit 46 are all close to the analog signals of the VCC supply voltage value, because No. 6, no. 7, no. 8, no. 9, no. 10 wires on the electrode plate 50 electrically connected to the sampling channels 1 to 5 are not electrically connected to GND. Therefore, in step 212, the temperature signals transmitted by the second adaptor 40 include digital temperature signals corresponding to 9 temperature sensors 53 numbered 1-9 on the electrode pad 50 and digital temperature signals corresponding to 11 non-set temperature sensors 53 numbered 10-20 converted from analog signals close to the VCC power supply voltage value.
The process 100 of the tumor electric field treatment system 1000 for the a-type electrode plate 50 in this embodiment is the same as the process for the C-type electrode plate 50 in embodiment 1. Taking the a-type electrode plate 50X1 as an example, the analog temperature signals corresponding to 11 non-installed temperature sensors 53 numbered 10-20 in the temperature signals in step 116 are all close to the analog signal of the VCC power supply voltage value. The first adaptor 60 can determine that 50X1 is the a-type electrode plate according to the above. Alternatively, the determination process may occur in the second adaptor 40. When processing the signals, the tumor electric field treatment system 1000 can eliminate the temperature signals corresponding to the numbers 10-20 and then process the signals. For example, for a system using the a-type electrode slice 50 for 50X1 and 50X2 and the C-type electrode slice 50 for 50Y1 and 50Y2, the tumor electric field treatment system 1000 may determine that 50Y1 and 50Y2 are both the C-type electrode slices 50 in step 111, 40 temperature signals are both effective temperature data, and determine whether there is an abnormality in 40 effective temperature data in step 112; since it is determined in step 116 that both 50X1 and 50X2 are the a-type electrode sheet 50, the temperature signals of channels 1 to 9 corresponding to 50X1 and 50X2 are effective temperature data, which is 18 effective temperature data, and it is determined in step 117 whether there is an abnormality in the 18 effective temperature data.
Thus, the a-type, B-type and C-type electrode plates 50 can be combined without changing the flow of the electric field generator 10, the first adapter 60, the second adapter 40 and the tumor electric field treatment system 1000, and the electric field treatment efficiency can be improved without affecting the flexibility of the electrode cables.
In the above embodiment, by adopting the matrix network temperature detection technology and matching with the corresponding electric field control algorithm, temperature detection and electric field control are further performed, so that not only can the coverage rate of the temperature sensor 53 be effectively increased under the condition of controlling the number of cable cores, the excessive load of the electrode plate 30 be avoided, and the pasting effect of the electrode plate 30 be maintained, but also the advantages of flexible combination of the electrode plates 30, accurate identification of the electrode plates 30 and small electric field turn-off interval are achieved, so that the compliance of a patient can be improved, and the treatment effect of the patient can be improved; meanwhile, whether the corresponding pair of electrode sheets 50 close the electric field or adjust the electric field parameter may be controlled based on the detected temperature.
The present invention also provides a tumor treatment apparatus comprising: at least one pair of electrode plates 50 as described above, or the tumor electric field treatment system 1000 as described above.
According to the tumor treatment equipment provided by the embodiment of the invention, the electrode plate 50 or the tumor electric field treatment system 1000 can ensure that the coverage rate of the temperature sensor 53 reaches 100% under the condition of controlling the number of cable cores, so that the phenomenon that the load of the electrode plate 50 is too large is avoided, and the application effect of the electrode plate 50 is kept.
The present invention further provides a computer readable storage medium (not shown) having a temperature detection program of the tumor electric field treatment system 1000 stored thereon, wherein when the temperature detection program of the tumor electric field treatment system 1000 is executed by a processor (not shown), the method for identifying electrode slices of the tumor electric field treatment system 1000 is implemented.
According to the computer-readable storage medium of the embodiment of the invention, by the temperature detection method of the tumor electric field treatment system 1000, the coverage rate of the temperature sensor 53 can be effectively increased under the condition of controlling the number of cable cores, the overlarge load of the electrode plate 50 is avoided, and the application effect of the electrode plate 50 is maintained.
The present invention further provides a first adapter 60 of the tumor electric field treatment system 1000, which comprises a memory (not shown), a processor (not shown) and a temperature detection program of the tumor electric field treatment system 1000 stored in the memory (not shown) and capable of running on the processor (not shown), wherein when the processor executes the temperature detection program of the tumor electric field treatment system 1000, the temperature detection method of the tumor electric field treatment system 1000 is realized.
According to the first adapter 60 of the tumor electric field treatment system 1000 of the embodiment of the invention, by the temperature detection method of the tumor electric field treatment system 1000, the coverage rate of the temperature sensor 53 can be effectively increased under the condition of controlling the number of cable cores, the overlarge load of the electrode plate is avoided, and the application effect of the electrode plate is maintained.
The present invention further provides a second adaptor 40 of the tumor electric field treatment system 1000, which comprises a memory (not shown), a processor (not shown) and a temperature detection program of the tumor electric field treatment system 1000 stored in the memory (not shown) and operable on the processor (not shown), wherein when the processor executes the temperature detection program of the tumor electric field treatment system 1000, the aforementioned temperature detection method of the tumor electric field treatment system 1000 is realized.
According to the second adapter 40 of the tumor electric field treatment system 1000 of the embodiment of the invention, by the temperature detection method of the tumor electric field treatment system 1000, the coverage rate of the temperature sensor 53 can be effectively increased under the condition of controlling the number of cable cores, the load of the electrode plate 50 is prevented from being too large, and the application effect of the electrode plate 50 is maintained.
The present invention further provides an electric field generator 10 of the tumor electric field treatment system 1000, which comprises a memory (not shown), a processor (not shown) and a temperature detection program of the tumor electric field treatment system 1000 stored in the memory (not shown) and operable on the processor (not shown), wherein when the processor (not shown) executes the temperature detection program of the tumor electric field treatment system 1000, the aforementioned temperature detection method of the tumor electric field treatment system 1000 is implemented.
It should be noted that the logic and/or steps represented in the flowcharts or otherwise described herein, such as an ordered listing of executable instructions that can be considered to implement logical functions, can be embodied in any computer-readable medium for use by or in connection with an instruction execution system, apparatus, or device, such as a computer-based system, processor-containing system, or other system that can fetch the instructions from the instruction execution system, apparatus, or device and execute the instructions. For the purposes of this description, a "computer-readable medium" can be any means that can contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device. More specific examples (a non-exhaustive list) of the computer-readable medium would include the following: an electrical connection (electronic device) having one or more wires, a portable computer diskette (magnetic device), a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber device, and a portable compact disc read-only memory (CDROM). Additionally, the computer-readable medium could even be paper or another suitable medium upon which the program is printed, as the program can be electronically captured, via for instance optical scanning of the paper or other medium, then compiled, interpreted or otherwise processed in a suitable manner if necessary, and then stored in a computer memory.
It should be understood that portions of the present invention may be implemented in hardware, software, firmware, or a combination thereof. In the above embodiments, the various steps or methods may be implemented in software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, any one or combination of the following techniques, which are known in the art, may be used: a discrete logic circuit having a logic gate circuit for implementing a logic function on a data signal, an application specific integrated circuit having an appropriate combinational logic gate circuit, a Programmable Gate Array (PGA), a Field Programmable Gate Array (FPGA), or the like.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
Furthermore, the terms "first", "second", and the like used in the embodiments of the present invention are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated in the embodiments. Thus, a feature of an embodiment of the present invention that is defined by the terms "first," "second," etc. may explicitly or implicitly indicate that at least one of the feature is included in the embodiment. In the description of the present invention, the word "plurality" means at least two or two and more, such as two, three, four, etc., unless specifically limited otherwise in the examples.
In the present invention, unless otherwise explicitly specified or limited in relation to the embodiments, the terms "mounted," "connected," and "fixed" in the embodiments shall be understood in a broad sense, for example, the connection may be a fixed connection, a detachable connection, or an integrated body, and may be understood as a mechanical connection, an electrical connection, etc.; of course, they may be directly connected or indirectly connected through intervening media, or they may be interconnected within one another or in an interactive relationship. Those of ordinary skill in the art will understand the specific meaning of the above terms in the present invention according to their specific implementation.
In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
Although embodiments of the present invention have been shown and described above, it will be understood that the above embodiments are exemplary and not to be construed as limiting the present invention, and that changes, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.

Claims (35)

1. An electrode patch for an electric field tumor treatment system, comprising:
a substrate;
a plurality of electrode sheet units and a plurality of temperature detection units, each of which is disposed on the substrate, each of the electrode sheet units being capable of applying an alternating electric field, the plurality of temperature detection units being disposed in one-to-one correspondence with the plurality of electrode sheet units to detect a temperature at each of the electrode sheet units, wherein,
the plurality of electrode sheet units are configured into at least three row groups and at least three column groups;
the signal ends of the corresponding temperature detection units in each column group are connected together to serve as temperature sampling points, and the grounding ends of the corresponding temperature detection units in each row group are connected to the grounding pins through the switch units;
the electrode plate comprises a plurality of electrode plates, a handshaking chip arranged on the substrate, wherein the handshaking chip is suitable for performing handshaking communication with external equipment to judge the connection state of the electrode plates, and after the handshaking communication between the handshaking chip and the external equipment is completed, the switching state of the switching unit is configured so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled by corresponding temperature sampling points.
2. The electrode sheet according to claim 1, wherein the sampled temperature signal detected by each temperature detection unit is used for characterizing the type of the electrode sheet.
3. The electrode patch according to claim 1, characterized in that the ground pin of the handshake chip is connected to the ground pin through the switch unit, and the communication pin of the handshake chip is connected to the adaptor unit of the tumor electric field treatment system through a communication line.
4. The electrode pad of claim 3, wherein the handshaking chip is powered by an external energy storage element to store energy when the communication line is transmitting a high level and to discharge energy when the communication line is transmitting a low level.
5. The electrode sheet of claim 4, wherein the energy storage element is a capacitor.
6. The electrode sheet according to any one of claims 1 to 5, wherein each of the temperature detection units includes a temperature sensor and a diode having an anode and a cathode, the anode of the diode being connected to the temperature sensor, and the cathode of the diode being a ground terminal of the temperature detection unit.
7. The electrode sheet of claim 1, wherein each temperature sampling point is connected to a direct current power supply through a corresponding voltage dividing resistor.
8. The electrode sheet according to claim 7, wherein the voltage-dividing resistor and the switch unit are both disposed outside the substrate.
9. The electrode sheet according to claim 1, wherein the sampled temperature signal detected by each temperature detection unit is also used for representing whether the electrode sheet has temperature abnormality.
10. An electric field tumor treatment system, comprising:
at least one pair of electrode sheets according to any one of claims 1-9;
adapter unit and electric field generator, electric field generator is used for producing alternating electrical signal, and passes through the adapter unit will alternating electrical signal transmits for every the electrode slice, the adapter unit be used for with the chip of shaking hands carries out the communication of shaking hands, and disposes after accomplishing the communication of shaking hands the on off state of switch unit is with through corresponding temperature sampling point simultaneously to every the temperature signal that corresponds the temperature detecting element detection in the group of going samples.
11. The system of claim 10, wherein the adapter unit comprises a first adapter and at least one pair of second adapters, the second adapters being adapted to connect to corresponding electrode pads, the first adapter being adapted to connect each of the second adapters to the electric field generator.
12. The electric field tumor therapy system according to claim 11, wherein the second adapter comprises a first controller and an ADC sampling unit, the first controller is configured to configure a switching state of the switching unit when receiving a handshake signal sent by the electric field generator, so as to power up the handshake chip, send the handshake signal to the handshake chip, determine whether handshake communication with the handshake chip is completed according to a feedback signal of the handshake chip, and configure the switching state of the switching unit after the handshake communication is completed, so that the ADC sampling unit simultaneously samples the temperature signal detected by the corresponding temperature detection unit in each row group through the corresponding temperature sampling points, thereby obtaining a plurality of AD sampling values.
13. The oncology electric field treatment system of claim 12, wherein the first controller is further configured to identify a type of a respective electrode patch from the number of AD samples.
14. The electric field tumor therapy system according to claim 12, wherein the first controller is further configured to determine whether the temperature abnormality occurs in the corresponding electrode pad according to the AD samples during the process of transmitting the alternating electric signal from the electric field generator to the corresponding electrode pad.
15. The electric field tumor therapy system according to claim 12, wherein the second adapter further comprises a filtering unit disposed between the ADC sampling unit and the corresponding temperature sampling point, the filtering unit being configured to filter the temperature signal detected by each temperature detecting unit.
16. The electric field tumor therapy system according to claim 12, wherein the second adapter further comprises a first communication unit, the first adapter comprises a second communication unit and a second controller, the second communication unit is connected to the first communication unit, wherein the first controller is further configured to send the feedback signal of the handshake chip to the second controller, so that the second controller determines whether the first controller and the handshake chip complete handshake communication according to the feedback signal of the handshake chip.
17. The system of claim 16, wherein the first controller is further configured to send the plurality of AD samples to the second controller such that the second controller identifies a type of the corresponding electrode patch based on the plurality of AD samples.
18. The electrical field tumor therapy system according to claim 17, wherein the second controller is further configured to determine whether the temperature abnormality occurs in the corresponding electrode pad according to the AD samples during the process of transmitting the alternating electrical signal from the electrical field generator to the corresponding electrode pad.
19. The electric field tumor therapy system according to claim 16, wherein the first adaptor further comprises a third communication unit, the third communication unit is connected to the second controller and the electric field generator, respectively, and the first controller is further configured to send the feedback signal of the handshake chip to the electric field generator through the first adaptor, so that the electric field generator can determine whether the handshake communication between the first controller and the handshake chip is completed according to the feedback signal of the handshake chip.
20. The system of claim 19, wherein the first controller is further configured to send the plurality of AD samples to the electric field generator via the first adapter such that the electric field generator identifies the type of the corresponding electrode patch based on the plurality of AD samples.
21. The electrical field tumor therapy system according to claim 20, wherein the electrical field generator is further configured to determine whether the temperature abnormality occurs in the corresponding electrode pad according to the AD samples during the transmission of the alternating electrical signal to the corresponding electrode pad.
22. The electrical field tumor therapy system according to any one of claims 11-21, further comprising:
at least one first connector, each said first connector adapted to connect a respective second adapter to said first adapter;
at least one second connector, each said second connector adapted to connect a respective electrode pad to a corresponding second adaptor;
a third connector adapted to connect the electric field generator to the first adaptor.
23. The system of claim 22, wherein the first connector is configured to connect the second adapter to the first adapter in the form of a socket connector, the second connector is configured to connect the second adapter to the electrode pad in the form of a socket connector, and the third connector is configured to connect the first adapter to the electric field generator in the form of a socket connector.
24. The electric field tumor therapy system according to any one of claims 10-21, wherein the number of electrode pads is 4.
25. A tumor treatment apparatus, comprising: at least one pair of electrode patches according to any one of claims 1-9, or a tumor electric field treatment system according to any one of claims 10-24.
26. A method for detecting temperature of a tumor electric field treatment system, wherein the tumor electric field treatment system comprises the electrode sheet, the electric field generator and the adapter unit according to any one of claims 1 to 9, the method comprising:
performing handshake communication with the handshake chip through the adapter unit to judge the connection state of the corresponding electrode slice;
and when each electrode plate is successfully connected with the adapter unit, the switch state of the switch unit is configured through the adapter unit, so that the temperature signals detected by the corresponding temperature detection units in each row group are simultaneously sampled through the corresponding temperature sampling points.
27. The method of claim 26, further comprising: and identifying the type of the corresponding electrode plate according to the sampled temperature signal detected by each temperature detection unit.
28. The method according to claim 27, wherein identifying the type of the corresponding electrode sheet according to the sampled temperature signal detected by each temperature detection unit comprises the following steps:
acquiring a plurality of AD sampling values according to the sampled temperature signal detected by each temperature detection unit;
and determining the number of electrode plate units of the corresponding electrode plate according to the AD sampling values, and determining the type of the corresponding electrode plate according to the number of the electrode plate units.
29. The method of any of claims 26-28, wherein prior to performing handshake communication with the handshake chip via the adaptor unit, the method further comprises: and configuring the switch state of the switch unit through the adapter unit so as to electrify the handshake chip for work.
30. The method of claim 27, wherein during the transmission of the alternating electrical signal by the electric field generator to the respective electrode sheet, the method further comprises: and judging whether the temperature of the corresponding electrode plate is abnormal or not according to the plurality of AD sampling values.
31. The method of claim 27, wherein during the transmission of the alternating electrical signal by the electric field generator to the respective electrode sheet, the method further comprises: and adjusting the parameters of the alternating electric signal according to a plurality of AD sampling values.
32. A computer-readable storage medium, wherein a temperature detection program of a tumor electric field treatment system is stored thereon, and when the temperature detection program of the tumor electric field treatment system is executed by a processor, the method for identifying electrode slices of the tumor electric field treatment system according to any one of claims 26 to 31 is implemented.
33. A first adapter of a tumor electric field treatment system, comprising a memory, a processor and a temperature detection program of the tumor electric field treatment system stored in the memory and operable on the processor, wherein the processor implements the temperature detection method of the tumor electric field treatment system according to any one of claims 26-31 when executing the temperature detection program of the tumor electric field treatment system.
34. A second adaptor of the electric field tumor therapy system, comprising a memory, a processor and a temperature detection program of the electric field tumor therapy system, wherein the temperature detection program of the electric field tumor therapy system is stored in the memory and can be run on the processor, and when the processor executes the temperature detection program of the electric field tumor therapy system, the temperature detection method of the electric field tumor therapy system according to any one of claims 26 to 31 is implemented.
35. An electric field generator of a tumor electric field treatment system, comprising a memory, a processor and a temperature detection program of the tumor electric field treatment system stored in the memory and operable on the processor, wherein the processor implements the temperature detection program of the tumor electric field treatment system to realize the temperature detection method of the tumor electric field treatment system according to any one of claims 26-31.
CN202211722158.0A 2022-10-27 2022-12-30 Tumor electric field treatment system, electrode plate thereof and temperature detection method Active CN115845260B (en)

Priority Applications (3)

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CN202211722158.0A CN115845260B (en) 2022-12-30 Tumor electric field treatment system, electrode plate thereof and temperature detection method
PCT/CN2023/127360 WO2024088418A1 (en) 2022-10-27 2023-10-27 Electrode sheet, electric field treating system, and control method
PCT/CN2023/141647 WO2024131987A1 (en) 2022-12-23 2023-12-25 Tumor electric field treatment system and device, control and manufacturing method, detection method, and computer-readable storage medium

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Application Number Priority Date Filing Date Title
CN202211722158.0A CN115845260B (en) 2022-12-30 Tumor electric field treatment system, electrode plate thereof and temperature detection method

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CN115845260B CN115845260B (en) 2024-07-05

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