CN115920230A

CN115920230A - Electrode plate, electric field treatment system and control method

Info

Publication number: CN115920230A
Application number: CN202211723961.6A
Authority: CN
Inventors: 应建俊; 沈琪超; 惠嘉杰; 陈晟; 于晶; 张军
Original assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Current assignee: Jiangsu Hailai Xinchuang Medical Technology Co Ltd
Priority date: 2022-12-30
Filing date: 2022-12-30
Publication date: 2023-04-07

Abstract

An electrode plate, an electric field treatment system and a control method. The electrode plate provided by the invention comprises a plurality of dielectric elements, a plurality of temperature detectors which are respectively arranged in one-to-one correspondence with the dielectric elements and used for monitoring the temperature of the corresponding part in real time and outputting detection signals, and a flexible circuit board which is internally embedded with one path of AC signal line, a plurality of paths of grounding lines and a plurality of paths of signal output lines, wherein the AC signal line is electrically connected with all the dielectric elements and transmits AC signals to all the dielectric elements; each temperature detector and a corresponding dielectric element form an electrode unit, the electrode units are divided into different groups, and the total number of the grounding wires and the signal output wires is less than that of the temperature detectors. Each dielectric element of the invention is provided with a corresponding temperature detector, so that the temperature detection is more comprehensive and accurate.

Description

Electrode plate, electric field treatment system and control method

Technical Field

The invention relates to the field of medical instruments, in particular to an electrode plate for tumor electric field treatment, an electric field treatment system and a control method.

Background

At present, the treatment modes of tumors mainly comprise operations, radiotherapy, chemotherapy and the like, but the methods have corresponding defects, for example, radiotherapy and chemotherapy can generate side effects and kill normal cells. The electric field treatment of tumor is one of the current development fronts, and is a tumor treatment method which uses an electric field generator to generate an alternating electric field with low intensity and medium-high frequency to interfere the mitosis process of tumor cells. Research shows that the electric field treatment has obvious effect in treating diseases such as glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and the like, and the electric field applied by the treatment method can influence the aggregation of tubulin, prevent spindle formation, inhibit mitosis progress and induce cancer cell apoptosis.

The existing tumor electric field treatment system mainly comprises an electric field generating device for generating alternating electric signals for tumor electric field treatment, an adapter electrically connected with the electric field generating device, and a plurality of pairs of electrode plates electrically connected with the electric field generating device through the adapter. The electric field generating device transmits alternating electric signals for tumor electric field treatment to each electrode plate through the adapter, and then the alternating electric fields are applied to the tumor parts of the patients through the electrode plates to carry out the tumor electric field treatment. When the tumor treatment electric field is applied to the body of a patient, heat is collected at the corresponding position where the electrode is attached to the skin, so that the temperature of the body surface corresponding to the tumor part of the patient to which the electrode is attached is monitored in real time. When the body surface temperature is too high, the electric field intensity needs to be adjusted in time, and the skin of the patient needs to be prevented from being scalded by low temperature due to too high temperature.

Each electrode sheet is provided with a plurality of electrode units. In the conventional electrode sheet, a thermistor element is disposed on some electrode units corresponding to a part of the electrode sheet, and each thermistor element is connected in parallel with each other. The resistance value of the thermistor element changes with temperature changes, and the change of the resistance value of the thermistor element corresponds to the temperature change of the body surface to which the electrode unit is attached. Each electrode plate is provided with 8 thermistor elements, and a cable provided with 10-core wires is connected between each electrode plate and the adapter. Each electrode piece transmits the resistance values of 8 thermistor elements through a cable of 10-core wires. Namely, a cable of 10-core wire includes 8 signal output lines for transmitting a temperature signal sensed by the thermistor element to the adaptor, and further includes 1 ground line connected to each thermistor element and 1 AC signal line connected to each electrode unit. No matter how many electrode units are on the electrode plates, the number of thermistor elements on the electrode plates is not more than 8, and the electrode plates are connected with the adapter through cables configured by 10-core wires. For example, if 8 thermistor elements are disposed on an electrode sheet having 9 electrode units, 8 independent wires are required to transmit signals of the 8 thermistor elements, and the coverage of the thermistor elements in the electrode sheet is 89% (8/9 = 0.89). For another example, if 8 thermistor elements are provided in an electrode sheet having 13 electrode units, the coverage of the thermistor elements in the electrode sheet is 62% (8/13 = 0.62). If only 8 thermosensitive dielectric elements are distributed on 8 electrode units in 20 electrode units on an electrode sheet with 20 electrode units, and 12 electrode units do not cover the thermosensitive resistor elements, the temperature of more than half of the electrode units cannot be monitored, and the condition that the skin of a patient is scalded at low temperature due to incomplete monitoring is easy to occur.

Accordingly, there is a need for an improved electrode patch, an electric field treatment system and a control method thereof, which can comprehensively monitor the temperature of the surface of the patient to which each electrode unit of the electrode patch is correspondingly attached.

Disclosure of Invention

The invention provides an electrode plate with a simplified circuit structure and comprehensive and accurate temperature monitoring, an electric field treatment system and a control method thereof.

The electrode slice is realized by the following technical scheme: an electrode sheet, comprising: a plurality of dielectric elements configured to apply an alternating electric field to a tumor site of a patient; a plurality of temperature detectors, which are respectively arranged in one-to-one correspondence with the plurality of dielectric elements and are configured to monitor the temperature of the body surface corresponding to the tumor part of the patient in real time and output detection signals, wherein each temperature detector is provided with a grounding end and a signal end; the flexible circuit board is provided with a plurality of dielectric elements and a plurality of temperature sensors at intervals, and one path of AC signal line, a plurality of paths of grounding lines and a plurality of paths of signal output lines are embedded in the flexible circuit board, wherein the one path of AC signal line is configured to be electrically connected with all the dielectric elements arranged on the flexible circuit board and transmit AC signals to all the dielectric elements, the grounding lines are used for short-circuiting and grounding ends of all the temperature detectors, and the signal output lines are used for connecting signal ends of all the temperature detectors in parallel and transmitting detection signals of the temperature detectors; each temperature detector and one corresponding dielectric element form an electrode unit, the plurality of temperature sensors and the plurality of dielectric elements form a plurality of electrode units, the plurality of electrode units are divided into different groups, each group at least comprises one electrode unit, and the total number of the grounding wires and the signal output wires is less than the number of the temperature detectors.

Further, the number of the grounding wires is related to the number of groups into which the plurality of electrode units are grouped, and the number of the signal output wires is related to the number of the electrode units in each group in different groups.

Further, the number of the ground lines is equal to the number of groups into which the plurality of electrode units are grouped, and the number of the signal output lines is related to the number of electrode units of a group having the largest number of electrode units.

Further, the number of the signal output lines is equal to the total number of the electrode units in a group of the electrode units with the most electrode units.

Furthermore, the grounding ends of the temperature detectors of the electrode units in the same group are all in short circuit grounding with the same grounding line, and the signal ends of the temperature detectors of the electrode units in the same group are respectively connected with signal output lines which correspond to the signal ends and are different from each other.

Furthermore, the grounding ends of the temperature detectors of the different groups of corresponding electrode units are respectively in short circuit with the corresponding grounding wires which are different from each other, and the signal ends of the temperature detectors of the different groups of corresponding electrode units are connected to the same signal output line in parallel.

Furthermore, the grounding ends of the temperature detectors of the different groups of the electrode units which are not corresponding are respectively in short circuit with a path of grounding wire which is corresponding to the electrode units and is different from the grounding wire, and the signal ends of the temperature detectors of the different groups of the electrode units which are not corresponding are respectively connected with a path of signal output wire which is corresponding to the electrode units and is different from the signal output wire.

Furthermore, only one path of the grounding wires of the multiple paths of grounding wires is connected at the same time, and the rest paths of the grounding wires are disconnected.

Furthermore, the detection signals of the temperature detectors of the electrode units in the same group are collected and transmitted when one of the grounding wires electrically connected with the grounding ends of the temperature detectors of the electrode units in the group is conducted.

Furthermore, detection signals of the temperature detectors of the electrode units in different groups are collected and transmitted in a time-sharing mode when multiple grounding wires are sequentially conducted.

Furthermore, still include one with flexible line way board electric connection's first cable, first cable have with flexible line way board inside inlay establish one way AC signal line, multichannel earth connection and multichannel signal output line respectively one-to-one electrical connection's multicore wire.

Further, each dielectric element has a through hole penetrating therethrough for receiving a corresponding temperature sensor.

Further, each of the electrode units further includes a diode connected in series with the temperature detector.

The electric field treatment system is realized by the following technical scheme: an electric field therapy system comprising: at least one of the electrode sheets; an electric field generator configured to apply alternating current signals to the plurality of dielectric elements of the electrode sheet via the AC signal lines of the electrode sheet; and an adaptor connected between the electrode sheet and the electric field generator, configured to transmit the alternating current signal generated by the electric field generator to the AC signal line of the electrode sheet, and further configured to receive the detection signal output by the multiplexed signal output lines of the electrode sheet.

Further, the adapter comprises a plurality of groups of switches, each group of switches comprises a plurality of switches, the plurality of switches are respectively and electrically connected with the plurality of grounding wires of the corresponding electrode slice one by one, and the plurality of switches are configured to control the plurality of grounding wires of the corresponding electrode slice to be connected or disconnected.

Further, the adapter further comprises a controller connected with the plurality of groups of switches, and the controller sequentially and circularly controls the on-off state of each switch in the plurality of groups of switches to sequentially and independently conduct each grounding line in the plurality of grounding lines of the corresponding electrode plate.

Furthermore, the adaptor further comprises a plurality of groups of analog-to-digital converters electrically connected to the multiple signal output lines of the plurality of electrode plates one by one, and each group of analog-to-digital converters is configured to receive the detection signal transmitted by the multiple signal output lines of the corresponding electrode plate and convert the detection signal from an analog signal to a digital signal.

Further, the adaptor further comprises a communication transceiver configured to acquire the digital signal output by each set of the analog-to-digital converters and transmit the digital signal to the electric field generator.

Further, the electric field generator is also configured to adjust an alternating current signal applied to dielectric elements of electrode units of the respective electrode sheet according to the received digital signal.

Further, the communication transceiver is controlled by the controller and serially transmits the digital signal converted by the analog-to-digital converter.

The flexible circuit board is provided with a plurality of first connectors, each first connector is configured to connect a corresponding electrode plate to the adapter, and each first connector is arranged at one end, away from the flexible circuit board, of a first cable of the corresponding electrode plate.

Furthermore, each group of analog-to-digital converters comprises a plurality of detection channels, and each detection channel is connected with one corresponding signal output line in the plurality of signal output lines.

Further, a second connector is included for connecting the adaptor to the electric field generator.

Further, a second cable for connecting the adaptor and the second connector is also included.

The control method of the electric field treatment system is realized by the following scheme: a method of controlling an electric field therapy system as described above, comprising: and sequentially and independently conducting each ground wire in the multiple ground wires of the electrode slice, and acquiring a detection signal of the temperature detector of each electrode unit in a group of electrode units which are grounded by the ground wires and received by the adapter in the conducting state of each ground wire.

Further, the adaptor includes a plurality of sets of switches, each set of switches includes a plurality of switches, the plurality of switches are respectively and electrically connected to the plurality of paths of the grounding wires of the corresponding electrode sheet one by one and configured to control on/off of the plurality of paths of the grounding wires, and sequentially and individually turning on each path of the grounding wires of the plurality of paths of the electrode sheets is achieved by sequentially and individually closing each switch of the plurality of switches.

Further, the adaptor further comprises a plurality of groups of analog-to-digital converters, each group of analog-to-digital converters is connected with the multi-path signal output line of the corresponding electrode plate and is configured to receive the detection signal transmitted by the multi-path signal output line of the corresponding electrode plate and convert the detection signal from an analog signal to a digital signal.

Further, the method also comprises the following steps: the digital signal is serially transmitted to the electric field generator.

Further, the method also comprises the following steps: and comparing the set preset temperature threshold with all the digital signals and adjusting the alternating current signals applied to the dielectric elements of the electrode units of the corresponding electrode plates according to the comparison result.

Each electrode unit of the electrode plate comprises a temperature detector, the grounding ends of the temperature detectors of all electrode units in each group are grounded in a short circuit mode through the same grounding wire, and the signal ends of the temperature detectors of all electrode units in each group are respectively connected with one signal output wire which corresponds to the signal ends of the temperature detectors of all electrode units in each group and is different from the signal output wires in parallel, so that detection signals of all temperature detectors of all electrode units in each group can be collected and transmitted at the same time when the detection signals of all temperature detectors of all electrode units in each group are conducted with the same grounding wire which is in short circuit with the grounding ends of all temperature detectors of all electrode units in the group; the detection signals of all the temperature detectors of the electrode plate can be collected and transmitted by sequentially conducting different ground wires, so that the body surface temperature of a patient can be detected more comprehensively and accurately, the total number of the ground wires and the signal output wires is less than that of the temperature detectors, the wiring design of the flexible circuit board can be simplified, and the manufacturing cost can be reduced.

These and other aspects of the disclosure will be apparent from and elucidated with reference to the embodiments described hereinafter.

Drawings

FIG. 1 is a schematic block diagram of an electric field treatment system according to the present invention;

FIG. 2 is a schematic block diagram of one of the electrode pads and adapters shown in FIG. 1;

FIG. 3 is a schematic block diagram of an electrode pad and adapter in an electric field treatment system in accordance with another embodiment of the present invention;

FIG. 4 is a schematic block diagram of the internal structure of the adapter shown in FIG. 1;

figure 5 is a flow chart of a method of controlling an electric field treatment system in accordance with one embodiment of the present invention.

Detailed Description

Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with the present application. Rather, they are merely examples of electrode pads, electric field treatment systems, and control methods consistent with certain aspects of the present application, as detailed in the appended claims.

Figure 1 shows an electric field treatment system 1 of the present invention. As shown in fig. 1, an electric field treatment system 1 includes: at least one pair of electrode sheets 10, an adaptor 20 connected to the electrode sheets 10, and an electric field generator 30 connected to the adaptor 20. The electric field generator 30 supplies an alternating current signal to the electrode sheet 10 so that the electrode sheet 10 generates a therapeutic electric field. The adaptor 20 is electrically connected between the electrode plate 10 and the electric field generator 30, and is used for transmitting the alternating current signal generated by the electric field generator 30 to the electrode plate 10. That is, the electric field generator 30 can generate an ac signal, and the generated ac signal is transmitted to each electrode plate 10 through the adaptor 20, so that a therapeutic electric field for treating tumor is generated between the same pair of electrode plates 10. As shown in fig. 1, in the present embodiment, the number of electrode sheets 10 is 4. Each electrode sheet 10 includes a plurality of dielectric elements 13 of the same number, and each dielectric element 13 is electrically connected to the adaptor 20. The number of electrode units on each electrode sheet 10 is 20. In other embodiments, the electric field treatment system 1 may also have more or fewer electrode pads 10. In other embodiments, each pair of electrode sheets 10 has the same number of dielectric elements 13, and different pairs of electrode sheets 10 may have different numbers of dielectric elements 13.

The present application further provides an electrode sheet 10. Fig. 2 is a schematic block diagram of an electrical connection of one of the electrode pads shown in fig. 1 to an adapter. It is worth noting that: the arrangement of the dielectric elements 13 shown in fig. 2 is for more clearly showing the electrical connection between the electrode pads and the adaptor, and the arrangement of the dielectric elements 13 shown in fig. 2 does not represent the arrangement of the dielectric elements 13 in the spatial structure. Referring to fig. 1 and 2, the electrode sheet 10 includes a flexible printed circuit 11, a plurality of electrode units 12 electrically connected to the flexible printed circuit 11 at intervals, an adhesive member (not shown) applied to the plurality of electrode units 12, and a first cable 15 electrically connected to the flexible printed circuit 11. One path of AC signal line 17, multiple paths of grounding lines 18 and multiple paths of signal output lines 19 are embedded in the flexible circuit board 11. The first cable 15 has a plurality of core wires (not shown), each of which is electrically connected to one of the AC signal lines 17, the plurality of ground lines 18, and the plurality of signal output lines 19 of the flexible printed circuit 11 in a one-to-one correspondence.

Each electrode unit 12 includes a dielectric member 13 and a temperature detector 14 corresponding to the dielectric member 13. The dielectric element 13 and the temperature detector 14 are both soldered to the flexible wiring board 11. The dielectric element 13 is configured for applying an alternating electric field to a tumor site of a patient. The temperature detector 14 detects a temperature of a body surface of the patient to which the electrode sheet 10 is attached and outputs a detection signal to the adapter 20. Specifically, the temperature detector 14 detects the temperature of an adhesive member (not shown) of the electrode sheet 10 that is in contact with the body surface of the patient, and indirectly feeds back a temperature signal of the body surface of the patient to which the electrode sheet 10 is applied, through the temperature of the adhesive member (not shown). Each of the temperature detectors 14 has a ground terminal (not shown) and a signal terminal (not shown). The plurality of electrode units 12 are divided into a plurality of groups. Each set of electrode units 12 comprises at least one electrode unit 12.

The AC signal lines 17 of the flexible wiring board 11 are configured to transmit the alternating current signals generated by the electric field generator 30 to each of the dielectric elements 13. In this embodiment, the AC signal line 17 of the flexible printed circuit 11 is electrically connected to the first cable 15, and is further electrically connected to the electric field generator 30 through the adaptor 20, for receiving the AC signal generated by the electric field generator 30 and transmitting the AC signal to the dielectric element 13. The alternating current signal generated by the electric field generator 30 is transmitted to the AC signal line 17 of the first flexible wiring board 11 through the adaptor 20 and the first cable 15 in this order.

The multiple ground lines 18 have only one ground line 18 turned on at the same time, and the remaining three ground lines 18 are turned off. The multiple grounding lines 18 are respectively used for short-circuiting the temperature detectors 14 of the corresponding electrode units 12 in the multiple groups of electrode units 12 to ground. That is, the multiple ground lines 18 short-circuit the multiple temperature detectors 14 in each group to ground, respectively. The respective ground terminals (not shown) of the plurality of temperature detectors 14 located in the same group are all short-circuited via the same ground line 18 of the flexible printed circuit 11, and the respective ground terminals (not shown) of the plurality of temperature detectors 14 located in different groups and corresponding to each other are connected in parallel via the different ground lines 18 of the flexible printed circuit 11.

Each of the multiple signal output lines 19 is used to short the temperature detector 14 of at most one electrode unit 12 in each group of electrode units 12 to an external device for receiving a detection signal. The temperature detectors 14 connected to each of the multiple signal output lines 19 are different from each other so as to prevent the signal output lines 19 from outputting repeated signals subsequently. That is, when the number of the electrode units 12 in a group of the electrode units 12 is the same as the number of the signal output lines 19, each signal output line 19 is electrically connected to the respective temperature detectors 14 of the plurality of electrode units 12 in the group in a one-to-one correspondence manner; when the number of the electrode units 12 in a group of the electrode units 12 is less than the number of the signal output lines 19, at least one signal output line 19 is not electrically connected to the electrode units 12, and the remaining signal output lines 19 are respectively and electrically connected to the temperature detectors 14 of different electrode units 12 in the group of the electrode units 12. In this embodiment, the external device for receiving the detection signal is the adaptor 20. The signal ends (not shown) of the plurality of temperature detectors 14 located in the same group are respectively connected in parallel through different signal output lines 19 of the flexible printed circuit 11, and the signal ends (not shown) of the plurality of temperature detectors 14 located in different groups and corresponding to each other are all short-circuited through the same signal output line 19 of the flexible printed circuit 11.

The electrode sheet 10 of the present application is short-circuited by the same ground line 18 of the flexible circuit board 11 at respective ground terminals (not shown) of a plurality of temperature detectors 14 located in the same group, the respective ground terminals (not shown) of a plurality of temperature detectors 14 located in different groups and corresponding to each other are respectively connected in parallel by different ground lines 18 of the flexible circuit board 11, the respective signal terminals (not shown) of a plurality of temperature detectors 14 located in the same group are respectively connected in parallel by different signal output lines 19 of the flexible circuit board 11, the respective signal terminals (not shown) of a plurality of temperature detectors 14 located in different groups and corresponding to each other are short-circuited by the same signal output line 19 of the flexible circuit board 11, and the multiple ground lines 18 are only conducted by one ground line 18 at the same time, and the connection manner of the temperature detectors 14 with the ground lines 18 and the signal output lines 19 can realize that the one signal output line 19 obtains the detection signals of the temperature detectors 14 located in the same group at different times; the detection signals of the temperature detectors 14 of all the electrode units 10 of the electrode slice 10 which are positioned in different groups can be obtained in a time-sharing manner through the multi-path signal output line 19, so that the detection of the body surface temperature of the patient is more comprehensive and accurate.

The AC signal line 17, the ground line 18 and the signal output line 19 embedded in the flexible circuit board 11 are 10 lines in total, so that the first cable 15 can be configured with a cable with 10-core wires, the increase of the core of the first cable 15 is avoided, and the purpose of controlling the overall weight of the electrode plate 10 is achieved. The ground line 18 and the signal output line 19 embedded in the flexible wiring board 11 constitute 9 lines in total. In this embodiment, the ground line 18 embedded in the flexible printed circuit 11 is 4 lines, and the signal output line 19 is 5 lines.

In the present embodiment, the dielectric element 13 in each electrode unit 12 is connected in parallel to the AC signal line 17. In other embodiments, the dielectric elements 13 in each electrode unit 12 are connected in series to the AC signal line 17. In other another embodiment, the series portion of the dielectric element 13 in each electrode unit 12 is connected in parallel to the AC signal line 17.

The electrode units 12 are arranged at intervals on the flexible wiring board 11 substantially in the form of a two-dimensional array. Referring to fig. 2, the electrode sheet 10 in the present embodiment has 4 sets of electrode units 12, each set of electrode units 12 having 5 electrode units 12. The electrode sheet 10 in the present embodiment has 20 electrode units 12. The 20 electrode units 12 may be arranged in a two-dimensional array. The 20 electrode units 12 of the electrode sheet 10 may be arranged in six rows, where the first row and the fourth row are four electrode units 12, the four electrode units 12 in each of the first row and the fourth row are located in each of the second row to the fifth row, the two middle rows are six electrode units 12, and the six electrode units 12 in each of the two middle rows are located in each of the first row to the sixth row. Among the 20 electrode units 12 arranged in four rows and six columns, one set of the electrode units 12 is composed of 5 electrode units 12 close to each other, and the 20 electrode units 12 are grouped into four sets of the electrode units 12, so as to facilitate the wiring design of the AC signal lines 17, the ground lines 18, and the signal output lines 19 in the flexible wiring board 11. The 20 electrode units 12 of the electrode sheet 10 may also be arranged in four rows and five columns. Each row of the electrode sheet 10 comprises 5 electrode units 12, each 5 electrode units 12 constituting a group. In other embodiments, the 20 electrode units 12 may be arranged in other manners. Of course, in other embodiments of the present application, the electrode sheet 10 may have other numbers of electrode units 12. In summary, the implementation of the present application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

Each electrode unit 12 includes a dielectric element 13 and a temperature detector 14. In the embodiment shown in fig. 2, the dielectric element 13 may be a dielectric element, such as a dielectric ceramic sheet. The temperature detector 14 may be a thermistor element, but of course, in other embodiments of the present application, the temperature detector 14 may be a temperature sensor other than a thermistor. Each dielectric element 13 has a through hole (not shown) formed therethrough at a central portion thereof, and the through hole of each dielectric element 13 accommodates a corresponding temperature detector 14 therein. Each electrode unit 12 may also include a diode 16. The diode 16 is connected in series with the temperature detector 14 of the same electrode unit 12, and can prevent reverse inflow of current to prevent detection signals from other electrode units 12 from affecting the temperature detector 14.

The electrode sheet 10 shown in fig. 2 includes 4-way ground wires 18, each of the 4-way ground wires 18 being used to ground the electrode units 12 located in the same group. The 4-way ground wires 18 of the electrode sheet 10 are a first ground wire 18-1, a second ground wire 18-2, a third ground wire 18-3 and a fourth ground wire 18-4, respectively. In the four groups of electrode units 12 of the electrode sheet 10, the first group of electrode units 12 are electrode units 12-1 to 12-5, the second group of electrode units 12 are electrode units 12-6 to 12-10, the third group of electrode units 12 are electrode units 12-11 to 12-15, and the fourth group of electrode units 12 are electrode units 12-16 to 12-20. Specifically, the first ground line 18-1 is used to ground the first group of electrode units 12 (i.e., the electrode units 12-1 to 12-5); the second ground line 18-2 is used to ground the second group of electrode units 12 (i.e., electrode units 12-6 to electrode units 12-10); the third ground line 18-3 is used to ground the third group of electrode units 12 (i.e., the electrode units 12-11 to 12-15); the fourth ground line 18-4 is used to ground the fourth set of electrode units 12 (i.e., electrode units 12-16 through electrode units 12-20). It should be noted that the ground lines 18 can be selectively closed or opened, which can be achieved by connecting each ground line 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode unit 12" may refer to grounding the temperature detector 14 in the electrode unit 12; the diode 16 may be connected in series with the temperature detector 14 of the same electrode unit 12 and grounded together. In short, each ground line 18 shorts and grounds the ground terminals of the temperature detectors 14 of all the electrode units 12 in each group of electrode units 12.

The electrode sheet 10 shown in fig. 2 further includes 5 signal output lines 19, one end of each signal output line 19 is respectively connected to at most one electrode unit 12 in each group of electrode units 12, and the other end thereof is used for being connected to an adaptor 20 for receiving a detection signal. That is, for each set of electrode units 12, each signal output line 19 can be selectively connected to one of the electrode units 12 or not connected to any one of the electrode units 12 in the set of electrode units 12, and the electrode units 12 to which each signal output line 19 is connected are different from each other, so as to avoid the signal output lines 19 from outputting repeated signals subsequently. Specifically, the signal ends of the temperature detectors 14 of the electrode units 12 in each group of electrode units 12 are respectively connected to different signal output lines 19 in a one-to-one correspondence.

In the present embodiment, the 5 signal output lines 19 of the electrode sheet 10 include a first signal output line 19-1, a second signal output line 19-2, a third signal output line 19-3, a fourth signal output line 19-4, and a fifth signal output line 19-5. One end of a first signal output line 19-1 is respectively connected to the signal ends of the temperature detectors 14 of the electrode unit 12-1, the electrode unit 12-6, the electrode unit 12-11 and the electrode unit 12-16; one end of the second signal output line 19-2 is connected to the signal ends of the temperature detectors 14 of the electrode unit 12-2, the electrode unit 12-7, the electrode unit 12-12 and the electrode unit 12-1, respectively; one end of a third signal output line 19-3 is respectively connected to the signal ends of the temperature detectors 14 of the electrode units 12-3, 12-8, 12-13 and 12-18; one end of a fourth signal output line 19-4 is connected to the signal ends of the electrode units 12-4, 12-9, 12-14, and the temperature detectors 14 of the electrode units 12-19, respectively; one end of a fifth signal output line 19-5 is connected to the signal ends of the respective temperature detectors 14 of the electrode units 12-5, 12-10, 12-15, 12-20, respectively.

Specifically, each signal end of each temperature detector 14 of the electrode units 12-1 to 12-5 in the first group of electrode units 12 is electrically connected to a corresponding one of the 5 signal output lines 19 (the first signal output line 19-1 to the fifth signal output line 19-) -one by one. The signal ends of the electrode units 12-6 to the temperature detectors 14 of the electrode units 12-10 in the second group of electrode units 12 are also electrically connected to corresponding ones of the 5 signal output lines 19 (the first signal output line 19-1 to the fifth signal output line 19-) one by one. The signal ends of the electrode units 12-11 to the temperature detectors 14 of the electrode units 12-15 in the third group of electrode units 12 are also electrically connected to one signal output line 19 corresponding to each of the 5 signal output lines 19 (the first signal output line 19-1 to the fifth signal output line 19-). The signal ends of the temperature detectors 14 of the electrode units 12-16 to 12-20 in the fourth group of electrode units 12 are also electrically connected to corresponding ones of the 5 signal output lines 19 (the first signal output line 19-1 to the fifth signal output line 19-) -one by one.

In the first group of electrode units 12, the signal end of the temperature detector 14 of the electrode unit 12-1 is connected with a first signal output line 19-1; the signal end of the temperature detector 14 of the electrode unit 12-2 is connected to a second signal output line 19-2; the signal end of the temperature detector 14 of the electrode unit 12-3 is connected to a third signal output line 19-3; the signal end of the temperature detector 14 of the electrode unit 12-4 is connected to a fourth signal output line 19-4; the signal terminal of the temperature detector 14 of the electrode unit 12-5 is connected to a fifth signal output line 19-5. In the second group of electrode units 12, the signal end of the temperature detector 14 of the electrode unit 12-6 is connected with a first signal output line 19-1; the signal end of the temperature detector 14 of the electrode unit 12-7 is connected to a second signal output line 19-2; the signal end of the temperature detector 14 of the electrode unit 12-8 is connected to a third signal output line 19-3; the signal end of the temperature detector 14 of the electrode unit 12-9 is connected to a fourth signal output line 19-4; the signal terminal of the temperature detector 14 of the electrode unit 12-10 is connected to a fifth signal output line 19-5. In the third group of electrode units 12, the signal end of the temperature detector 14 of the electrode units 12-11 is connected with a first signal output line 19-1; the signal end of the temperature detector 14 of the electrode unit 12-12 is connected to a second signal output line 19-2; the signal end of the temperature detector 14 of the electrode unit 12-13 is connected to a third signal output line 19-3; the signal end of the temperature detector 14 of the electrode unit 12-14 is connected to a fourth signal output line 19-4; the signal terminal of the temperature detector 14 of the electrode unit 12-15 is connected to a fifth signal output line 19-5. In the fourth group of electrode units 12, the signal end of the temperature detector 14 of the electrode units 12-16 is connected with a first signal output line 19-1; the signal end of the temperature detector 14 of the electrode unit 12-17 is connected to a second signal output line 19-2; the signal end of the temperature detector 14 of the electrode unit 12-18 is connected to a third signal output line 19-3; the signal end of the temperature detector 14 of the electrode unit 12-19 is connected to a fourth signal output line 19-4; the signal terminal of the temperature detector 14 of the electrode unit 12-20 is connected to a fifth signal output line 19-5.

In short, each signal output line 19 shorts signal terminals of the temperature detectors 14 of different groups and corresponding electrode units 12 together and is used for connection to an external device. The signal ends of the respective temperature detectors 14 of the respective electrode units 12 of the same group are connected to different signal output lines 19, respectively, and are connected to an external device through the different signal output lines 19. That is, the signal ends of the temperature detectors 14 of the electrode units 12 in each group of electrode units 12 are respectively connected to a corresponding signal output line 19 and are connected to an external device through the corresponding signal output line 19. The grounding ends of the temperature detectors 14 of the electrode units 12 of the same group are all in short circuit grounding through the same grounding line 18. The signal ends of the temperature detectors 14 of the different groups of and corresponding electrode units 12 are all connected to an external device through the same signal output line 19. That is, the signal ends of the temperature detectors 14 of different groups and corresponding to the electrode units 12 are all connected in parallel to the same signal output line 19 and connected to an external device through the signal output line 19. The grounding ends of the temperature detectors 14 of the different groups of corresponding electrode units 12 are respectively grounded in a short circuit with the corresponding one-way grounding line 18. That is, the grounding terminals of the temperature detectors 14 of the electrode units 12 in different groups and corresponding to each other are respectively short-circuited to ground through the different multi-path grounding lines 18. The signal terminals of the temperature detectors 14 of the different sets of the electrode units 12 that are not aligned are connected to an external device via different signal output lines 19, and the ground terminals of the temperature detectors 14 of the different sets of the electrode units 12 that are not aligned are also short-circuited to ground via different ground lines 18. That is, the signal terminals of the temperature detectors 14 of the different sets of the electrode units 12 that are not corresponding are connected to an external device via different signal output lines 19, respectively, and the ground terminals of the temperature detectors 14 of the different sets of the electrode units 12 that are not corresponding are short-circuited to ground via different ground lines 18, respectively.

The AC signal line 17, the multiple ground lines 18, and the multiple signal output lines 19 are all lines embedded in the flexible wiring board 11. The flexible wiring board 11 is electrically connected to the first cable 15. The AC signal line 17, the multi-path ground line 18 and the multi-path signal output line 19 embedded in the flexible circuit board 11 are electrically connected to a corresponding one of the cores in the first cable 15.

During the application of the electrode sheet 10, the detection signals of each temperature detector 14 in 20 electrode units 12 can be obtained in a time-sharing manner by using only 5 signal output lines 19. Specifically, each ground wire 18 of the multiple ground wires 18 of the electrode sheet 10 may be individually turned on in turn, and the detection signal of the temperature detector 14 of each electrode unit 12 of the group of electrode units 12 grounded by the ground wire 18 may be acquired in the on state of each ground wire 18. So that the detection signals of the temperature detectors 14 of all the electrode units 12 of the electrode sheet 10 can be obtained after the operation of sequentially turning on the corresponding one of the ground lines 18 a plurality of times. In the prior art, since each temperature detector 14 outputs a detection signal at the same time, 20 independent signal output lines 19 are required to detect the temperature of all the dielectric elements 13, which increases the wiring difficulty, the processing difficulty and the cost of the flexible printed circuit board 11; and the corresponding first cable 15 would also be required to include 22 cores (including the additional 1-way ground wire 18 and 1-way AC signal wire 17), which would substantially increase the weight of the entire electrode sheet 10 and increase the manufacturing cost of the first cable 15. As can be seen from the embodiment of fig. 2, the first cable 15 of the electrode plate 10 of the present application only includes 10 cable cores (not shown), that is, 4 cable cores (not shown) electrically connected to the grounding line 18, 5 cable cores (not shown) electrically connected to the signal output line 19, and 1 cable core (not shown) electrically connected to the AC signal line 17, so as to effectively control the overall weight of the electrode plate 10, avoid the electrode plate 10 from affecting the adhesion effect between the electrode plate 10 and the body surface corresponding to the tumor site of the patient due to the increase of the number of the cable cores (not shown) of the first cable 15, and reduce the processing cost; in addition, only 1 AC signal line 17, 5 signal output lines 19 and 4 ground lines 18 are arranged on the flexible circuit board 11, so that signals detected by the temperature detectors 14 of the 20 electrode units 12 can be obtained, the temperatures of all the electrode units 12 of the electrode sheet 10 can be comprehensively monitored, and then the alternating current signals applied to the electrode sheet 10 are controlled by the temperature signals of the electrode units 12, so that low-temperature scald on the skin surface of a patient to which the electrode units 12 are attached due to overhigh temperature of the electrode units 12 is avoided, the wiring design of the flexible circuit board 11 is simplified, and the manufacturing cost is reduced.

In the present embodiment, each electrode sheet 10 may further include a first connector 40. The first connectors 40 are each configured to connect a corresponding one of the electrode pads 10 to the adaptor 20. In the present embodiment, as shown in fig. 1, the first connector 40 is a plug, and is disposed at one end of the first cable 15 of the corresponding electrode pad 10 away from the flexible wiring board 11. The adaptor 20 is provided with a socket 27 corresponding to each of the plurality of first connectors 40. The first connector 40 has 10 interfaces (1-10) corresponding to the cores (not shown) of the first cable 15, respectively, and the first connector 40 is plugged into the corresponding socket 27 of the adaptor 20 to electrically connect the 4 ground lines 18, the 5 signal output lines 19 and the AC signal line 17 on the flexible circuit board 11 to the adaptor 20. The first connector 40 is provided in the form of a plug to facilitate quick mounting and dismounting of the electrode tabs 10 and the adapter 20, and in the event of a failure of one of the electrode tabs 10, the failed electrode tab 10 can be replaced with another electrode tab 10.

The number of the ground wires 18 embedded in the flexible printed circuit 11 of the present application is related to the number of groups into which the plurality of electrode units 12 arranged on the flexible printed circuit 11 are divided, that is, the number of the ground wires 18 is the same as the number of groups of the electrode units 12 of the electrode sheet 10. The number of signal output lines 19 embedded in the flexible wiring board 11 is related to the number of electrode units 12 in each group of the electrode sheets 10. Specifically, the number of the signal output lines 19 embedded in the flexible wiring board 11 is related to one of the electrode units 12 having the largest number of the electrode units 12 among the electrode units 12. Specifically, the number of signal output lines 19 embedded in the flexible wiring board 11 is the same as the total number of electrode units 12 in one group having the largest number of electrode units 12. The total number of the ground lines 18 and the signal output lines 19 is less than the number of the temperature detectors.

The present application further provides an electric field therapy system. The electric field treatment system 1 of the present application will be described in detail with reference to fig. 1 to 4. The electric field treatment system 1 of the present application includes at least one pair of electrode pads 10 as described above, an adapter 20 electrically connected to the electrode pads 10, and an electric field generator 30 electrically connected to the adapter 20. The adaptor 20 is connected between the electrode sheet 10 and the electric field generator 30. The electric field generator 30 provides an alternating current signal to each dielectric element 13 in the sets of electrode units 12 of the electrode sheet 10 via the adaptor 20, the AC signal line 17 of the electrode sheet 10. The adaptor 20 transmits the alternating current signal generated by the electric field generator 30 to the AC signal line 17 of the electrode pad 10, and is also configured to receive the detection signal output from the multiplexed signal output line 19 of the electrode pad 10.

Referring to fig. 1 and 2, the adaptor 20 includes: a plurality of sets of switches 24, a controller 21, a plurality of sets of analog-to-digital converters 22, and a communication transceiver 26. The adapter 20 includes multiple circuit lines (not numbered) therein. The multiple circuit lines (not numbered) are electrically connected with the multiple grounding lines 18, the multiple signal output lines 19 and the multiple AC signal lines 17 in the corresponding flexible circuit board 11 one by one through the first cable 15 of the corresponding electrode plate 10.

Each set of switches 24 has a plurality of switches 24, and the plurality of switches 24 are respectively connected into the adaptor 20 and are respectively electrically connected to circuit lines (not numbered) corresponding to the multiple grounding lines 18 of a corresponding one of the electrode plates 10, and are configured to control the multiple grounding lines 18 to be turned on or off. A plurality of circuit lines (not numbered) electrically connected to the plurality of ground lines 18 of the electrode sheet 10, respectively, are grounded at one end near the switch 24. As shown in FIG. 2, the plurality of switches 24 are a first switch 24-1, a second switch 24-2, a third switch 24-3, and a fourth switch 24-4, respectively. The switches 24 in the same group control the on and off of the multiple grounding wires 18 of the flexible circuit board 11 of the same electrode plate 10. Specifically, the switches in the same group respectively control the closing or opening of the first ground line 18 electrically connected thereto in the same electrode sheet 10. In the present embodiment, the first switch 24-1 is used to control the on/off of the first ground line 18-1 of the corresponding electrode sheet 10, and thus control the on/off of each temperature detector 14 of the first group of electrode units 12 (i.e. the electrode units 12-1 to 12-5) of the electrode sheet 10; the second switch 24-2 is used for controlling the second grounding wire 18-2 of the electrode plate 10 to be closed or opened, and further controlling the energization and the deenergization of each temperature detector 14 of the second group of electrode units 12 (i.e. the electrode units 12-6 to the electrode units 12-10) of the electrode plate 10; the third switch 24-3 is used for controlling the connection or disconnection of the third ground line 18-3 of the electrode plate 10, and further controlling the energization and the deenergization of each temperature detector 14 of the third group of electrode units 12 (i.e. the electrode units 12-11 to the electrode units 12-15) of the electrode plate 10; the fourth switch 24-4 is used for controlling the fourth ground line 18-4 of the electrode plate 10 to be closed or opened, and further controlling the energization and deenergization of each temperature detector 14 of the fourth group of electrode units 12 (i.e. the electrode units 12-16 to the electrode units 12-10) of the electrode plate 10. The plurality of switches 24 may be mechanical switches, such as relays. The plurality of switches 24 may also be electronic switches, and each switch 24 may be opened and closed by an additional controller.

In this embodiment, the switches 24 are all electronic switches. The controller 21 is connected to the plurality of sets of switches 24, and is configured to sequentially and cyclically control the on/off states of the plurality of switches 24 in each set of switches 24, and sequentially and individually turn on each ground line 18 in the plurality of ground lines 18 of the corresponding electrode patch 10, so as to continuously monitor the temperature signals detected by all the temperature detectors 14 on the electrode patch 10, and further indirectly obtain the temperature of the body surface of the patient to which the electrode units 12 of the electrode patch 10 are attached.

Each group of the analog-to-digital converters 22 is electrically connected to the multi-path signal output lines 19 of the electrode pads 10 through a multi-path circuit line (not numbered) in the adaptor 20 and the first cable 15 of the corresponding electrode pad 10, and is configured to receive the detection signal transmitted by the multi-path signal output line 19 of the corresponding electrode pad 10 and convert the detection signal from an analog signal to a digital signal. Each group of analog-to-digital converters 22 includes a plurality of detection channels a, B, C, D, E, each detection channel is used for connecting a corresponding one of the multiple signal output lines 19 to the corresponding one of the multiple signal output lines 19. As shown in fig. 2, each group of the analog-to-digital converters 22 includes 5 detection channels, which are a first detection channel a, a second detection channel B, a third detection channel C, a fourth detection channel D, and a fifth detection channel E. The first detection channel A is connected with a first signal output line 19-1, the second detection channel B is connected with a second signal output line 19-2, the third detection channel C is connected with a third signal output line 19-3, the fourth detection channel D is connected with a fourth signal output line 19-4, and the fifth detection channel E is connected with a fifth signal output line 19-5. Each detection channel is for receiving a detection signal of the temperature detector 14 of the electrode unit 12 to which the corresponding signal output line 19 is connected. In addition, each of the line detection channels is connected to a supply voltage source (VCC) via a set of high precision resistors 23 within the commutator 20 for providing a detection voltage to the line detection channel. The supply voltage source (VCC) is direct current.

Communications transceiver 26 is configured to acquire sets of digital signals output by analog-to-digital converter 22 and transmit the digital signals to electric field generator 30. The electric field generator 30 is further configured to adjust the voltage of the alternating electrical signals applied to the dielectric elements 13 in the sets of electrode units 12 of the electrode sheet 10 in accordance with the received digital signals. Illustratively, when any one of the received digital signals exceeds a preset threshold, it indicates that the temperature of at least one dielectric element 13 in the electrode patch 10 exceeds a preset threshold temperature (e.g., 41 ℃, 42 ℃, etc.), and at this time, the voltage of the ac signal output by the electric field generator 30 may be appropriately reduced to avoid low-temperature scald on the skin of the patient caused by the electrode patch 10. The preset threshold temperature and the preset threshold can be determined according to relevant experimental data, and the range can be 37-42 ℃. The communication transceiver 26 is controlled by the controller 21 and serially transmits the digital signals converted by the plurality of sets of analog-to-digital converters 22.

The operation of the electric field treatment system 1 of the present application will now be described in detail with reference to figures 2 and 3.

Each detection channel of each group of analog-to-digital converters 22 collects only a detection signal, which may be a voltage value, of a corresponding one of the temperature detectors 14 in the same group of electrode units 12 at the same time. Only 1 switch 24 of the 4 switches 24 is on at the same time, and the other 3 are off. So configured, each set of analog-to-digital converters 22 can only collect the voltage values of all the temperature detectors 14 of one set of electrode units 12 short-circuited with one of the grounding lines 18 corresponding to the conducting switches 24. Specifically, when the switch 24-1 is closed, the other three switches 24-2, 24-3, 24-4 are all open, the temperature detectors 14 of the electrode units 12-1 to 12-5 are all powered on, the temperature detectors 14 of the electrode units 12-6 to 12-20 are powered off, the first detection channel a of the analog-to-digital converter 22 is short-circuited with the temperature detectors 14 of the electrode units 12-1, 12-6, 12-11, 12-16, and since the ground terminals of the temperature detectors 14 of the electrode units 12-6, 12-11, 12-16 are all open, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature detector 14 thereof, the resistance of the temperature detector 14 of the electrode unit 12-1 is not affected, so that only the temperature detector 14 of the electrode unit 12-1 on the first detection channel a of the analog-to-digital converter 22 is effectively operated, and the collected detection signal (voltage value) is the voltage value of the temperature detector 14 of the electrode unit 12-1. Similarly, the voltage value collected on the second detection channel B in the analog-to-digital converter 22 is the voltage value of the temperature detector 14 of the electrode unit 12-2. The voltage value collected on the third detection channel C in the analog-to-digital converter 22 is the voltage value of the temperature detector 14 of the electrode unit 12-3. The voltage value collected on the fourth detection channel D in the analog-to-digital converter 22 is the voltage value of the temperature detector 14 of the electrode unit 12-4. The voltage value collected on the fifth detection channel E in the analog-to-digital converter 22 is the voltage value of the temperature detector 14 of the electrode unit 12-5.

The controller 21 and the plurality of sets of analog-to-digital converters 22 may automatically perform operations by pre-programmed program codes, for example, the controller 21 first closes the switch 24-1 of the plurality of sets of switches 24, and opens the remaining switches 24-2 to the switch 24-4, during which the plurality of sets of analog-to-digital converters 22 acquire and store the detection values of the respective detection channels in a separately provided memory, and then after a preset time interval, the controller 21 further closes the switch 24-2 of the plurality of sets of switches 24, opens the switch 24-1, the switch 24-3, and the switch 24-4, during which the plurality of sets of analog-to-digital converters 22 acquire the detection values of the respective detection channels. By turning on each switch 24 of the plurality of sets of switches 24 individually in turn, the detected values of all the temperature detectors 14 on the electrode sheet 10 can be obtained, and further, the detected values of all the temperature detectors 14 on at least one pair of electrode sheets 10 can be obtained through such operation.

In this embodiment, the adapter 20 of the electric field treatment system 1 may further include a second connector 50. The second connector 50 is configured to connect the adaptor 20 to the electric field generator 30. Fig. 4 is a schematic block diagram of the adapter 20 and the second connector 50 in the electric field treatment system 1 of the present invention. As shown in fig. 4, the second connector 50 may include 8 input ports (1-8), wherein the 1 st to 4 th input ports are respectively used for connecting to the corresponding first connectors 40 and for further transmitting the AC signal generated by the electric field generator 30 to the AC signal lines 17 of the corresponding electrode sheets 10 through the corresponding first connectors 40, so that the dielectric element 13 of each electrode unit 12 on the electrode sheets 10 is connected with the AC signal and applied to the tumor site of the patient and forms an alternating electric field with the opposite electrode sheet 10 for treating the tumor. The 5 th input port is used to ground the commutator 20, and the 6 th input port is connected to the controller 21 and is used to supply a supply Voltage (VCC) to the controller 21. The 7 th and 8 th input ports are connected to the transmitter and receiver of the communications transceiver 26 via lines TX and RX, respectively.

The adaptor 20 of the electric field treatment system 1 may further include: a second cable 25. The second cable 25 is configured to connect the adaptor 20 and the second connector 50. The second cable 25 may include a plurality of conductive wires, each corresponding to one of the plurality of input ports of the second connector 50. The second connector 50 may be made in the form of a plug, similar to the first connector 40, to facilitate connection or disconnection with the electric field generator 30.

Fig. 3 shows a schematic block diagram of an electrode patch 10 and an adapter 20 in an electric field treatment system 1 according to another embodiment of the present application. Unlike the electric field treatment system 1 shown in fig. 2, the electrode patch 10 of this embodiment includes only 13 electrode units 12, and as shown in fig. 3, the 13 electrode units 12 are divided into 3 groups, wherein the first two groups each include 5 electrode units 12, and the third group includes only 3 electrode units 12. Therefore, only the 3-way ground 18 among the four-way ground 18 of the electrode sheet 10 shown in fig. 3 is able to be efficiently energized. Meanwhile, the electrode plate 10 comprises 5 signal output lines 19, wherein each signal output line 19 is respectively connected with the temperature detector 14 of at most one electrode unit 12 in each group of electrode units 12. Specifically, the first signal output line 19-1, the second signal output line 19-2, and the third signal output line 19-3 are each connected to the temperature detector 14 of a corresponding one of the electrode units 12 in each of the 3 groups of electrode units 12, respectively, while the fourth signal output line 19-4 and the fifth signal output line 19-5 are connected to only the temperature detector 14 of a corresponding one of the electrode units 12 in each of the first two groups of electrode units 12, and neither the fourth signal output line 19-4 nor the fifth signal output line 19-5 is connected to the electrode unit 12 in the third group. That is, the first signal output line 19-1, the second signal output line 19-2, and the third signal output line 19-3 are each connected in parallel with the signal terminals of the respective temperature detectors 14 of the 3 electrode units 12, and the fourth signal output line 19-4 and the fifth signal output line 19-5 are connected in parallel with the signal terminals of only the respective temperature detectors 14 of the 2 electrode units 12. The control method of the electric field treatment system 1 shown in fig. 3 is similar to the control method of the electric field treatment system 1 shown in fig. 2, and is not repeated herein, except that the electric field treatment system 1 shown in fig. 3 only needs to sequentially close the 3 switches 24 (the first switch 24-1, the second switch 24-2, and the third switch 24-3), and during the closing period of the third switch 24-3, the analog-to-digital converter 22 only has the first three detection channels (a, B, and C) capable of acquiring the detection signals.

The present application also provides a method of controlling an electric field therapy system 1, the method comprising: and sequentially and individually turning on each of the multiple ground wires 18 of the electrode sheet 10, wherein in a state where each ground wire 18 is turned on: acquiring a detection signal of the temperature detector 14 of each electrode unit 12 in the group of electrode units 12 that has been grounded by the grounding line 18, which is received by the adaptor 20; the alternating current signal applied to each electrode unit 12 is adjusted according to the obtained detection signal.

FIG. 5 is a flow chart of a method 500 of controlling the electric field therapy system 1 in accordance with one embodiment of the present invention. The control method 500 is used to control the electric field treatment system 1 shown in figure 2. As shown in fig. 5, the method 500 includes:

in step 501, the controller 21 of the adapter 20 simultaneously controls 4 switches 24 of one set of switches 24 of the multiple sets of switches 24, so that one switch 24 of the 4 switches 24 (the first switch 24-1, the second switch 24-2, the third switch 24-3, and the fourth switch 24-4) is turned on, and the remaining 3 switches 24 are turned off.

In step 502, the detection signals of the plurality of temperature detectors 14 short-circuited with the turned-on switch 24 are collected by one of the plurality of analog-to-digital converters 22 in the plurality of groups of analog-to-digital converters 22 of the adapter 20 through the corresponding detection channels, and the detection signals are voltage analog signals.

In step 503, one of the analog-to-digital converters 22 in the plurality of sets of analog-to-digital converters 22 of the adaptor 20 converts the collected voltage analog signal into a temperature digital signal.

The communication transceiver 26 of the adaptor 20 serially transmits the temperature digital signal to the electric field generator 30, step 504.

Steps 501-504 are repeated so that the voltage analog signal detected by each temperature detector 14 of the electrode sheet 10 is collected and converted into a temperature digital signal by the adaptor 20 and transmitted to the electric field generator 30. Specifically, when only the first switch 24-1 is closed, all the detection channels a-E of the analog-to-digital converter 22 will respectively collect the detection signals of the temperature detectors 14 of the electrode units 12-1 to 12-5; when only the second switch 24-2 is closed, all detection channels a-E of the analog-to-digital converter 22 will respectively collect detection signals from the electrode units 12-6 to the temperature detectors 14 of the electrode units 12-10; when only the third switch 24-3 is closed, all the detection channels a-E of the analog-to-digital converter 22 will collect the detection signals of the electrode units 12-11 to the temperature detector 14 of the electrode units 12-15, respectively; when only the fourth switch 24-4 is closed, all detection channels a-E of the analog-to-digital converter 22 will collect detection signals to the electrode units 12-16 to the temperature detector 14 of the electrode units 12-20, respectively. The specific operation principle is detailed in the related description of fig. 2, and is not described in detail here. In this way, the electric field generator 30 can obtain the temperature analog signals detected by all the temperature detectors 14 on the electrode sheet 10.

After the electric field generator 30 obtains the temperature digital signals of all the temperature detectors 14 of the corresponding electrode slices 10, the method further comprises the following steps: the electric field generator 30 compares a preset temperature threshold value set therein with all the acquired temperature digital signals and adjusts the ac signals applied to the respective electrode units of the corresponding electrode sheet 10 according to the comparison result.

The preset temperature threshold is 37-42 ℃. The adjusting of the ac signals applied to the electrode units of the corresponding electrode sheet 10 according to the comparison result specifically includes: when all the temperature digital signals are lower than the preset temperature threshold, maintaining or increasing the voltage of the alternating current signal applied to each electrode unit 12 of the corresponding electrode sheet 10; when a certain temperature digital signal is equal to or higher than a preset temperature threshold value, the ac voltage applied to each electrode unit 12 of the corresponding electrode sheet 10 is reduced to 0.

Each electrode unit 12 of the multiple groups of electrode units 12 of the electrode slice 10 comprises a temperature detector 14, the temperature detectors 14 of the corresponding multiple groups of electrode units 12 are sequentially grounded through each grounding wire 18, at most one electrode unit 12 in each group of electrode units 12 is electrically connected through each signal output line 19, detection signals of the temperature detectors 14 of the electrode units 12 in different groups of electrode slices can be acquired through each signal output line 19 in a time-sharing mode, and accordingly the body surface temperature of a patient can be detected more comprehensively and accurately.

The present application is only a preferred embodiment of the present application and should not be limited to the above embodiments, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims

1. An electrode sheet, comprising:

a plurality of dielectric elements configured to apply an alternating electric field to a tumor site of a patient;

a plurality of temperature detectors, each of which is disposed in one-to-one correspondence with the plurality of dielectric elements and configured to monitor a temperature of a body surface corresponding to a tumor site of a patient in real time and output a detection signal, each of the temperature detectors having a ground terminal and a signal terminal; and

the flexible circuit board is provided with a plurality of dielectric elements and a plurality of temperature sensors at intervals, and a path of AC signal line, a path of grounding line and a plurality of signal output lines are embedded in the flexible circuit board, wherein the path of AC signal line is configured to be electrically connected with all the dielectric elements arranged on the flexible circuit board and transmit AC signals to all the dielectric elements, the grounding lines are used for short-circuiting grounding ends of all the temperature detectors together, and the signal output lines are used for connecting signal ends of all the temperature detectors in parallel and transmitting detection signals of the temperature detectors together;

each temperature detector and one corresponding dielectric element form an electrode unit, the temperature sensors and the dielectric elements form a plurality of electrode units, the electrode units are divided into different groups, each group at least comprises one electrode unit, and the total number of the grounding wires and the signal output wires is less than the number of the temperature detectors.

2. The electrode sheet according to claim 1, characterized in that the number of the ground lines is related to the number of groups into which the plurality of electrode units are grouped, and the number of the signal output lines is related to the number of electrode units located in each of the different groups.

3. The electrode pad according to claim 2, wherein the number of ground lines is equal to the number of groups into which the plurality of electrode units are grouped, and the number of signal output lines is related to the number of electrode units of a group having the largest number of electrode units.

4. The electrode sheet according to claim 3, characterized in that the number of signal output lines is equal to the total number of electrode units in a group of electrode units having the most electrode units.

5. The electrode sheet according to claim 1, wherein the grounding ends of the temperature detectors of the electrode units in the same group are all in short circuit grounding with the same grounding line, and the signal ends of the temperature detectors of the electrode units in the same group are respectively connected with signal output lines which correspond to the signal ends and are different from each other.

6. The electrode sheet of claim 5, wherein the grounding ends of the temperature detectors of the different groups of corresponding electrode units are respectively short-circuited with the corresponding grounding wires which are different from each other, and the signal ends of the temperature detectors of the different groups of corresponding electrode units are all connected to the same signal output line in parallel.

7. The electrode sheet according to claim 6, wherein the grounding ends of the temperature detectors of different groups of the corresponding electrode units are respectively short-circuited with one grounding line corresponding to the electrode units and different from the grounding lines, and the signal ends of the temperature detectors of different groups of the corresponding electrode units are respectively connected with one signal output line corresponding to the electrode units and different from the signal output line.

8. The electrode sheet of any one of claims 1 to 7, wherein only one of the multiple grounding wires is on and the rest of the multiple grounding wires are off at the same time.

9. The electrode sheet according to claim 8, wherein the detection signal of each temperature detector of each electrode unit in the same group is collected and transmitted when one of the grounding wires electrically connected to the grounding end of each temperature detector of the electrode unit in the group is conducted.

10. The electrode sheet according to claim 8, wherein detection signals of the temperature detectors of the electrode units of different groups are collected and transmitted in a time-sharing manner when multiple grounding wires are sequentially conducted.

11. The electrode sheet of claim 8, further comprising a first cable electrically connected to the flexible circuit board, wherein the first cable has a multi-core wire electrically connected to one of the AC signal lines, multiple ground lines, and multiple signal output lines embedded inside the flexible circuit board in a one-to-one correspondence manner.

12. The electrode sheet of claim 1, wherein each of said dielectric elements has a bore therethrough for receiving a corresponding one of the temperature sensors.

13. The electrode sheet of claim 1, wherein each of said electrode units further comprises a diode connected in series with said temperature detector.

14. An electric field therapy system, comprising:

at least one pair of electrode sheets according to any one of claims 1-13;

an electric field generator configured to apply alternating current signals to the plurality of dielectric elements of the electrode sheet via the AC signal lines of the electrode sheet; and

the adaptor is connected between the electrode plate and the electric field generator, is configured to transmit the alternating current signal generated by the electric field generator to the AC signal line of the electrode plate, and is also configured to receive the detection signals output by the multi-way signal output line of the electrode plate.

15. The electric field treatment system according to claim 14, wherein the adapter comprises a plurality of sets of switches, each set of switches comprising a plurality of switches, each switch electrically connecting one to a plurality of the ground lines of a corresponding electrode pad, the plurality of switches configured to control the plurality of ground lines of the corresponding electrode pad to be turned on or off.

16. The electric field treatment system according to claim 15, wherein the adapter further comprises a controller connected to the plurality of sets of switches, the controller controlling the on and off states of each of the plurality of sets of switches cyclically in turn to individually turn on each of the plurality of ground lines of the corresponding electrode sheet in turn.

17. The electric field treatment system according to claim 14, wherein the adapter further comprises a plurality of sets of analog-to-digital converters electrically connected to the multiple signal output lines of the plurality of electrode pads, respectively, each set of the analog-to-digital converters being configured to receive the detection signal transmitted by the multiple signal output line of the corresponding electrode pad and convert the detection signal from an analog signal to a digital signal.

18. The electric field treatment system of claim 17, wherein the adapter further comprises a communication transceiver configured to acquire the digital signals output by each set of the analog-to-digital converters and to transmit the digital signals to the electric field generator.

19. The electric field treatment system of claim 18, wherein the electric field generator is further configured to adjust an alternating current signal applied to dielectric elements of electrode units of the respective electrode patch as a function of the received digital signal.

20. The electric field treatment system according to claim 18, wherein the communication transceiver is controlled by the controller and serially transmits the digital signal converted by the analog-to-digital converter.

21. The electric field treatment system according to claim 17, further comprising a plurality of first connectors, each of the first connectors configured to connect a corresponding one of the electrode pads to the adapter, each of the first connectors being disposed at an end of the first cable of the corresponding electrode pad remote from the flexible circuit board.

22. The electric field treatment system according to claim 17, wherein each of said analog-to-digital converters includes a plurality of sensing channels, each sensing channel being coupled to a corresponding one of said plurality of signal output lines.

23. The electric field treatment system of claim 14, further comprising a second connector connecting the adapter to the electric field generator.

24. The electric field treatment system according to claim 23, further comprising a second cable for connecting the adapter and the second connector.

25. A method of controlling an electric field treatment system according to any one of claims 14 to 24, the method comprising:

and sequentially and independently conducting each ground wire in the multiple ground wires of the electrode plate, and acquiring a detection signal of the temperature detector of each electrode unit in a group of electrode units which are grounded by the ground wires and received by the adapter when each ground wire is in a conducting state.

26. The control method according to claim 25, wherein the adaptor includes a plurality of sets of switches, each set of switches including a plurality of switches, each switch electrically connecting a plurality of the ground lines of the corresponding electrode pad one by one and configured to control on or off of the plurality of ground lines, the individually turning on each ground line of the plurality of ground lines of the electrode pad in turn being performed by individually closing each switch of the plurality of switches in turn.

27. The control method of claim 26, wherein the adapter further comprises a plurality of sets of analog-to-digital converters, each set of analog-to-digital converters being connected to the multiple signal output lines of a corresponding electrode pad and configured to receive the detection signals transmitted by the multiple signal output lines of the corresponding electrode pad and convert the detection signals from analog signals to digital signals.

28. The control method according to claim 27, characterized by further comprising the step of: the digital signal is serially transmitted to the electric field generator.

29. The control method according to claim 28, characterized by further comprising the step of: and comparing the set preset temperature threshold value with all the digital signals and adjusting the alternating current signals applied to the dielectric elements of the electrode units of the corresponding electrode plates according to the comparison result.