CN113975262A - 含有福多司坦的药物组合物及其制备方法 - Google Patents
含有福多司坦的药物组合物及其制备方法 Download PDFInfo
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- CN113975262A CN113975262A CN202111045666.5A CN202111045666A CN113975262A CN 113975262 A CN113975262 A CN 113975262A CN 202111045666 A CN202111045666 A CN 202111045666A CN 113975262 A CN113975262 A CN 113975262A
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- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
分组 | 口感 |
实施例1 | 酸甜适宜,无异味 |
实施例2 | 酸甜适宜,无异味 |
实施例3 | 酸甜适宜,无异味 |
实施例4 | 酸甜适宜,无异味 |
实施例5 | 酸甜适宜,无异味 |
对比例1 | 酸甜适宜,有涩味 |
对比例2 | 酸味较淡,无异味 |
对比例3 | 酸味较浓,无异味 |
对比例4 | 酸味较淡,无异味 |
对比例5 | 酸甜适宜,无异味 |
市售 | 酸甜适宜,有涩味 |
Claims (10)
Priority Applications (1)
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CN103768011A (zh) * | 2012-10-23 | 2014-05-07 | 天津药物研究院 | 福多司坦注射剂及其制备方法 |
CN106361689A (zh) * | 2016-09-24 | 2017-02-01 | 北京万全德众医药生物技术有限公司 | 一种福多司坦口服溶液及其制备方法 |
CN112057418A (zh) * | 2020-09-24 | 2020-12-11 | 广州帝奇医药技术有限公司 | 一种福多司坦口服液及其制备方法 |
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CN103768011A (zh) * | 2012-10-23 | 2014-05-07 | 天津药物研究院 | 福多司坦注射剂及其制备方法 |
CN106361689A (zh) * | 2016-09-24 | 2017-02-01 | 北京万全德众医药生物技术有限公司 | 一种福多司坦口服溶液及其制备方法 |
CN112057418A (zh) * | 2020-09-24 | 2020-12-11 | 广州帝奇医药技术有限公司 | 一种福多司坦口服液及其制备方法 |
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