CN113811302A - 激酶抑制剂的用途 - Google Patents
激酶抑制剂的用途 Download PDFInfo
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- CN113811302A CN113811302A CN202080033803.0A CN202080033803A CN113811302A CN 113811302 A CN113811302 A CN 113811302A CN 202080033803 A CN202080033803 A CN 202080033803A CN 113811302 A CN113811302 A CN 113811302A
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- heterocyclic group
- nitrogen
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- antineoplastic agents
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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Abstract
本发明涉及一种CDK4/6激酶抑制剂的用途。具体地涉及式(I’)所示化合物、其药学上可接受的盐或其晶型在制备用于治疗胸腺瘤的药物中的用途。
Description
PCT国内申请，说明书已公开。
Claims (15)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910378887 | 2019-05-08 | ||
| CN2019103788870 | 2019-05-08 | ||
| CN2019109062449 | 2019-09-24 | ||
| CN201910906244 | 2019-09-24 | ||
| PCT/CN2020/088874 WO2020224609A1 (zh) | 2019-05-08 | 2020-05-07 | 激酶抑制剂的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113811302A true CN113811302A (zh) | 2021-12-17 |
| CN113811302B CN113811302B (zh) | 2023-12-29 |
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| CN202080033803.0A Active CN113811302B (zh) | 2019-05-08 | 2020-05-07 | 激酶抑制剂的用途 |
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| Country | Link |
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| CN (1) | CN113811302B (zh) |
| WO (1) | WO2020224609A1 (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116710095A (zh) * | 2020-12-31 | 2023-09-05 | 轩竹生物科技股份有限公司 | 一种治疗癌症的药物组合物 |
| CN114748479B (zh) * | 2021-01-08 | 2023-10-20 | 轩竹生物科技股份有限公司 | 一种预防和/或治疗癌症的药物组合物 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010106028A1 (en) * | 2009-03-20 | 2010-09-23 | Nerviano Medical Sciences S.R.L. | Use of a kinase inhibitor for the treatment of thymoma |
| WO2015101293A1 (zh) * | 2013-12-31 | 2015-07-09 | 山东轩竹医药科技有限公司 | 激酶抑制剂及其用途 |
| WO2016040858A1 (en) * | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| WO2019144759A1 (zh) * | 2018-01-29 | 2019-08-01 | 海南轩竹医药科技有限公司 | 靶向cdk4/6激酶抑制剂的晶型 |
-
2020
- 2020-05-07 CN CN202080033803.0A patent/CN113811302B/zh active Active
- 2020-05-07 WO PCT/CN2020/088874 patent/WO2020224609A1/zh active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010106028A1 (en) * | 2009-03-20 | 2010-09-23 | Nerviano Medical Sciences S.R.L. | Use of a kinase inhibitor for the treatment of thymoma |
| WO2015101293A1 (zh) * | 2013-12-31 | 2015-07-09 | 山东轩竹医药科技有限公司 | 激酶抑制剂及其用途 |
| WO2016040858A1 (en) * | 2014-09-12 | 2016-03-17 | G1 Therapeutics, Inc. | Combinations and dosing regimes to treat rb-positive tumors |
| WO2019144759A1 (zh) * | 2018-01-29 | 2019-08-01 | 海南轩竹医药科技有限公司 | 靶向cdk4/6激酶抑制剂的晶型 |
Non-Patent Citations (1)
| Title |
|---|
| SCOTT W. AESIF等: "Loss of p16INK4AExpression and Homozygous CDKN2A Deletion Are Associated with Worse Outcome and Younger Age in Thymic Carcinomas", 《JOURNAL OF THORACIC ONCOLOGY》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020224609A1 (zh) | 2020-11-12 |
| CN113811302B (zh) | 2023-12-29 |
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