CN108633890A - A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene - Google Patents
A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene Download PDFInfo
- Publication number
- CN108633890A CN108633890A CN201810375753.9A CN201810375753A CN108633890A CN 108633890 A CN108633890 A CN 108633890A CN 201810375753 A CN201810375753 A CN 201810375753A CN 108633890 A CN108633890 A CN 108633890A
- Authority
- CN
- China
- Prior art keywords
- thiophene
- metconazole
- gloomy copper
- bactericidal composition
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene, invention has apparent synergistic effect using metconazole and the gloomy copper of thiophene as the composite bactericide of active ingredient, delay the generation of key drug resistance, and reduce production and application costs, can be used for the improvement of resistance disease.There is preferable control effect to wheat powdery mildew.
Description
Technical field
Present invention relates particularly to technical field of pesticide combination, and in particular to a kind of sterilization group containing metconazole Yu the gloomy copper of thiophene
Close object.
Background technology
Metconazole, a kind of fungicide, the mechanism of action inhibit with C-14 demethylation enzymes in feature ergosterol biosynthesis
Agent.Although the mechanism of action, as other triazole bactericidal agents, then difference is larger for activity profile.Two kinds of isomers have sterilization to live
Property, but Cis activity is higher than trans-.The antifungal spectrum of metconazole is very extensive, and activity is splendid.It applies to paddy in metconazole field
Class crop septoria musiva, fusarium and handle rest fungus, which plant disease, excellent effect.For metconazole compared with traditional biocide agent, dosage is extremely low and anti-
It controls cereal and plants sick range but very extensively, the crops such as suitable for crop and safety wheat, barley, oat, rye, triticale.Metconazole
To non-target organism low toxicity, dosage is low and bactericidal activity is high, and environment foreground is good.Controlling object metconazole is a kind of new, wide spectrum
Systemic fungicide.It is mainly used for preventing wheat septoria, fringe sickle-like bacteria, leaf rust, stripe rust, powdery mildew, glume blight；Barley
Short shape rust, powdery mildew, beak genuss；Rye beak genuss, leaf rust；Crown hull sugar, a triticale (wheat hybridizes with rye)
Leaf rust, septoria musiva.To Septoria and rust superior activity.Have both excellent protection and therapeutic effect.It is withered to the grain husk of wheat
Disease is especially effective, and it is all good to prevent, treat effect.
The gloomy copper of thiophene is thiazoles organic copper fungicide, mainly prevents bacterial blight of rice, bacterial stripe, the soft corruption of Chinese cabbage
Disease and bacterial wilt of tomato.High-efficiency broad spectrum, toxicity is low, safety and environmental protection, nuisanceless, to bacterial disease special efficacy, to fungal disease
Efficiently, stablize in acid condition, it can be with other combined use of pesticides.
It is the most effective means of controlling plant diseases using chemical agent.But it applies to long-term continuous high dose single
Chemical bactericide, be easy to cause the problems such as residual of medicament, environmental pollution and drug-resistant fungi develop.Rational chemistry
Bactericide compounded or mixture have expand fungicidal spectrum, improve control effect, extend the optimum period for applying fertilizer, reduce dosage, reduce poisoning,
The positive features such as residual, the generation for delaying drug resistance of fungi and development are reduced, bactericide compounded is to solve above-mentioned ask
One of the maximally efficient method of topic.Develop new product fungicide price is constantly soaring, and in contrast, exploitation with research efficiently,
Low toxicity, the compounding of low-residual and mixture have that small investment, the lead time is short and is paid attention to both at home and abroad, and increasing one after another develops
Dynamics.We filter out metconazole and are compounded with the gloomy copper of thiophene based on the indoor screening and field trials, have apparent
Synergistic effect.And it has not been reported so far about the bactericidal composition and application of metconazole and the compounding of the gloomy copper of thiophene.
Invention content
In order to overcome the problems of the above-mentioned prior art, a kind of Bactericidal composite containing metconazole Yu the gloomy copper of thiophene is provided
Object.
The technical solution that the present invention uses is：A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene, it is described
Bactericidal composition is compounded by metconazole and the gloomy copper of thiophene, remaining is adjunct ingredient, the quality of the trifloxystrobin and the gloomy copper of thiophene
Than being 1:40-40:1.
The mass ratio of the metconazole and the gloomy copper of thiophene is 1:2.
The gross mass of the metconazole and the gloomy copper of thiophene accounts for the 1-40% of entire Bactericidal composite amount of substance.
The gross mass of the metconazole and the gloomy copper of thiophene accounts for the 30% of entire Bactericidal composite amount of substance.
The bactericidal composition be missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion,
One kind in granula, microcapsule formulations.
The adjunct ingredient is dispersant, antifreezing agent, solvent, synergist, thickener, antifoaming agent etc..
The beneficial effects of the invention are as follows：The present invention provides a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene, hair
It is bright that there is apparent synergistic effect as the composite bactericide of active ingredient using metconazole and the gloomy copper of thiophene, delay the production of key drug resistance
It is raw, and production and application costs are reduced, it can be used for the improvement of resistance disease.There is preferable prevention to wheat powdery mildew
Effect.
Specific implementation mode
With reference to embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention,
It is not limitation of the invention.
Test objective：
It is entrusted by Zhejiang east wind Chemical Co., Ltd., using pot-spraying method, test metconazole, the gloomy copper of thiophene, metconazole
The gloomy copper of thiophene (1:2) whether 3 medicaments have synergistic effect after determining pharmacy mix to the Indoor antibacterial activity of wheat powdery mildew, are
Field trial and in next step research and development provide foundation.
Experimental condition
Pot experiment condition
For trying pathogen：Wheat powdery mildew (Erysiphe graminis) (strain is laboratory storage culture strain).
For trying bacterium condition of culture
Wheat powdery mildew is by wheat seedling live body host indoor propagation conservation all the year round.Condition of culture:It is 18~22 DEG C, relatively wet
It is cultivated in 80% or so controllable greenhouses of degree.
For trying crop cultivation
Broadcast sowing the wheat seed of vernalization, culture to 2 leaves in diameter 4cm cuvettes with minishanny in 18 DEG C~22 DEG C greenhouses
Phase is spare.
Experimental design
Reagent
Test medicine
The gloomy copper TC of 95% metconazole TC, 92% thiophene (offer of Zhejiang east wind Chemical Co., Ltd.)
Other reagents：N,N-Dimethylformamide (purchase of Shanghai reagent shop).
Test process
Dosage is arranged
1 wheat powdery mildew test dose of table designs
Experiment repeats：Each processing sets 4 repetitions.
Processing mode
Processing time
Testing time：Wheat powdery mildew：On March 27th, 2018.
Control time：Wheat powdery mildew：On April 2nd, 2018.
Use instrument and administrated method
Liquid-transfering gun, card punch (internal diameter 5mm), Plating
Test method
Reference《The 4th part of farm-chemical indoor determination test rule fungicide：It prevents wheat powdery mildew and tests pot-culture method》
The test method of middle wheat powdery mildew carries out bioassay：Artificial infection is carried out after 24 hours in medication.To fall ill wheat leaf
The Powdery Mildew Fresh spores that on piece generates in for 24 hours uniformly are shaken off to be inoculated on 2 leaf phase potting wheat seedlings of processing.It is subsequently placed in
It 18~22 DEG C, cultivates in 80% or so controllable greenhouse of relative humidity, classification tune can be carried out after 6 days blank control stable diseases
It looks into.
Data survey and statistical analysis
Wheat powdery mildew investigation method
The investigation method and grade scale of wheat powdery mildew：
0 grade：It is disease-free；
1 grade：Lesion area accounts for 5% or less full wafer leaf area；
3 grades：Lesion area accounts for the 6%~15% of full wafer leaf area；
5 grades：Lesion area accounts for the 16%~25% of full wafer leaf area；
7 grades：Lesion area accounts for the 26%~50% of full wafer leaf area；
9 grades：Lesion area accounts for 50% or more of full wafer leaf area.
Computational methods
According to survey data, the disease index and control effect of each processing are calculated.
Disease index is calculated by formula (1), and result of calculation retains 2 significant digits：
In formula：X-disease index；Ni-sick the numbers of sheets at different levels；I-is with respect to value of series；N-investigation total number of sheets.
Control effect is calculated by formula (2)：
In formula：P-control effect, unit are percentage (%)；CK-blank control disease index；PT-chemicals treatment disease
Feelings index.
Isolated test investigation method
A bacterium colony diameter is measured perpendicularly using the crisscross method, takes its average value, and bacterium is calculated after deducting bacteria cake diameter
It is born long diameter.
Data statistic analysis：
According to investigation result, each concentration for the treatment of is calculated to the mycelial growth inhibition rate for trying target bacterium by formula (1), (2),
Unit is percentage (%), and result of calculation retains 2 significant digits.
D=D1-D2·················(1)
In formula：D-bacterium colony increases diameter；D1- colony diameter；D2- bacteria cake diameter.
I=(D0-Dt)×100/D0···········(2)
In formula：I-mycelial growth inhibition rate；D0- blank control bacterium colony increases diameter；Dt- chemicals treatment bacterium colony increases straight
Diameter.
Statistical analysis
Make regression analysis according to each drug concentration logarithm and corresponding mycelial growth inhibition rate probit value, calculates each medicament
EC50、EC90, 95% confidence limit.The co-toxicity coefficient (CTC) of mixture is calculated according still further to Sun Yunpei's Method.The compounding agent tables of CTC >=120
Existing synergy；The compounding agents of CTC≤80 show antagonism；80 ＜ CTC ＜, 120 compounding agents show as being added.
As a result with analysis
Wheat in wheat powdery mildew experiment is estimated to downgrade at 30%, 1000mg/L within 6 days after metconazole 2000mg/L processing
12% is downgraded after downgrading within 6 days after reason 20%, 500mg/L processing within 6 days；Also there is Huang in the wheat separately handled through high dose in metconazole
Brown spot symptom of chemical damage.Through the gloomy copper of mixture metconazole thiophene (1:2) the wheat symptom handled is slightly lighter than single dose metconazole.
From test medicament metconazole, the gloomy copper of thiophene and the gloomy copper of metconazole thiophene (1:2) inhibiting rate of wheat powdery mildew is calculated
Go out regression equation, related coefficient, EC50And EC90Value concrete outcome see the table below 2, and specific coefficient of synergism is shown in Table 3：
2 metconazole of table, the gloomy copper of thiophene and the gloomy copper of metconazole thiophene (1:2) wheat powdery mildew result is prevented
The EC that can must test medicament to testing target wheat powdery mildew is arranged from table 250Value calculates each mixed medicament to corresponding
The co-toxicity coefficient of target is tested, specific each mixed medicament is shown in Table 3 to the co-toxicity coefficient for accordingly testing target.
Table 3 uses medicament with and measures synergistic effect situation to accordingly testing target plate
The mixed medicament with synergistic effect is as can be seen from Table 3：Metconazole：Gloomy copper=1 of thiophene：2 prevention wheat white powder
Disease.
Interpretation of result and discussion
The metconazole from the point of view of test result：Gloomy copper=1 of thiophene：2 prevention wheat powdery mildews have synergistic effect.
Attached initial data
1 metconazole of table, the gloomy copper of thiophene and the gloomy copper of metconazole thiophene (1:2) prevention wheat powdery mildew test result (after medicine 6 days)
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation
Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art
Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications
It should be regarded as protection scope of the present invention.
Claims (5)
1. a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene, which is characterized in that the bactericidal composition is by metconazole
It is compounded with the gloomy copper of thiophene, remaining is adjunct ingredient, and the mass ratio of the trifloxystrobin and the gloomy copper of thiophene is 1:40-40:1.
2. a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene according to claim 1, which is characterized in that described
The mass ratio of metconazole and the gloomy copper of thiophene is 1:2.
3. a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene according to claim 1, which is characterized in that described
The gross mass of metconazole and the gloomy copper of thiophene accounts for the 1-40% of entire Bactericidal composite amount of substance.
4. a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene according to claim 3, which is characterized in that described
The gross mass of metconazole and the gloomy copper of thiophene accounts for the 30% of entire Bactericidal composite amount of substance.
5. a kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene according to claim 1, which is characterized in that described
Bactericidal composition is in missible oil, suspending agent, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations
One kind.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810375753.9A CN108633890A (en) | 2018-04-25 | 2018-04-25 | A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810375753.9A CN108633890A (en) | 2018-04-25 | 2018-04-25 | A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108633890A true CN108633890A (en) | 2018-10-12 |
Family
ID=63747327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810375753.9A Pending CN108633890A (en) | 2018-04-25 | 2018-04-25 | A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108633890A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103798251A (en) * | 2014-02-18 | 2014-05-21 | 中国水稻研究所 | Compound pesticide containing triazolone and Saisentong and application thereof |
| CN104770373A (en) * | 2015-04-17 | 2015-07-15 | 浙江海正化工股份有限公司 | Sterilization composition containing quinolinone and metconazole |
-
2018
- 2018-04-25 CN CN201810375753.9A patent/CN108633890A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103798251A (en) * | 2014-02-18 | 2014-05-21 | 中国水稻研究所 | Compound pesticide containing triazolone and Saisentong and application thereof |
| CN104770373A (en) * | 2015-04-17 | 2015-07-15 | 浙江海正化工股份有限公司 | Sterilization composition containing quinolinone and metconazole |
Non-Patent Citations (2)
| Title |
|---|
| 何莲等: ""新型杀菌剂叶菌唑对小麦几种病害的室内毒力测定及应用"", 《农药》 * |
| 张玉华: "《小麦病虫害原色图谱》", 30 June 2017, 河南科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106973907A (en) | A kind of composition pesticide containing copper 8-hydroxyquinolinate and kasugarnycin and its application | |
| CN109805018A (en) | A kind of Fungicidal composition and application | |
| CN104872155A (en) | Compound bactericide capable of preventing and treating rice blast | |
| CN106982844B (en) | A kind of agricultural bactericidal composition of Bao Han famoxadones and hymexazol | |
| CN107212011B (en) | A kind of bactericidal composition for preventing and treating crop disease | |
| CN108294014A (en) | A kind of seed coat agent and the preparation method and application thereof of prevention root rot | |
| CN107318853A (en) | Fertilizer granules and application containing metconazole | |
| CN107018979A (en) | Bactericidal composition containing Chinese yam polysaccharide and benzo alkene fluorine bacterium azoles | |
| CN103081920B (en) | Sterilizing composition containing penconazole | |
| CN101703057B (en) | Agricultural germicide composite containing famoxadone | |
| CN104094942A (en) | Pesticide composition containing 2-cyano-3-amino-3-phenylacrylic acetate and hymexazol | |
| CN104770373A (en) | Sterilization composition containing quinolinone and metconazole | |
| CN108651473A (en) | The effectively fertilizer granules of prevention soil-borne disease and plant disease | |
| CN108770858A (en) | Pyraclostrobin is being prepared with probenazole for the purposes in preventing the fungicide of the plant disease caused by Rhizoctonia cerealis | |
| CN104115869B (en) | A kind of ternary built pesticide containing Copper hydrate, trifloxystrobin and Tebuconazole | |
| CN108633890A (en) | A kind of bactericidal composition containing metconazole Yu the gloomy copper of thiophene | |
| CN107242242A (en) | Bactericidal composition comprising folpet and prothioconazoles | |
| CN108432787A (en) | A kind of bactericidal composition containing thiophanate methyl Yu the gloomy copper of thiophene | |
| CN108184864A (en) | A kind of complex composition and its application containing fluorine thiazole pyrrole ethyl ketone and frutus cnidii | |
| CN103651396A (en) | Sterilization composition | |
| CN114982770B (en) | Composition for preventing and treating sesame wilt and application thereof | |
| CN109418273A (en) | A kind of bactericidal composition | |
| CN107223661A (en) | A kind of composition pesticide containing DCPTA | |
| CN108669082A (en) | A kind of bactericidal composition containing probenazole Yu the gloomy copper of thiophene | |
| CN108522520A (en) | A kind of bactericidal composition containing trifloxystrobin Yu the gloomy copper of thiophene |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |