CN106977466A - 一种高堆密度格列吡嗪的结晶制备方法 - Google Patents
一种高堆密度格列吡嗪的结晶制备方法 Download PDFInfo
- Publication number
- CN106977466A CN106977466A CN201710168249.7A CN201710168249A CN106977466A CN 106977466 A CN106977466 A CN 106977466A CN 201710168249 A CN201710168249 A CN 201710168249A CN 106977466 A CN106977466 A CN 106977466A
- Authority
- CN
- China
- Prior art keywords
- glipizide
- heap density
- preparation
- solvent
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710168249.7A CN106977466B (zh) | 2017-03-21 | 2017-03-21 | 一种高堆密度格列吡嗪的结晶制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710168249.7A CN106977466B (zh) | 2017-03-21 | 2017-03-21 | 一种高堆密度格列吡嗪的结晶制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106977466A true CN106977466A (zh) | 2017-07-25 |
CN106977466B CN106977466B (zh) | 2018-07-31 |
Family
ID=59339568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710168249.7A Active CN106977466B (zh) | 2017-03-21 | 2017-03-21 | 一种高堆密度格列吡嗪的结晶制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106977466B (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102993106A (zh) * | 2012-12-24 | 2013-03-27 | 武汉武药制药有限公司 | 格列吡嗪的合成新路线 |
CN104086490A (zh) * | 2014-07-17 | 2014-10-08 | 徐小强 | 一种格列吡嗪化合物及含有该化合物的药物组合物及其制备方法 |
CN106187921A (zh) * | 2016-07-09 | 2016-12-07 | 威海迪素制药有限公司 | 一种格列吡嗪结晶的制备方法 |
-
2017
- 2017-03-21 CN CN201710168249.7A patent/CN106977466B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102993106A (zh) * | 2012-12-24 | 2013-03-27 | 武汉武药制药有限公司 | 格列吡嗪的合成新路线 |
CN104086490A (zh) * | 2014-07-17 | 2014-10-08 | 徐小强 | 一种格列吡嗪化合物及含有该化合物的药物组合物及其制备方法 |
CN106187921A (zh) * | 2016-07-09 | 2016-12-07 | 威海迪素制药有限公司 | 一种格列吡嗪结晶的制备方法 |
Non-Patent Citations (2)
Title |
---|
KUMAR DINESH,等: "Spherical crystallization of glipizide for improvement of micrometric properties", 《INTERNATIONAL JOURNAL OF PHARMACY AND LIFE SCIENCES》 * |
刘炳朋,等: "格列吡嗪的合成", 《中国医药工业杂志》 * |
Also Published As
Publication number | Publication date |
---|---|
CN106977466B (zh) | 2018-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101439022B (zh) | 一种克林霉素磷酸酯粉针剂原料药的制备方法 | |
CN106397249A (zh) | 一种高稳定性lcz696结晶粉末及其制备方法 | |
WO2021227146A1 (zh) | N-[8-(2-羟基苯甲酰基)氨基]辛酸一钾晶型化合物、制备方法及用途 | |
CN106977466B (zh) | 一种高堆密度格列吡嗪的结晶制备方法 | |
CN102285970B (zh) | 一种埃索美拉唑化合物、制备方法及其药物组合物 | |
CN106187921B (zh) | 一种格列吡嗪结晶的制备方法 | |
CN103735544B (zh) | 一种维达列汀/盐酸二甲双胍复方制剂的制备工艺 | |
CN103565806A (zh) | 一种罗氟司特口服制剂及其制备方法 | |
CN103214382B (zh) | 一种盐酸甲氯芬酯化合物及其药物组合物 | |
CN101647781B (zh) | 注射用磷酸川芎嗪粉针的制备方法 | |
CN106397409B (zh) | 一种坎地沙坦酯晶型i球形结晶的制备方法 | |
CN103159737B (zh) | 一种埃索美拉唑钠化合物及药物组合物 | |
CN104211693B (zh) | 一种利伐沙班晶型及其制备方法与用途 | |
CN103044509B (zh) | γ-胞嘧啶核苷-5’-三磷酸二钠结晶化合物、其制备方法及其药物组合物 | |
CN102516338B (zh) | 一种卡培他滨化合物、其药物组合物及其制备方法 | |
CN104151324B (zh) | 一种溶媒结晶法制备氨苄西林钠的方法 | |
CN111057038A (zh) | 一种司替戊醇新晶型 | |
CN113116837B (zh) | 一种盐酸吡格列酮缓释片及其制备方法 | |
CN107814815A (zh) | 一种甲磺酸溴隐亭新晶型 | |
CN103565753A (zh) | 盐酸氨溴索颗粒及其制备方法 | |
CN115212171B (zh) | 一种替格瑞洛缓释微丸及包含该缓释微丸的药物制剂 | |
CN105106129A (zh) | 一种治疗消化***疾病的药物兰索拉唑组合物颗粒剂 | |
CN106432021A (zh) | 一种福多司坦结晶的制备方法 | |
CN102532122A (zh) | 酒石酸罗格列酮的制备方法 | |
WO2015149638A1 (zh) | 达比加群酯甲磺酸盐晶型、其制备方法以及药物组合物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20191023 Address after: 264205 Guangzhou East Road South and an East Road East, Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Co-patentee after: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. Patentee after: Dijia Pharmaceutical Group Co.,Ltd. Co-patentee after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Address before: Tianrun road Wendeng Economic Development Zone in Weihai City, Shandong Province, No. 268 264205 Co-patentee before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Patentee before: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210722 Address after: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Patentee after: Dijia Pharmaceutical Group Co.,Ltd. Patentee after: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Address before: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Patentee before: Dijia Pharmaceutical Group Co.,Ltd. Patentee before: WEIHAI DISU PHARMACEUTICAL Co.,Ltd. Patentee before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. Effective date of registration: 20210722 Address after: 264205 268 Tianrun Road, Wendeng economic and Technological Development Zone, Weihai, Shandong Patentee after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 Wendeng economic and Technological Development Zone, Weihai City, Shandong Province Patentee before: Dijia Pharmaceutical Group Co.,Ltd. Patentee before: DISHA PHARMACEUTICAL GROUP Co.,Ltd. |
|
CP03 | Change of name, title or address | ||
CP03 | Change of name, title or address |
Address after: No. 268, Tianrun Road, Wendeng Economic and Technological Development Zone, Weihai City, Shandong Province, 264200 Patentee after: Dijia Pharmaceutical Group Co.,Ltd. Address before: 264205 268 Tianrun Road, Wendeng economic and Technological Development Zone, Weihai, Shandong Patentee before: Dijia Pharmaceutical Group Co.,Ltd. |