CN106478784A - 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 - Google Patents
用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 Download PDFInfo
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- CN106478784A CN106478784A CN201610854932.1A CN201610854932A CN106478784A CN 106478784 A CN106478784 A CN 106478784A CN 201610854932 A CN201610854932 A CN 201610854932A CN 106478784 A CN106478784 A CN 106478784A
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57442—Specifically defined cancers of the uterus and endometrial
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
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- Hospice & Palliative Care (AREA)
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- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Description
HPV16-1 | KCDSTLRLCVQSTHVDIRTLE | SEQ ID NO:1 |
HPV16-2 | PTLHEYMLDLQPETTDLYCYEQLNDSSEEE | SEQ ID NO:2 |
HPV16-3 | LNDSSEEEDEIDGPAGQAEPDRAH | SEQ ID NO:3 |
HPV18-1 | IDGVNHQHLPARRAEPQR | SEQ ID NO:4 |
HPV18-2 | SDSEEENDEIDGVNHQHLPARRAEPQRH | SEQ ID NO:5 |
SEQ ID NO:1 | SEQ ID NO:2 | SEQ ID NO:3 | SEQ ID NO:4 | SEQ ID NO:5 | |
平均值 | 0.292 | 0.279 | 0.382 | 0.301 | 0.383 |
标准方差 | 0.098 | 0.100 | 0.111 | 0.076 | 0.111 |
cutoff | 0.487 | 0.480 | 0.604 | 0.452 | 0.605 |
病理 | 人数(10) | SEQ ID NO:1阳性 | SEQ ID NO:3阳性 | SEQ ID NO:5阳性 |
CINⅠ | 2 | 2 | 1 | 1 |
CINⅡ,Ⅲ | 7 | 4 | 5 | 5 |
*** | 1 | 0 | 1 | 1 |
Claims (10)
Priority Applications (1)
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CN201610854932.1A CN106478784B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
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CN201310056516.3A CN104004067B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
CN201610854932.1A CN106478784B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
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CN201310056516.3A Division CN104004067B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
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Publication Number | Publication Date |
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CN106478784A true CN106478784A (zh) | 2017-03-08 |
CN106478784B CN106478784B (zh) | 2019-10-25 |
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CN201610854355.6A Active CN106632617B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
CN201310056516.3A Active CN104004067B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
CN201610854932.1A Active CN106478784B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
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CN201310056516.3A Active CN104004067B (zh) | 2013-02-22 | 2013-02-22 | 用于检测抗人***瘤病毒抗体的抗原及相关免疫检测试剂盒 |
Country Status (2)
Country | Link |
---|---|
CN (3) | CN106632617B (zh) |
WO (1) | WO2014127741A1 (zh) |
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CN103254307A (zh) * | 2012-02-16 | 2013-08-21 | 艾托金生物医药(苏州)有限公司 | Hpv18e7单克隆抗体、相关杂交瘤细胞株和应用 |
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