CN104547555A - Traditional Chinese medicinal composition having functions of enriching yin and nourishing kidney as well as preparation method and application of traditional Chinese medicinal composition - Google Patents
Traditional Chinese medicinal composition having functions of enriching yin and nourishing kidney as well as preparation method and application of traditional Chinese medicinal composition Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/50—Methods involving additional extraction steps
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Abstract
The invention discloses a traditional Chinese medicinal composition having functions of enriching yin and nourishing kidney as well as a preparation method and application of the traditional Chinese medicinal composition. The active ingredient of the traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 1-5 parts of fruit of Chinese wolfberry, 1-5 parts of black sesame, 1-5 parts of mulberry, 1-5 parts of rhizoma polygonati and 1-7 parts of Chinese yam. The method comprises the steps of weighing the raw materials and decocting the raw materials together with water. According to the traditional Chinese medicinal composition disclosed by the invention, the various components take mutual synergic effect so as to achieve the functions of enriching yin and nourishing kidney, and the traditional Chinese medicinal composition is especially suitable for conditioning the deficiency of kidney and yin causing sub-health status; meanwhile, the traditional Chinese medicinal composition can be also used for relieving dizziness, headache, soreness and weakness of waist and knees, dry mouth and throat, dysphoria in chestpalms-soles and other symptoms; and in addition, since various components are prepared from both medicinal and dietary plants, the composition is sufficient in source, free from any toxic and side effects, and suitable for being taken for a long term.
Description
Technical field
The invention belongs to field of food, particularly a kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney and its preparation method and application.
Background technology
Cream side, also known as soft extract, soft extracts, be that the prepared slices of Chinese crude drugs decoct by one repeatedly, remove slag extracting juice, through evaporation and concentration, the semifluid shape dosage form that sugaring or Mel etc. are made.The adaptation population of cream side is long-term chronic kidney disease, after being ill, Post operation, puerperal patient, person in middle and old age valetudinarian.And " sub-health state " crowd of modern society, be particularly suitable for the conditioning of cream side.Every physico-chemical examination may be completely normal, also may some index be in " borderline state ", but and non-direction disease prompting. this " subhealth state " state, often pasts medical help in doctor trained in Western medicine, and often can reach beyond thought effect by the conditioning of cream side.
Most scholar thinks that the formation of sub-health state causes due to the imbalance of the five internal organs negative and positive of qi and blood, and to suffer from a deficiency of the kidney be that human five internal organs's negative and positive of qi and blood is unbalance basic.Kidney yin have promote body moist, quiet, be shaped and restrict function; Kidney yin arrives internal organs, meridians, body, official's key of whole body, then become the moon of these internal organs, meridians, body, official's key, promote and regulate the functional activity of whole body, deficiency of the kidney yin is the whole body deficiency of YIN then, the yin and yang imbalance of the five internal organs, the various discomfort of whole body (i.e. sub-health state) very then disease also occurs thereupon, show as the syndrome of deficiency of kidney yin of sub-health state: dizzy, headache, soreness of the waist and knees, dry mouth and throat, the symptoms such as dysphoria with feverish sensation in the chest palms and soles.
The traditional multiplex Radix Ginseng of tonification side's medicine, Cornu Cervi Pantotrichum and so on, but YANG invigorating QI invigorating emphasized by these medicines more, the most common cream side's such as the primordial QI reinforcing cream primary efficacy of existing market is then blood-enriching face-nourishing, and other the kidney invigorating cream Fang Jun is for deficiency of kidney-YANG syndrome, effect emphasizes kidney invigorating and YANG supporting, all not for syndrome of deficiency of kidney yin.
Summary of the invention
Based on this, the object of the present invention is to provide a kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney.
The concrete technical scheme solved the problems of the technologies described above is as follows:
Have a Chinese medicine composition for effect of nourishing Yin and invigorating kidney, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Fructus Lycii 1-5 part, Semen Sesami Nigrum 1-5 part, Fructus Mori 1-5 part, Rhizoma Polygonati 1-5 part, Rhizoma Dioscoreae 1-7 part.
Wherein in some embodiments, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Fructus Lycii 1-3 part, Semen Sesami Nigrum 2-4 part, Fructus Mori 2-4 part, Rhizoma Polygonati 2-4 part, Rhizoma Dioscoreae 4-6 part.
Another object of the present invention is to provide a kind of preparation method with the Chinese medicine composition of effect of nourishing Yin and invigorating kidney, comprise the steps: to take Fructus Lycii, Semen Sesami Nigrum, Fructus Mori, Rhizoma Polygonati and Rhizoma Dioscoreae, decoct with water.
Wherein in some embodiments, the addition of described water is 8-12 times of medical material amount.
Wherein in some embodiments, also comprise concentrated.
Wherein in some embodiments, described simmer down to: at the decocting liquid decocting with water rear gained is concentrated into 75-85 DEG C, relative density is 1.12 ± 0.02.
Another object of the present invention is to provide above-mentioned Chinese medicine composition preparing the application in the health product or food with effect of nourishing Yin and invigorating kidney.
Another object of the present invention is to provide a kind of nourishing yin and tonifying kidney, the active component of described nourishing yin and tonifying kidney is above-mentioned Chinese medicine composition.
Wherein in some embodiments, described nourishing yin and tonifying kidney is aided with acceptable adjuvant on unguentum by above-mentioned Chinese medicine composition and is prepared from.
Wherein in some embodiments, described nourishing yin and tonifying kidney is mainly prepared from by above-mentioned Chinese medicine composition 20-30wt%, white sugar 28-36wt% and glucose syrup 38-48wt%.
In nourishing yin and tonifying kidney of the present invention in Chinese medicine composition the property of medicine of each medical material and adjuvant and principle as follows:
Fructus Lycii: medicine-food two-purpose medical material, records in 2010 editions " Chinese Pharmacopoeias ", and sweet in the mouth, property are flat.Return liver, kidney channel.Energy nourishing the liver and kidney, replenishing vital essence to improve eyesight.For soreness of waist and knee joint, asthenia damage of essence, vertigo and tinnitus, impotence and seminal emission.
Semen Sesami Nigrum: the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return liver, kidney, large intestine channel.Energy invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry.For dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, blood and essence asthenia.
Fructus Mori: the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, acid, cold in nature.GUIXIN, liver, kidney channel.Energy nourishing YIN and supplementing blood, promotes the production of body fluid and moisturizes.For the hepatic and renal YIN deficiency, vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, when wound is thirsty, interior-heat is quenched one's thirst.
Rhizoma Polygonati: the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return spleen, lung, kidney channel.Energy enriching yin and nourishing kidney, spleen invigorating, lung moistening.For asthenia of essence and blood, soreness of the waist and knees, early whitening of beard and hair, interior-heat is quenched one's thirst, fatigue and asthenia, deficiency of stomach-Yin, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, chronic cough hemoptysis.
Rhizoma Dioscoreae: the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return spleen, lung, kidney channel.Energy the kidney invigorating arresting seminal emission, spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney.
White sugar: sweet in the mouth, property is put down, nontoxic.Enter spleen, lung meridian.Energy nourishing YIN and moistening the lung, and middle strengthening the spleen, promoting the production of body fluid to quench thirst, throat, relieves the effect of alcohol.For insufficiency of the spleen stomachache.
Nourishing yin and tonifying kidney of the present invention, by adding the mutual synergism of Fructus Lycii, Semen Sesami Nigrum, Fructus Mori, Rhizoma Polygonati, Rhizoma Dioscoreae, reaches the merit of enriching yin and nourishing kidney, can alleviate the dizziness caused by deficiency of the kidney yin, headache, soreness of the waist and knees, dry mouth and throat, the symptoms such as dysphoria with feverish sensation in the chest palms and soles.
Chinese medicine composition with effect of nourishing Yin and invigorating kidney of the present invention and its preparation method and application has the following advantages and beneficial effect:
(1) the present invention is through a large amount of experiment of inventor and research, draw the Chinese medicine composition with effect of nourishing Yin and invigorating kidney, and determine best composition and the proportioning thereof of said composition, in described compositions, each component is worked in coordination with mutually, jointly reach the merit of enriching yin and nourishing kidney, especially for the syndrome of deficiency of kidney yin of conditioning subhealth state; Also can alleviate the dizziness caused by deficiency of the kidney yin, headache, soreness of the waist and knees, dry mouth and throat, the symptoms such as dysphoria with feverish sensation in the chest palms and soles simultaneously; In addition, in described compositions, each component is the plant of integration of edible and medicinal herbs, and source is sufficient, without any side effects, is applicable to long-term taking;
(2) preparation method of the present invention is simple, is applicable to large-scale production.
Detailed description of the invention
Below with reference to specific embodiment, the present invention will be further described.
Embodiment 1
A kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney described in the present embodiment, its effective ingredient is prepared from by the raw material of following weight:
Fructus Lycii 30 grams, Semen Sesami Nigrum 45 grams, 45 grams, Fructus Mori, Rhizoma Polygonati 45 grams, Rhizoma Dioscoreae 75 grams.
The preparation method of described Chinese medicine composition is as follows:
By above-mentioned weight, take Fructus Lycii, Semen Sesami Nigrum, Fructus Mori, Rhizoma Polygonati and Rhizoma Dioscoreae, decoct secondary, first time adds drinking water 2.4L, and timing from medicinal liquid boiling, decocts 3 hours, second time adds drinking water 2L, decocts 1.5 hours, merges twice water extraction decoction liquor, be evaporated to same medical material weight 2-3 water volume doubly, filter pressing, continues to be concentrated into same medical material weight water volume, about 240 milliliters, relative density is 1.12 ± 0.02 (80 DEG C), about 269 grams.
A kind of nourishing yin and tonifying kidney, is prepared from by following raw material:
Chinese medicine composition 269 grams (26.9%),
White sugar (sucrose) 320 grams (32%),
Glucose syrup 411 grams (41.1%).
The preparation method of above-mentioned nourishing yin and tonifying kidney is as follows:
(1) cream refining: get white sugar (sucrose), add suitable quantity of water, dissolves, filter, clear and bright syrup and Fructus Lycii, Semen Sesami Nigrum, Fructus Mori, Rhizoma Polygonati, Rhizoma Dioscoreae water extract merge refines 6-8 hour, obtains the clear paste that relative density is 1.20 ~ 1.37, for subsequent use.
(2) finished product: get above-mentioned clear paste and add liquid glucose and stir, boil, be cooled to 60 ~ 70 DEG C, fill and get final product.
Embodiment 2
A kind of nourishing yin and tonifying kidney described in the present embodiment, is prepared from by following raw material:
Chinese medicine composition (obtained by embodiment 1): 200 grams (20%),
White sugar (sucrose): 350 grams (35%),
Glucose syrup: 450 grams (45%).
The preparation method of the nourishing yin and tonifying kidney containing Chinese medicine extract described in the present embodiment is identical with embodiment 1.
Embodiment 3
A kind of nourishing yin and tonifying kidney described in the present embodiment, is prepared from by following raw material:
Chinese medicine composition (obtained by embodiment 1): 300 grams (30%),
White sugar (sucrose): 300 grams (30%),
Glucose syrup: 400 grams (40%).
The preparation method of the nourishing yin and tonifying kidney containing Chinese medicine extract described in the present embodiment is identical with embodiment 1.
Embodiment 4
A kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney described in the present embodiment, its effective ingredient is prepared from by the raw material of following weight:
Fructus Lycii 30 grams, Semen Sesami Nigrum 30 grams, 30 grams, Fructus Mori, Rhizoma Polygonati 30 grams, Rhizoma Dioscoreae 30 grams.
Embodiment 5
A kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney described in the present embodiment, its effective ingredient is prepared from by the raw material of following weight:
Fructus Lycii 50 grams, Semen Sesami Nigrum 10 grams, 50 grams, Fructus Mori, Rhizoma Polygonati 10 grams, Rhizoma Dioscoreae 70 grams.
Comparative example 1
A kind of Chinese medicine composition of the present embodiment, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight:
Fructus Lycii 30 grams, Semen Sesami Nigrum 45 grams, 45 grams, Fructus Mori, Rhizoma Polygonati 45 grams.
Comparative example 2
A kind of Chinese medicine composition of the present embodiment, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight:
Fructus Lycii 30 grams, Semen Sesami Nigrum 8 grams, 45 grams, Fructus Mori, Rhizoma Polygonati 45 grams, Rhizoma Dioscoreae 75 grams.
Embodiment 6 Efficacy experiments
One, experiment purpose
By enriching yin and nourishing kidney effect of the nourishing yin and tonifying kidney obtained by relative analysis Evaluation operation example 1.
Two, experimental technique
1, experimental subject: mainly for sub-health state syndrome of deficiency of kidney yin person, occur dizziness, headache, soreness of the waist and knees, dry mouth and throat, dysphoria with feverish sensation in the chest palms and soles symptom 60 example, is divided into A, B, C, D tetra-groups, often organizes 15 people.
2, instructions of taking
A group: take nourishing yin and tonifying kidney described in embodiment 1, each serving with 15 grams, takes 2 every day;
B group: take not containing the unguentum of the Chinese medicine extract described in embodiment 1, each serving with 15 grams, take 2 every day;
C group: take the unguentum (wherein, the content of white sugar is identical with embodiment 1) containing Chinese medicine extract described in comparative example 1, each serving with 15 grams, take 2 every day;
D group: take the unguentum (wherein, the content of white sugar is identical with embodiment 1) containing Chinese medicine extract described in comparative example 2, each serving with 15 grams, take 2 every day.
Three, experimental result
Experimental result shows: after A group takes five days, and 11 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 4 people represent DeGrain; After taking two weeks continuously, 13 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles obviously alleviate, and 1 people represents that symptom alleviates, and 1 people represents DeGrain;
After B group takes five days, 1 people represents dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 14 people represent DeGrain; After taking two weeks continuously, 2 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 13 people represent DeGrain;
After C group takes five days, 6 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 9 people represent DeGrain; After taking two weeks continuously, 8 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 7 people represent DeGrain;
After D group takes five days, 8 people represent dizzy, headache, soreness of the waist and knees, dry mouth and throat, and the symptoms such as dysphoria with feverish sensation in the chest palms and soles alleviate, and 7 people represent DeGrain; After taking two weeks continuously, 10 people represent dizzy, and headache, soreness of the waist and knees, dry mouth and throat, the symptoms such as dysphoria with feverish sensation in the chest palms and soles obviously alleviate, and 3 people represent that symptom alleviates, and 2 people represent DeGrain.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (9)
1. one kind has the Chinese medicine composition of effect of nourishing Yin and invigorating kidney, it is characterized in that, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Fructus Lycii 1-5 part, Semen Sesami Nigrum 1-5 part, Fructus Mori 1-5 part, Rhizoma Polygonati 1-5 part, Rhizoma Dioscoreae 1-7 part.
2. a kind of Chinese medicine composition with effect of nourishing Yin and invigorating kidney according to claim 1, it is characterized in that, the effective ingredient of described Chinese medicine composition is prepared from by the raw material of following weight parts: Fructus Lycii 1-3 part, Semen Sesami Nigrum 2-4 part, Fructus Mori 2-4 part, Rhizoma Polygonati 2-4 part, Rhizoma Dioscoreae 4-6 part.
3. an a kind of preparation method with the Chinese medicine composition of effect of nourishing Yin and invigorating kidney as claimed in claim 1 or 2, is characterized in that, comprises the steps: to take Fructus Lycii, Semen Sesami Nigrum, Fructus Mori, Rhizoma Polygonati and Rhizoma Dioscoreae, decocts with water.
4. a kind of preparation method with the Chinese medicine composition of effect of nourishing Yin and invigorating kidney according to claim 3, is characterized in that, the addition of described water is 8-12 times of medical material amount.
5. a kind of preparation method with the Chinese medicine composition of effect of nourishing Yin and invigorating kidney according to claim 3 or 4, is characterized in that, also comprise concentrated.
6. a kind of preparation method with the Chinese medicine composition of effect of nourishing Yin and invigorating kidney according to claim 5, is characterized in that, described simmer down to: at the decocting liquid decocting with water rear gained is concentrated into 75-85 DEG C, relative density is 1.12 ± 0.02.
7. the Chinese medicine composition described in claim 1 or 2 is preparing the application in the health product or food with effect of nourishing Yin and invigorating kidney.
8. a nourishing yin and tonifying kidney, is characterized in that, the active component of described nourishing yin and tonifying kidney is the Chinese medicine composition described in claim 1 or 2.
9. a kind of nourishing yin and tonifying kidney according to claim 8, is characterized in that, described nourishing yin and tonifying kidney is mainly prepared from by Chinese medicine composition 20-30wt% as claimed in claim 1 or 2, white sugar 28-36wt% and glucose syrup 38-48wt%.
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