CN109966404A - A kind of rhizoma polygonati jujube composition and preparation method thereof - Google Patents
A kind of rhizoma polygonati jujube composition and preparation method thereof Download PDFInfo
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- CN109966404A CN109966404A CN201910240409.3A CN201910240409A CN109966404A CN 109966404 A CN109966404 A CN 109966404A CN 201910240409 A CN201910240409 A CN 201910240409A CN 109966404 A CN109966404 A CN 109966404A
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- 239000000203 mixture Substances 0.000 title claims abstract description 47
- 238000002360 preparation method Methods 0.000 title claims abstract description 31
- 240000008866 Ziziphus nummularia Species 0.000 title 1
- 241001247821 Ziziphus Species 0.000 claims abstract description 63
- 241000220317 Rosa Species 0.000 claims abstract description 40
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 39
- 210000000582 semen Anatomy 0.000 claims abstract description 37
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 36
- 240000000249 Morus alba Species 0.000 claims abstract description 35
- 239000000463 material Substances 0.000 claims abstract description 28
- 238000000034 method Methods 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 239000004615 ingredient Substances 0.000 claims abstract description 7
- 238000001035 drying Methods 0.000 claims description 28
- 239000002245 particle Substances 0.000 claims description 27
- 239000000843 powder Substances 0.000 claims description 26
- 239000011122 softwood Substances 0.000 claims description 19
- 230000001954 sterilising effect Effects 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 241000218231 Moraceae Species 0.000 claims description 6
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 6
- 229910052782 aluminium Inorganic materials 0.000 claims description 6
- 239000004411 aluminium Substances 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 6
- 238000009826 distribution Methods 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000005550 wet granulation Methods 0.000 claims description 5
- 239000000080 wetting agent Substances 0.000 claims description 5
- 241000894006 Bacteria Species 0.000 claims 1
- 239000003595 mist Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 18
- 210000003734 kidney Anatomy 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 230000006378 damage Effects 0.000 abstract description 3
- 238000004891 communication Methods 0.000 abstract description 2
- 238000004090 dissolution Methods 0.000 abstract description 2
- 230000035622 drinking Effects 0.000 abstract description 2
- 235000008216 herbs Nutrition 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 239000008280 blood Substances 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 235000013361 beverage Nutrition 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 239000000284 extract Substances 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 244000241838 Lycium barbarum Species 0.000 description 2
- 235000015459 Lycium barbarum Nutrition 0.000 description 2
- JAWMENYCRQKKJY-UHFFFAOYSA-N [3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-ylmethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]methanone Chemical compound N1N=NC=2CN(CCC=21)CC1=NOC2(C1)CCN(CC2)C(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F JAWMENYCRQKKJY-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000004356 Hysteria Diseases 0.000 description 1
- 235000015468 Lycium chinense Nutrition 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 241000207960 Pedaliaceae Species 0.000 description 1
- 241000756042 Polygonatum Species 0.000 description 1
- 241001468611 Polygonatum cyrtonema Species 0.000 description 1
- 241000219100 Rhamnaceae Species 0.000 description 1
- 244000000231 Sesamum indicum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 241000208292 Solanaceae Species 0.000 description 1
- 244000105017 Vicia sativa Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
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- 238000003745 diagnosis Methods 0.000 description 1
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- 239000012530 fluid Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 208000006278 hypochromic anemia Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
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- 210000004072 lung Anatomy 0.000 description 1
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- 230000001737 promoting effect Effects 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
- A23L25/30—Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P17/00—Drugs for dermatological disorders
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- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The present invention provides a kind of rhizoma polygonati jujube compositions and preparation method thereof, belong to integration of drinking and medicinal herbs field.Rhizoma polygonati jujube composition of the present invention prepares the ingredient that raw material includes following parts by weight: 10~15 parts of rhizoma polygonati, 10~15 parts of mulberry fruit, 8~12 parts of Semen sesami nigrum, 8~12 parts of fructus lycii, 10~15 parts of rose, 8~12 parts of jujube.Rhizoma polygonati jujube composition of the present invention has effects that excellent kidney tonifying, essence replenishing, blood-nourishing dark hair and by rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube scientific compatibility, and is free of auxiliary material, natural safety.The preparation method of rhizoma polygonati jujube composition of the present invention uses superfine communication technique, substantially increases the dissolution rate of medicinal material effective component, and low-temperature operation can be used in whole production process, avoids the destruction to effective component in raw material.
Description
Technical field
The invention belongs to integration of drinking and medicinal herbs field, it is related to a kind of rhizoma polygonati jujube composition and preparation method thereof, more particularly, to
It is a kind of to have effects that kidney tonifying, essence replenishing, rhizoma polygonati jujube composition of blood-nourishing dark hair and preparation method thereof.
Background technique
In recent years, as people's quality of life is higher and higher, food quality and safety is focused more on, on the market about health class
Product, mostly health food, and health food, production threshold are high, price is high, it is difficult to it is popular, therefore, be turned on health banner
The food such as plant source solid beverage come into being, but actual efficacy is had no mostly, and also contain more additive, when long
Between eat, be unfavorable for human health.In addition, need to be mentioned using water in the solid beverage preparation process of traditional plant source or alcohol extracting method mentions
The effective component in plant is taken, if CN201510072999.5 is when preparing a kind of yuenkanin extract compound solid beverage, is used
Water extraction extracts the effective component in Yuan root fruit block, and CN201610803225.X is preparing a kind of wolfberry fruit extract solid beverage
When, the effective component in fructus lycii is extracted using alcohol extracting method, but effective component cannot be extracted completely in this way, and after extraction
It must be concentrated, dry to remove solvent, complex process, and cause utilization rate of active components low.
Summary of the invention
In order to overcome the disadvantages mentioned above and deficiency of the prior art, the purpose of the present invention is to provide one kind to fill out with kidney tonifying
Essence, rhizoma polygonati jujube composition of blood-nourishing dark hair effect and preparation method thereof.
The object of the invention is achieved through the following technical solutions:
A kind of rhizoma polygonati jujube composition prepares the ingredient that raw material includes following parts by weight: 10~15 parts of rhizoma polygonati, mulberry fruit 10
~15 parts, 8~12 parts of Semen sesami nigrum, 8~12 parts of fructus lycii, 10~15 parts of rose, 8~12 parts of jujube, preferably 11 parts of rhizoma polygonati, mulberry
12 parts of mulberry, 10 parts of Semen sesami nigrum, 10 parts of fructus lycii, 12 parts of rose, 10 parts of jujube.
Rhizoma polygonati is liliaceous plant polygonatum kingianurn, rhizoma polygonati or the dry rhizome of polygonatum cyrtonema, has boosting qi and nourishing yin, invigorating the spleen, profit
The effect of lung, kidney-nourishing;Mulberries are the drying fruit ear of moraceae plants mulberry, have effects that nourishing yin and supplementing blood, fluid dryness, can be used to control
Treat the illnesss such as the deficiency of liver-yin and kidney-yin;Semen sesami nigrum is the dry mature seed of Pedaliaceae plant sesame, has nourishing liver and kidney, benefiting essence-blood, ease constipation
Dry effect can be used to treat the illnesss such as blood and essence asthenia;Fructus lycii is the dry mature fruit of Lycium barbarum L. of solanaceae, is had
It the effect of nourishing liver and kidney, benefiting shrewd head, can be used to treat the illnesss such as consumption consumptive loss, impotence and seminal emission, blood deficiency chlorosis;Rose is rose
The dry flower of common vetch section plant rose has effects that promoting qi circulation and removing obstruction in the collateral and blood, analgesic, can be used to treat stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, deficiency of food is vomitted
The illnesss such as evil, irregular menstruation, the pain of injury caused by falling and tumbling;Jujube is the dry mature fruit of Rhamnaceae plant jujube, has tonifying middle-Jiao and Qi, blood-nourishing
The effect of tranquilizing the mind, can be used to treat the illnesss such as spleen eating less, loose stool out of strength, hysteria of womam.Applicant compares this six kinds of raw materials
Various combination mode, as a result have been surprisingly found that, when rhizoma polygonati, mulberries, Semen sesami nigrum, fructus lycii, rose combine together with jujube,
And rhizoma polygonati is 10~15 parts by weight, mulberry fruit is 10~15 parts by weight, Semen sesami nigrum is 8~12 parts by weight, fructus lycii is 8~12 weight
Part, rose is when to be 10~15 portions of weight, jujubes be 8~12 parts by weight, the composition is in terms of kidney tonifying, essence replenishing, blood-nourishing dark hair
With extraordinary effect, especially when rhizoma polygonati is 11 parts by weight, mulberry fruit is 12 parts by weight, Semen sesami nigrum is 10 parts by weight, fructus lycii
When for 10 parts by weight, rose be 12 parts by weight, jujube is 10 parts by weight, better effect.In addition, the composition do not add it is auxiliary
Material is free of non-plant class raw material, natural and safety.
As the preferred embodiment of composition of the present invention, the composition contains rhizoma polygonati Ultramicro-powder, mulberries ultra micro
Powder, Semen sesami nigrum Ultramicro-powder, fructus lycii Ultramicro-powder, rose Ultramicro-powder and jujube Ultramicro-powder.Ultramicro-powder not only remains medicinal material
Full ingredient, and the cell wall of medicinal material is crushed during the preparation process, effective component separate out, so that the composition
Effective component can be directly used by the human body, improve drug effect.
The present invention also provides a kind of preparation methods of rhizoma polygonati jujube composition comprising following steps:
(1) rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube selection: are chosen;
(2) it pre-processes: the rhizoma polygonati of selection, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube is removed into impurity;
(3) medicinal material drying: deimpurity rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube will be gone dry to water
Divide≤6%, obtains dry material;
(4) allotment mixing: the material of the drying is uniformly mixed by following proportion: rhizoma polygonati is 10~15 parts by weight, mulberry
Mulberry is 10~15 parts by weight, and Semen sesami nigrum is 8~12 parts by weight, and fructus lycii is 8~12 parts by weight, and rose is 10~15 weight
Part, jujube is 8~12 parts by weight;
(5) it crushes: deployed material being first subjected to coarse crushing, obtains particle of the granularity less than 4 mesh, then granularity is less than
The particle of 4 mesh is pulverized, and the Ultramicro-powder that particle diameter distribution D90 is no more than 30 μm is obtained;
(6) it pelletizes, is dry: using water or edible alcohol as wetting agent, the Ultramicro-powder being subjected to wet granulation, is obtained soft
Softwood is successively crossed the twice sieve that mesh number is respectively A and B by material, and the softwood by granularity less than B pelletizes again, is sieved, by mesh number
Softwood drying to moisture within the scope of A~B is lower than 7.0%, is uniformly mixed later, obtains dry particle, the A < B;
(7) it sterilizes: sterilizing to dry particle;
(8) it dispenses: the particle of the drying after sterilizing is dispensed to get the composition.
As the preferred embodiment of preparation method of the present invention, rhizoma polygonati is 11 parts by weight, mulberry fruit in the step (4)
For 12 parts by weight, Semen sesami nigrum is 10 parts by weight, and fructus lycii is 10 parts by weight, and rose is 12 parts by weight, and jujube is 10 parts by weight.
As the preferred embodiment of preparation method of the present invention, the temperature pulverized in the step (5) is -25
~-10 DEG C.
As the preferred embodiment of preparation method of the present invention, drying temperature is 45 DEG C in the step (3);It is described
Drying temperature≤55 DEG C in step (6).
As the preferred embodiment of preparation method of the present invention, the A is 20 mesh, and the B is 40 mesh.
As the preferred embodiment of preparation method of the present invention, the dosage of water or edible alcohol in the step (6)
It is the 20~24% of Ultramicro-powder quality.
As the preferred embodiment of preparation method of the present invention, sterilized in the step (7) using vacuum microwave;Institute
It states in step (8) and the composition is packed using aluminium plastic bag.
Compared with prior art, the present invention has the following advantages and beneficial effects:
(1) rhizoma polygonati jujube composition of the present invention passes through rhizoma polygonati, mulberries, Semen sesami nigrum, fructus lycii, rose and jujube is scientific
Compatibility and have effects that excellent kidney tonifying, essence replenishing, blood-nourishing dark hair;Without auxiliary material, natural and safety.
(2) preparation method of rhizoma polygonati jujube composition of the present invention uses superfine communication technique, and substantially increasing medicinal material has
The dissolution rate for imitating ingredient, is beneficial to effective component and is directly used by the human body, and low-temperature operation can be used in whole production process, will not be to having
Effect ingredient damages.
(3) preparation method of rhizoma polygonati jujube composition of the present invention uses microwave sterilization and aluminium plastic bag packing technique, so that
The product prepared, which is not likely to produce, to go rancid, is rotten and other issues, and is conducive to product carrying, long-time storage and drinks peace
Entirely.
(4) preparation method of rhizoma polygonati jujube composition of the present invention is easy to operate, and condition is controllable, easy to industrialized production.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of embodiment of rhizoma polygonati jujube composition of the present invention, rhizoma polygonati jujube composition described in the present embodiment prepare raw material
As shown in table 1, preparation method includes the following steps:
(1) selection: detecting rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube, and selection meets " China
People's republic's pharmacopeia " rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube as defined in 2015 editions;
(2) it pre-processes: the rhizoma polygonati of selection, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube is removed into impurity;
(3) medicinal material drying: deimpurity rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube will be gone to be placed in 45 DEG C
Heat pump drying dehumidifier in be dried, obtain the dried material of moisture≤6.0%;
(4) allotment mixing: the material of the drying is uniformly mixed by following proportion: rhizoma polygonati is 10 parts by weight, and mulberry fruit is
10 parts by weight, Semen sesami nigrum are 8 parts by weight, and fructus lycii is 8 parts by weight, and rose is 10 parts by weight, and jujube is 8 parts by weight;
(5) it crushes: deployed material is successively carried out to coarse crushing and cross 4 mesh screens, then the particle by granularity less than 4 mesh
It puts micronizer into be crushed, temperature is set as -10 DEG C, is crushed to particle diameter distribution D90 no more than 30 μm, obtains ultra micro
Powder;
(6) it pelletizes, is dry: using the water that quality is Ultramicro-powder quality 24% as wetting agent, Ultramicro-powder being subjected to wet granulation,
Softwood is obtained, softwood is successively crossed into 20 mesh, 40 mesh screens, granularity is pelletized again less than the softwood of 40 mesh, is sieved, by 20~40
Purpose softwood, which is placed in 55 DEG C of heat pump drying dehumidifier, to be dried to moisture lower than 7.0%, is uniformly mixed later, is obtained drying
Particle;
(7) it sterilizes: being sterilized with microwave vacuum dryer to dry particle, reach the rear -0.04Mpa in vacuum degree
Microwave can be opened, sterilising temp is 70 DEG C, sterilization time 6min;
(8) it dispenses: the particle after sterilizing being packed to get the composition by 2 grams every bag using aluminium plastic bag.
Embodiment 2
A kind of embodiment of rhizoma polygonati jujube composition of the present invention, rhizoma polygonati jujube composition described in the present embodiment prepare raw material
As shown in table 1, preparation method includes the following steps:
(1) selection: detecting rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube, and selection meets " China
People's republic's pharmacopeia " rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube as defined in 2015 editions;
(2) it pre-processes: the rhizoma polygonati of selection, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube is removed into impurity;
(3) medicinal material drying: deimpurity rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube will be gone to be placed in 45 DEG C
Heat pump drying dehumidifier in be dried, obtain the dried material of moisture≤6.0%;
(4) allotment mixing: the material of the drying is uniformly mixed by following proportion: rhizoma polygonati is 11 parts by weight, mulberry fruit is
12 parts by weight, Semen sesami nigrum are 10 parts by weight, fructus lycii is 10 parts by weight, rose is 12 parts by weight, jujube is 10 parts by weight;
(5) it crushes: deployed material is successively carried out to coarse crushing and cross 4 mesh screens, then the particle by granularity less than 4 mesh
It puts micronizer into be crushed, temperature is set as -15 DEG C, is crushed to particle diameter distribution D90 no more than 30 μm, obtains ultra micro
Powder;
(6) it pelletizes, is dry: using the water that quality is Ultramicro-powder quality 22% as wetting agent, Ultramicro-powder being subjected to wet granulation,
Softwood is obtained, softwood is successively crossed into 20 mesh, 40 mesh screens, granularity is pelletized again less than the softwood of 40 mesh, is sieved, by 20~40
Purpose softwood, which is placed in 50 DEG C of heat pump drying dehumidifier, to be dried to moisture lower than 7.0%, is uniformly mixed later, is obtained drying
Particle;
(7) it sterilizes: being sterilized with microwave vacuum dryer to dry particle, reach the rear -0.04Mpa in vacuum degree
Microwave can be opened, sterilising temp is 70 DEG C, sterilization time 6min;
(8) it dispenses: the particle after sterilizing being packed to get the composition by 2 grams every bag using aluminium plastic bag.
Embodiment 3
A kind of embodiment of rhizoma polygonati jujube composition of the present invention, rhizoma polygonati jujube composition described in the present embodiment prepare raw material
As shown in table 1, preparation method includes the following steps:
(1) selection: detecting rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube, and selection meets " China
People's republic's pharmacopeia " rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube as defined in 2015 editions;
(2) it pre-processes: the rhizoma polygonati of selection, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube is removed into impurity;
(3) medicinal material drying: deimpurity rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube will be gone to be placed in 45 DEG C
Heat pump drying dehumidifier in be dried, obtain the dried material of moisture≤6.0%;
(4) allotment mixing: the material of the drying is uniformly mixed by following proportion: rhizoma polygonati is 15 parts by weight, and mulberry fruit is
15 parts by weight, Semen sesami nigrum are 12 parts by weight, and fructus lycii is 12 parts by weight, and rose is 15 parts by weight, and jujube is 12 parts by weight;
(5) it crushes: deployed material is successively carried out to coarse crushing and cross 4 mesh screens, then the particle by granularity less than 4 mesh
It puts micronizer into be crushed, temperature is set as -25 DEG C, is crushed to particle diameter distribution D90 no more than 30 μm, obtains ultra micro
Powder;
(6) it pelletizes, is dry: using the water that quality is Ultramicro-powder quality 20% as wetting agent, Ultramicro-powder being subjected to wet granulation,
Softwood is obtained, softwood is successively crossed into 20 mesh, 40 mesh screens, granularity is pelletized again less than the softwood of 40 mesh, is sieved, by 20~40
Purpose softwood, which is placed in 45 DEG C of heat pump drying dehumidifier, to be dried to moisture lower than 7.0%, is uniformly mixed later, is obtained drying
Particle;
(7) it sterilizes: being sterilized with microwave vacuum dryer to dry particle, reach the rear -0.04Mpa in vacuum degree
Microwave can be opened, sterilising temp is 70 DEG C, sterilization time 6min;
(8) it dispenses: the particle after sterilizing being packed to get the composition by 2 grams every bag using aluminium plastic bag.
Comparative example 1-8
Comparative example 1-8 is a kind of composition, prepares that raw material is as shown in table 1, and preparation method is the same as embodiment 2.
1 composition of table prepares composition/parts by weight of raw material
The effect of rhizoma polygonati jujube composition to illustrate the invention has carried out following test:
1, kidney tonifying, essence replenishing efficacy test
(1) test method
110 kidney deficiency male patients making a definite diagnosis are selected, are divided into 11 groups at random, every group is taken a kind of composition, and daily 3
Secondary, one time one packet, half an hour takes after the meal every time, and each group is counted after taking 30 days, 30 days and takes effect.
(2) effect judgment criteria
Effect is divided into 3 grades, (1) is effective: in high spirits, energetic, sexuality is powerful;(2) spirit collection
In, not easy to fatigue, sexual function restores;(3) invalid: energy is not good, fatigability function lowers.
(3) test result
Test concrete outcome is shown in Table 2.
Effect after 2 edible composition of table
2, dark hair efficacy test
30 serious patients of 35~50 years old white hair are chosen, adhere to taking rhizoma polygonati jujube composition 30 as described in example 2
It, 3 times a day, one time one packet, half an hour takes after the meal every time, has example to have apparent improvement after 30 days, and effective percentage reaches
56%.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of rhizoma polygonati jujube composition, it is characterised in that: the composition prepares the ingredient that raw material includes following parts by weight:
10~15 parts of rhizoma polygonati, 10~15 parts of mulberry fruit, 8~12 parts of Semen sesami nigrum, 8~12 parts of fructus lycii, 10~15 parts of rose, jujube 8~
12 parts.
2. composition according to claim 1, it is characterised in that: the raw material for preparing of the composition includes following parts by weight
Ingredient: 11 parts of rhizoma polygonati, 12 parts of mulberry fruit, 10 parts of Semen sesami nigrum, 10 parts of fructus lycii, 12 parts of rose, 10 parts of jujube.
3. composition according to claim 1 or 2, it is characterised in that: it is super that the composition contains rhizoma polygonati Ultramicro-powder, mulberries
Micro mist, Semen sesami nigrum Ultramicro-powder, fructus lycii Ultramicro-powder, rose Ultramicro-powder and jujube Ultramicro-powder.
4. a kind of preparation method of rhizoma polygonati jujube composition, it is characterised in that: the preparation method comprises the following steps:
(1) rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube selection: are chosen;
(2) it pre-processes: the rhizoma polygonati of selection, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube is removed into impurity;
(3) medicinal material drying: deimpurity rhizoma polygonati, mulberry fruit, Semen sesami nigrum, fructus lycii, rose and jujube will be gone dry to moisture≤
6%, obtain dry material;
(4) allotment mixing: the material of the drying is uniformly mixed by following proportion: rhizoma polygonati is 10~15 parts by weight, and mulberry fruit is
10~15 parts by weight, Semen sesami nigrum are 8~12 parts by weight, and fructus lycii is 8~12 parts by weight, and rose is 10~15 parts by weight, greatly
Jujube is 8~12 parts by weight;
(5) it crushes: deployed material being first subjected to coarse crushing, obtains particle of the granularity less than 4 mesh, then by granularity less than 4 mesh
Particle pulverized, obtain particle diameter distribution D90 and be no more than 30 μm of Ultramicro-powder;
(6) it pelletizes, is dry: using water or edible alcohol as wetting agent, the Ultramicro-powder being subjected to wet granulation, obtains softwood, it will
Softwood successively crosses the twice sieve that mesh number is respectively A and B, and the softwood by granularity less than B pelletizes again, is sieved, by mesh number A~
Softwood drying to moisture within the scope of B is lower than 7.0%, is uniformly mixed later, obtains dry particle, the A < B;
(7) it sterilizes: sterilizing to dry particle;
(8) it dispenses: the particle of the drying after sterilizing is dispensed to get the composition.
5. the preparation method according to claim 4, it is characterised in that: rhizoma polygonati is 11 parts by weight, mulberry fruit in the step (4)
For 12 parts by weight, Semen sesami nigrum is 10 parts by weight, and fructus lycii is 10 parts by weight, and rose is 12 parts by weight, and jujube is 10 parts by weight.
6. preparation method according to claim 4 or 5, it is characterised in that: the temperature pulverized in the step (5)
It is -25~-10 DEG C.
7. preparation method according to claim 4 or 5, it is characterised in that: drying temperature is 45 DEG C in the step (3);
Drying temperature≤55 DEG C in the step (6).
8. preparation method according to claim 4 or 5, it is characterised in that: the A is 20 mesh, and the B is 40 mesh.
9. preparation method according to claim 4 or 5, it is characterised in that: the use of water or edible alcohol in the step (6)
Amount is the 20~24% of Ultramicro-powder quality.
10. preparation method according to claim 4 or 5, it is characterised in that: gone out in the step (7) using vacuum microwave
Bacterium;The composition is packed using aluminium plastic bag in the step (8).
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