CN103923192A - 用于富集、分离和检测循环肿瘤细胞的多肽及其应用 - Google Patents
用于富集、分离和检测循环肿瘤细胞的多肽及其应用 Download PDFInfo
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- CN103923192A CN103923192A CN201310013908.1A CN201310013908A CN103923192A CN 103923192 A CN103923192 A CN 103923192A CN 201310013908 A CN201310013908 A CN 201310013908A CN 103923192 A CN103923192 A CN 103923192A
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- C07—ORGANIC CHEMISTRY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104483300A (zh) * | 2014-12-18 | 2015-04-01 | 苏州大学 | 一种检测循环肿瘤细胞的装置 |
CN104535772A (zh) * | 2014-12-22 | 2015-04-22 | 国家纳米科学中心 | Her2高表达的循环肿瘤细胞的多肽-磁性纳米颗粒及其制备方法和应用 |
CN105440112A (zh) * | 2015-12-07 | 2016-03-30 | 国家纳米科学中心 | 多肽-白蛋白偶联药物、其制备方法及应用 |
CN109112107A (zh) * | 2018-09-11 | 2019-01-01 | 上海浦美医学科技有限公司 | 一种基于rgd多肽捕获分离ctc的方法 |
CN110501208A (zh) * | 2018-05-17 | 2019-11-26 | 国家纳米科学中心 | 叶酸功能化的链霉亲和素修饰的磁性纳米颗粒、其制备方法和应用 |
CN110579605A (zh) * | 2019-08-13 | 2019-12-17 | 姜宇腾 | 一种快速分离免疫磁珠的方法 |
CN111632202A (zh) * | 2020-06-29 | 2020-09-08 | 南开大学 | 肿瘤细胞粘附材料及其制备方法和应用 |
CN111983220A (zh) * | 2019-05-21 | 2020-11-24 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
CN112410302A (zh) * | 2020-11-10 | 2021-02-26 | 福建医科大学 | 基于多靶标组合的肿瘤干细胞的富集和筛选方法 |
WO2021102919A1 (zh) * | 2019-11-29 | 2021-06-03 | 京东方科技集团股份有限公司 | 类肽化合物以及表面偶联有类肽化合物的检测芯片 |
CN115404220A (zh) * | 2021-05-27 | 2022-11-29 | 中国科学院化学研究所 | 一种分离富集循环肿瘤细胞的多肽功能化微纳界面材料及其制备方法和应用 |
CN116884506A (zh) * | 2023-09-06 | 2023-10-13 | 北京科技大学 | 不同温度下载药纳米颗粒在血管壁富集的预测方法及*** |
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CN102527353A (zh) * | 2011-12-21 | 2012-07-04 | 深圳市老年医学研究所 | 一种用于富集循环肿瘤细胞的纳米磁性免疫微球制备 |
CN102586189A (zh) * | 2012-02-02 | 2012-07-18 | 厦门艾德生物医药科技有限公司 | 一种循环肿瘤细胞特异性富集方法 |
CN102830228A (zh) * | 2011-06-15 | 2012-12-19 | 妙华思博生物科技(上海)有限公司 | 定量分析循环肿瘤细胞的试剂及试剂盒 |
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- 2013-01-15 CN CN201310013908.1A patent/CN103923192B/zh active Active
Patent Citations (3)
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CN102830228A (zh) * | 2011-06-15 | 2012-12-19 | 妙华思博生物科技(上海)有限公司 | 定量分析循环肿瘤细胞的试剂及试剂盒 |
CN102527353A (zh) * | 2011-12-21 | 2012-07-04 | 深圳市老年医学研究所 | 一种用于富集循环肿瘤细胞的纳米磁性免疫微球制备 |
CN102586189A (zh) * | 2012-02-02 | 2012-07-18 | 厦门艾德生物医药科技有限公司 | 一种循环肿瘤细胞特异性富集方法 |
Non-Patent Citations (3)
Title |
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AGGARWAL S.等: "A combinatorial approach to the selective capture of circulating malignant epithelial cells by peptide ligands", 《BIOMATERIALS》 * |
BAI L-L.等: "Peptide-based isolation of circulating tumor cells by magnetic nanoparticles", 《JOURNAL OF MATERIALS CHEMISTRY B》 * |
XU H-Y.等: "Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood", 《BIOMATERIALS》 * |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104483300A (zh) * | 2014-12-18 | 2015-04-01 | 苏州大学 | 一种检测循环肿瘤细胞的装置 |
CN104483300B (zh) * | 2014-12-18 | 2017-06-13 | 苏州大学 | 一种检测循环肿瘤细胞的装置 |
CN104535772A (zh) * | 2014-12-22 | 2015-04-22 | 国家纳米科学中心 | Her2高表达的循环肿瘤细胞的多肽-磁性纳米颗粒及其制备方法和应用 |
CN105440112A (zh) * | 2015-12-07 | 2016-03-30 | 国家纳米科学中心 | 多肽-白蛋白偶联药物、其制备方法及应用 |
CN110501208A (zh) * | 2018-05-17 | 2019-11-26 | 国家纳米科学中心 | 叶酸功能化的链霉亲和素修饰的磁性纳米颗粒、其制备方法和应用 |
CN110501208B (zh) * | 2018-05-17 | 2023-06-27 | 国家纳米科学中心 | 叶酸功能化的链霉亲和素修饰的磁性纳米颗粒、其制备方法和应用 |
CN109112107A (zh) * | 2018-09-11 | 2019-01-01 | 上海浦美医学科技有限公司 | 一种基于rgd多肽捕获分离ctc的方法 |
CN111983220A (zh) * | 2019-05-21 | 2020-11-24 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
WO2020233572A1 (zh) * | 2019-05-21 | 2020-11-26 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
CN113826013A (zh) * | 2019-05-21 | 2021-12-21 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
CN111983220B (zh) * | 2019-05-21 | 2024-03-19 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
CN113826013B (zh) * | 2019-05-21 | 2024-05-24 | 北京中科纳泰生物科技有限公司 | 多肽磁性纳米颗粒、其制备方法及应用 |
CN110579605A (zh) * | 2019-08-13 | 2019-12-17 | 姜宇腾 | 一种快速分离免疫磁珠的方法 |
WO2021102919A1 (zh) * | 2019-11-29 | 2021-06-03 | 京东方科技集团股份有限公司 | 类肽化合物以及表面偶联有类肽化合物的检测芯片 |
CN111632202A (zh) * | 2020-06-29 | 2020-09-08 | 南开大学 | 肿瘤细胞粘附材料及其制备方法和应用 |
CN112410302A (zh) * | 2020-11-10 | 2021-02-26 | 福建医科大学 | 基于多靶标组合的肿瘤干细胞的富集和筛选方法 |
CN115404220A (zh) * | 2021-05-27 | 2022-11-29 | 中国科学院化学研究所 | 一种分离富集循环肿瘤细胞的多肽功能化微纳界面材料及其制备方法和应用 |
CN116884506A (zh) * | 2023-09-06 | 2023-10-13 | 北京科技大学 | 不同温度下载药纳米颗粒在血管壁富集的预测方法及*** |
CN116884506B (zh) * | 2023-09-06 | 2023-11-17 | 北京科技大学 | 不同温度下载药纳米颗粒在血管壁富集的预测方法及*** |
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Application publication date: 20140716 Assignee: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY(NCNST) OF CHINA Assignor: Beijing Kenatai Technology Co. Ltd. Contract record no.: 2016990000325 Denomination of invention: Polypeptide for enrichment, separation and detection of circulating tumor cells and application thereof Granted publication date: 20160316 License type: Common License Record date: 20160812 |
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Application publication date: 20140716 Assignee: Tianjin Zhongke biological science and Technology Co Ltd Assignor: Beijing Kenatai Technology Co. Ltd. Contract record no.: 2016990000328 Denomination of invention: Polypeptide for enrichment, separation and detection of circulating tumor cells and application thereof Granted publication date: 20160316 License type: Common License Record date: 20160823 |
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