CN103735850A - Medicament for treating dentin hypersensitivity - Google Patents
Medicament for treating dentin hypersensitivity Download PDFInfo
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- CN103735850A CN103735850A CN201410034958.2A CN201410034958A CN103735850A CN 103735850 A CN103735850 A CN 103735850A CN 201410034958 A CN201410034958 A CN 201410034958A CN 103735850 A CN103735850 A CN 103735850A
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Abstract
The invention relates to a medicament for treating dentin hypersensitivity. The medicament is prepared from the following raw materials in parts by weight: 12 parts of leucosceptrum canum, 12 parts of a serpent medicine, 12 parts of large black powder, 11 parts of notholirion bulbuliferum, 9 parts of common nepenthes, 9 parts of callicarpa longifolia, 9 parts of orchis, 9 parts of cattle long grass, 9 parts of herb of common elsholtzia, 6 parts of auricled hedyotis herb, 6 parts of astilbe chinensis, 5 parts of crowtoe, 5 parts of crowtoe, 3 parts of water-dragon, 3 parts of hypericum patulum, 3 parts of nodding clinacanthus, 2 parts of lemmaphyllum microphyllum and 2 parts of large-leaved chrysosplenium. The medicament for treating the dentin hypersensitivity, disclosed by the invention, is reasonable in formula, has a definite effect and can effectively treat the dentin hypersensitivity.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of dentin hypersensitiveness.
Background technology
Dental hypersensitiveness refers to when the dentin exposing on tooth is partly subject to machinery, chemistry or thermal stimulus, produces the symptom of a kind of special acid, " soft ", pain.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of dentin hypersensitiveness.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of dentin hypersensitiveness, it is to be made by weight by following bulk drugs: meter Tuan Hua 10-20 part, Radix seu Cortex Heteropanacis Fragrantis 10-20 part, Radix Inulae Pterocaulae 10-20 part, Bullus Notholirionis Bulbuliferi 10-20 part, Herba nepenthis 1-10 part, cow tongue Huang 1-10 part, Herba Orchidis Latifoliae 1-10 part, Herba Circaeae Cordatae 1-10 part, Herba Elsholtziae Ciliatae 1-10 part, Auricled Hedyotis Herb 1-10 part, Herba astilbes chinensis 1-10 part, Radix Loti Corniculati 1-10 part, Radix Loti Corniculati 1-10 part, Herba Jussiaeae Repentis 1-5 part, Herba Hyperici Patuli 1-5 part, Herba Clinacanthi Nutantis 1-5 part, Drymoglossum Herba Drymoglossi 1-5 part and Herba Chrysosplenii Macrophylli 1-5 part.
Preferably, the medicament for the treatment of of the present invention dentin hypersensitiveness is to be made by weight by following bulk drugs: 2 parts of 12 parts of meter Tuan Hua, 12 parts of Radix seu Cortex Heteropanacis Fragrantiss, 12 parts of Radix Inulae Pterocaulaes, 11 parts of Bullus Notholirionis Bulbuliferi, 9 parts of Herba nepenthiss, 9 parts of cow tongue Huang, 9 parts of Herba Orchidis Latifoliae, 9 parts of Herba Circaeae Cordatae, 9 parts of Herba Elsholtziae Ciliataes, 6 parts of Auricled Hedyotis Herbs, 6 parts of Herba astilbes chinensiss, 5 parts of Radix Loti Corniculatis, 5 parts of Radix Loti Corniculatis, 3 parts of Herba Jussiaeae Repentiss, 3 parts of Herba Hyperici Patulis, 3 parts of Herba Clinacanthi Nutantis, 2 parts of Drymoglossum Herba Drymoglossis and Herba Chrysosplenii Macrophyllis.
More preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or collutory.
In compositions of the present invention, meter Tuan Hua, Radix seu Cortex Heteropanacis Fragrantis, Radix Inulae Pterocaulae, Bullus Notholirionis Bulbuliferi are monarch drug; Herba nepenthis, cow tongue Huang, Herba Orchidis Latifoliae, Herba Circaeae Cordatae, Herba Elsholtziae Ciliatae are ministerial drug; Auricled Hedyotis Herb, Herba astilbes chinensis, Radix Loti Corniculati, Radix Loti Corniculati are adjuvant drug; Herba Jussiaeae Repentis, Herba Hyperici Patuli, Herba Clinacanthi Nutantis, Drymoglossum Herba Drymoglossi and Herba Chrysosplenii Macrophylli are for making medicine, and various composition performance synergism are to produce optimum efficiency.
In order to understand better the present invention, with reference to < < Chinese medicine voluminous dictionary > > second edition (Shanghai science tech publishing house, 2005) explanation of some crude drug that, use in the present invention sees the following form:
The drug prescription for the treatment of of the present invention dentin hypersensitiveness is reasonable, and effect is clear and definite, can effectively treat dentin hypersensitiveness.
The specific embodiment
Below by embodiment, further illustrate the present invention.It should be understood that embodiments of the invention are for the present invention rather than limitation of the present invention are described.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the scope of protection of present invention.Except as otherwise noted, the percent otherwise in the present invention is percetage by weight.
Embodiment collutory of the present invention
Get 2 grams of 12 grams of meter Tuan Hua, 12 grams of Radix seu Cortex Heteropanacis Fragrantiss, 12 grams of Radix Inulae Pterocaulaes, 11 grams of Bullus Notholirionis Bulbuliferi, 9 grams of Herba nepenthiss, 9 grams of cow tongue Huang, 9 grams of Herba Orchidis Latifoliae, 9 grams of Herba Circaeae Cordatae, 9 grams of Herba Elsholtziae Ciliataes, 6 grams of Auricled Hedyotis Herbs, 6 grams of Herba astilbes chinensiss, 5 grams of Radix Loti Corniculatis, 5 grams of Radix Loti Corniculatis, 3 grams of Herba Jussiaeae Repentiss, 3 grams of Herba Hyperici Patulis, 3 grams of Herba Clinacanthi Nutantis, 2 grams of Drymoglossum Herba Drymoglossis and Herba Chrysosplenii Macrophyllis, add 20000 milliliters, water, in being housed, at 100 ℃, heats 5 hours by the flask of condenser, filter, filtrate is collutory of the present invention.
Experimental example
Physical data
Choose in December, 2012 to 2013 patient's 40 examples that year November, accepted for medical treatment the court, totally 124 teeth.Man's 20 examples, 76 teeth; Female's 20 examples, 48 teeth.Age 22-66 year, 41 years old mean age.In one month, do not make any desensitization treatment, cold stimulation is positive, and probe slides and feels aching and limp person, and tooth closes face irregular wear or severe dental attrition.Trouble tooth is divided into 2 groups, 62 of matched groups, 62 for the treatment of groups, the physical data comparison such as two groups of patient ages, sex ratio and coincident with severity degree of conditions, classification, difference not statistically significant (P>0.05), has comparability.
Treatment group is treated with the collutory of preparation in embodiment 1, uses 50ml to gargle 1 minute at every turn.Every day 3 times.Using continuously 1 week is 1 course for the treatment of.
Matched group is used 75 % by weight sodium fluoride glycerine paste desensitizations: clean dry facing, and with cotton pellet, dip in 75 % by weight sodium fluoride glycerine pastes and repeatedly embrocate 1-2min at sensitivity place, once a day, using continuously 1 week is 1 course for the treatment of.
Efficacy assessment standard
Effective: after treatment, subjective symptoms disappears, caloric stimulation, spy are examined all without uncomfortable.Effective: after treatment, subjective symptoms takes a turn for the better, caloric stimulation, spy are examined slightly uncomfortable.Invalid: treatment front and back are without significant change.
Result
Through treatment, the therapeutic outcome of two groups sees the following form:
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 62 | 42 | 18 | 2 | 96.7 |
| Matched group | 62 | 25 | 27 | 10 | 83.8 |
Claims (3)
1. a medicament for the treatment of dentin hypersensitiveness, it is characterized in that, it is to be made by weight by following bulk drugs: meter Tuan Hua 10-20 part, Radix seu Cortex Heteropanacis Fragrantis 10-20 part, Radix Inulae Pterocaulae 10-20 part, Bullus Notholirionis Bulbuliferi 10-20 part, Herba nepenthis 1-10 part, cow tongue Huang 1-10 part, Herba Orchidis Latifoliae 1-10 part, Herba Circaeae Cordatae 1-10 part, Herba Elsholtziae Ciliatae 1-10 part, Auricled Hedyotis Herb 1-10 part, Herba astilbes chinensis 1-10 part, Radix Loti Corniculati 1-10 part, Radix Loti Corniculati 1-10 part, Herba Jussiaeae Repentis 1-5 part, Herba Hyperici Patuli 1-5 part, Herba Clinacanthi Nutantis 1-5 part, Drymoglossum Herba Drymoglossi 1-5 part and Herba Chrysosplenii Macrophylli 1-5 part.
2. the medicament for the treatment of according to claim 1 dentin hypersensitiveness, it is characterized in that, it is to be made by weight by following bulk drugs: 2 parts of 12 parts of meter Tuan Hua, 12 parts of Radix seu Cortex Heteropanacis Fragrantiss, 12 parts of Radix Inulae Pterocaulaes, 11 parts of Bullus Notholirionis Bulbuliferi, 9 parts of Herba nepenthiss, 9 parts of cow tongue Huang, 9 parts of Herba Orchidis Latifoliae, 9 parts of Herba Circaeae Cordatae, 9 parts of Herba Elsholtziae Ciliataes, 6 parts of Auricled Hedyotis Herbs, 6 parts of Herba astilbes chinensiss, 5 parts of Radix Loti Corniculatis, 5 parts of Radix Loti Corniculatis, 3 parts of Herba Jussiaeae Repentiss, 3 parts of Herba Hyperici Patulis, 3 parts of Herba Clinacanthi Nutantis, 2 parts of Drymoglossum Herba Drymoglossis and Herba Chrysosplenii Macrophyllis.
3. according to the medicament of the treatment dentin hypersensitiveness described in claim 1 or 2, it is characterized in that, described medicament can be tablet, dispersible tablet, disintegrating tablet, instant, enteric coatel tablets, capsule or collutory.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410034958.2A CN103735850B (en) | 2014-01-24 | 2014-01-24 | A kind of medicament for the treatment of dentin hypersensitiveness |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410034958.2A CN103735850B (en) | 2014-01-24 | 2014-01-24 | A kind of medicament for the treatment of dentin hypersensitiveness |
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| Publication Number | Publication Date |
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| CN103735850A true CN103735850A (en) | 2014-04-23 |
| CN103735850B CN103735850B (en) | 2015-11-25 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147307A (en) * | 2014-08-11 | 2014-11-19 | 张柯 | Pharmaceutical composition for treatment of dentin hypersensitivity of false tooth patients |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070971A (en) * | 2013-02-28 | 2013-05-01 | 吕忠绪 | Traditional Chinese medicament composition for treating hemodia, odontoseisis and toothache |
| CN103263540A (en) * | 2013-05-28 | 2013-08-28 | 阮福求 | Tooth brushing medicinal liquid for preventing and treating odontopathy |
-
2014
- 2014-01-24 CN CN201410034958.2A patent/CN103735850B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070971A (en) * | 2013-02-28 | 2013-05-01 | 吕忠绪 | Traditional Chinese medicament composition for treating hemodia, odontoseisis and toothache |
| CN103263540A (en) * | 2013-05-28 | 2013-08-28 | 阮福求 | Tooth brushing medicinal liquid for preventing and treating odontopathy |
Non-Patent Citations (2)
| Title |
|---|
| 刘伟: "中药治疗牙本质过敏的临床观察", 《宁夏医科大学学报》 * |
| 刘庆生 等: "中药脱敏剂用于治疗牙本质过敏症的临床疗效", 《中国实用医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147307A (en) * | 2014-08-11 | 2014-11-19 | 张柯 | Pharmaceutical composition for treatment of dentin hypersensitivity of false tooth patients |
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| Publication number | Publication date |
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| CN103735850B (en) | 2015-11-25 |
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Granted publication date: 20151125 Termination date: 20170124 |