CN103735850B - A kind of medicament for the treatment of dentin hypersensitiveness - Google Patents
A kind of medicament for the treatment of dentin hypersensitiveness Download PDFInfo
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- CN103735850B CN103735850B CN201410034958.2A CN201410034958A CN103735850B CN 103735850 B CN103735850 B CN 103735850B CN 201410034958 A CN201410034958 A CN 201410034958A CN 103735850 B CN103735850 B CN 103735850B
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Abstract
The present invention relates to a kind of medicament for the treatment of dentin hypersensitiveness, it is made up by weight of following bulk drugs: meter Tuan Hua 12 parts, Radix seu Cortex Heteropanacis Fragrantis 12 parts, Radix Inulae Pterocaulae 12 parts, Bullus Notholirionis Bulbuliferi 11 parts, Herba nepenthis 9 parts, cow tongue Huang 9 parts, Herba Orchidis Latifoliae 9 parts, Herba Circaeae Cordatae 9 parts, Herba Elsholtziae Ciliatae 9 parts, Auricled Hedyotis Herb 6 parts, Herba astilbes chinensis 6 parts, Radix Loti Corniculati 5 parts, Radix Loti Corniculati 5 parts, Herba Jussiaeae Repentis 3 parts, Herba Hyperici Patuli 3 parts, Herba Clinacanthi Nutantis 3 parts, Drymoglossum Herba Drymoglossi 2 parts and Herba Chrysosplenii Macrophylli 2 parts.The drug prescription for the treatment of dentin hypersensitiveness of the present invention is reasonable, and definite effect, effectively can treat dentin hypersensitiveness.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament for the treatment of dentin hypersensitiveness.
Background technology
When dental hypersensitiveness refers to that the dentin part that tooth exposes is subject to machinery, chemistry or thermal stimulus, produce the symptom of a kind of special acid, " soft ", pain.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of dentin hypersensitiveness.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of dentin hypersensitiveness, it is made up by weight of following bulk drugs: meter Tuan Hua 10-20 part, Radix seu Cortex Heteropanacis Fragrantis 10-20 part, Radix Inulae Pterocaulae 10-20 part, Bullus Notholirionis Bulbuliferi 10-20 part, Herba nepenthis 1-10 part, cow tongue Huang 1-10 part, Herba Orchidis Latifoliae 1-10 part, Herba Circaeae Cordatae 1-10 part, Herba Elsholtziae Ciliatae 1-10 part, Auricled Hedyotis Herb 1-10 part, Herba astilbes chinensis 1-10 part, Radix Loti Corniculati 1-10 part, Radix Loti Corniculati 1-10 part, Herba Jussiaeae Repentis 1-5 part, Herba Hyperici Patuli 1-5 part, Herba Clinacanthi Nutantis 1-5 part, Drymoglossum Herba Drymoglossi 1-5 part and Herba Chrysosplenii Macrophylli 1-5 part.
Preferably, the medicament for the treatment of dentin hypersensitiveness of the present invention is made up by weight of following bulk drugs: meter Tuan Hua 12 parts, Radix seu Cortex Heteropanacis Fragrantis 12 parts, Radix Inulae Pterocaulae 12 parts, Bullus Notholirionis Bulbuliferi 11 parts, Herba nepenthis 9 parts, cow tongue Huang 9 parts, Herba Orchidis Latifoliae 9 parts, Herba Circaeae Cordatae 9 parts, Herba Elsholtziae Ciliatae 9 parts, Auricled Hedyotis Herb 6 parts, Herba astilbes chinensis 6 parts, Radix Loti Corniculati 5 parts, Radix Loti Corniculati 5 parts, Herba Jussiaeae Repentis 3 parts, Herba Hyperici Patuli 3 parts, Herba Clinacanthi Nutantis 3 parts, Drymoglossum Herba Drymoglossi 2 parts and Herba Chrysosplenii Macrophylli 2 parts.
More preferably, described medicament can be tablet, dispersible tablet, disintegrating tablet, rapidly dissolving tablet, enteric coatel tablets, capsule or collutory.
In the present compositions, meter Tuan Hua, Radix seu Cortex Heteropanacis Fragrantis, Radix Inulae Pterocaulae, Bullus Notholirionis Bulbuliferi are monarch drug; Herba nepenthis, cow tongue Huang, Herba Orchidis Latifoliae, Herba Circaeae Cordatae, Herba Elsholtziae Ciliatae are ministerial drug; Auricled Hedyotis Herb, Herba astilbes chinensis, Radix Loti Corniculati, Radix Loti Corniculati are adjuvant drug; Herba Jussiaeae Repentis, Herba Hyperici Patuli, Herba Clinacanthi Nutantis, Drymoglossum Herba Drymoglossi and Herba Chrysosplenii Macrophylli are for making medicine, and various ingredient exerts synergism is to produce optimum efficiency.
In order to understand the present invention better, with reference to " Chinese medicine voluminous dictionary " second edition (Shanghai science tech publishing house, 2005), the explanation of some crude drug used in the present invention sees the following form:
The drug prescription for the treatment of dentin hypersensitiveness of the present invention is reasonable, and definite effect, effectively can treat dentin hypersensitiveness.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment collutory of the present invention
Get meter Tuan Hua 12 grams, Radix seu Cortex Heteropanacis Fragrantis 12 grams, Radix Inulae Pterocaulae 12 grams, Bullus Notholirionis Bulbuliferi 11 grams, Herba nepenthis 9 grams, cow tongue Huang 9 grams, Herba Orchidis Latifoliae 9 grams, Herba Circaeae Cordatae 9 grams, Herba Elsholtziae Ciliatae 9 grams, Auricled Hedyotis Herb 6 grams, Herba astilbes chinensis 6 grams, Radix Loti Corniculati 5 grams, Radix Loti Corniculati 5 grams, Herba Jussiaeae Repentis 3 grams, Herba Hyperici Patuli 3 grams, Herba Clinacanthi Nutantis 3 grams, Drymoglossum Herba Drymoglossi 2 grams and Herba Chrysosplenii Macrophylli 2 grams, add 20000 milliliters, water, heat 5 hours at 100 DEG C in the flask that condenser is housed, filter, filtrate is collutory of the present invention.
Experimental example
Physical data
Choose in December, 2012 to 2013 patient 40 example that year November, the court accepted for medical treatment, totally 124 teeth.Man 20 example, 76 teeth; Female 20 example, 48 teeth.Age 22-66 year, 41 years old mean age.In one month, do not make any desensitization treatment, cold stimulation is positive, and probe slides and feels aching and limp person, and tooth closes face irregular wear or severe dental attrition.Trouble tooth is divided into 2 groups, matched group 62, treatment group 62, two groups of patient ages, sex ratio and physical data such as coincident with severity degree of condition, classification compare, and no significant difference (P>0.05), has comparability.
Treatment group uses the collutory of preparation in embodiment 1 to treat, and each 50ml that uses carries out gargling 1 minute.Every day 3 times.Continuous use 1 week is 1 course for the treatment of.
Matched group uses 75 % by weight sodium fluoride glycerine paste desensitizations: clean dry facing, dips in 75 % by weight sodium fluoride glycerine pastes repeatedly embrocate 1-2min at sensitivity place with cotton pellet, and once a day, using continuously 1 week is 1 course for the treatment of.
Efficacy assessment standard
Effective: after treatment, subjective symptoms disappears, caloric stimulation, spy are examined all without uncomfortable.Effective: after treatment, subjective symptoms takes a turn for the better, caloric stimulation, spy are examined slightly uncomfortable.Invalid: without significant change before and after treatment.
Result
Through treatment, the therapeutic outcome of two groups sees the following form:
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 62 | 42 | 18 | 2 | 96.7 |
| Matched group | 62 | 25 | 27 | 10 | 83.8 |
Claims (2)
1. treat the medicament of dentin hypersensitiveness for one kind, it is characterized in that, it is made up by weight of following bulk drugs: meter Tuan Hua 10-20 part, Radix seu Cortex Heteropanacis Fragrantis 10-20 part, Radix Inulae Pterocaulae 10-20 part, Bullus Notholirionis Bulbuliferi 10-20 part, Herba nepenthis 1-10 part, cow tongue Huang 1-10 part, Herba Orchidis Latifoliae 1-10 part, Herba Circaeae Cordatae 1-10 part, Herba Elsholtziae Ciliatae 1-10 part, Auricled Hedyotis Herb 1-10 part, Herba astilbes chinensis 1-10 part, Radix Loti Corniculati 1-10 part, Radix Loti Corniculati 1-10 part, Herba Jussiaeae Repentis 1-5 part, Herba Hyperici Patuli 1-5 part, Herba Clinacanthi Nutantis 1-5 part, Drymoglossum Herba Drymoglossi 1-5 part and Herba Chrysosplenii Macrophylli 1-5 part.
2. the medicament for the treatment of dentin hypersensitiveness according to claim 1, it is characterized in that, it is made up by weight of following bulk drugs: meter Tuan Hua 12 parts, Radix seu Cortex Heteropanacis Fragrantis 12 parts, Radix Inulae Pterocaulae 12 parts, Bullus Notholirionis Bulbuliferi 11 parts, Herba nepenthis 9 parts, cow tongue Huang 9 parts, Herba Orchidis Latifoliae 9 parts, Herba Circaeae Cordatae 9 parts, Herba Elsholtziae Ciliatae 9 parts, Auricled Hedyotis Herb 6 parts, Herba astilbes chinensis 6 parts, Radix Loti Corniculati 5 parts, Radix Loti Corniculati 5 parts, Herba Jussiaeae Repentis 3 parts, Herba Hyperici Patuli 3 parts, Herba Clinacanthi Nutantis 3 parts, Drymoglossum Herba Drymoglossi 2 parts and Herba Chrysosplenii Macrophylli 2 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410034958.2A CN103735850B (en) | 2014-01-24 | 2014-01-24 | A kind of medicament for the treatment of dentin hypersensitiveness |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410034958.2A CN103735850B (en) | 2014-01-24 | 2014-01-24 | A kind of medicament for the treatment of dentin hypersensitiveness |
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| Publication Number | Publication Date |
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| CN103735850A CN103735850A (en) | 2014-04-23 |
| CN103735850B true CN103735850B (en) | 2015-11-25 |
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| CN201410034958.2A Expired - Fee Related CN103735850B (en) | 2014-01-24 | 2014-01-24 | A kind of medicament for the treatment of dentin hypersensitiveness |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147307A (en) * | 2014-08-11 | 2014-11-19 | 张柯 | Pharmaceutical composition for treatment of dentin hypersensitivity of false tooth patients |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070971A (en) * | 2013-02-28 | 2013-05-01 | 吕忠绪 | Traditional Chinese medicament composition for treating hemodia, odontoseisis and toothache |
| CN103263540A (en) * | 2013-05-28 | 2013-08-28 | 阮福求 | Tooth brushing medicinal liquid for preventing and treating odontopathy |
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2014
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103070971A (en) * | 2013-02-28 | 2013-05-01 | 吕忠绪 | Traditional Chinese medicament composition for treating hemodia, odontoseisis and toothache |
| CN103263540A (en) * | 2013-05-28 | 2013-08-28 | 阮福求 | Tooth brushing medicinal liquid for preventing and treating odontopathy |
Non-Patent Citations (2)
| Title |
|---|
| 中药治疗牙本质过敏的临床观察;刘伟;《宁夏医科大学学报》;20120131;第34卷(第1期);第90-91页 * |
| 中药脱敏剂用于治疗牙本质过敏症的临床疗效;刘庆生 等;《中国实用医药》;20130630;第8卷(第17期);第159-160页 * |
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