CN104306649B - A kind of medicament for the treatment of herpes zoster - Google Patents

A kind of medicament for the treatment of herpes zoster Download PDF

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Publication number
CN104306649B
CN104306649B CN201410598374.8A CN201410598374A CN104306649B CN 104306649 B CN104306649 B CN 104306649B CN 201410598374 A CN201410598374 A CN 201410598374A CN 104306649 B CN104306649 B CN 104306649B
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parts
herba
medicament
herpes zoster
treatment
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CN104306649A (en
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薛红
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Xue Hong
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/09Lichens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus

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  • Health & Medical Sciences (AREA)
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Abstract

The present invention relates to a kind of medicament for the treatment of herpes zoster, it is made up of the material of following weight proportioning: Herba Aletridis Khasianae, Cortex schizophragmatis integrifolii radicis, Radix Codonopsis lanceolatae, Radix Fici comatae, Flos Mume, Cissus pteroclada Hayata, Ilex purpurea Hassk.[I.chinensis Sims, Ramulus et Folium Bischofiae Javanicae, Parmelia tinctorum Despr., Herba hyperici attenuati, Herba Reineckeae Carneae, sanicle, Herba Lespedezae Cuneatae, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke, Cortex Xylosmae japonici, Rhizoma disporopsis pernyi, Lombardy poplar, clothing of failing, Caulis et Folium Hyptidis suaveolentis, Herba lychnidis coronatae, Herba hedyotis costatae and Radix cynanchi wilfordii.Whole compositions of the medicament for the treatment of herpes zoster of the present invention are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.

Description

A kind of medicament for the treatment of herpes zoster
The divisional application of the patent of invention of " a kind of medicament for the treatment of herpes zoster " that the present invention is application number is 201310560960.9, the applying date, to be November 12, denomination of invention in 2013 be.
Technical field
The present invention relates to department of dermatologry field, relate in particular to a kind of medicament for the treatment of herpes zoster.
Background technology
Herpes zoster is a kind of dermatosis caused by virus, and any position of health can occur.Be apt to occur in the areal area of nervi trigeminus, nervi vertebralis, intercostal nerves and waist sacral nerves, because it invades neural, unbearably, treatment is particularly important in time for patient's sufferings.Herpes zoster belongs to " herpes zoster ", " skirt-roof dragon ", " Fructus Vitis viniferae stream " category.Many because of feelings will internal injury, stagnation of QI due to depression of the liver, with the passing of time fire-transformation, liver and gall fire is contained, and be subject to poison evil outward and send out, with purging liver and gallbladder, detoxification and promoting urination, reducing swelling and alleviating pain is the rule for the treatment of.These become the newtype drug basis finding treatment herpes zoster.Complete the present invention on this basis.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of herpes zoster.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of herpes zoster, it is made up of the material of following weight proportioning: Herba Aletridis Khasianae 6 parts, Cortex schizophragmatis integrifolii radicis 8 parts, Radix Codonopsis lanceolatae 5 parts, Radix Fici comatae 3 parts, 9 parts, Flos Mume, Cissus pteroclada Hayata 5 parts, Ilex purpurea Hassk.[I.chinensis Sims 8 parts, Ramulus et Folium Bischofiae Javanicae 3 parts, Parmelia tinctorum Despr. 2 parts, Herba hyperici attenuati 3 parts, Herba Reineckeae Carneae 8 parts, sanicle 3 parts, Herba Lespedezae Cuneatae 2 parts, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke 5 parts, Cortex Xylosmae japonici 5 parts, Rhizoma disporopsis pernyi 2 parts, Lombardy poplar 7 parts, 6 parts, clothing of failing, Caulis et Folium Hyptidis suaveolentis 3 parts, Herba lychnidis coronatae 5 parts, Herba hedyotis costatae 6 parts and Radix cynanchi wilfordii 8 parts.
More preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.
In the present compositions, Herba Aletridis Khasianae, Cortex schizophragmatis integrifolii radicis, Radix Codonopsis lanceolatae, Radix Fici comatae are monarch drug; Flos Mume, Cissus pteroclada Hayata, Ilex purpurea Hassk.[I.chinensis Sims, Ramulus et Folium Bischofiae Javanicae, Parmelia tinctorum Despr., Herba hyperici attenuati are ministerial drug; Herba Reineckeae Carneae, sanicle, Herba Lespedezae Cuneatae, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke, Cortex Xylosmae japonici, Rhizoma disporopsis pernyi, Lombardy poplar are adjuvant drug; Fail clothing, Caulis et Folium Hyptidis suaveolentis, Herba lychnidis coronatae, Herba hedyotis costatae and Radix cynanchi wilfordii for making medicine; Compositions of the present invention plays drug effect best by monarch synergism.
Whole compositions of the medicament for the treatment of herpes zoster of the present invention are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment decoction of the present invention
Take Herba Aletridis Khasianae 6 grams, Cortex schizophragmatis integrifolii radicis 8 grams, Radix Codonopsis lanceolatae 5 grams, Radix Fici comatae 3 grams, 9 grams, Flos Mume, Cissus pteroclada Hayata 5 grams, Ilex purpurea Hassk.[I.chinensis Sims 8 grams, Ramulus et Folium Bischofiae Javanicae 3 grams, Parmelia tinctorum Despr. 2 grams, Herba hyperici attenuati 3 grams, Herba Reineckeae Carneae 8 grams, sanicle 3 grams, Herba Lespedezae Cuneatae 2 grams, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke 5 grams, Cortex Xylosmae japonici 5 grams, Rhizoma disporopsis pernyi 2 grams, Lombardy poplar 7 grams, 6 grams, clothing of failing, Caulis et Folium Hyptidis suaveolentis 3 grams, Herba lychnidis coronatae 5 grams, Herba hedyotis costatae 6 grams and Radix cynanchi wilfordii 8 grams, add 5000 milliliters, water, heat 6 hours at 80 DEG C in the flask that condensing tube is housed, filter, filtrate is decoction of the present invention.
Experimental example
Diagnostic criteria
Clinical diagnosis all meets the diagnostic criteria of " Chinese medical disease Standardization of diagnosis and curative effect " middle herpes zoster that State Administration of Traditional Chinese Medicine issues.1. skin lesion mostly is the water scar of Semen phaseoli radiati or Semen Glycines size, assembles a place or many places in threes and fours, is arranged in band shape, substrate flushing, even serious time can occur that petechia, blood scar are downright bad; 2. from the beginning of skin rubefaction, and skin irritation or burning sensation is accompanied, can with grade fever, the General Symptomies such as tired discomfort, inappetence.Conscious pain is obvious, has severe pain unbearably and rear something lost pain symptom.
Choose patient 100 example meeting above-mentioned diagnostic criteria, wherein, man 50 example, female 50 example, the oldest person is 60 years old, and reckling is 28 years old, average 41 years old.
The decoction of preparation in embodiment 1 is used to treat, every day 2 times, oral 50 milliliters at every turn.Treat 7 days is 1 course for the treatment of.
Observation of curative effect standard
" the Chinese medicine card Standardization of diagnosis and curative effect " issued with reference to State Administration of Traditional Chinese Medicine is drafted.Recovery from illness: deflorescence, clinical symptom disappearance, without pain sequela; Take a turn for the better: deflorescence about 50%, pain obviously alleviates; Do not heal: deflorescence, less than 30%, still has pain malaise symptoms.
Therapeutic outcome
After a course for the treatment of of treatment, all patient's deflorescences, clinical symptom disappearance, without pain sequela, all meets the standard of recovery from illness.
Untoward reaction and toxic and side effects monitoring
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Setting human normal systolic pressure is between 90-140mmHg, diastolic pressure is between 60-90mmHg, human normal pulse is 60-100 beat/min, blood pressure, the pulse of patient is measured at treatments period, find that the blood pressure and pulse recorded is all within normal range, the phenomenon not exceeding normal interval occurs, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that this medicine does not have obvious toxic and side effects for human body.

Claims (1)

1. the purposes of compositions in the medicament of preparation treatment herpes zoster, it is characterized in that, described compositions is made up of the material of following weight proportioning: Herba Aletridis Khasianae 6 parts, Cortex schizophragmatis integrifolii radicis 8 parts, Radix Codonopsis lanceolatae 5 parts, Radix Fici comatae 3 parts, 9 parts, Flos Mume, Cissus pteroclada Hayata 5 parts, Ilex purpurea Hassk.[I.chinensis Sims 8 parts, Ramulus et Folium Bischofiae Javanicae 3 parts, Parmelia tinctorum Despr. 2 parts, Herba hyperici attenuati 3 parts, Herba Reineckeae Carneae 8 parts, sanicle 3 parts, Herba Lespedezae Cuneatae 2 parts, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke 5 parts, Cortex Xylosmae japonici 5 parts, Rhizoma disporopsis pernyi 2 parts, Lombardy poplar 7 parts, 6 parts, clothing of failing, Caulis et Folium Hyptidis suaveolentis 3 parts, Herba lychnidis coronatae 5 parts, Herba hedyotis costatae 6 parts and Radix cynanchi wilfordii 8 parts.
CN201410598374.8A 2013-11-12 2013-11-12 A kind of medicament for the treatment of herpes zoster Expired - Fee Related CN104306649B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104055895B (en) * 2014-06-26 2016-04-06 张海燕 A kind of Chinese medicine preparation for the treatment of Complicated by Malignancy herpes zoster
CN111494488A (en) * 2020-06-22 2020-08-07 成迎升 External liquid medicament for treating herpes zoster

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1054286C (en) * 1993-09-23 2000-07-12 邓辛贵 Medicine for relieving inflammation and pain
CN100998657A (en) * 2006-12-28 2007-07-18 江蕾 Traditional Chinese medicine for treating herpes zoster
CN101028358B (en) * 2007-04-04 2010-09-08 郝明泽 Oral Chinese medicinal composition for treating ribbon bleb
CN101347554B (en) * 2008-08-29 2010-12-08 刘运波 Chinese medicine for treating zoster
CN102614397B (en) * 2012-02-27 2013-09-18 戴明华 Preparation method for traditional Chinese medicine lotion for treating hemorrhagic type ecthyma

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