CN101389656A - 抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 - Google Patents
抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 Download PDFInfo
- Publication number
- CN101389656A CN101389656A CNA2006800533635A CN200680053363A CN101389656A CN 101389656 A CN101389656 A CN 101389656A CN A2006800533635 A CNA2006800533635 A CN A2006800533635A CN 200680053363 A CN200680053363 A CN 200680053363A CN 101389656 A CN101389656 A CN 101389656A
- Authority
- CN
- China
- Prior art keywords
- antibody
- record
- periosteum
- sequence number
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
Abstract
Description
No. | OD值 |
12345678910 | 0.410.370.680.240.330.320.330.320.120.3 |
Claims (34)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005380009 | 2005-12-28 | ||
JP380009/2005 | 2005-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101389656A true CN101389656A (zh) | 2009-03-18 |
Family
ID=38228283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2006800533635A Pending CN101389656A (zh) | 2005-12-28 | 2006-12-28 | 抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1978034B2 (zh) |
JP (1) | JP5019464B2 (zh) |
KR (1) | KR101363695B1 (zh) |
CN (1) | CN101389656A (zh) |
AU (1) | AU2006334029B2 (zh) |
BR (1) | BRPI0620747A2 (zh) |
CA (1) | CA2635849C (zh) |
RU (1) | RU2008130898A (zh) |
WO (1) | WO2007077934A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103688171A (zh) * | 2010-12-16 | 2014-03-26 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
WO2023036305A1 (zh) * | 2021-09-13 | 2023-03-16 | 沈阳眼产业技术研究院有限公司 | 抗periostin人源化单克隆抗体及其制备方法与应用 |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8017119B2 (en) | 2005-12-28 | 2011-09-13 | Daiichi Sankyo Company, Ltd. | Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved |
CA2690888C (en) * | 2007-06-27 | 2016-02-09 | Asubio Pharma Co., Ltd. | Cancer therapeutic composition comprising antibody against peptide encoded by exon-17 site of periostin |
EP2295599B1 (en) | 2008-06-05 | 2013-07-31 | Saga University | Method for detection of idiopathic interstitial pneumonia |
US20120004133A1 (en) * | 2009-02-20 | 2012-01-05 | The Johns Hopkins University | Method for the diagnosis of age-associated vascular disorders |
ES2618181T3 (es) * | 2009-02-24 | 2017-06-21 | Esbatech, An Alcon Biomedical Research Unit Llc | Métodos para identificar inmunoaglutinantes de antígenos de superficie celular |
JP5555940B2 (ja) * | 2010-04-14 | 2014-07-23 | 国立大学法人佐賀大学 | 増殖糖尿病網膜症の検出方法および予防・治療剤のスクリーニング方法 |
JP6183809B2 (ja) | 2011-09-06 | 2017-08-23 | 株式会社シノテスト | ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法 |
BR112014006135A2 (pt) | 2011-09-15 | 2017-06-13 | Medical & Biological Laboratories Co Ltd | marcador molecular para a detecção precoce do mesotelioma pleural maligno e métodos de sua análise de expressão com o uso de amostras de derramamento pleural e de sangue |
FR2992221A1 (fr) * | 2012-06-22 | 2013-12-27 | Centre Nat Rech Scient | Modification des effets immunomodulateurs des cellules |
US20150184155A1 (en) | 2012-07-18 | 2015-07-02 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for preventing and treating chronic kidney disease (ckd) |
JP6218088B2 (ja) * | 2013-03-08 | 2017-11-01 | 国立大学法人大阪大学 | ペリオスチンのExon−21部位によりコードされるペプチドに対する抗体及び該抗体を含む炎症関連疾患の予防又は治療用医薬組成物 |
CN106170497A (zh) * | 2014-02-07 | 2016-11-30 | 免疫医疗有限责任公司 | 检测人类骨膜蛋白的新型测定 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0710719T3 (da) | 1990-01-12 | 2007-07-09 | Amgen Fremont Inc | Frembringelse af xenogene antistoffer |
EP0814159B1 (en) | 1990-08-29 | 2005-07-27 | GenPharm International, Inc. | Transgenic mice capable of producing heterologous antibodies |
JPH05268982A (ja) | 1992-03-27 | 1993-10-19 | Hoechst Japan Ltd | 骨形成作用を有する新規な蛋白質およびその製造法 |
EP0754225A4 (en) | 1993-04-26 | 2001-01-31 | Genpharm Int | HETEROLOGIC ANTIBODY-PRODUCING TRANSGENIC NON-HUMAN ANIMALS |
IL154794A0 (en) | 2000-09-08 | 2003-10-31 | Daiichi Suntory Pharma Co Ltd | Remedies for heart failure |
JP2007504842A (ja) * | 2003-05-29 | 2007-03-08 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | 乳癌の同定、評価、予防、および治療のための組成物、キットおよび方法 |
WO2005019471A2 (en) * | 2003-08-13 | 2005-03-03 | Temple University Of The Commonwealth System Of Higher Education | Periostin-like factor: compositions and methods for making and using the same |
-
2006
- 2006-12-28 AU AU2006334029A patent/AU2006334029B2/en active Active
- 2006-12-28 CN CNA2006800533635A patent/CN101389656A/zh active Pending
- 2006-12-28 CA CA2635849A patent/CA2635849C/en active Active
- 2006-12-28 JP JP2007552991A patent/JP5019464B2/ja active Active
- 2006-12-28 KR KR1020087018312A patent/KR101363695B1/ko active IP Right Grant
- 2006-12-28 WO PCT/JP2006/326280 patent/WO2007077934A1/ja active Application Filing
- 2006-12-28 EP EP06843658.3A patent/EP1978034B2/en active Active
- 2006-12-28 BR BRPI0620747-2A patent/BRPI0620747A2/pt not_active IP Right Cessation
- 2006-12-28 RU RU2008130898/13A patent/RU2008130898A/ru not_active Application Discontinuation
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103688171A (zh) * | 2010-12-16 | 2014-03-26 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN105169390A (zh) * | 2010-12-16 | 2015-12-23 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN112168962A (zh) * | 2010-12-16 | 2021-01-05 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
WO2023036305A1 (zh) * | 2021-09-13 | 2023-03-16 | 沈阳眼产业技术研究院有限公司 | 抗periostin人源化单克隆抗体及其制备方法与应用 |
Also Published As
Publication number | Publication date |
---|---|
WO2007077934A1 (ja) | 2007-07-12 |
EP1978034A1 (en) | 2008-10-08 |
BRPI0620747A2 (pt) | 2011-11-22 |
CA2635849C (en) | 2017-05-09 |
KR101363695B1 (ko) | 2014-02-14 |
JP5019464B2 (ja) | 2012-09-05 |
EP1978034B1 (en) | 2014-09-17 |
JPWO2007077934A1 (ja) | 2009-06-11 |
KR20080099248A (ko) | 2008-11-12 |
AU2006334029A1 (en) | 2007-07-12 |
EP1978034B2 (en) | 2018-05-16 |
RU2008130898A (ru) | 2010-02-10 |
CA2635849A1 (en) | 2007-07-12 |
AU2006334029B2 (en) | 2013-01-31 |
EP1978034A4 (en) | 2010-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101389656A (zh) | 抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 | |
CN105101997B (zh) | 不减少血小板和不减少血红细胞的cd47抗体及其使用方法 | |
KR101429783B1 (ko) | 항 인간 α9 인테그린 항체와 그 용도 | |
CN101103044B (zh) | 抗α9整联蛋白抗体及其用途 | |
EP2168599B1 (en) | Cancer remedy containing antibody against peptide encoded by exon-17 of periostin | |
US8372957B2 (en) | Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved | |
CN107108738A (zh) | 抗cd3抗体、可活化抗cd3抗体、多特异性抗cd3抗体、多特异性可活化抗cd3抗体及其使用方法 | |
US20060178503A1 (en) | Antibody to an integrin heterodimer and/or a subunit thereof | |
JP2007523092A (ja) | 新脈管形成阻害のための方法および組成物 | |
US20190106484A1 (en) | Antibody against peptide encoded by exon-21 of periostin and pharmaceutical composition for preventing or treating inflammation-associated diseases containing the same | |
CN102675461A (zh) | 针对可溶型lox-1的单克隆抗体 | |
JP2008500004A (ja) | CD44vRAに対する抗体およびその使用方法 | |
JP4469180B2 (ja) | テネイシンw組成物およびその使用 | |
CN103201291B (zh) | 抗单链iv型胶原多肽抗体和包含其的用于诊断、预防或***的药物或药剂 | |
MX2008008584A (es) | Anticuerpo contra periostina, y una composicion farmaceutica que lo comprende para prevenir o tratar una enfermedad en donde esta involucrada periostina. | |
Ayalon | The structure and regulation of endothelial junctions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
ASS | Succession or assignment of patent right |
Owner name: SANKYO CO. Free format text: FORMER OWNER: ASUBIO PHARMA CO., LTD. Effective date: 20100907 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20100907 Address after: Tokyo, Japan Applicant after: Sankyo Co. Co-applicant after: National University Corporation Osaka University Address before: Tokyo, Japan Applicant before: Asubio Pharma Co., Ltd. Co-applicant before: National University Corporation Osaka University |
|
ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: UNIV OSAKA Effective date: 20130402 Owner name: UNIV OSAKA Free format text: FORMER OWNER: SANKYO CO. Effective date: 20130402 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20130402 Address after: Osaka Japan Applicant after: National University Corporation Osaka University Address before: Tokyo, Japan Applicant before: Sankyo Co. Applicant before: National University Corporation Osaka University |
|
C12 | Rejection of a patent application after its publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20090318 |