CL2014001564A1 - Metodo de cosecha de cultivo celular de un mamífero que comprende cultivar células de mamífero que expresan una proteína recombinante en un medio de cultivo celular por un tiempo predeterminado. - Google Patents
Metodo de cosecha de cultivo celular de un mamífero que comprende cultivar células de mamífero que expresan una proteína recombinante en un medio de cultivo celular por un tiempo predeterminado.Info
- Publication number
- CL2014001564A1 CL2014001564A1 CL2014001564A CL2014001564A CL2014001564A1 CL 2014001564 A1 CL2014001564 A1 CL 2014001564A1 CL 2014001564 A CL2014001564 A CL 2014001564A CL 2014001564 A CL2014001564 A CL 2014001564A CL 2014001564 A1 CL2014001564 A1 CL 2014001564A1
- Authority
- CL
- Chile
- Prior art keywords
- cell culture
- mammal
- express
- predetermined time
- mammalian cells
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 238000004113 cell culture Methods 0.000 title 1
- 239000006143 cell culture medium Substances 0.000 title 1
- 238000012258 culturing Methods 0.000 title 1
- 210000004962 mammalian cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/145—Extraction; Separation; Purification by extraction or solubilisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161576303P | 2011-12-15 | 2011-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2014001564A1 true CL2014001564A1 (es) | 2015-01-16 |
Family
ID=47559662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2014001564A CL2014001564A1 (es) | 2011-12-15 | 2014-06-13 | Metodo de cosecha de cultivo celular de un mamífero que comprende cultivar células de mamífero que expresan una proteína recombinante en un medio de cultivo celular por un tiempo predeterminado. |
Country Status (18)
Country | Link |
---|---|
US (2) | US9371554B2 (es) |
EP (1) | EP2791319B1 (es) |
JP (4) | JP2015504659A (es) |
KR (5) | KR20220084192A (es) |
CN (2) | CN113150060A (es) |
AR (1) | AR089231A1 (es) |
AU (4) | AU2012351926A1 (es) |
BR (1) | BR112014014116A2 (es) |
CA (1) | CA2859197C (es) |
CL (1) | CL2014001564A1 (es) |
EA (1) | EA201491144A1 (es) |
HK (1) | HK1199057A1 (es) |
IL (2) | IL233028B (es) |
MX (1) | MX353959B (es) |
SG (1) | SG11201403258VA (es) |
TW (1) | TWI576144B (es) |
WO (1) | WO2013090820A1 (es) |
ZA (1) | ZA201404351B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR089231A1 (es) * | 2011-12-15 | 2014-08-06 | Amgen Inc | Metodo de floculacion |
TWI707949B (zh) * | 2014-06-09 | 2020-10-21 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
FI20165282A (fi) * | 2016-04-01 | 2017-10-02 | Kemira Oyj | Menetelmä ja järjestelmä koaguloinnin ja/tai flokkuloinnin optimoimiseksi veden käsittelyprosessissa |
WO2017217930A1 (en) * | 2016-06-15 | 2017-12-21 | Agency For Science, Technology And Research | A method of enhancing the performance of chromatography methods for purification of proteins |
JP2021536241A (ja) * | 2018-08-30 | 2021-12-27 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 核酸を検出する方法 |
HU231498B1 (hu) | 2019-04-04 | 2024-05-28 | Richter Gedeon Nyrt | Immunglobulinok affinitás kromatográfiájának fejlesztése kötést megelőző flokkulálás alkalmazásával |
US11219843B2 (en) * | 2019-07-08 | 2022-01-11 | Nik Paya Karen Pharmed | Extraction of animal-derived pulmonary surfactants |
CN111068367A (zh) * | 2019-12-17 | 2020-04-28 | 青岛宝和信生物科技有限公司 | 植物/中药提取液及水处理连续自动化絮凝及分离工艺 |
GB2590721A (en) | 2019-12-31 | 2021-07-07 | Inst Jozef Stefan | Controlled aggregation of cells |
US20230331775A1 (en) | 2020-09-22 | 2023-10-19 | Basf Se | Method for recovering a protein from a fermentation broth comprising a high degree of lysed cells |
WO2024059235A2 (en) | 2022-09-16 | 2024-03-21 | Amgen Inc. | A method for harvesting products from perfusion cultures |
Family Cites Families (31)
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US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
AU588819B2 (en) | 1984-10-29 | 1989-09-28 | Immunex Corporation | Cloning of human granulocyte-macrophage colony stimulating factor gene |
US4968607A (en) | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
US5075222A (en) | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
WO1990005183A1 (en) | 1988-10-31 | 1990-05-17 | Immunex Corporation | Interleukin-4 receptors |
US5395760A (en) | 1989-09-05 | 1995-03-07 | Immunex Corporation | DNA encoding tumor necrosis factor-α and -β receptors |
EP1132471A3 (de) | 1989-09-12 | 2001-11-28 | F. Hoffmann-La Roche Ag | TNF-bindende Proteine |
US6204363B1 (en) | 1989-10-16 | 2001-03-20 | Amgen Inc. | Stem cell factor |
US5272064A (en) | 1989-12-19 | 1993-12-21 | Amgen Inc. | DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof |
US5149792A (en) | 1989-12-19 | 1992-09-22 | Amgen Inc. | Platelet-derived growth factor B chain analogs |
US5350683A (en) | 1990-06-05 | 1994-09-27 | Immunex Corporation | DNA encoding type II interleukin-1 receptors |
AU651596B2 (en) | 1990-06-05 | 1994-07-28 | Immunex Corporation | Type II interleukin-1 receptors |
PT672141E (pt) | 1992-10-23 | 2003-09-30 | Immunex Corp | Metodos de preparacao de proteinas oligomericas soluveis |
US5554512A (en) | 1993-05-24 | 1996-09-10 | Immunex Corporation | Ligands for flt3 receptors |
US5552316A (en) * | 1993-06-04 | 1996-09-03 | Environmental Marketing Services, Ltd. | Clarifying E. coli fermentation broths with a combination of anionic and cationic flocculants |
US5981713A (en) | 1994-10-13 | 1999-11-09 | Applied Research Systems Ars Holding N.V. | Antibodies to intereleukin-1 antagonists |
KR100510234B1 (ko) | 1995-06-29 | 2005-11-25 | 임뮤넥스 코포레이션 | 세포소멸을 유도하는 시토킨 |
US6613544B1 (en) | 1995-12-22 | 2003-09-02 | Amgen Inc. | Osteoprotegerin |
US6096728A (en) | 1996-02-09 | 2000-08-01 | Amgen Inc. | Composition and method for treating inflammatory diseases |
US6271349B1 (en) | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
US6337072B1 (en) | 1998-04-03 | 2002-01-08 | Hyseq, Inc. | Interleukin-1 receptor antagonist and recombinant production thereof |
GB9919187D0 (en) | 1999-08-14 | 1999-10-20 | Ciba Spec Chem Water Treat Ltd | Flocculation of cell material |
AU1920301A (en) | 1999-11-17 | 2001-05-30 | Immunex Corporation | Receptor activator of nf-kappa b |
EP1403274A1 (en) * | 2002-09-30 | 2004-03-31 | Meristem Therapeutics | Process for the purification of recombinant proteins from complex media and purified proteins obtained thereby |
WO2007035283A1 (en) * | 2005-09-15 | 2007-03-29 | Wyeth | Protein floculation using salts |
WO2008100578A2 (en) | 2007-02-14 | 2008-08-21 | Amgen Inc. | Method of isolating antibodies by precipitation |
EP1985305A1 (en) * | 2007-04-24 | 2008-10-29 | Vivalis | Duck embryonic derived stem cell lines for the production of viral vaccines |
KR101604877B1 (ko) * | 2008-02-14 | 2016-03-18 | 가부시키가이샤 진 테크노 사이언스 | 항adam-15항체 및 그의 이용 |
AU2010205007A1 (en) | 2009-01-13 | 2011-07-07 | Ge Healthcare Bio-Sciences Ab | Precipitation of biomolecules with negatively charged polymers |
AR089231A1 (es) * | 2011-12-15 | 2014-08-06 | Amgen Inc | Metodo de floculacion |
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2012
- 2012-12-13 AR ARP120104705A patent/AR089231A1/es unknown
- 2012-12-14 KR KR1020227019427A patent/KR20220084192A/ko active Application Filing
- 2012-12-14 BR BR112014014116A patent/BR112014014116A2/pt not_active Application Discontinuation
- 2012-12-14 KR KR1020197035609A patent/KR20190137944A/ko not_active IP Right Cessation
- 2012-12-14 WO PCT/US2012/069916 patent/WO2013090820A1/en active Application Filing
- 2012-12-14 MX MX2014007128A patent/MX353959B/es active IP Right Grant
- 2012-12-14 CN CN202110381379.5A patent/CN113150060A/zh active Pending
- 2012-12-14 KR KR1020217023322A patent/KR20210095723A/ko not_active Application Discontinuation
- 2012-12-14 KR KR1020147019193A patent/KR20140103320A/ko not_active Application Discontinuation
- 2012-12-14 SG SG11201403258VA patent/SG11201403258VA/en unknown
- 2012-12-14 US US14/365,496 patent/US9371554B2/en active Active
- 2012-12-14 TW TW101147676A patent/TWI576144B/zh active
- 2012-12-14 EA EA201491144A patent/EA201491144A1/ru unknown
- 2012-12-14 EP EP12815893.8A patent/EP2791319B1/en active Active
- 2012-12-14 CN CN201280069842.1A patent/CN104245922B/zh active Active
- 2012-12-14 AU AU2012351926A patent/AU2012351926A1/en not_active Abandoned
- 2012-12-14 KR KR1020237042787A patent/KR20230172040A/ko active Application Filing
- 2012-12-14 JP JP2014547521A patent/JP2015504659A/ja active Pending
- 2012-12-14 CA CA2859197A patent/CA2859197C/en active Active
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2014
- 2014-06-09 IL IL233028A patent/IL233028B/en active IP Right Grant
- 2014-06-12 ZA ZA2014/04351A patent/ZA201404351B/en unknown
- 2014-06-13 CL CL2014001564A patent/CL2014001564A1/es unknown
- 2014-12-09 HK HK14112366.5A patent/HK1199057A1/xx unknown
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2016
- 2016-06-20 US US15/187,460 patent/US20160297850A1/en not_active Abandoned
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2018
- 2018-06-22 AU AU2018204547A patent/AU2018204547B2/en active Active
- 2018-10-12 JP JP2018193329A patent/JP6998853B2/ja active Active
- 2018-12-12 IL IL263674A patent/IL263674A/en unknown
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2020
- 2020-11-09 AU AU2020267147A patent/AU2020267147B2/en active Active
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2021
- 2021-09-24 JP JP2021155652A patent/JP7274547B2/ja active Active
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2023
- 2023-04-28 JP JP2023074144A patent/JP2023099117A/ja active Pending
- 2023-08-23 AU AU2023219874A patent/AU2023219874A1/en active Pending
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