CA999003A - Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl) benzamides and thiobenzamides - Google Patents

Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl) benzamides and thiobenzamides

Info

Publication number
CA999003A
CA999003A CA167,654A CA167654A CA999003A CA 999003 A CA999003 A CA 999003A CA 167654 A CA167654 A CA 167654A CA 999003 A CA999003 A CA 999003A
Authority
CA
Canada
Prior art keywords
thiobenzamides
benzamides
pyrrolidinyl
substituted
controlling emesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA167,654A
Other languages
English (en)
Other versions
CA167654S (en
Inventor
Albert D. Cale (Jr.)
Charles A. Leonard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Application granted granted Critical
Publication of CA999003A publication Critical patent/CA999003A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA167,654A 1972-04-03 1973-04-02 Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl) benzamides and thiobenzamides Expired CA999003A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24084072A 1972-04-03 1972-04-03
US34041773A 1973-03-12 1973-03-12

Publications (1)

Publication Number Publication Date
CA999003A true CA999003A (en) 1976-10-26

Family

ID=26933765

Family Applications (1)

Application Number Title Priority Date Filing Date
CA167,654A Expired CA999003A (en) 1972-04-03 1973-04-02 Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl) benzamides and thiobenzamides

Country Status (9)

Country Link
JP (4) JPS5620312B2 (nl)
CA (1) CA999003A (nl)
CH (1) CH580582A5 (nl)
DK (1) DK138491B (nl)
ES (1) ES413260A1 (nl)
NL (1) NL178318C (nl)
NO (1) NO142077C (nl)
PH (1) PH15259A (nl)
SE (3) SE402102B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362003B2 (en) 2002-11-27 2013-01-29 Incyte Corporation 3-aminopyrrolidine derivatives as modulators of chemokine receptors

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA732296B (en) * 1972-04-03 1974-11-27 Robins Co Inc A H Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
JPS5423113Y2 (nl) * 1974-10-08 1979-08-09
JPS5925784B2 (ja) * 1975-12-17 1984-06-21 山之内製薬株式会社 シンキナカルボンサンアミドユウドウタイノセイホウ
JPS5232815U (nl) * 1975-08-28 1977-03-08
JPS5925785B2 (ja) * 1976-01-01 1984-06-21 山之内製薬株式会社 新規なカルボン酸アミド誘導体
JPS5522699A (en) * 1979-08-10 1980-02-18 Yamanouchi Pharmaceut Co Ltd Novel 3-amino-1-benzylpyrrolidine derivative
JPS6316492U (nl) * 1986-07-18 1988-02-03
CN1147248A (zh) * 1994-04-28 1997-04-09 山之内制药株式会社 N-(3-吡咯烷基)苯甲酰胺衍生物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362003B2 (en) 2002-11-27 2013-01-29 Incyte Corporation 3-aminopyrrolidine derivatives as modulators of chemokine receptors
US8729063B2 (en) 2002-11-27 2014-05-20 Incyte Corporation 3-aminopyrrolidine derivatives as modulators of chemokine receptors

Also Published As

Publication number Publication date
SE402102B (sv) 1978-06-19
SE431869B (sv) 1984-03-05
DK138491C (nl) 1979-04-09
DK138491B (da) 1978-09-18
NO142077B (no) 1980-03-17
ES413260A1 (es) 1976-05-16
NL7304557A (nl) 1973-10-05
NL178318C (nl) 1986-03-03
SE8302193L (sv) 1983-04-19
JPS5182261A (en) 1976-07-19
PH15259A (en) 1982-11-02
NL178318B (nl) 1985-10-01
DE2316644B2 (de) 1977-04-28
SE8302193D0 (sv) 1983-04-19
CH580582A5 (nl) 1976-10-15
JPS5069067A (nl) 1975-06-09
JPS5620312B2 (nl) 1981-05-13
JPS5527905B2 (nl) 1980-07-24
SE431868B (sv) 1984-03-05
DE2316644A1 (de) 1973-10-18
JPS5069066A (nl) 1975-06-09
NO142077C (no) 1980-06-25
SE7711953L (sv) 1977-10-24
JPS4913165A (nl) 1974-02-05

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