JPS5522699A - Novel 3-amino-1-benzylpyrrolidine derivative - Google Patents
Novel 3-amino-1-benzylpyrrolidine derivativeInfo
- Publication number
- JPS5522699A JPS5522699A JP10183579A JP10183579A JPS5522699A JP S5522699 A JPS5522699 A JP S5522699A JP 10183579 A JP10183579 A JP 10183579A JP 10183579 A JP10183579 A JP 10183579A JP S5522699 A JPS5522699 A JP S5522699A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- benzyl
- amino
- benzylpyrrolidine
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrrole Compounds (AREA)
Abstract
NEW MATERIAL:3-Amino-1-benzylpyrrolidine derivative (salt) of formula I (R is lower alkyl).
EXAMPLE: 3-Amino-1-benzyl-2-methylpyrrolidine.
USE: An intermediate of N-(1-benzyl-3-pyrrolidinyl)benzamide derivative which is an anti-psychotic agent.
PROCESS: The objective compound I is prepared by (1) reacting an ethanol solution of a 1-benzyl-3-pyrrolidone derivative II with hydroxylamine hydrochloride (pref. aqueous solution) in the presence of a base such as sodium carbonate, etc., and (2) reducing the resulting 1-benzyl-3-hydroxyiminopyrrolidine derivative III with hydrogen, etc. in the presence of a catalyst such as Raney nickel, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10183579A JPS5522699A (en) | 1979-08-10 | 1979-08-10 | Novel 3-amino-1-benzylpyrrolidine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10183579A JPS5522699A (en) | 1979-08-10 | 1979-08-10 | Novel 3-amino-1-benzylpyrrolidine derivative |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7851877A Division JPS5414965A (en) | 1977-07-01 | 1977-07-01 | Novel carboxylic acid derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5522699A true JPS5522699A (en) | 1980-02-18 |
JPS5618593B2 JPS5618593B2 (en) | 1981-04-30 |
Family
ID=14311133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10183579A Granted JPS5522699A (en) | 1979-08-10 | 1979-08-10 | Novel 3-amino-1-benzylpyrrolidine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5522699A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0132845A2 (en) | 1983-07-27 | 1985-02-13 | Dainippon Pharmaceutical Co., Ltd. | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof |
US4910319A (en) * | 1987-10-02 | 1990-03-20 | Bayer Aktiengesellschaft | Process for preparing 3-amino-1-benzylpyrrolidines |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4913165A (en) * | 1972-04-03 | 1974-02-05 |
-
1979
- 1979-08-10 JP JP10183579A patent/JPS5522699A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4913165A (en) * | 1972-04-03 | 1974-02-05 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0132845A2 (en) | 1983-07-27 | 1985-02-13 | Dainippon Pharmaceutical Co., Ltd. | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof |
US4910319A (en) * | 1987-10-02 | 1990-03-20 | Bayer Aktiengesellschaft | Process for preparing 3-amino-1-benzylpyrrolidines |
Also Published As
Publication number | Publication date |
---|---|
JPS5618593B2 (en) | 1981-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5677267A (en) | Novel isoxazole derivative and its preparation | |
ES8300112A1 (en) | their starting compounds and their preparation. | |
ES8503666A1 (en) | 1-Aryloxy-2,3,4,5-tetrahydro-3-benzazepines, a process for preparing the same and their use as medicaments. | |
GB1111988A (en) | 2',3'-dideoxyriboside-2',3'-olefins | |
ES8308543A1 (en) | Substituted 2-phenyl-2-(pyridyloxy)-ethyl amines and isosteric compounds, process for their preparation and use. | |
GB1395243A (en) | Process for preparing piperidine derivatives | |
BG60267B2 (en) | Process for the preparation of amidoxime derivatives | |
JPS5522699A (en) | Novel 3-amino-1-benzylpyrrolidine derivative | |
ES465537A1 (en) | Novel benzylalcohol derivatives and processes for preparing the same | |
AU631735B2 (en) | New process for the preparation of 1-(2,3,4-trimethoxybenzyl) piperazine by reductive amination | |
ES458957A1 (en) | 1-aryloxy-2 - hydroxy - 3 - aminopropanes and process for their preparation | |
IE780901L (en) | Tetrazolyl-piperidinyl amides | |
SE8302345D0 (en) | PLEUROMUTILIN DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | |
DE3460467D1 (en) | Hydroquinone derivatives and production thereof | |
TW339325B (en) | Novel azepane derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
GB950281A (en) | Benzamide derivatives | |
GB1082061A (en) | 1,3-ethanopiperazine and its derivatives | |
JPS55105666A (en) | Piperidine derivative | |
JPS5697268A (en) | Lower alkanoic acid derivative, salt and preparation thereof and preventing agent and remedy for diabetic complication containing the same as active constituent | |
JPS5618971A (en) | Alpha-halogeno-beta-benzosulfimidopropionitrile and its preparation | |
GB842925A (en) | Orally-effective antidiabetic compounds | |
JPS55141457A (en) | Novel benzylidene derivative | |
JPS567748A (en) | Preparation of benzamide | |
ES422085A1 (en) | Primary amino acylanilides methods of making the same and use as antiarrhythmic drugs | |
JPS55164670A (en) | Phenylthioalkylamine derivative |