JPS5522699A - Novel 3-amino-1-benzylpyrrolidine derivative - Google Patents

Novel 3-amino-1-benzylpyrrolidine derivative

Info

Publication number
JPS5522699A
JPS5522699A JP10183579A JP10183579A JPS5522699A JP S5522699 A JPS5522699 A JP S5522699A JP 10183579 A JP10183579 A JP 10183579A JP 10183579 A JP10183579 A JP 10183579A JP S5522699 A JPS5522699 A JP S5522699A
Authority
JP
Japan
Prior art keywords
derivative
benzyl
amino
benzylpyrrolidine
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10183579A
Other languages
Japanese (ja)
Other versions
JPS5618593B2 (en
Inventor
Mutsuo Takashima
Sumio Iwanami
Shinji Usuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to JP10183579A priority Critical patent/JPS5522699A/en
Publication of JPS5522699A publication Critical patent/JPS5522699A/en
Publication of JPS5618593B2 publication Critical patent/JPS5618593B2/ja
Granted legal-status Critical Current

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  • Pyrrole Compounds (AREA)

Abstract

NEW MATERIAL:3-Amino-1-benzylpyrrolidine derivative (salt) of formula I (R is lower alkyl).
EXAMPLE: 3-Amino-1-benzyl-2-methylpyrrolidine.
USE: An intermediate of N-(1-benzyl-3-pyrrolidinyl)benzamide derivative which is an anti-psychotic agent.
PROCESS: The objective compound I is prepared by (1) reacting an ethanol solution of a 1-benzyl-3-pyrrolidone derivative II with hydroxylamine hydrochloride (pref. aqueous solution) in the presence of a base such as sodium carbonate, etc., and (2) reducing the resulting 1-benzyl-3-hydroxyiminopyrrolidine derivative III with hydrogen, etc. in the presence of a catalyst such as Raney nickel, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP10183579A 1979-08-10 1979-08-10 Novel 3-amino-1-benzylpyrrolidine derivative Granted JPS5522699A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10183579A JPS5522699A (en) 1979-08-10 1979-08-10 Novel 3-amino-1-benzylpyrrolidine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10183579A JPS5522699A (en) 1979-08-10 1979-08-10 Novel 3-amino-1-benzylpyrrolidine derivative

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP7851877A Division JPS5414965A (en) 1977-07-01 1977-07-01 Novel carboxylic acid derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5522699A true JPS5522699A (en) 1980-02-18
JPS5618593B2 JPS5618593B2 (en) 1981-04-30

Family

ID=14311133

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10183579A Granted JPS5522699A (en) 1979-08-10 1979-08-10 Novel 3-amino-1-benzylpyrrolidine derivative

Country Status (1)

Country Link
JP (1) JPS5522699A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132845A2 (en) 1983-07-27 1985-02-13 Dainippon Pharmaceutical Co., Ltd. Novel 1,8-Naphthyridine derivatives, and process for preparation thereof
US4910319A (en) * 1987-10-02 1990-03-20 Bayer Aktiengesellschaft Process for preparing 3-amino-1-benzylpyrrolidines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4913165A (en) * 1972-04-03 1974-02-05

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4913165A (en) * 1972-04-03 1974-02-05

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0132845A2 (en) 1983-07-27 1985-02-13 Dainippon Pharmaceutical Co., Ltd. Novel 1,8-Naphthyridine derivatives, and process for preparation thereof
US4910319A (en) * 1987-10-02 1990-03-20 Bayer Aktiengesellschaft Process for preparing 3-amino-1-benzylpyrrolidines

Also Published As

Publication number Publication date
JPS5618593B2 (en) 1981-04-30

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