SE8302193L - N-(1-substituerade-3-pyrrolidinyl)-bensamider och tiobensamider - Google Patents

N-(1-substituerade-3-pyrrolidinyl)-bensamider och tiobensamider

Info

Publication number
SE8302193L
SE8302193L SE8302193A SE8302193A SE8302193L SE 8302193 L SE8302193 L SE 8302193L SE 8302193 A SE8302193 A SE 8302193A SE 8302193 A SE8302193 A SE 8302193A SE 8302193 L SE8302193 L SE 8302193L
Authority
SE
Sweden
Prior art keywords
formula
substituted
thiobensamides
benzamides
pyrrolidinyl
Prior art date
Application number
SE8302193A
Other languages
English (en)
Other versions
SE431869B (sv
SE8302193D0 (sv
Inventor
Jr A D Cale
C A Leonard
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of SE8302193L publication Critical patent/SE8302193L/sv
Publication of SE8302193D0 publication Critical patent/SE8302193D0/sv
Publication of SE431869B publication Critical patent/SE431869B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Claims (1)

1. Patentkrav POrfarande for framstgllning av en forening med formeln 2 f'ar reagera med en bensoylklorid med formeln Cl-C dgr R2 betecknar vats, 3:gyre alkyl, lagre alkoxi, halogen, nitro, monoalkylamino, dialkylamino, merkaptometyl, aoetamido, sulfamoyl, cyano, Ivarvio nar R2 betecknar amino eller acetamido istgllet anvAndest 'svarande fbrening innehallande en nitrogrupp sedan utsattes Zr- hydroxi, bensyloxi, trifluormetyl,kannetecknat av att en forening med formelnkatalytisk hydrering till en aminogrupp och eventuollt acyleras till onskad acetaminogrupp.
SE8302193A 1972-04-03 1983-04-19 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan SE431869B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24084072A 1972-04-03 1972-04-03
US34041773A 1973-03-12 1973-03-12

Publications (3)

Publication Number Publication Date
SE8302193L true SE8302193L (sv) 1983-04-19
SE8302193D0 SE8302193D0 (sv) 1983-04-19
SE431869B SE431869B (sv) 1984-03-05

Family

ID=26933765

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7304619A SE402102B (sv) 1972-04-03 1973-04-02 Forfarande for framstellning av 4-amino-n-(1-cyklohexyl-3-pyrrolidinyl)-n-alkyl-bensamider, med verdefulla terapeutiska egenskaper
SE7711953A SE431868B (sv) 1972-04-03 1977-10-24 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan
SE8302193A SE431869B (sv) 1972-04-03 1983-04-19 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7304619A SE402102B (sv) 1972-04-03 1973-04-02 Forfarande for framstellning av 4-amino-n-(1-cyklohexyl-3-pyrrolidinyl)-n-alkyl-bensamider, med verdefulla terapeutiska egenskaper
SE7711953A SE431868B (sv) 1972-04-03 1977-10-24 Forfarande for framstellning av n-(1-cyklohexyl-3-pyrrolidinyl)-bensamider med antiemetisk verkan

Country Status (9)

Country Link
JP (4) JPS5620312B2 (sv)
CA (1) CA999003A (sv)
CH (1) CH580582A5 (sv)
DK (1) DK138491B (sv)
ES (1) ES413260A1 (sv)
NL (1) NL178318C (sv)
NO (1) NO142077C (sv)
PH (1) PH15259A (sv)
SE (3) SE402102B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA732296B (en) * 1972-04-03 1974-11-27 Robins Co Inc A H Method for controlling emesis with n-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
JPS5423113Y2 (sv) * 1974-10-08 1979-08-09
JPS5925784B2 (ja) * 1975-12-17 1984-06-21 山之内製薬株式会社 シンキナカルボンサンアミドユウドウタイノセイホウ
JPS5232815U (sv) * 1975-08-28 1977-03-08
JPS5925785B2 (ja) * 1976-01-01 1984-06-21 山之内製薬株式会社 新規なカルボン酸アミド誘導体
JPS5522699A (en) * 1979-08-10 1980-02-18 Yamanouchi Pharmaceut Co Ltd Novel 3-amino-1-benzylpyrrolidine derivative
JPS6316492U (sv) * 1986-07-18 1988-02-03
WO1995029891A1 (fr) * 1994-04-28 1995-11-09 Yamanouchi Pharmaceutical Co., Ltd. Derive de n-(3-pyrrolidinyl)benzamide
RU2355679C2 (ru) 2002-11-27 2009-05-20 Инсайт Корпорейшн Производные 3-аминопирролидина в качестве модуляторов рецепторов хемокинов

Also Published As

Publication number Publication date
DE2316644A1 (de) 1973-10-18
JPS5527905B2 (sv) 1980-07-24
SE431869B (sv) 1984-03-05
DE2316644B2 (de) 1977-04-28
JPS5069067A (sv) 1975-06-09
NL178318B (nl) 1985-10-01
NL7304557A (sv) 1973-10-05
JPS4913165A (sv) 1974-02-05
DK138491C (sv) 1979-04-09
SE7711953L (sv) 1977-10-24
NL178318C (nl) 1986-03-03
SE431868B (sv) 1984-03-05
JPS5069066A (sv) 1975-06-09
JPS5182261A (en) 1976-07-19
DK138491B (da) 1978-09-18
SE8302193D0 (sv) 1983-04-19
CH580582A5 (sv) 1976-10-15
JPS5620312B2 (sv) 1981-05-13
ES413260A1 (es) 1976-05-16
NO142077C (no) 1980-06-25
NO142077B (no) 1980-03-17
CA999003A (en) 1976-10-26
PH15259A (en) 1982-11-02
SE402102B (sv) 1978-06-19

Similar Documents

Publication Publication Date Title
ES462065A1 (es) Procedimiento para la preparacion de derivados de tiazolidi-na.
SE7800322L (sv) Anvendning av sampolyamider innehallande kaprolaktam, laurinlaktam och 11-aminoundekansyra for varmpresslimning
SE8302193L (sv) N-(1-substituerade-3-pyrrolidinyl)-bensamider och tiobensamider
IE43653L (en) Sequestration of oxygen dissolved in water
NL7409439A (nl) Werkwijze voor het bereiden van tricyclisch gesubstitueerde aminoalkoholen en hun niet-toxi- sche zouten.
IE40335B1 (en) Pyrazole derivatives, process for their preparation and their use as medicaments
GB1386150A (en) 6-acylaminophenyl-4,5-dihydropyridazones
GB1371688A (en) Process for preparing benzoxazolones-2- and benzothiazolones-2
GB1096006A (en) Substituted biurets
GB1124157A (en) Novel benzdiaz[1,4] epine derivatives and a process for the manufacture thereof
ES450382A1 (es) Procedimiento para preparar derivados de acido indanacetico.
ES394885A1 (es) Un procedimiento para preparar derivados de acido fluoreno-2-acetico.
ES410313A2 (es) Procedimiento para lapreparacion de 6,7-dimetoxi-quinazoli-nonas.
ES459214A1 (es) Procedimiento para la preparacion de una solucion sobresatu-rada de dinitrato de isosorbita.
CH613938A5 (en) Process for the preparation of N-(2-amino-3,5-dibromobenzyl)-N-methylcyclohexylamine, and the compound prepared by the process
DK138320B (da) Analogifremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller farmaceutisk anvendelige syreadditionssalte deraf.
DK135423B (da) Analogifremgangsmåde til fremstilling af antirhinovirale 2,5-bis-substituerede amino-1,3,4,-thiadiazoler eller farmaceutisk acceptable syreadditionssalte deraf.
ATA555874A (de) Verfahren zur herstellung des neuen 6-(n-methyl-amindocarbonyloxymethyl)-2-pyridylmethylesters der 2-(p-chlorphenoxy)-2,2-dimethylessigsaure und seiner saureadditionssalze
AT299159B (de) Verfahren zur Herstellung des neuen N<1>-tyrosin-N<2>-(2,3,4-trihydroxybenzyl)-hydrazids und dessen Säureadditionssalze
ES285855A1 (es) Un procedimiento para la fabricación de derivados benzodiazepínicos
GB1105492A (en) Improvements in or relating to novel 3-tropanyl 2-phenylacrylate derivatives
AT299158B (de) Verfahren zur Herstellung des neuen N<1>-L-Serin-N<2>-(2,3,4-trihydroxybenzyl)-hydrazids sowie dessen Säureadditionssalze
GB1470748A (en) 6-2-pyridyl-4h-s-triazolo-4,3-a-1,4-benzodiazepines
ATA510574A (de) Verfahren zur herstellung von 2-amino-3,5-dibrom -n-methyl-n- cyclohexyl-benzylamin und dessen saureadditionssalzen
ES420456A1 (es) Un metodo para la produccion de derivados de benzodiazoci- na.

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8302193-1

Effective date: 19890427

Format of ref document f/p: F