CA2342796A1 - Medicaments preventifs/et remedes contre la defaillance de plusieurs organes - Google Patents
Medicaments preventifs/et remedes contre la defaillance de plusieurs organes Download PDFInfo
- Publication number
- CA2342796A1 CA2342796A1 CA002342796A CA2342796A CA2342796A1 CA 2342796 A1 CA2342796 A1 CA 2342796A1 CA 002342796 A CA002342796 A CA 002342796A CA 2342796 A CA2342796 A CA 2342796A CA 2342796 A1 CA2342796 A1 CA 2342796A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- substituent
- hydrogen atom
- thrombin
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
L'invention concerne des médicaments préventifs/et des remèdes contre la défaillance de plusieurs organes provoquée par l'aggravation de la septicémie, de l'hyperchémokinémie et des maladies hépatiques, contenant un agent antithrombine et/ou un inhibiteur de synthèse de la thrombine utilisé comme agent actif. Du fait qu'on peut les utiliser dans la prévention ou le traitement de maladies telles que la septicémie, la septicémie sévère, un choc septique et la défaillance de plusieurs organes, ces médicaments sont utiles pour traiter un traumatisme, une brûlure, un malaise dû à la chaleur, une infection sévère, etc., provoqués en particulier par les accidents de la route, en cas de soins d'urgence. Ces médicaments sont également utiles pour prévenir et traiter l'hyperchémokinémie et les maladies hépatiques.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10/249492 | 1998-09-03 | ||
JP10249492A JP2000080046A (ja) | 1998-09-03 | 1998-09-03 | 多臓器障害の予防・治療剤 |
PCT/JP1999/004783 WO2000013707A1 (fr) | 1998-09-03 | 1999-09-03 | Medicaments preventifs/et remedes contre la defaillance de plusieurs organes |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2342796A1 true CA2342796A1 (fr) | 2000-03-16 |
Family
ID=17193786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002342796A Abandoned CA2342796A1 (fr) | 1998-09-03 | 1999-09-03 | Medicaments preventifs/et remedes contre la defaillance de plusieurs organes |
Country Status (12)
Country | Link |
---|---|
US (1) | US6596754B1 (fr) |
EP (1) | EP1110556A4 (fr) |
JP (1) | JP2000080046A (fr) |
KR (1) | KR20010099628A (fr) |
CN (1) | CN1315873A (fr) |
AU (1) | AU5448699A (fr) |
CA (1) | CA2342796A1 (fr) |
ID (1) | ID28693A (fr) |
IL (1) | IL141402A0 (fr) |
NO (1) | NO20011096L (fr) |
TW (1) | TW533074B (fr) |
WO (1) | WO2000013707A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60233647D1 (de) | 2001-03-21 | 2009-10-22 | Eisai R&D Man Co Ltd | Reduziertes vitamin b2 enthaltende arzneimittel |
CA2507026A1 (fr) * | 2002-11-22 | 2004-06-10 | Takeda Pharmaceutical Company Limited | Derives d'imidazole, leur procede de production et d'utilisation |
EP2982668A3 (fr) | 2002-12-03 | 2016-04-13 | Pharmacyclics LLC | Dérivés de 2-(2-hydroxybiphényl-3-yl)-1h-benzoimidazole-5-carboxamidine en tant qu'inhibiteurs du facteur viia inhibitors pour le traitement de maladies thromboemboliques |
TWI396686B (zh) * | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
WO2006135790A1 (fr) * | 2005-06-09 | 2006-12-21 | Bristol-Myers Squibb Company | Methodes d'identification et de traitement d'individus presentant une proteine kit mutante |
EP4074282B1 (fr) | 2016-10-12 | 2024-04-17 | Solmetex LLC | Conteneur de recyclage dentaire |
CN110678555B (zh) | 2017-04-14 | 2023-10-13 | 比利时胶囊公司 | 制作普鲁兰的方法 |
CN110678170A (zh) | 2017-04-14 | 2020-01-10 | 比利时胶囊公司 | 普鲁兰多糖胶囊 |
US11679093B2 (en) | 2018-06-11 | 2023-06-20 | The Regents Of The University Of Colorado, A Body Corporate | 2-naphthimidamides, analogues thereof, and methods of treatment using same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466668A (en) * | 1989-04-28 | 1995-11-14 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
US5252725A (en) * | 1989-06-23 | 1993-10-12 | The Trustees Of The University Of Pennsylvania | α-1-antichymotrypsin, analogues and methods of production |
IL101062A0 (en) * | 1991-02-28 | 1992-11-15 | Erba Carlo Spa | Anti-thrombin polypeptides and their preparation |
ZA928276B (en) * | 1991-10-31 | 1993-05-06 | Daiichi Seiyaku Co | Aromatic amidine derivates and salts thereof. |
JP3388803B2 (ja) * | 1993-05-20 | 2003-03-24 | 第一製薬株式会社 | 光学活性7−アミジノナフタレン誘導体の製造法 |
-
1998
- 1998-09-03 JP JP10249492A patent/JP2000080046A/ja active Pending
-
1999
- 1999-09-03 CA CA002342796A patent/CA2342796A1/fr not_active Abandoned
- 1999-09-03 WO PCT/JP1999/004783 patent/WO2000013707A1/fr not_active Application Discontinuation
- 1999-09-03 CN CN99810429A patent/CN1315873A/zh active Pending
- 1999-09-03 ID IDW20010522A patent/ID28693A/id unknown
- 1999-09-03 US US09/786,236 patent/US6596754B1/en not_active Expired - Fee Related
- 1999-09-03 IL IL14140299A patent/IL141402A0/xx unknown
- 1999-09-03 AU AU54486/99A patent/AU5448699A/en not_active Abandoned
- 1999-09-03 KR KR1020017002214A patent/KR20010099628A/ko not_active Application Discontinuation
- 1999-09-03 EP EP99940643A patent/EP1110556A4/fr not_active Withdrawn
- 1999-09-03 TW TW088115221A patent/TW533074B/zh not_active IP Right Cessation
-
2001
- 2001-03-02 NO NO20011096A patent/NO20011096L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US6596754B1 (en) | 2003-07-22 |
IL141402A0 (en) | 2002-03-10 |
NO20011096D0 (no) | 2001-03-02 |
ID28693A (id) | 2001-06-28 |
WO2000013707A1 (fr) | 2000-03-16 |
KR20010099628A (ko) | 2001-11-09 |
NO20011096L (no) | 2001-03-02 |
AU5448699A (en) | 2000-03-27 |
TW533074B (en) | 2003-05-21 |
JP2000080046A (ja) | 2000-03-21 |
CN1315873A (zh) | 2001-10-03 |
EP1110556A1 (fr) | 2001-06-27 |
EP1110556A4 (fr) | 2004-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |