BRPI0813139A2 - Peptídeo glp-1 com adição de uma cadeia oligossacarídea - Google Patents

Peptídeo glp-1 com adição de uma cadeia oligossacarídea

Info

Publication number
BRPI0813139A2
BRPI0813139A2 BRPI0813139-2A2A BRPI0813139A BRPI0813139A2 BR PI0813139 A2 BRPI0813139 A2 BR PI0813139A2 BR PI0813139 A BRPI0813139 A BR PI0813139A BR PI0813139 A2 BRPI0813139 A2 BR PI0813139A2
Authority
BR
Brazil
Prior art keywords
oligosacaride
glp
peptide
chain
addition
Prior art date
Application number
BRPI0813139-2A2A
Other languages
English (en)
Inventor
Yasuhiro Kajihara
Izumi Sakamoto
Takashi Tsuji
Yuri Nambu
Kazuhiro Fukae
Katsunari Tezuka
Hiroaki Asai
Original Assignee
Otsuka Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of BRPI0813139A2 publication Critical patent/BRPI0813139A2/pt
Publication of BRPI0813139A8 publication Critical patent/BRPI0813139A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
BRPI0813139A 2007-06-19 2008-06-17 peptídeo glp-1 com adição de cadeia oligossacarídea BRPI0813139A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007160951 2007-06-19
PCT/JP2008/001554 WO2008155900A1 (ja) 2007-06-19 2008-06-17 糖鎖付加glp-1ペプチド

Publications (2)

Publication Number Publication Date
BRPI0813139A2 true BRPI0813139A2 (pt) 2015-02-18
BRPI0813139A8 BRPI0813139A8 (pt) 2019-01-29

Family

ID=40156064

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813139A BRPI0813139A8 (pt) 2007-06-19 2008-06-17 peptídeo glp-1 com adição de cadeia oligossacarídea

Country Status (13)

Country Link
US (3) US7985731B2 (pt)
EP (1) EP2172479B1 (pt)
JP (1) JP5646848B2 (pt)
KR (1) KR20100049032A (pt)
CN (1) CN102015761A (pt)
AU (1) AU2008264750C1 (pt)
BR (1) BRPI0813139A8 (pt)
CA (1) CA2696615A1 (pt)
DK (1) DK2172479T3 (pt)
RU (1) RU2539829C2 (pt)
SG (1) SG178797A1 (pt)
TW (1) TWI423821B (pt)
WO (1) WO2008155900A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2539829C2 (ru) * 2007-06-19 2015-01-27 ГЛИТЕК,ИНК.,Япония Пептид glp-1 с присоединенной олигосахаридной цепью
CN102083854A (zh) * 2008-06-17 2011-06-01 大塚化学株式会社 附加了糖链的glp-1肽
KR20120101037A (ko) * 2009-10-30 2012-09-12 오츠카 가가쿠 가부시키가이샤 항원성 ｇｌｐ?１ 아날로그의 당쇄 부가체
WO2011162830A2 (en) * 2010-06-24 2011-12-29 Biousian Biosystems, Inc. Glucagon-like peptide-1 glycopeptides
EP2657244B8 (en) * 2010-12-22 2016-08-31 Ajinomoto Co., Inc. Glycoside compounds as glp-1 secretion promoting agents
CN102718858B (zh) * 2011-03-29 2014-07-02 天津药物研究院 胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
RU2624034C2 (ru) * 2011-09-04 2017-06-30 Глитек, Инк. Гликозилированные полипептиды и лекарственные композиции, содержащие данные полипептиды
CN102321170B (zh) * 2011-09-14 2013-11-13 深圳翰宇药业股份有限公司 利拉鲁肽变构体及其缀合物
WO2013047846A1 (ja) 2011-10-01 2013-04-04 株式会社糖鎖工学研究所 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物
DK2924053T3 (da) * 2012-11-22 2020-12-14 Glytech Inc Glycosyleret linker, forbindelse, der indeholder glycosyleret linker-del og fysiologisk aktiv stofdel eller salt deraf, og fremgangsmåder til fremstilling af forbindelsen eller saltet deraf
US10202469B2 (en) 2012-11-30 2019-02-12 Glytech, Inc. Sugar chain-attached linker, compound containing sugar chain-attached linker and physiologically active substance or salt thereof, and method for producing same
RU2668163C2 (ru) * 2013-03-29 2018-09-26 Глитек, Инк. Полипептид, гликозилированный сиалилированной сахарной цепью
PE20230304A1 (es) 2014-12-30 2023-02-13 Hanmi Pharm Ind Co Ltd Derivados de glucagon como agentes hipoglucemicos y antiobesidad
AR105485A1 (es) 2015-06-30 2017-10-11 Hanmi Pharm Ind Co Ltd Derivado de glucagón y una composición que comprende un conjugado de acción prolongada del mismo
CR20180380A (es) 2015-12-31 2018-12-07 Hanmi Pharm Ind Co Ltd Agosnista triple de receptores de glucagón/glp-1/gip
BR112018077457A2 (pt) 2016-06-29 2019-04-02 Hanmi Pharm. Co., Ltd. composição farmacêutica para evitar ou tratar hiperinsulinismo congênito e seu método, hipoglicemia e seu método, síndrome metabólica e seu método e peptídeo isolado
CN115380043A (zh) * 2019-08-13 2022-11-22 安医健有限公司 艾塞那肽类似物及其用途
PE20221595A1 (es) * 2020-01-13 2022-10-10 Hanmi Pharm Ind Co Ltd Uso terapeutico de un conjugado de accion prolongada de un triple agonista que tiene actividad en todos los receptores de glucagon/glp-1/gip para enfermedades pulmonares
CN115463208B (zh) * 2021-10-09 2023-05-30 上海海赜生物科技有限公司 一种口服降糖组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943763B2 (en) 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
US7772188B2 (en) * 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
PT1605897E (pt) 2003-03-19 2012-09-10 Lilly Co Eli Compostos de glp-1 ligado a polietilenoglicol
SI1641823T1 (sl) * 2003-06-12 2011-12-30 Lilly Co Eli Fuzijski proteini analogni glp-1
CN1829742B (zh) * 2003-07-28 2010-06-09 大塚化学株式会社 氨基化复合型糖链衍生物及其制造方法
JP2005095331A (ja) 2003-09-24 2005-04-14 Ihara Suisan Kk 魚皮真皮コラーゲンを含有する発泡体シートおよびその用途
EP1771066A2 (en) * 2004-07-13 2007-04-11 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 glp-1
EP1961764B1 (en) 2005-11-30 2011-05-11 Shionogi Co., Ltd. Sugar chain adduct of peptide and pharmaceutical comprising the same as active ingredient
RU2539829C2 (ru) * 2007-06-19 2015-01-27 ГЛИТЕК,ИНК.,Япония Пептид glp-1 с присоединенной олигосахаридной цепью

Also Published As

Publication number Publication date
WO2008155900A1 (ja) 2008-12-24
EP2172479A4 (en) 2011-08-24
EP2172479A1 (en) 2010-04-07
EP2172479B1 (en) 2016-09-14
RU2539829C2 (ru) 2015-01-27
JP5646848B2 (ja) 2014-12-24
CN102015761A (zh) 2011-04-13
TWI423821B (zh) 2014-01-21
AU2008264750B2 (en) 2012-07-05
US20090111739A1 (en) 2009-04-30
US8507429B2 (en) 2013-08-13
RU2010101331A (ru) 2011-07-27
AU2008264750A1 (en) 2008-12-24
DK2172479T3 (en) 2016-12-19
JPWO2008155900A1 (ja) 2010-08-26
TW200902068A (en) 2009-01-16
US20110245166A1 (en) 2011-10-06
CA2696615A1 (en) 2008-12-24
US7985731B2 (en) 2011-07-26
KR20100049032A (ko) 2010-05-11
AU2008264750C1 (en) 2013-01-10
US20130345129A1 (en) 2013-12-26
SG178797A1 (en) 2012-03-29
BRPI0813139A8 (pt) 2019-01-29

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: GLYTECH, INC. (JP)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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