BRPI0513903A - derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos - Google Patents

derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos

Info

Publication number
BRPI0513903A
BRPI0513903A BRPI0513903-1A BRPI0513903A BRPI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A BR PI0513903 A BRPI0513903 A BR PI0513903A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
ketolide derivatives
same
preparation processes
antimicrobial agents
Prior art date
Application number
BRPI0513903-1A
Other languages
English (en)
Inventor
Biswajit Das
Mohammad Salman
Atul Kashinath Hajare
Ramadass Venkataramanan
Rita Katoch
Rajesh Kumar
Gobind Singh Kapkoti
Anjan Chakrabarti
Anish Bandyopadhyay
Santosh Haribhau Kurhade
Yogesh Baban Surase
Ashok Rattan
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of BRPI0513903A publication Critical patent/BRPI0513903A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

DERIVADOS DE CETOLìDEOS úTEIS COMO AGENTES ANTIMICROBIANOS, SEUS PROCESSOS DE PREPARAçãO E COMPOSIçõES FARMACêUTICAS COMPREENDENDO OS MESMOS. A presente invenção refere-se a derivados de cetolídeos, os quais podem ser usados como agentes bacterianos. Particularmente, os compostos aqui descritos podem ser usados no tratamento ou na prevenção de condições causadas ou influenciadas por bactérias Gram-positivas, Gram-negativas ou anaeróbicas, mais particularmente contra, por exemplo, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus ou Enterobactericeae. A presente invenção refere-se ainda a processos preparação dos referidos derivados de cetolídeos, composições farmacêuticas dos mesmos e a métodos tratamento de infecções bacterianas.
BRPI0513903-1A 2004-07-28 2005-07-28 derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos BRPI0513903A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1400DE2004 2004-07-28
IN1388DE2005 2005-05-30
PCT/US2005/027875 WO2006080954A1 (en) 2004-07-28 2005-07-28 Ketolide derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
BRPI0513903A true BRPI0513903A (pt) 2008-05-20

Family

ID=36480874

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0513903-1A BRPI0513903A (pt) 2004-07-28 2005-07-28 derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos

Country Status (6)

Country Link
US (1) US20080287376A1 (pt)
EP (1) EP1794171A2 (pt)
JP (1) JP2008508322A (pt)
BR (1) BRPI0513903A (pt)
RU (1) RU2397987C2 (pt)
WO (1) WO2006080954A1 (pt)

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PL1836211T3 (pl) 2004-12-21 2010-07-30 Pfizer Prod Inc Makrolidy
WO2007060627A2 (en) 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Use of macrolide derivatives for treating acne
US20090130225A1 (en) * 2005-11-23 2009-05-21 Anjan Chakrabarti Macrolides derivatives as antibacterial agents
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
NZ600635A (en) * 2007-09-17 2013-06-28 Enanta Pharm Inc 6, 11-bridged biaryl macrolides
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
EP2358379B1 (en) 2008-10-24 2015-12-16 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
WO2010096051A1 (en) * 2009-02-18 2010-08-26 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl amide macrolide derivatives
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
KR20180101643A (ko) 2010-03-22 2018-09-12 셈프라 파마슈티컬스, 인크. 매크로라이드의 결정 형태들 및 그 용도들
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
JP6042334B2 (ja) * 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
RU2658050C2 (ru) 2012-03-27 2018-06-19 Семпра Фармасьютикалз, Инк. Парентеральные составы для введения макролидных антибиотиков
CA2905975A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
JP6675973B2 (ja) 2013-03-15 2020-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗菌薬を調製するための集束的な方法
AU2014248014B2 (en) 2013-04-04 2018-11-08 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
CN105524132B (zh) * 2014-09-30 2019-07-02 中国医学科学院药物研究所 含有喹啉取代基的红霉素a酮内酯类抗生素衍生物、其制备方法及应用
US10633407B2 (en) * 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
WO2016154591A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
CN107129514B (zh) * 2016-03-02 2019-12-13 中国医学科学院药物研究所 红霉素a酮内酯类抗生素衍生物、其制备方法及应用

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FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
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EP1618119A2 (en) * 2003-04-25 2006-01-25 Chiron Corporation Pyridyl substituted ketolide antibiotics
US7271155B2 (en) * 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives

Also Published As

Publication number Publication date
WO2006080954A1 (en) 2006-08-03
US20080287376A1 (en) 2008-11-20
EP1794171A2 (en) 2007-06-13
RU2397987C2 (ru) 2010-08-27
RU2007107340A (ru) 2008-09-10
JP2008508322A (ja) 2008-03-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.