BR9607356A - Variantes de subtilisina carlsberg tendo adsorção diminuída e hidrólise aumentada - Google Patents

Variantes de subtilisina carlsberg tendo adsorção diminuída e hidrólise aumentada

Info

Publication number
BR9607356A
BR9607356A BR9607356A BR9607356A BR9607356A BR 9607356 A BR9607356 A BR 9607356A BR 9607356 A BR9607356 A BR 9607356A BR 9607356 A BR9607356 A BR 9607356A BR 9607356 A BR9607356 A BR 9607356A
Authority
BR
Brazil
Prior art keywords
subtilisin carlsberg
increased hydrolysis
decreased adsorption
carlsberg variants
variants
Prior art date
Application number
BR9607356A
Other languages
English (en)
Inventor
Philip Frederick Brode Iii
Bobby Lee Barnett
Donn Nelton Rubingh
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR9607356A publication Critical patent/BR9607356A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR9607356A 1995-03-08 1996-02-14 Variantes de subtilisina carlsberg tendo adsorção diminuída e hidrólise aumentada BR9607356A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/400,698 US6455295B1 (en) 1995-03-08 1995-03-08 Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
PCT/US1996/002168 WO1996028566A2 (en) 1995-03-08 1996-02-14 Subtilisin carlsberg variants having decreased adsorption and increased hydrolysis

Publications (1)

Publication Number Publication Date
BR9607356A true BR9607356A (pt) 1999-06-15

Family

ID=23584644

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9607356A BR9607356A (pt) 1995-03-08 1996-02-14 Variantes de subtilisina carlsberg tendo adsorção diminuída e hidrólise aumentada

Country Status (14)

Country Link
US (1) US6455295B1 (pt)
EP (1) EP0813596A2 (pt)
JP (1) JPH11501812A (pt)
CN (1) CN1183119A (pt)
AU (1) AU4868896A (pt)
BR (1) BR9607356A (pt)
CA (1) CA2214348C (pt)
CZ (1) CZ279397A3 (pt)
HU (1) HUP9800765A3 (pt)
IL (1) IL117266A0 (pt)
MA (1) MA23818A1 (pt)
MX (1) MX9706851A (pt)
WO (1) WO1996028566A2 (pt)
ZA (1) ZA961631B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
CA2270180C (en) * 1996-11-04 2011-01-11 Novo Nordisk A/S Subtilase variants and compositions
JPH10204500A (ja) * 1997-01-20 1998-08-04 Soft Kyukyu Corp:Kk 発泡錠剤洗浄剤
EP0913458B1 (en) * 1997-10-22 2004-06-16 The Procter & Gamble Company Liquid hard-surface cleaning compositions
ES2368718T3 (es) * 1997-10-23 2011-11-21 Danisco Us Inc. Variantes de subtilisina con múltiples sustituciones.
MA25044A1 (fr) * 1997-10-23 2000-10-01 Procter & Gamble Compositions de lavage contenant des variants de proteases multisubstituees.
US6773907B2 (en) 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
US6780629B2 (en) 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
EP1032655B1 (en) * 1997-11-21 2005-06-29 Novozymes A/S Protease variants and compositions
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6831053B1 (en) 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
CN1333822A (zh) * 1998-12-18 2002-01-30 诺沃奇梅兹有限公司 在活性位点环区具有额外氨基酸残基的i－s1和i－s2亚族枯草杆菌酶
KR100649912B1 (ko) * 1998-12-18 2006-11-24 노보자임스 에이/에스 활성부위 루프 영역에 추가적 아미노산 잔기를 가지는서브그룹 ｉ-ｓ1과 ｉ-ｓ2의 서브틸라제 효소
JP4611530B2 (ja) * 1998-12-18 2011-01-12 ノボザイムス アクティーゼルスカブ 活性部位ループ領域中に追加のアミノ酸残基を有するサブチラーゼ酵素サブグループｉ−ｓ１及びｉ−ｓ２
JP4768128B2 (ja) * 1998-12-18 2011-09-07 ノボザイムス アクティーゼルスカブ 活性部位ループ領域中に追加のアミノ酸残基を有するサブチラーゼ酵素サブグループｉ−ｓ１及びｉ−ｓ２
BRPI9916352B1 (pt) * 1998-12-18 2016-04-19 Novozymes As enzima de subtilase isolada dos subgrupos i-s1 e i-s2, subtilase, seqüência isolada de dna, vetor de expressão, célula hospedeira microbiana, método para produzir uma subtilase ou uma variante de subtilase, composição, e, uso de uma subtilase ou de uma variante de subtilase ou de uma composição de enzima
BRPI9916351B1 (pt) * 1998-12-18 2016-04-12 Novozymes As enzima de subtilase isolada, composição, e, uso de uma enzima subtilase isolada ou de uma composição de enzima
CN1334869A (zh) * 1998-12-18 2002-02-06 诺沃奇梅兹有限公司 在活性位点环区中具有额外氨基酸残基的i－s1和i－s2亚组枯草杆菌酶
JP4647788B2 (ja) * 1998-12-18 2011-03-09 ノボザイムス アクティーゼルスカブ 活性部位ループ領域中に追加のアミノ酸残基を有するサブチラーゼ酵素サブグループｉ−ｓ１及びｉ−ｓ２
DE10153792A1 (de) * 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
DE10260903A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Neue Perhydrolasen
US7294499B2 (en) * 2003-01-30 2007-11-13 Novozymes A/S Subtilases
DE102004029475A1 (de) * 2004-06-18 2006-01-26 Henkel Kgaa Neues enzymatisches Bleichsystem
DE102007044415A1 (de) 2007-09-17 2009-03-19 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen
JP5412523B2 (ja) * 2008-11-11 2014-02-12 ダニスコ・ユーエス・インク スブチリシン変異体を含有する組成物と使用法
RU2733987C2 (ru) * 2015-05-13 2020-10-09 ДАНИСКО ЮЭс ИНК. Варианты протеазы клады aprl и их применения
DE102016204814A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Verbesserte Reinigungsleistung an Protein sensitiven Anschmutzungen
DE102016204815A1 (de) 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Proteasen mit verbesserte Enzymstabilität in Waschmittel
DE102017215629A1 (de) 2017-09-05 2019-03-07 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasevarianten III
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5310675A (en) * 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US5972682A (en) * 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US5346823A (en) * 1984-05-29 1994-09-13 Genencor, Inc. Subtilisin modifications to enhance oxidative stability
US5371008A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5185258A (en) * 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
US5700676A (en) * 1984-05-29 1997-12-23 Genencor International Inc. Modified subtilisins having amino acid alterations
US5155033A (en) * 1989-01-06 1992-10-13 Genencor, Inc. Subtilisins modified at position 225 resulting in a shift in catalytic activity
US5371190A (en) * 1984-05-29 1994-12-06 Genencor International, Inc. Substrate assisted catalysis
US5182204A (en) * 1984-05-29 1993-01-26 Genencor International, Inc. Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors
WO1987004461A1 (en) 1986-01-15 1987-07-30 Amgen THERMALLY STABLE AND pH STABLE SUBTILISIN ANALOGS AND METHOD FOR PRODUCTION THEREOF
US4908773A (en) 1987-04-06 1990-03-13 Genex Corporation Computer designed stabilized proteins and method for producing same
US5013657A (en) 1988-04-12 1991-05-07 Bryan Philip N Subtilisin mutations
US4990452A (en) * 1986-02-12 1991-02-05 Genex Corporation Combining mutations for stabilization of subtilisin
US4980288A (en) 1986-02-12 1990-12-25 Genex Corporation Subtilisin with increased thermal stability
JPS63502959A (ja) 1986-02-12 1988-11-02 ジェネックス、コ−ポレ−ション 突然変異誘発及びスクリ−ニング方法並びに生成物
US5240632A (en) * 1986-03-26 1993-08-31 Amway Corporation Machine dishwasher water spot control composition
IE65767B1 (en) * 1986-04-30 1995-11-15 Genencor Int Non-human carbonyl hydrolase mutants DNA sequences and vectors encoding same and hosts transformed with said vectors
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
JP3026567B2 (ja) * 1987-02-27 2000-03-27 ジェネンコー インターナショナル インコーポレイテッド 分子のクローニング及びタンパク分解酵素をコードする遺伝子の発現
ATE184316T1 (de) * 1987-04-06 1999-09-15 Novo Nordisk As Regelung von elektrostatischen interaktionen an metallionen-bindungsstellen zur stabilisierung von proteinen
US5260207A (en) * 1987-04-06 1993-11-09 Enzon Labs Inc. Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
CN1056187C (zh) * 1988-02-11 2000-09-06 金克克国际有限公司 新的蛋白水解酶及其在洗涤剂中的应用
US5324653A (en) * 1988-02-11 1994-06-28 Gist-Brocades N.V. Recombinant genetic means for the production of serine protease muteins
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
US5116741A (en) 1988-04-12 1992-05-26 Genex Corporation Biosynthetic uses of thermostable proteases
US5246849A (en) 1988-04-12 1993-09-21 Enzon, Inc. Thermally stable serine proteases
US5118623A (en) * 1988-05-27 1992-06-02 Solvay Enzymes, Inc. Bleach stable enzymes
WO1990014420A1 (en) 1989-05-17 1990-11-29 Amgen Inc. Multiply mutated subtilisins
JPH04500384A (ja) 1989-06-26 1992-01-23 ユニリーバー・ナームローゼ・ベンノートシヤープ 酵素洗剤組成物
EP0405901B1 (en) 1989-06-26 2004-09-01 Unilever Plc Enzymatic detergent compositions
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DK316989D0 (da) 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US5352603A (en) * 1989-08-31 1994-10-04 Kali-Chemie Ag Highly alkaline proteases
US6271012B1 (en) * 1989-10-11 2001-08-07 Genencor International, Inc. Protease muteins and their use in detergents
DE4009534A1 (de) * 1990-03-24 1991-09-26 Henkel Kgaa Fluessiges handreinigungsmittel
DK97190D0 (da) * 1990-04-19 1990-04-19 Novo Nordisk As Oxidationsstabile detergentenzymer
US5629173A (en) * 1990-08-09 1997-05-13 Genentech, Inc. Methods of use of serine protease variants having peptide ligase activity
WO1992002615A1 (en) * 1990-08-09 1992-02-20 Genentech, Inc. Serine protease variants having peptide ligase activity
DK271490D0 (da) * 1990-11-14 1990-11-14 Novo Nordisk As Detergentkomposition
US5482849A (en) * 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
ES2110488T3 (es) 1990-12-21 1998-02-16 Novo Nordisk As Mutantes enzimaticos con un bajo grado de variacion de la carga molecular en un intervalo de ph.
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
EP0995801A1 (de) * 1991-07-27 2000-04-26 Genencor International GmbH Verfahren zur Verbesserung des Stabilität von Enzymen und stabilisierte Enzyme
US5275945A (en) * 1991-10-08 1994-01-04 Vista Chemical Company Alkaline proteases stable in heavy-duty detergent liquids
PL178045B1 (pl) 1992-07-17 2000-02-29 Genencor Int Mutant proteazy do stosowania w detergentach, sekwencja DNA kodująca mutanta proteazy, sposób otrzymywania mutanta proteazy oraz kompozycja detergentowa
US5567601A (en) * 1993-06-01 1996-10-22 University Of Maryland Subtilisin mutants lacking a primary calcium binding site
US5470733A (en) * 1993-06-01 1995-11-28 University Of Maryland Calcium free subtilisin mutants
WO1995007991A2 (en) 1993-09-15 1995-03-23 The Procter & Gamble Company Subtilisin bpn' variants with decreased adsorption and increased hydrolysis
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
DE69432954T2 (de) * 1993-10-14 2004-04-22 The Procter & Gamble Company, Cincinnati Proteasen enthaltende bleichmittelzusammensetzungen
AU8079794A (en) * 1993-10-14 1995-05-04 Procter & Gamble Company, The Protease-containing cleaning compositions
ES2364774T3 (es) * 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US5780285A (en) * 1995-03-03 1998-07-14 Genentech, Inc. Subtilisin variants capable of cleaving substrates containing dibasic residues

Also Published As

Publication number Publication date
CN1183119A (zh) 1998-05-27
HUP9800765A3 (en) 2001-01-29
EP0813596A2 (en) 1997-12-29
CA2214348C (en) 2001-10-30
MA23818A1 (fr) 1996-10-01
US6455295B1 (en) 2002-09-24
CA2214348A1 (en) 1996-09-19
CZ279397A3 (en) 1997-11-12
ZA961631B (en) 1996-09-06
MX9706851A (es) 1997-11-29
HUP9800765A2 (hu) 1998-07-28
AU4868896A (en) 1996-10-02
IL117266A0 (en) 1996-06-18
JPH11501812A (ja) 1999-02-16
WO1996028566A3 (en) 1997-07-10
WO1996028566A2 (en) 1996-09-19

Similar Documents

Publication Publication Date Title
BR9607356A (pt) Variantes de subtilisina carlsberg tendo adsorção diminuída e hidrólise aumentada
BR9507605A (pt) Variantes de subtilisina 309 tendo adsorção diminuida e hidrólise aumentada
BR9507597A (pt) Variantes de subtilisina bpn tendo adsorção diminuída e hidrólise aumentada
BR9607677A (pt) Variantes de porteinase k tendo adsorção reduzida e hidrolise aumentada
DE69728434D1 (de) Ankoppelvorrichtung und flaschen
DE69627188D1 (de) Brille und brillenfassung
ZA952220B (en) Bpn' variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
AU5646596A (en) Subtilisin variants
BR9607758A (pt) Variantes de subtilisina dy tendo absorção diminuída e hidrólise aumentada
ID19147A (id) Ksilanase dan pemakaiannya
BR9607756A (pt) Variantes termitase possuindo adsorção diminuida e hidrólise aumentada
EP0817817A4 (en) ICE-PREGNATING MOLECULES AND THEIR USE
GB9504030D0 (en) Break and stop lighting sensor
HUP9801330A3 (en) Novel pka-binding proteins and uses thereof
AU4984896A (en) Psychrophilic protease and psychrophilic bacteria
NO951448D0 (no) Kontaktering mellom betjenings- og visningsorganer
IL117164A0 (en) Cold-active protease and cold-active bacteria
PL324340A1 (en) Novel quinoxalinophosphonic and quinoxalinoalkanophosphonic acids
ATE311440T1 (de) Bacillus-proteasen
ATE313624T1 (de) Bacillus proteasen
KR960033565U (ko) 지압 및 쑥뜸 겸용 지압구
AU2745695A (en) Schistosoma protein and uses thereof
BR9504641A (pt) Prótese puntiforme ou de contato minimo
KR970006491A (ko) 트롬빈 유사 단백질 분해효소 및 그의 제조방법
ITRM950248V0 (it) Prova e riprova

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 8/66 (2006.01), A61Q 11/00 (2006.0