BR112014031424A2 - tratamento de células pluripotentes - Google Patents
tratamento de células pluripotentesInfo
- Publication number
- BR112014031424A2 BR112014031424A2 BR112014031424A BR112014031424A BR112014031424A2 BR 112014031424 A2 BR112014031424 A2 BR 112014031424A2 BR 112014031424 A BR112014031424 A BR 112014031424A BR 112014031424 A BR112014031424 A BR 112014031424A BR 112014031424 A2 BR112014031424 A2 BR 112014031424A2
- Authority
- BR
- Brazil
- Prior art keywords
- pluripotent cell
- pluripotent cells
- cell treatment
- treating
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/105—Insulin-like growth factors [IGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Abstract
resumo patente de invenção: "tratamento de células pluripotentes". a presente invenção refere-se a métodos para tratar células pluripotentes, através do qual as células pluripotentes podem ser eficientemente expandidas em cultura e diferenciadas pelo tratamento de células pluripotentes com um inibidor de atividade da enzima gsk-3b.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261741776P | 2012-06-14 | 2012-06-14 | |
PCT/US2013/045617 WO2013192005A2 (en) | 2012-06-14 | 2013-06-13 | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112014031424A2 true BR112014031424A2 (pt) | 2017-06-27 |
Family
ID=49756254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014031424A BR112014031424A2 (pt) | 2012-06-14 | 2013-06-13 | tratamento de células pluripotentes |
Country Status (14)
Country | Link |
---|---|
US (1) | US20130337564A1 (pt) |
EP (1) | EP2861723A4 (pt) |
JP (1) | JP2015519085A (pt) |
KR (1) | KR20150030709A (pt) |
CN (1) | CN104603262A (pt) |
AR (1) | AR091457A1 (pt) |
BR (1) | BR112014031424A2 (pt) |
CA (1) | CA2876671A1 (pt) |
MX (1) | MX2014015419A (pt) |
PH (1) | PH12014502748A1 (pt) |
RU (1) | RU2015100900A (pt) |
SG (1) | SG11201408150UA (pt) |
WO (1) | WO2013192005A2 (pt) |
ZA (1) | ZA201500224B (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA034922B1 (ru) | 2013-03-15 | 2020-04-07 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
RU2016100219A (ru) | 2013-06-11 | 2017-07-17 | Президент Энд Феллоус Оф Гарвард Колледж | КЛЕТКИ SC-β И КОМПОЗИЦИИ, И СПОСОБЫ ДЛЯ ИХ СОЗДАНИЯ |
EA202092627A1 (ru) | 2013-11-18 | 2021-09-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
WO2016100930A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Methods for generating stem cell-derived b cells and methods of use thereof |
EP3234110B1 (en) | 2014-12-18 | 2024-02-28 | President and Fellows of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF |
US20190359941A1 (en) * | 2016-08-18 | 2019-11-28 | National University Of Singapore | Substituted azole derivatives for generation, proliferation and differentiation of hematopoietic stem and progenitor cells |
KR102516844B1 (ko) * | 2016-11-16 | 2023-04-04 | 시나타 세라퓨틱스 엘티디 | 만능성 줄기 세포 분석 |
US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
US11433148B2 (en) | 2017-05-05 | 2022-09-06 | Centre For Probe Development And Commercialization | IGF-1R monoclonal antibodies and uses thereof |
US10093741B1 (en) | 2017-05-05 | 2018-10-09 | Fusion Pharmaceuticals Inc. | IGF-1R monoclonal antibodies and uses thereof |
EA201992595A1 (ru) | 2017-05-05 | 2020-04-21 | Фьюжн Фармасьютикалс Инк. | Усиление фармакокинетики бифункциональных хелатов и их применения |
KR101966523B1 (ko) * | 2017-05-29 | 2019-04-05 | 차의과학대학교 산학협력단 | 오가노이드 배양을 위한 조성물 및 방법 |
US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
WO2019099725A1 (en) | 2017-11-15 | 2019-05-23 | Semma Therapeutics, Inc. | Islet cell manufacturing compositions and methods of use |
JP2021526806A (ja) * | 2018-06-08 | 2021-10-11 | ノバルティス アーゲー | 薬物製品の効力を測定するための細胞ベースアッセイ |
WO2020033879A1 (en) | 2018-08-10 | 2020-02-13 | Semma Therapeutics, Inc. | Stem cell derived islet differentiation |
US20200080107A1 (en) | 2018-09-07 | 2020-03-12 | Crispr Therapeutics Ag | Universal donor cells |
JP2022547505A (ja) | 2019-09-05 | 2022-11-14 | クリスパー セラピューティクス アクチェンゲゼルシャフト | ユニバーサルドナー細胞 |
CN114364791A (zh) | 2019-09-05 | 2022-04-15 | 克里斯珀医疗股份公司 | 通用供体细胞 |
EP4271796A1 (en) | 2020-12-31 | 2023-11-08 | CRISPR Therapeutics AG | Universal donor cells |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060030042A1 (en) * | 2003-12-19 | 2006-02-09 | Ali Brivanlou | Maintenance of embryonic stem cells by the GSK-3 inhibitor 6-bromoindirubin-3'-oxime |
WO2007030870A1 (en) * | 2005-09-12 | 2007-03-22 | Es Cell International Pte Ltd | Cardiomyocyte production |
US8741643B2 (en) * | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
US8623648B2 (en) * | 2008-04-24 | 2014-01-07 | Janssen Biotech, Inc. | Treatment of pluripotent cells |
US7939322B2 (en) * | 2008-04-24 | 2011-05-10 | Centocor Ortho Biotech Inc. | Cells expressing pluripotency markers and expressing markers characteristic of the definitive endoderm |
-
2013
- 2013-06-13 RU RU2015100900A patent/RU2015100900A/ru not_active Application Discontinuation
- 2013-06-13 BR BR112014031424A patent/BR112014031424A2/pt not_active IP Right Cessation
- 2013-06-13 CN CN201380031065.6A patent/CN104603262A/zh active Pending
- 2013-06-13 CA CA2876671A patent/CA2876671A1/en not_active Abandoned
- 2013-06-13 MX MX2014015419A patent/MX2014015419A/es unknown
- 2013-06-13 KR KR1020157000636A patent/KR20150030709A/ko not_active Application Discontinuation
- 2013-06-13 EP EP13806895.2A patent/EP2861723A4/en not_active Withdrawn
- 2013-06-13 SG SG11201408150UA patent/SG11201408150UA/en unknown
- 2013-06-13 US US13/917,109 patent/US20130337564A1/en not_active Abandoned
- 2013-06-13 JP JP2015517419A patent/JP2015519085A/ja active Pending
- 2013-06-13 WO PCT/US2013/045617 patent/WO2013192005A2/en active Application Filing
- 2013-06-14 AR ARP130102110 patent/AR091457A1/es unknown
-
2014
- 2014-12-09 PH PH12014502748A patent/PH12014502748A1/en unknown
-
2015
- 2015-01-13 ZA ZA2015/00224A patent/ZA201500224B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2861723A2 (en) | 2015-04-22 |
PH12014502748A1 (en) | 2015-02-02 |
SG11201408150UA (en) | 2015-01-29 |
MX2014015419A (es) | 2015-07-14 |
ZA201500224B (en) | 2017-09-27 |
RU2015100900A (ru) | 2016-08-10 |
CN104603262A (zh) | 2015-05-06 |
CA2876671A1 (en) | 2013-12-27 |
WO2013192005A2 (en) | 2013-12-27 |
AR091457A1 (es) | 2015-02-04 |
KR20150030709A (ko) | 2015-03-20 |
JP2015519085A (ja) | 2015-07-09 |
WO2013192005A3 (en) | 2014-03-13 |
US20130337564A1 (en) | 2013-12-19 |
EP2861723A4 (en) | 2016-01-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |