BR112014027783A2 - diferenciação de células-tronco embrionárias humanas em endoderma pancreático - Google Patents

diferenciação de células-tronco embrionárias humanas em endoderma pancreático

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Publication number
BR112014027783A2
BR112014027783A2 BR112014027783A BR112014027783A BR112014027783A2 BR 112014027783 A2 BR112014027783 A2 BR 112014027783A2 BR 112014027783 A BR112014027783 A BR 112014027783A BR 112014027783 A BR112014027783 A BR 112014027783A BR 112014027783 A2 BR112014027783 A2 BR 112014027783A2
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BR
Brazil
Prior art keywords
stem cells
differentiation
pancreatic endoderm
human embryonic
embryonic stem
Prior art date
Application number
BR112014027783A
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English (en)
Inventor
Rezania Alireza
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of BR112014027783A2 publication Critical patent/BR112014027783A2/pt

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

Abstract

resumo patente de invenção: "diferenciação de células-tronco embrionárias humanas em endoderma pancreático". a presente invenção refere-se a métodos para promover a diferenciação de células-tronco pluripotentes. em particular, a presente invenção refere-se a métodos para produzir uma população de células de endoderma pancreático, em que a densidade de semeadura inicial de células pluripotentes não diferenciadas é definida.
BR112014027783A 2012-05-07 2013-05-07 diferenciação de células-tronco embrionárias humanas em endoderma pancreático BR112014027783A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261643684P 2012-05-07 2012-05-07
PCT/US2013/039940 WO2013169769A1 (en) 2012-05-07 2013-05-07 Differentiation of human embryonic stem cells into pancreatic endoderm

Publications (1)

Publication Number Publication Date
BR112014027783A2 true BR112014027783A2 (pt) 2017-06-27

Family

ID=49551213

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014027783A BR112014027783A2 (pt) 2012-05-07 2013-05-07 diferenciação de células-tronco embrionárias humanas em endoderma pancreático

Country Status (17)

Country Link
US (1) US20140162359A1 (pt)
EP (1) EP2847319A4 (pt)
JP (1) JP6450674B2 (pt)
KR (1) KR20150014478A (pt)
CN (1) CN104284977A (pt)
AR (1) AR090970A1 (pt)
AU (1) AU2013259706A1 (pt)
BR (1) BR112014027783A2 (pt)
CA (1) CA2872770A1 (pt)
HK (1) HK1207885A1 (pt)
IL (1) IL235132A0 (pt)
IN (1) IN2014DN08561A (pt)
MX (1) MX2014013524A (pt)
PH (1) PH12014502686A1 (pt)
RU (1) RU2668814C2 (pt)
SG (1) SG11201406884SA (pt)
WO (1) WO2013169769A1 (pt)

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CN107614678B (zh) 2014-12-18 2021-04-30 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
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US10443042B2 (en) 2014-12-18 2019-10-15 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
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Also Published As

Publication number Publication date
JP6450674B2 (ja) 2019-01-09
AU2013259706A1 (en) 2014-10-30
RU2668814C2 (ru) 2018-10-02
EP2847319A1 (en) 2015-03-18
CA2872770A1 (en) 2013-11-14
WO2013169769A1 (en) 2013-11-14
IN2014DN08561A (pt) 2015-05-22
HK1207885A1 (en) 2016-02-12
US20140162359A1 (en) 2014-06-12
JP2015516161A (ja) 2015-06-11
CN104284977A (zh) 2015-01-14
EP2847319A4 (en) 2015-12-16
KR20150014478A (ko) 2015-02-06
SG11201406884SA (en) 2014-11-27
MX2014013524A (es) 2015-02-10
RU2014149185A (ru) 2016-06-27
IL235132A0 (en) 2014-12-31
PH12014502686A1 (en) 2015-01-26
AR090970A1 (es) 2014-12-17

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Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

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