BR112013022208A2 - Ensaios baseados em investigação celular e usos destes - Google Patents
Ensaios baseados em investigação celular e usos destesInfo
- Publication number
- BR112013022208A2 BR112013022208A2 BR112013022208A BR112013022208A BR112013022208A2 BR 112013022208 A2 BR112013022208 A2 BR 112013022208A2 BR 112013022208 A BR112013022208 A BR 112013022208A BR 112013022208 A BR112013022208 A BR 112013022208A BR 112013022208 A2 BR112013022208 A2 BR 112013022208A2
- Authority
- BR
- Brazil
- Prior art keywords
- biological system
- data
- based assays
- cellular
- model
- Prior art date
Links
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
- G16B5/20—Probabilistic models
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Physiology (AREA)
- Genetics & Genomics (AREA)
- Probability & Statistics with Applications (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Mobile Radio Communication Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
ensaios baseados em investigação celular e usos destes. é descrito neste pedido é uma tecnologia de plataforma de descoberta para analisar um sistema ou processo biológico (por exemplo, uma condição de doença, como câncer) através da construção de modelos. em particular, é descrito neste pedido um método para identificar um modulador de um sistema biológico pelo estabelecimento de um modelo para o sistema biológico, obtendo um segundo conjunto de dados do modelo para o sistema biológico, e geração de uma rede de relações causais consenso entre os níveis de expressão da pluralidade de genes e a atividade funcional ou resposta celular baseada somente no primeiro conjunto de dados e no segundo conjunto de dados usando um dispositivo computacional programado.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161448587P | 2011-03-02 | 2011-03-02 | |
US201261593848P | 2012-02-01 | 2012-02-01 | |
PCT/US2012/027615 WO2012119129A1 (en) | 2011-03-02 | 2012-03-02 | Interrogatory cell-based assays and uses thereof |
Publications (1)
Publication Number | Publication Date |
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BR112013022208A2 true BR112013022208A2 (pt) | 2022-03-08 |
Family
ID=46758320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013022208A BR112013022208A2 (pt) | 2011-03-02 | 2012-03-02 | Ensaios baseados em investigação celular e usos destes |
Country Status (20)
Country | Link |
---|---|
US (3) | US9886545B2 (pt) |
EP (1) | EP2680925B1 (pt) |
JP (2) | JP6105491B2 (pt) |
KR (1) | KR102071081B1 (pt) |
CN (2) | CN103501859B (pt) |
AU (2) | AU2012223136B2 (pt) |
BR (1) | BR112013022208A2 (pt) |
CA (1) | CA2828972C (pt) |
CL (2) | CL2013002526A1 (pt) |
CO (1) | CO6801640A2 (pt) |
EA (1) | EA201391245A1 (pt) |
ES (1) | ES2777894T3 (pt) |
IL (2) | IL228096B (pt) |
MX (1) | MX358408B (pt) |
MY (2) | MY164530A (pt) |
PE (2) | PE20180776A1 (pt) |
PH (2) | PH12017502073A1 (pt) |
SG (2) | SG193006A1 (pt) |
WO (1) | WO2012119129A1 (pt) |
ZA (1) | ZA201306453B (pt) |
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US20150019189A1 (en) * | 2013-07-01 | 2015-01-15 | Counterpoint Health Solutions, Inc. | Systems biology approach to therapy |
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