BR112013022208A2 - Ensaios baseados em investigação celular e usos destes - Google Patents

Ensaios baseados em investigação celular e usos destes

Info

Publication number
BR112013022208A2
BR112013022208A2 BR112013022208A BR112013022208A BR112013022208A2 BR 112013022208 A2 BR112013022208 A2 BR 112013022208A2 BR 112013022208 A BR112013022208 A BR 112013022208A BR 112013022208 A BR112013022208 A BR 112013022208A BR 112013022208 A2 BR112013022208 A2 BR 112013022208A2
Authority
BR
Brazil
Prior art keywords
biological system
data
based assays
cellular
model
Prior art date
Application number
BR112013022208A
Other languages
English (en)
Inventor
Rajin Narain Niven
Rangaprasad Sarangarajan
K Vishnudas Vivek
Original Assignee
Berg Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berg Llc filed Critical Berg Llc
Publication of BR112013022208A2 publication Critical patent/BR112013022208A2/pt

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/20—Probabilistic models
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Physiology (AREA)
  • Genetics & Genomics (AREA)
  • Probability & Statistics with Applications (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

ensaios baseados em investigação celular e usos destes. é descrito neste pedido é uma tecnologia de plataforma de descoberta para analisar um sistema ou processo biológico (por exemplo, uma condição de doença, como câncer) através da construção de modelos. em particular, é descrito neste pedido um método para identificar um modulador de um sistema biológico pelo estabelecimento de um modelo para o sistema biológico, obtendo um segundo conjunto de dados do modelo para o sistema biológico, e geração de uma rede de relações causais consenso entre os níveis de expressão da pluralidade de genes e a atividade funcional ou resposta celular baseada somente no primeiro conjunto de dados e no segundo conjunto de dados usando um dispositivo computacional programado.
BR112013022208A 2011-03-02 2012-03-02 Ensaios baseados em investigação celular e usos destes BR112013022208A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161448587P 2011-03-02 2011-03-02
US201261593848P 2012-02-01 2012-02-01
PCT/US2012/027615 WO2012119129A1 (en) 2011-03-02 2012-03-02 Interrogatory cell-based assays and uses thereof

Publications (1)

Publication Number Publication Date
BR112013022208A2 true BR112013022208A2 (pt) 2022-03-08

Family

ID=46758320

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013022208A BR112013022208A2 (pt) 2011-03-02 2012-03-02 Ensaios baseados em investigação celular e usos destes

Country Status (20)

Country Link
US (3) US9886545B2 (pt)
EP (1) EP2680925B1 (pt)
JP (2) JP6105491B2 (pt)
KR (1) KR102071081B1 (pt)
CN (2) CN103501859B (pt)
AU (2) AU2012223136B2 (pt)
BR (1) BR112013022208A2 (pt)
CA (1) CA2828972C (pt)
CL (2) CL2013002526A1 (pt)
CO (1) CO6801640A2 (pt)
EA (1) EA201391245A1 (pt)
ES (1) ES2777894T3 (pt)
IL (2) IL228096B (pt)
MX (1) MX358408B (pt)
MY (2) MY164530A (pt)
PE (2) PE20180776A1 (pt)
PH (2) PH12017502073A1 (pt)
SG (2) SG193006A1 (pt)
WO (1) WO2012119129A1 (pt)
ZA (1) ZA201306453B (pt)

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Also Published As

Publication number Publication date
MX358408B (es) 2018-08-20
CN107273712B (zh) 2021-12-03
NZ712105A (en) 2017-05-26
CL2013002526A1 (es) 2014-04-25
US20240062844A1 (en) 2024-02-22
EP2680925A1 (en) 2014-01-08
US20180260515A1 (en) 2018-09-13
AU2017202977B2 (en) 2019-09-19
CL2020002805A1 (es) 2021-04-30
JP2014512520A (ja) 2014-05-22
WO2012119129A1 (en) 2012-09-07
MY181093A (en) 2020-12-17
EP2680925B1 (en) 2019-11-20
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US20120258874A1 (en) 2012-10-11
AU2012223136B2 (en) 2017-05-25
CN107273712A (zh) 2017-10-20
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EP2680925A4 (en) 2014-12-31
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