BG107203A - Състав с активиращо действие - Google Patents

Състав с активиращо действие Download PDF

Info

Publication number
BG107203A
BG107203A BG107203A BG10720302A BG107203A BG 107203 A BG107203 A BG 107203A BG 107203 A BG107203 A BG 107203A BG 10720302 A BG10720302 A BG 10720302A BG 107203 A BG107203 A BG 107203A
Authority
BG
Bulgaria
Prior art keywords
hematopoietic
defibrotide
csf
activating
progenitor cells
Prior art date
Application number
BG107203A
Other languages
Bulgarian (bg)
English (en)
Inventor
Laura Ferro
Roberto Porta
Massimo Iacobelli
Alessandro GIANNI
Carmelo STELLA
Original Assignee
Gentium Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentium Spa filed Critical Gentium Spa
Publication of BG107203A publication Critical patent/BG107203A/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
BG107203A 2000-04-18 2002-10-17 Състав с активиращо действие BG107203A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00830293A EP1147777A1 (en) 2000-04-18 2000-04-18 Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
PCT/EP2001/004105 WO2001078761A2 (en) 2000-04-18 2001-04-10 Mixture of defibrotide and g-csf ant its use for activating haematopoietic progenitors

Publications (1)

Publication Number Publication Date
BG107203A true BG107203A (bg) 2003-05-30

Family

ID=8175292

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107203A BG107203A (bg) 2000-04-18 2002-10-17 Състав с активиращо действие

Country Status (31)

Country Link
US (1) US20040131588A1 (el)
EP (3) EP1147777A1 (el)
JP (1) JP5205668B2 (el)
KR (1) KR100849491B1 (el)
CN (1) CN1183962C (el)
AT (2) ATE310532T1 (el)
AU (2) AU5832201A (el)
BG (1) BG107203A (el)
CA (1) CA2406179C (el)
CY (1) CY1104971T1 (el)
CZ (1) CZ20023426A3 (el)
DE (2) DE60115222T2 (el)
DK (2) DK1621207T3 (el)
EE (1) EE200200596A (el)
ES (2) ES2252227T3 (el)
HR (1) HRP20020835A2 (el)
HU (1) HUP0300560A3 (el)
IL (1) IL152328A (el)
IS (1) IS2171B (el)
MX (1) MXPA02010346A (el)
NO (1) NO20024988L (el)
NZ (1) NZ522016A (el)
PL (1) PL358100A1 (el)
PT (1) PT1621207E (el)
RO (1) RO121006B1 (el)
RU (1) RU2248216C2 (el)
SI (1) SI21079B (el)
SK (1) SK14892002A3 (el)
UA (1) UA73566C2 (el)
WO (1) WO2001078761A2 (el)
ZA (1) ZA200208413B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771663B2 (en) 2000-04-18 2014-07-08 Gentium Spa Formulation having mobilising activity
JP2007535479A (ja) 2003-08-13 2007-12-06 チルドレンズ ホスピタル メディカル センター GTPaseを調節するためのキメラペプチド
EP1656156A2 (en) 2003-08-13 2006-05-17 Children's Hospital Medical Center Mobilization of hematopoietic cells
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
RU2376985C1 (ru) * 2008-07-17 2009-12-27 Владислав Николаевич Ласкавый Средство для активации стволовых клеток
CN107007617A (zh) 2010-11-12 2017-08-04 真蒂奥姆责任有限公司 去纤维蛋白多核苷酸用于预防和/或治疗移植物抗宿主病(gvhd)
CN104619857A (zh) 2012-06-22 2015-05-13 真蒂奥姆有限公司 用于测定去纤维蛋白多核苷酸的生物活性的基于优球蛋白的方法
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
CN106567694A (zh) * 2016-11-14 2017-04-19 北京国泰通源技术有限公司 智能控水短节
RU2758487C2 (ru) * 2018-01-12 2021-10-28 Селлмиг Биолабс Инк. Способы получения цитокапсул и цитокапсулярных трубок
JP7270762B2 (ja) 2019-11-13 2023-05-10 富士フイルム株式会社 加飾フィルム、成型物、及び電子デバイス

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2154279A1 (de) 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1043823B (it) 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
US3899481A (en) 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1206341B (it) 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
US4694134A (en) 1985-05-28 1987-09-15 Ajax Magnethermic Corporation Apparatus for overheating edges of skelp for the production of compression welded pipe
US5223609A (en) 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1190313B (it) 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
JP2907447B2 (ja) * 1988-08-24 1999-06-21 中外製薬株式会社 抗血栓剤
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
JP3021906B2 (ja) * 1992-01-28 2000-03-15 松下電器産業株式会社 電動調理機
JPH08127539A (ja) * 1994-10-31 1996-05-21 Ajinomoto Co Inc ヒトil−11を含有する末梢血幹細胞増加剤
AU3994095A (en) * 1994-11-30 1996-06-19 Chugai Seiyaku Kabushiki Kaisha Thrombocytotic factor
WO1998001151A1 (fr) * 1996-07-10 1998-01-15 Meiji Milk Products Co., Ltd. Nouvelle utilisation de la famille mk comme facteur hematopoietique
AU1705599A (en) * 1997-11-26 1999-06-15 Allegheny University Of The Health Sciences Methods for mobilizing hematopoietic facilitating cells and hematopoietic stem cells into the peripheral blood
US6573372B2 (en) * 1999-01-07 2003-06-03 Heska Corporation Feline immunoglobulin E molecules and compositions there of

Also Published As

Publication number Publication date
NO20024988L (no) 2002-12-02
SK14892002A3 (sk) 2003-06-03
ES2335776T3 (es) 2010-04-05
CZ20023426A3 (cs) 2003-05-14
ZA200208413B (en) 2003-10-17
PT1621207E (pt) 2009-12-28
KR20030010603A (ko) 2003-02-05
SI21079A (sl) 2003-06-30
RU2002130719A (ru) 2004-03-27
MXPA02010346A (es) 2004-09-06
AU2001258322B2 (en) 2006-03-16
EP1276497A2 (en) 2003-01-22
SI21079B (sl) 2006-08-31
UA73566C2 (en) 2005-08-15
DE60115222D1 (de) 2005-12-29
RU2248216C2 (ru) 2005-03-20
NO20024988D0 (no) 2002-10-16
IS6581A (is) 2002-10-14
CN1434719A (zh) 2003-08-06
EP1621207A2 (en) 2006-02-01
DE60140015D1 (de) 2009-11-05
CY1104971T1 (el) 2010-03-03
EE200200596A (et) 2004-04-15
NZ522016A (en) 2004-10-29
DK1621207T3 (da) 2010-02-01
IS2171B (is) 2006-11-15
KR100849491B1 (ko) 2008-07-31
CA2406179A1 (en) 2001-10-25
HUP0300560A3 (en) 2005-07-28
IL152328A (en) 2009-12-24
EP1276497B1 (en) 2005-11-23
ES2252227T3 (es) 2006-05-16
JP5205668B2 (ja) 2013-06-05
EP1147777A1 (en) 2001-10-24
JP2004500437A (ja) 2004-01-08
US20040131588A1 (en) 2004-07-08
RO121006B1 (ro) 2006-11-30
HUP0300560A2 (hu) 2003-06-28
PL358100A1 (en) 2004-08-09
WO2001078761A2 (en) 2001-10-25
AU5832201A (en) 2001-10-30
ATE310532T1 (de) 2005-12-15
CN1183962C (zh) 2005-01-12
EP1621207B1 (en) 2009-09-23
DK1276497T3 (da) 2006-03-27
ATE443524T1 (de) 2009-10-15
HRP20020835A2 (en) 2005-10-31
WO2001078761A3 (en) 2002-01-24
DE60115222T2 (de) 2006-08-10
CA2406179C (en) 2012-03-27
IL152328A0 (en) 2003-05-29
EP1621207A3 (en) 2006-11-22

Similar Documents

Publication Publication Date Title
US9782429B2 (en) Formulation having mobilizing activity
Riches Macrophage involvement in wound repair, remodeling, and fibrosis
JP4727988B2 (ja) エリスロポエチンの使用
Steward et al. Recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) given as daily short infusions–a phase I dose-toxicity study
BG107203A (bg) Състав с активиращо действие
AU2001258322A1 (en) Formulation having mobilising activity
US7220407B2 (en) G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
CZ120298A3 (cs) Použití proteinu získaného z chemokinu savců
KR20190039145A (ko) 대체 면역요법으로서의 il-12의 용도
JP3501801B2 (ja) 組み換えコロニー刺激因子―1の使用
EP0800402A1 (en) Mobilisation of haematopoietic cells
KR101144687B1 (ko) G-csf 를 함유하는 선유아세포 동원제 및 창상 치료제
EP0661057A1 (en) Hematopoietic cell proliferation accelerator
CN115317473A (zh) 棕榈酰化抑制剂在制备外周血造血干/祖细胞动员药物中的用途
JP2010539136A (ja) 卒中発作を治療するためのg−csfの使用