CY1104971T1 - Παρασκευασμα αποϊνιδοτιδιου και g-csf και η χρηση του για να κινητοποιει αιμοποιητικους προγονους - Google Patents

Παρασκευασμα αποϊνιδοτιδιου και g-csf και η χρηση του για να κινητοποιει αιμοποιητικους προγονους

Info

Publication number
CY1104971T1
CY1104971T1 CY20061100179T CY061100179T CY1104971T1 CY 1104971 T1 CY1104971 T1 CY 1104971T1 CY 20061100179 T CY20061100179 T CY 20061100179T CY 061100179 T CY061100179 T CY 061100179T CY 1104971 T1 CY1104971 T1 CY 1104971T1
Authority
CY
Cyprus
Prior art keywords
csf
progenors
hemapopoietic
apoinidotide
stimulate
Prior art date
Application number
CY20061100179T
Other languages
English (en)
Inventor
Laura Ferro
Roberto Porta
Massimo Iacobelli
Alessandro Massimo Gianni
Carmelo Carlo Stella
Original Assignee
Gentium Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gentium Spa filed Critical Gentium Spa
Publication of CY1104971T1 publication Critical patent/CY1104971T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Δίνεται περιγραφή μιας μεθόδου αύξησης της ποσότητας βλαστικών κυττάρων και /ή αιμοποιητικών προγόνων στο περιφερειακό αίμα θηλαστικού η μέθοδος χαρακτηρίζεται από την χορήγηση αποϊνιδοτιδίου σε συνδυασμό ή σε χρονική αμεσότητα με τουλάχιστον έναν αιμοποιητικό παράγοντα, (κατά προτίμηση G-CSF) που έχει την ικανότητα να κινητοποιεί αιμοποιητικούς προγόνους.
CY20061100179T 2000-04-18 2006-02-08 Παρασκευασμα αποϊνιδοτιδιου και g-csf και η χρηση του για να κινητοποιει αιμοποιητικους προγονους CY1104971T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00830293A EP1147777A1 (en) 2000-04-18 2000-04-18 Combination of defibrotide and G-CSF and its use to activate haematopoietic progenitors
EP01931582A EP1276497B1 (en) 2000-04-18 2001-04-10 Mixture of defibrotide and g-csf and its use for activating haematopoietic progenitors
PCT/EP2001/004105 WO2001078761A2 (en) 2000-04-18 2001-04-10 Mixture of defibrotide and g-csf ant its use for activating haematopoietic progenitors

Publications (1)

Publication Number Publication Date
CY1104971T1 true CY1104971T1 (el) 2010-03-03

Family

ID=8175292

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061100179T CY1104971T1 (el) 2000-04-18 2006-02-08 Παρασκευασμα αποϊνιδοτιδιου και g-csf και η χρηση του για να κινητοποιει αιμοποιητικους προγονους

Country Status (31)

Country Link
US (1) US20040131588A1 (el)
EP (3) EP1147777A1 (el)
JP (1) JP5205668B2 (el)
KR (1) KR100849491B1 (el)
CN (1) CN1183962C (el)
AT (2) ATE443524T1 (el)
AU (2) AU5832201A (el)
BG (1) BG107203A (el)
CA (1) CA2406179C (el)
CY (1) CY1104971T1 (el)
CZ (1) CZ20023426A3 (el)
DE (2) DE60115222T2 (el)
DK (2) DK1621207T3 (el)
EE (1) EE200200596A (el)
ES (2) ES2252227T3 (el)
HR (1) HRP20020835A2 (el)
HU (1) HUP0300560A3 (el)
IL (1) IL152328A (el)
IS (1) IS2171B (el)
MX (1) MXPA02010346A (el)
NO (1) NO20024988L (el)
NZ (1) NZ522016A (el)
PL (1) PL358100A1 (el)
PT (1) PT1621207E (el)
RO (1) RO121006B1 (el)
RU (1) RU2248216C2 (el)
SI (1) SI21079B (el)
SK (1) SK14892002A3 (el)
UA (1) UA73566C2 (el)
WO (1) WO2001078761A2 (el)
ZA (1) ZA200208413B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771663B2 (en) 2000-04-18 2014-07-08 Gentium Spa Formulation having mobilising activity
US7417026B2 (en) 2003-08-13 2008-08-26 Children's Hospital Medical Center Mobilization of hematopoietic cells
JP2007535479A (ja) 2003-08-13 2007-12-06 チルドレンズ ホスピタル メディカル センター ＧＴＰａｓｅを調節するためのキメラペプチド
EP2103689A1 (en) * 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
RU2376985C1 (ru) * 2008-07-17 2009-12-27 Владислав Николаевич Ласкавый Средство для активации стволовых клеток
CN103260627A (zh) 2010-11-12 2013-08-21 真蒂奥姆有限公司 去纤维蛋白多核苷酸用于预防和/或治疗移植物抗宿主病(gvhd)
DK2864496T4 (da) 2012-06-22 2021-01-04 Gentium S R L Euglobulin-baseret fremgangsmåde til bestemmelse af den biologiske aktivitet af defibrotid
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
CN106567694A (zh) * 2016-11-14 2017-04-19 北京国泰通源技术有限公司 智能控水短节
EP3574103A4 (en) * 2018-01-12 2020-09-23 Cellmig Biolabs Inc. METHOD FOR GENERATING CYTOCAPSULES AND CYTOCAPSULA TUBE
WO2021095881A1 (ja) 2019-11-13 2021-05-20 富士フイルム株式会社 加飾フィルム、成型物、及び電子デバイス

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IT1043823B (it) 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
DE2154279A1 (de) 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
US3899481A (en) 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
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US4694134A (en) 1985-05-28 1987-09-15 Ajax Magnethermic Corporation Apparatus for overheating edges of skelp for the production of compression welded pipe
US5223609A (en) 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
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IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
JP2907447B2 (ja) * 1988-08-24 1999-06-21 中外製薬株式会社 抗血栓剤
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Also Published As

Publication number Publication date
EP1276497A2 (en) 2003-01-22
KR100849491B1 (ko) 2008-07-31
US20040131588A1 (en) 2004-07-08
SI21079A (sl) 2003-06-30
PL358100A1 (en) 2004-08-09
IL152328A0 (en) 2003-05-29
RU2248216C2 (ru) 2005-03-20
RU2002130719A (ru) 2004-03-27
EP1621207A2 (en) 2006-02-01
AU2001258322B2 (en) 2006-03-16
DK1621207T3 (da) 2010-02-01
IL152328A (en) 2009-12-24
NO20024988L (no) 2002-12-02
CA2406179A1 (en) 2001-10-25
NZ522016A (en) 2004-10-29
CN1183962C (zh) 2005-01-12
EP1621207A3 (en) 2006-11-22
EE200200596A (et) 2004-04-15
SK14892002A3 (sk) 2003-06-03
DE60115222D1 (de) 2005-12-29
JP2004500437A (ja) 2004-01-08
EP1621207B1 (en) 2009-09-23
KR20030010603A (ko) 2003-02-05
CA2406179C (en) 2012-03-27
DE60140015D1 (de) 2009-11-05
HUP0300560A3 (en) 2005-07-28
NO20024988D0 (no) 2002-10-16
HRP20020835A2 (en) 2005-10-31
BG107203A (bg) 2003-05-30
AU5832201A (en) 2001-10-30
HUP0300560A2 (hu) 2003-06-28
ATE310532T1 (de) 2005-12-15
IS2171B (is) 2006-11-15
EP1276497B1 (en) 2005-11-23
DE60115222T2 (de) 2006-08-10
WO2001078761A2 (en) 2001-10-25
CN1434719A (zh) 2003-08-06
JP5205668B2 (ja) 2013-06-05
WO2001078761A3 (en) 2002-01-24
SI21079B (sl) 2006-08-31
UA73566C2 (en) 2005-08-15
ES2335776T3 (es) 2010-04-05
ZA200208413B (en) 2003-10-17
IS6581A (is) 2002-10-14
PT1621207E (pt) 2009-12-28
EP1147777A1 (en) 2001-10-24
ATE443524T1 (de) 2009-10-15
RO121006B1 (ro) 2006-11-30
MXPA02010346A (es) 2004-09-06
DK1276497T3 (da) 2006-03-27
ES2252227T3 (es) 2006-05-16
CZ20023426A3 (cs) 2003-05-14

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