BE876155A - Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique - Google Patents

Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique

Info

Publication number: BE876155A
Authority: BE; Belgium
Prior art keywords: dimeres; therapeutic use; catharanthus; alkaloids; catharanthus alkaloids
Prior art date: 1978-05-15

Application number

BE1/9386A

Other languages

English (en)

Inventor

R A Conrad

K Gerzon

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-15

Filing date

1979-05-10

Publication date

1979-11-12

1979-05-10 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1979-11-12 Publication of BE876155A publication Critical patent/BE876155A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BE1/9386A 1978-05-15 1979-05-10 Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique BE876155A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/905,667 US4199504A (en)	1978-05-15	1978-05-15	Bridged cathranthus alkaloid dimers

Publications (1)

Publication Number	Publication Date
BE876155A true BE876155A (fr)	1979-11-12

Family

ID=25421234

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE1/9386A BE876155A (fr)	1978-05-15	1979-05-10	Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique

Country Status (21)

Country	Link
US (1)	US4199504A (fr)
EP (3)	EP0032756A3 (fr)
JP (1)	JPS54148798A (fr)
AU (1)	AU4691379A (fr)
BE (1)	BE876155A (fr)
CA (1)	CA1114816A (fr)
CS (1)	CS214792B2 (fr)
DD (3)	DD147543A5 (fr)
DK (1)	DK197579A (fr)
ES (3)	ES480560A1 (fr)
FI (1)	FI791519A (fr)
FR (2)	FR2435480A1 (fr)
GB (1)	GB2022080A (fr)
GR (1)	GR73047B (fr)
IL (1)	IL57434A0 (fr)
LU (1)	LU81254A1 (fr)
PH (3)	PH14999A (fr)
PL (2)	PL120896B1 (fr)
PT (1)	PT69589A (fr)
RO (1)	RO81682B (fr)
ZA (1)	ZA792271B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4362664A (en) *	1980-12-29	1982-12-07	Eli Lilly And Company	Vinblastine oxazolidinedione disulfides and related compounds
EP0123441B1 (fr) *	1983-03-30	1990-10-03	Lilly Industries Limited	Dérivés de vincaleukoblastine
WO2000006582A1 (fr) *	1998-07-31	2000-02-10	Goldsmith Seeds, Inc.	Alcaloides trimeres et polymeres
EP2289549A3 (fr)	1999-10-01	2011-06-15	Immunogen, Inc.	Des immunoconjugués pour le traitement des cancers.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR204004A1 (es) *	1973-04-02	1975-11-12	Lilly Co Eli	Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) *	1975-01-09	1980-03-31	Lilly Co Eli	Amides of vincadioline and vinblastine
GR69783B (fr) *	1976-09-08	1982-07-07	Lilly Co Eli
US4115388A (en) *	1977-03-30	1978-09-19	Eli Lilly And Company	3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds
HU181874B (en) *	1977-08-08	1983-11-28	Lilly Co Eli	Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine

1978
- 1978-05-15 US US05/905,667 patent/US4199504A/en not_active Expired - Lifetime
1979
- 1979-05-05 PH PH22464A patent/PH14999A/en unknown
- 1979-05-08 PT PT69589A patent/PT69589A/pt unknown
- 1979-05-09 AU AU46913/79A patent/AU4691379A/en not_active Abandoned
- 1979-05-10 FR FR7911882A patent/FR2435480A1/fr active Pending
- 1979-05-10 BE BE1/9386A patent/BE876155A/fr unknown
- 1979-05-10 ZA ZA792271A patent/ZA792271B/xx unknown
- 1979-05-10 CA CA327,351A patent/CA1114816A/fr not_active Expired
- 1979-05-11 FI FI791519A patent/FI791519A/fi not_active Application Discontinuation
- 1979-05-12 GR GR59071A patent/GR73047B/el unknown
- 1979-05-14 LU LU81254A patent/LU81254A1/fr unknown
- 1979-05-14 DK DK197579A patent/DK197579A/da unknown
- 1979-05-14 EP EP81101927A patent/EP0032756A3/fr not_active Withdrawn
- 1979-05-14 EP EP79300826A patent/EP0005620A1/fr not_active Withdrawn
- 1979-05-14 EP EP81101924A patent/EP0033981A3/fr not_active Withdrawn
- 1979-05-14 ES ES480560A patent/ES480560A1/es not_active Expired
- 1979-05-14 JP JP5962979A patent/JPS54148798A/ja active Pending
- 1979-05-14 CS CS793284A patent/CS214792B2/cs unknown
- 1979-05-14 ES ES480562A patent/ES480562A1/es not_active Expired
- 1979-05-14 ES ES480561A patent/ES480561A1/es not_active Expired
- 1979-05-14 GB GB7916702A patent/GB2022080A/en not_active Withdrawn
- 1979-05-14 RO RO97514A patent/RO81682B/ro unknown
- 1979-05-15 PL PL1979222094A patent/PL120896B1/pl unknown
- 1979-05-15 DD DD79217285A patent/DD147543A5/de unknown
- 1979-05-15 DD DD79217286A patent/DD150467A5/de unknown
- 1979-05-15 PL PL21559379A patent/PL215593A1/xx unknown
- 1979-05-15 DD DD79212894A patent/DD143618A5/de unknown
- 1979-05-30 IL IL57434A patent/IL57434A0/xx unknown
- 1979-10-31 FR FR7926971A patent/FR2438052A1/fr active Pending
1980
- 1980-03-06 PH PH23731A patent/PH14904A/en unknown
- 1980-03-06 PH PH23730A patent/PH14907A/en unknown

Also Published As

Publication number	Publication date
EP0032756A3 (fr)	1981-09-09
PH14907A (en)	1982-01-29
JPS54148798A (en)	1979-11-21
GB2022080A (en)	1979-12-12
RO81682B (ro)	1983-04-30
CA1114816A (fr)	1981-12-22
PL222094A1 (fr)	1980-10-20
PL215593A1 (fr)	1980-06-16
FI791519A (fi)	1979-11-16
AU4691379A (en)	1979-11-22
IL57434A0 (en)	1979-09-30
DK197579A (da)	1979-11-16
DD150467A5 (de)	1981-09-02
ES480560A1 (es)	1980-04-01
PH14999A (en)	1982-03-22
EP0033981A2 (fr)	1981-08-19
CS214792B2 (en)	1982-05-28
PL120896B1 (en)	1982-03-31
RO81682A (fr)	1983-04-29
EP0032756A2 (fr)	1981-07-29
FR2438052A1 (fr)	1980-04-30
US4199504A (en)	1980-04-22
ES480561A1 (es)	1980-04-01
DD147543A5 (de)	1981-04-08
PH14904A (en)	1982-01-29
EP0033981A3 (fr)	1981-09-09
EP0005620A1 (fr)	1979-11-28
ZA792271B (en)	1980-12-31
FR2435480A1 (fr)	1980-04-04
GR73047B (fr)	1984-01-26
LU81254A1 (fr)	1979-09-10
ES480562A1 (es)	1980-04-01
PT69589A (en)	1979-06-01
DD143618A5 (de)	1980-09-03

Similar Documents

Publication	Publication Date	Title
BE874202A (fr)	1979-08-16	Derives d'iminoacides cycliques et leur preparation
LU80922A1 (fr)	1979-06-18	9-amino-et imino-dibenzopyrannes et leur utilisation therapeutique
LU81458A1 (fr)	1979-10-30	Phenethanolamines et leur utilisation therapeutique
MA19845A1 (fr)	1984-04-01	Nouvelles piperidinamines et leur preparation
LU80619A1 (fr)	1979-06-05	Derives heterosidiques de pleuromutiline et leur utilisation therapeutique
BE856278A (fr)	1977-12-29	Nouveaux derives d'acide penicillanique et leur utilisation therapeutique
BE875846A (fr)	1979-10-25	Derives heterocycliques et leur preparation
BE880220A (fr)	1980-05-23	1,2,4,5-tetra-alkyl-4-arylpiperidines, leur utilisation therapeutique, leur preparation et les intermediaires appropries
FR2404629B1 (fr)	1985-12-27	Nouveaux tetrapeptides et leur utilisation therapeutique
BE876238A (fr)	1979-11-14	Derives d'isopropylbenzene et leur preparation
BE868589A (fr)	1978-10-16	Nouveaux derives d'aminoacides alpha-acetyleniques et leur utilisation therapeutique
LU80719A1 (fr)	1979-04-13	Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique
LU81254A1 (fr)	1979-09-10	Dimeres pontes d'alcaloides de catharanthus et leur utilisation therapeutique
LU81437A1 (fr)	1979-09-12	2-azaergolines et 2-aza-8(ou 9)ergolenes et leur utilisation therapeutique
LU81002A1 (fr)	1979-06-18	2,3-dihydroimidazo(1,2-c)pyrimidines substituees et leur utilisation therapeutique
FR2308365A2 (fr)	1976-11-19	Derives de l'hydroxy-9 ellipticine et leur application therapeutique
FR2332979A1 (fr)	1977-06-24	Halogenures d'acides sulfamiques et leur preparation
LU81454A1 (fr)	1979-10-30	R-n-(2-phenyl-2-hydroxyethyl)-3-phenylpropylamines et leur utilisation therapeutique
BE874662A (fr)	1979-07-02	Benzocycloheptapyrannes et leur utilisation therapeutique
BE871724A (fr)	1979-03-01	4-desacetoxy-4 alpha-hydroxyindole-dihydroindoles et leur utilisation therapeutique
LU80731A1 (fr)	1979-04-13	Derives d'acides thioalcanoylalcanoiques et leur utilisation therapeutique
BE882167A (fr)	1980-09-11	(1,1-biphenyl-2-yl)-propyl- et butylamines, leur preparation et leur utilisation therapeutique
BE879631A (fr)	1980-04-25	Derives imidazolylethoxy de pyridine-5-methanols et de quinoleine-3-methanols et leur preparation
BE895664A (fr)	1983-04-16	Esters d'acides phenoxyphenoxypropioniques leur preparation et leur utilisation
BE881849A (fr)	1980-06-16	Derives de phenothiazine et leur application en therapeutique