AU703344B2 - Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface - Google Patents
Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface Download PDFInfo
- Publication number
- AU703344B2 AU703344B2 AU34103/95A AU3410395A AU703344B2 AU 703344 B2 AU703344 B2 AU 703344B2 AU 34103/95 A AU34103/95 A AU 34103/95A AU 3410395 A AU3410395 A AU 3410395A AU 703344 B2 AU703344 B2 AU 703344B2
- Authority
- AU
- Australia
- Prior art keywords
- dna
- nucleic acid
- biosensor
- film
- electrode
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU36767/99A AU3676799A (en) | 1994-08-26 | 1999-06-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to solid surface |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29663094A | 1994-08-26 | 1994-08-26 | |
US08/296630 | 1994-08-26 | ||
PCT/US1995/010630 WO1996006946A1 (fr) | 1994-08-26 | 1995-08-25 | Biocapteur et procede destines a la detection par luminescence electrophotochimique d'acides nucleiques adsorbes sur une surface solide |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU36767/99A Division AU3676799A (en) | 1994-08-26 | 1999-06-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to solid surface |
Publications (2)
Publication Number | Publication Date |
---|---|
AU3410395A AU3410395A (en) | 1996-03-22 |
AU703344B2 true AU703344B2 (en) | 1999-03-25 |
Family
ID=23142843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU34103/95A Ceased AU703344B2 (en) | 1994-08-26 | 1995-08-25 | Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0777741A4 (fr) |
JP (1) | JPH10509025A (fr) |
AU (1) | AU703344B2 (fr) |
CA (1) | CA2198489A1 (fr) |
WO (1) | WO1996006946A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5786141A (en) * | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
CN1192097C (zh) * | 1995-03-10 | 2005-03-09 | 梅索磅秤技术有限公司 | 多阵列、多特异性的电化学发光检验 |
US6140045A (en) * | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
FR2762013B1 (fr) * | 1997-04-09 | 1999-06-04 | Cis Bio Int | Systemes de detection d'hybridation d'acides nucleiques, leur procede de preparation et leurs utilisations |
US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
US7935481B1 (en) | 1999-07-26 | 2011-05-03 | Osmetech Technology Inc. | Sequence determination of nucleic acids using electronic detection |
US6518024B2 (en) | 1999-12-13 | 2003-02-11 | Motorola, Inc. | Electrochemical detection of single base extension |
AU2907201A (en) * | 1999-12-09 | 2001-06-18 | Motorola, Inc. | Methods and compositions relating to electrical detection of nucleic acid reactions |
US6824669B1 (en) | 2000-02-17 | 2004-11-30 | Motorola, Inc. | Protein and peptide sensors using electrical detection methods |
US6706479B2 (en) * | 2000-10-05 | 2004-03-16 | Virginia Tech Intellectual Properties, Inc. | Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips |
WO2005016115A2 (fr) | 2003-01-23 | 2005-02-24 | Montana State University | Biocapteurs faisant intervenir des ligands immobilises sur des dendrimeres et utilisation de ceux-ci |
WO2005005952A2 (fr) | 2003-05-13 | 2005-01-20 | The Trustees Of Boston College | Detection electrocatalytique de l'hybridation d'acides nucleiques |
US7741033B2 (en) * | 2003-05-13 | 2010-06-22 | Trustees Of Boston College | Electrocatalytic nucleic acid hybridization detection |
WO2006075497A1 (fr) * | 2004-12-21 | 2006-07-20 | Kyoto University | Sonde, dispositif d'identification de region nucleotidique et procede d'identification de region nucleotidique |
CN102216762B (zh) | 2008-09-02 | 2016-02-10 | 多伦多大学董事局 | 纳米结构的微电极以及集成所述微电极的生物传感器件 |
EP2663857B1 (fr) | 2011-01-11 | 2018-12-12 | The Governing Council Of The University Of Toronto | Procédé de détection de protéines |
WO2012122564A2 (fr) | 2011-03-10 | 2012-09-13 | Xagenic, Inc. | Dispositifs et méthodes de diagnostic et de préparation d'échantillons |
BR112018001956A2 (pt) | 2015-08-20 | 2018-09-11 | Hoffmann La Roche | ?método de medição de analitos e kit? |
EP3427057A1 (fr) | 2016-03-07 | 2019-01-16 | H. Hoffnabb-La Roche Ag | Détection d'anticorps anti-p53 |
JP7068323B2 (ja) | 2017-02-02 | 2022-05-16 | エフ.ホフマン-ラ ロシュ アーゲー | 少なくとも2種のペグ化された分析物特異的結合剤を使用する免疫アッセイ |
CN111936522A (zh) | 2018-04-18 | 2020-11-13 | 豪夫迈·罗氏有限公司 | 新型抗胸苷激酶抗体 |
EP3844503A1 (fr) | 2018-08-31 | 2021-07-07 | F. Hoffmann-La Roche AG | Thymidine kinase (tk-1) dans la détermination d'indices de pronostic pour le dlbcl |
CN114144674A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | P物质作为用于子宫内膜异位症的非侵入性诊断的血液生物标志物 |
WO2021013784A1 (fr) | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a8 utilisée en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
CN114144675A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a9作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
EP4004555A1 (fr) | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a6 en tant que biomarqueur du sang pour le diagnostic non invasif de l'endométriose |
BR112022001140A2 (pt) | 2019-07-22 | 2022-03-15 | Hoffmann La Roche | Métodos para avaliar se um paciente tem endometriose ou está em risco de desenvolver endometriose, selecionar um paciente para terapia e monitorar um paciente que sofre de endometriose ou que está sendo tratado para endometriose |
WO2021094409A1 (fr) | 2019-11-15 | 2021-05-20 | F. Hoffmann-La Roche Ag | Dérivation d'antibiotiques de bêta-lactame pour des mesures par spectrométrie de masse dans des échantillons de patients |
CN111272742B (zh) * | 2020-03-06 | 2022-11-08 | 安徽大学 | 基于金属有机凝胶复合材料和金属有机框架的电致化学发光传感器及其制备和检测方法 |
US20230406909A1 (en) | 2020-11-02 | 2023-12-21 | Roche Diagnostics Operations, Inc. | Sars-cov-2 nucleocapsid antibodies |
WO2022207628A1 (fr) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf comme biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
WO2022207685A1 (fr) | 2021-04-01 | 2022-10-06 | F. Hoffmann-La Roche Ag | Psp94 utilisée en tant que biomarqueur sanguin pour le diagnostic non invasif de l'endométriose |
CN117337394A (zh) | 2021-05-17 | 2024-01-02 | 豪夫迈·罗氏有限公司 | sFRP4作为血液生物标志物用于子宫腺肌病的非侵入性诊断 |
WO2023072904A1 (fr) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Anticorps monoclonaux spécifiques du rbd du sars-cov-2 |
WO2023131594A1 (fr) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Dérivatisation de composés dans des échantillons de patients pour la pharmacovigilance thérapeutique (tdm) |
WO2023247752A1 (fr) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Procédé de diagnostic de l'endométriose et de classification du stade de l'endométriose |
WO2024017985A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine 1 de liaison au facteur de croissance des fibroblastes (fgfbp1) utilisée en tant que biomarqueur (sanguin) pour le diagnostic du syndrome des ovaires polykystiques |
WO2024017982A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriène a4 hydrolase (lta4h) en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
WO2024017983A1 (fr) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Protéine de type météorine (metrnl) utilisée en tant que biomarqueur (sang) pour le diagnostic du syndrome des ovaires polykystiques |
CN115414930B (zh) * | 2022-08-26 | 2023-10-31 | 重庆医科大学 | Ru(bpy)32+阳极或阴极共反应物及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1258580A (fr) * | 1967-12-28 | 1971-12-30 | ||
US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
US5124022A (en) * | 1989-08-23 | 1992-06-23 | Aluminum Company Of America | Electrolytic capacitor and method of making same |
US5019343A (en) * | 1989-12-15 | 1991-05-28 | W. R. Grace & Co.-Conn. | Control of corrosion in aqueous systems using certain phosphonomethyl amines |
US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
-
1995
- 1995-08-25 CA CA002198489A patent/CA2198489A1/fr not_active Abandoned
- 1995-08-25 EP EP95930881A patent/EP0777741A4/fr not_active Withdrawn
- 1995-08-25 WO PCT/US1995/010630 patent/WO1996006946A1/fr not_active Application Discontinuation
- 1995-08-25 AU AU34103/95A patent/AU703344B2/en not_active Ceased
- 1995-08-25 JP JP8508822A patent/JPH10509025A/ja active Pending
Non-Patent Citations (1)
Title |
---|
ANAL. CHEM, 66(6) PP.769-777(1994) * |
Also Published As
Publication number | Publication date |
---|---|
CA2198489A1 (fr) | 1996-03-07 |
AU3410395A (en) | 1996-03-22 |
EP0777741A1 (fr) | 1997-06-11 |
JPH10509025A (ja) | 1998-09-08 |
EP0777741A4 (fr) | 1999-01-13 |
WO1996006946A1 (fr) | 1996-03-07 |
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