AU3410395A - Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface - Google Patents

Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface

Info

Publication number
AU3410395A
AU3410395A AU34103/95A AU3410395A AU3410395A AU 3410395 A AU3410395 A AU 3410395A AU 34103/95 A AU34103/95 A AU 34103/95A AU 3410395 A AU3410395 A AU 3410395A AU 3410395 A AU3410395 A AU 3410395A
Authority
AU
Australia
Prior art keywords
biosensor
nucleic acid
solid surface
chemiluminescent detection
acid adsorbed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU34103/95A
Other versions
AU703344B2 (en
Inventor
Allen J Bard
Xiao-Hong Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IGEN International Inc
Original Assignee
IGEN Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IGEN Inc filed Critical IGEN Inc
Publication of AU3410395A publication Critical patent/AU3410395A/en
Assigned to IGEN INTERNATIONAL, INC. reassignment IGEN INTERNATIONAL, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: IGEN, INC.
Application granted granted Critical
Publication of AU703344B2 publication Critical patent/AU703344B2/en
Priority to AU36767/99A priority Critical patent/AU3676799A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
AU34103/95A 1994-08-26 1995-08-25 Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface Ceased AU703344B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU36767/99A AU3676799A (en) 1994-08-26 1999-06-25 Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to solid surface

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29663094A 1994-08-26 1994-08-26
US08/296630 1994-08-26
PCT/US1995/010630 WO1996006946A1 (en) 1994-08-26 1995-08-25 Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU36767/99A Division AU3676799A (en) 1994-08-26 1999-06-25 Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to solid surface

Publications (2)

Publication Number Publication Date
AU3410395A true AU3410395A (en) 1996-03-22
AU703344B2 AU703344B2 (en) 1999-03-25

Family

ID=23142843

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34103/95A Ceased AU703344B2 (en) 1994-08-26 1995-08-25 Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface

Country Status (5)

Country Link
EP (1) EP0777741A4 (en)
JP (1) JPH10509025A (en)
AU (1) AU703344B2 (en)
CA (1) CA2198489A1 (en)
WO (1) WO1996006946A1 (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786141A (en) * 1994-08-26 1998-07-28 Bard; Allen J. Electrogenerated chemiluminescence labels for analysis and/or referencing
US6673533B1 (en) 1995-03-10 2004-01-06 Meso Scale Technologies, Llc. Multi-array multi-specific electrochemiluminescence testing
US6140045A (en) 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
US6207369B1 (en) 1995-03-10 2001-03-27 Meso Scale Technologies, Llc Multi-array, multi-specific electrochemiluminescence testing
US6066448A (en) * 1995-03-10 2000-05-23 Meso Sclae Technologies, Llc. Multi-array, multi-specific electrochemiluminescence testing
US6319670B1 (en) 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
FR2762013B1 (en) 1997-04-09 1999-06-04 Cis Bio Int DETECTION SYSTEMS FOR NUCLEIC ACID HYBRIDIZATION, PREPARATION METHOD THEREOF AND USES THEREOF
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
WO2001007665A2 (en) 1999-07-26 2001-02-01 Clinical Micro Sensors, Inc. Sequence determination of nucleic acids using electronic detection
WO2001042508A2 (en) * 1999-12-09 2001-06-14 Motorola, Inc. Methods and compositions relating to electrical detection of nucleic acid reactions
US6518024B2 (en) 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US6824669B1 (en) 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US6706479B2 (en) * 2000-10-05 2004-03-16 Virginia Tech Intellectual Properties, Inc. Bio-chip, photoluminescent methods for identifying biological material, and apparatuses for use with such methods and bio-chips
WO2005016115A2 (en) 2003-01-23 2005-02-24 Montana State University Biosensors utilizing dendrimer-immobilized ligands and their use thereof
DE602004023604D1 (en) 2003-05-13 2009-11-26 Trustees Boston College ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION
US7741033B2 (en) * 2003-05-13 2010-06-22 Trustees Of Boston College Electrocatalytic nucleic acid hybridization detection
JPWO2006075497A1 (en) * 2004-12-21 2008-06-12 国立大学法人京都大学 Probe unit, nucleotide region identification apparatus, and nucleotide region identification method
ES2636664T3 (en) 2008-09-02 2017-10-06 The Governing Council Of The University Of Toronto Nanostructured microelectrodes and biodetection devices that incorporate them
ES2704685T3 (en) 2011-01-11 2019-03-19 Governing Council Univ Toronto Method for protein detection
US9580742B2 (en) 2011-03-10 2017-02-28 Shana O. Kelley Diagnostic and sample preparation devices and methods
CN117491623A (en) 2015-08-20 2024-02-02 豪夫迈·罗氏有限公司 Particle-based immunoassays using pegylated analyte-specific binding agents
CN108780092A (en) 2016-03-07 2018-11-09 豪夫迈·罗氏有限公司 The detection of anti-p53 antibody
EP3577460B1 (en) 2017-02-02 2021-01-20 Roche Diagnostics GmbH Immunoassay using at least two pegylated analyte-specific binding agents
CN111936522A (en) 2018-04-18 2020-11-13 豪夫迈·罗氏有限公司 Novel anti-thymidine kinase antibodies
WO2020043868A1 (en) 2018-08-31 2020-03-05 F. Hoffmann-La Roche Ag Thymidine kinase (tk-1) in prognostic indices for dlbcl
EP4004555A1 (en) 2019-07-22 2022-06-01 F. Hoffmann-La Roche AG S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021013784A1 (en) 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis
BR112022000172A2 (en) 2019-07-22 2022-02-22 Hoffmann La Roche Methods for assessing whether a patient has endometriosis, for selecting a patient for therapy, and for monitoring a patient
CN114144674A (en) 2019-07-22 2022-03-04 豪夫迈·罗氏有限公司 Substance P as a blood biomarker for the non-invasive diagnosis of endometriosis
JP7315781B2 (en) 2019-07-22 2023-07-26 エフ. ホフマン-ラ ロシュ アーゲー S100A12 as a blood biomarker for non-invasive diagnosis of endometriosis
EP4058459A1 (en) 2019-11-15 2022-09-21 F. Hoffmann-La Roche AG Derivatization of beta-lactam antibiotics for massspec measurements in patient samples
CN111272742B (en) * 2020-03-06 2022-11-08 安徽大学 Electrochemiluminescence sensor based on metal organic gel composite material and metal organic framework and preparation and detection methods thereof
WO2022090455A1 (en) 2020-11-02 2022-05-05 F. Hoffmann-La Roche Ag Sars-cov-2 nucleocapsid antibodies
WO2022207628A1 (en) 2021-03-30 2022-10-06 F. Hoffmann-La Roche Ag Scf as blood biomarker for the non-invasive diagnosis of endometriosis
CN117099001A (en) 2021-04-01 2023-11-21 豪夫迈·罗氏有限公司 PSP94 as blood biomarker for non-invasive diagnosis of endometriosis
EP4341700A1 (en) 2021-05-17 2024-03-27 F. Hoffmann-La Roche AG Sfrp4 as blood biomarker for the non-invasive diagnosis of adenomyosis
WO2023072904A1 (en) 2021-10-26 2023-05-04 F. Hoffmann-La Roche Ag Monoclonal antibodies specific for sars-cov-2 rbd
WO2023131594A1 (en) 2022-01-05 2023-07-13 F. Hoffmann-La Roche Ag Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm)
WO2023247752A1 (en) 2022-06-23 2023-12-28 F. Hoffmann-La Roche Ag Method for diagnosing endometriosis and for classifying the stage of endometriosis
WO2024017983A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
WO2024017982A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
WO2024017985A1 (en) 2022-07-22 2024-01-25 F. Hoffmann-La Roche Ag Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome
CN115414930B (en) * 2022-08-26 2023-10-31 重庆医科大学 Ru(bpy) 32+ Anode or cathode coreactant and method for producing same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1258580A (en) * 1967-12-28 1971-12-30
US5238808A (en) * 1984-10-31 1993-08-24 Igen, Inc. Luminescent metal chelate labels and means for detection
US5124022A (en) * 1989-08-23 1992-06-23 Aluminum Company Of America Electrolytic capacitor and method of making same
US5019343A (en) * 1989-12-15 1991-05-28 W. R. Grace & Co.-Conn. Control of corrosion in aqueous systems using certain phosphonomethyl amines
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection

Also Published As

Publication number Publication date
EP0777741A1 (en) 1997-06-11
CA2198489A1 (en) 1996-03-07
EP0777741A4 (en) 1999-01-13
WO1996006946A1 (en) 1996-03-07
JPH10509025A (en) 1998-09-08
AU703344B2 (en) 1999-03-25

Similar Documents

Publication Publication Date Title
AU3410395A (en) Biosensor for and method of electrogenerated chemiluminescent detection of nucleic acid adsorbed to a solid surface
AU1193788A (en) Method of assaying of nucleic acids, a reagent combination and kit therefore
AU6972387A (en) Detection of microorganisms in a nucleic acid containing sample
IL79111A0 (en) Compositions and methods for functionalizing nucleic acids
AU7679394A (en) A method of nucleic acid sequencing
AU5443286A (en) Test kit for determining the presence of organic materials and method of utilizing same
AU1316095A (en) Method of determining nucleic acid hybridisation
AU7975091A (en) Method of identifying compounds useful as antiparasite drugs
AU6124086A (en) Method and kit for performing nucleic acid hybridization assays
AU8505091A (en) Nucleic acid detection method using particle agglutination
AU5838690A (en) Method for detecting specific nucleic acid sequences and applications of same
AU1450699A (en) Methods of nucleic acid detection
PL307854A1 (en) Method of obtaining dust-free enzyme
AU2514195A (en) Method of rapid analyte detection
AU7203687A (en) Method of assay of inhibin
AU6391186A (en) Method for the production of polymethyl methacrylate
AU6513790A (en) Apparatus for detection of an immobilized analyte
AU5516686A (en) Assay for degradable substrates by electrochemical detection of redox species
AU8405598A (en) Assay to detect inhibitors of i-kappa-b proteolyse
AU3639395A (en) Method for detecting antibodies to thrombomodulin in patients
IL105894A (en) Method for the detection of nucleic acid sequence by using a detection ensemble and an amplification ensemble
AU4666785A (en) Method and kit to detect gum disease by the presence of collagenase
AU7137996A (en) Materials and methods relating to the transfer of nucleic acid into quiescent cells
EP0285998A3 (en) Method and reagent for determination of dehydrogenase or its substrate
AU4400189A (en) Reagents and methods for determination of analytes